UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	M01E11.3	M01E11.3	0	chrI 5,574,995	contains similarity to Pfam domain PF08585 Domain of unknown function (DUF1767) contains similarity to Interpro domain IPR013894 (Region of unknown function DUF1767)
2	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
3	H05L14.2	H05L14.2	n/a	chrI 7,987,359	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
4	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
5	R06C7.2	R06C7.2	n/a	chrI 7,234,078	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86KG8
6	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
7	tbx-36	ZK829.5	n/a	chrIV 11,951,305	C. elegans TBX-36 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
8	mes-1	F54F7.5	n/a	chrX 11,859,856	The mes-1 gene encodes a receptor tyrosine kinase-like protein that is required for unequal cell divisions in the early embryonic germline; during embryonic cell divisions, mes-1 is involved in positioning of the early mitotic spindle and of associated P granules.
9	T10B5.8	T10B5.8	n/a	chrV 1,843,425	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
10	C46F4.1	C46F4.1	n/a	chrX 5,933,527	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
11	T19H5.1	T19H5.1	n/a	chrII 9,473,432	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
12	W03G9.2	W03G9.2	n/a	chrI 4,963,346	contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR001545 (Gonadotropin, beta chain)
13	ZC155.4	ZC155.4	n/a	chrIII 5,213,465	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
14	clec-223	C03E10.5	n/a	chrV 11,275,618	C. elegans CLEC-223 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR008160 (Collagen triple helix repeat)
15	F30F8.3	F30F8.3	n/a	chrI 7,836,374	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
16	fut-3	F59E12.13	n/a	chrII 5,658,783	C. elegans FUT-3 protein; contains similarity to Pfam domain PF00852 Glycosyltransferase family 10 (fucosyltransferase) contains similarity to Interpro domain IPR001503 (Glycosyl transferase, family 10)
17	F52C6.4	F52C6.4	n/a	chrII 1,923,563	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
18	B0393.6	B0393.6	n/a	chrIII 4,781,174	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
19	srw-98	K04F1.3	n/a	chrV 1,677,402	C. elegans SRW-98 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
20	gei-12	F52D2.4	n/a	chrX 1,988,059	gei-12 encodes a novel protein that affects embryonic viability and development of the hypodermis; interacts with GEX-3 in yeast two-hybrid assays, and is expressed in all somatic cells.
21	C31H1.8	C31H1.8	n/a	chrIV 5,812,882	contains similarity to Homo sapiens Protocadherin 15; ENSEMBL:ENSP00000378832
22	T27E7.5	T27E7.5	n/a	chrIV 14,537,655	contains similarity to Bacillus stearothermophilus D-alanyl-D-alanine carboxypeptidase precursor (EC 3.4.16.4) (DD-speptidase) (DD-carboxypeptidase) (CPase) (PBP5).; SW:DACA_BACST
23	fbxb-35	F07E5.2	n/a	chrII 2,052,208	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
24	K02A2.1	K02A2.1	n/a	chrII 7,435,459	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
25	uri-1	C55B7.5	n/a	chrI 6,495,201	uri-1 encodes a molecular chaperone orthologous to the unconventional prefoldin RPB5 (RNA polymerase subunit 5) interactor, URI; in C.elegans, URI-1 activity is required for suppressing endogenous genotoxic DNA damage and thus, is essential for maintenance of genome integrity (DNA stability) and progression through the mitotic and meiotic cell cycles, particularly during germ cell development; URI-1 activity is also required for development of some somatic structures, such as the vulva, and for RNA interference; uri-1 mRNA is germline-enriched.
26	srh-52	R08H2.7	n/a	chrV 15,375,587	C. elegans SRH-52 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	C24H10.4	C24H10.4	n/a	chrX 5,058,527
28	F20D1.7	F20D1.7	n/a	chrX 14,989,294	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR007110 (Immunoglobulin-like)
29	ZK287.7	ZK287.7	n/a	chrV 9,693,782	contains similarity to Homo sapiens Isoform 2 of RNA pseudouridylate synthase domain-containing protein 3; ENSEMBL:ENSP00000380410
30	E02H9.7	E02H9.7	n/a	chrIII 2,445,442	contains similarity to Homo sapiens Uncharacterized protein MUC17 (Fragment); ENSEMBL:ENSP00000368750
31	srg-4	T12A2.12	n/a	chrIII 6,261,094	C. elegans SRG-4 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
32	pqn-62	T03G11.1	n/a	chrX 5,200,980	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
33	str-19	T23D5.7	n/a	chrV 15,743,832	C. elegans STR-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	T20F10.4	T20F10.4	n/a	chrI 10,305,153	contains similarity to Streptococcus mutans Putative 16S rRNA processing protein.; TR:Q8DUN7
35	B0304.2	B0304.2	n/a	chrII 4,524,073
36	clec-227	F08H9.5	n/a	chrV 14,473,432	C. elegans CLEC-227 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	F26H9.4	F26H9.4	n/a	chrI 9,306,326	contains similarity to Pfam domain PF01467 Cytidylyltransferase contains similarity to Interpro domains IPR005248 (Probable nicotinate-nucleotide adenylyltransferase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004820 (Cytidylyltransferase)
38	C36F7.2	C36F7.2	n/a	chrI 9,551,413	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
39	srw-55	T05G11.6	n/a	chrV 15,939,538	C. elegans SRW-55 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
40	sru-48	T03G11.2	n/a	chrX 5,180,802	C. elegans SRU-48 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
41	D1054.3	D1054.3	n/a	chrV 10,772,116	contains similarity to Pfam domains PF04969 (CS domain) , PF05002 (SGS domain) contains similarity to Interpro domains IPR007699 (SGS), IPR008978 (HSP20-like chaperone), IPR017447 (CS), IPR007052 (CS domain)
42	F02H6.2	F02H6.2	n/a	chrIV 14,197,604	contains similarity to Trichomonas vaginalis G3 Putative uncharacterized protein.; TR:A2F8N8
43	T19H5.2	T19H5.2	n/a	chrII 9,475,595	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001176 (1-aminocyclopropane-1-carboxylate synthase), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
44	clec-127	W10G11.5	n/a	chrII 3,568,702	C. elegans CLEC-127 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
45	C42C1.8	C42C1.8	n/a	chrIV 12,292,136	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
46	srd-18	F53F1.10	n/a	chrV 13,426,143	C. elegans SRD-18 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
47	C49C8.3	C49C8.3	n/a	chrIV 8,644,987
48	srbc-68	T24A6.13	n/a	chrV 3,546,145	C. elegans SRBC-68 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
49	age-1	B0334.8	n/a	chrII 11,523,196	age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects.
50	fbxa-197	T06C12.4	n/a	chrV 15,868,291	C. elegans FBXA-197 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)