Human RNA Editing Track Settings
 
Human RNA Editing from the DAtabase of RNa EDiting   (All mRNA and EST tracks)

Display mode:      Duplicate track
Data schema/format description and download
Assembly: Human Feb. 2009 (GRCh37/hg19)
Data last updated at UCSC: 2011-12-22

Description

This track provides information on RNA nucleotides that are edited after transcription and their corresponding genomic coordinates. Only post-transcriptional editing that results in small changes to the identity of a nucleic acid are included in this track; it does not include other RNA processing such as splicing or methylation. The track contains information on A-to-I (adenosine-to-inosine) and C-to-U (cytidine-to-uridine) editing that occur due to deamination by ADAR and APOBEC enzymes, respectively. Most of the data in this track are on A-to-I editing, which is known to be highly abundant in humans.

Display

Track items are colored depending on their occurrence within RNA transcripts:

  • Dark Green: 5' UTR
  • Blue: CDS
  • Red: Intron
  • Deep Pink: 3' UTR
  • Black: Other (exon/intron status is unclear or unknown)

Methods

The data were obtained from several research papers on RNA editing and were mapped to the reference genome. More information can be obtained from DARNED database.

References:

Kiran A, Baranov PV. DARNED: a DAtabase of RNa EDiting in humans. Bioinformatics. 2010 Jul 15;26(14):1772-6. PMID: 20547637