UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T10B11.2	T10B11.2	0	chrI 6,934,027	contains similarity to Pfam domain PF00781 Diacylglycerol kinase catalytic domain (presumed) contains similarity to Interpro domain IPR001206 (Diacylglycerol kinase, catalytic region)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	F14H12.8	F14H12.8	n/a	chrX 4,363,765
4	Y6E2A.5	Y6E2A.5	n/a	chrV 15,717,512	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domain IPR007883 (Protein of unknown function DUF713)
5	pld-1	C04G6.3	n/a	chrII 5,087,755	C. elegans PLD-1 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF00614 (Phospholipase D Active site motif) (2), PF00787 (PX domain) contains similarity to Interpro domains IPR016555 (Phospholipase D, eukaryota), IPR001683 (Phox-like), IPR001849 (Pleckstrin-like), IPR001736 (Phospholipase D/Transphosphatidylase), IPR015679 (Phospholipase D)
6	mdt-4	ZK546.13	n/a	chrII 4,943,020	C. elegans MDT-4 protein ; contains similarity to Drosophila melanogaster Flybase gene name is MED4-PA;; FLYBASE:CG8609
7	acbp-5	T12D8.3	n/a	chrIII 13,640,695	C. elegans ACBP-5 protein; contains similarity to Pfam domains PF00023 (Ankyrin repeat) (2), PF00887 (Acyl CoA binding protein) contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR002110 (Ankyrin), IPR000582 (Acyl-CoA-binding protein, ACBP)
8	F23F1.6	F23F1.6	n/a	chrII 36,279	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR004755 (Cationic amino acid transport permease), IPR004841 (Amino acid permease-associated region), IPR002293 (Amino acid/polyamine transporter I)
9	ZC443.1	ZC443.1	n/a	chrV 12,809,256	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
10	W06B4.2	W06B4.2	n/a	chrII 4,469,593	contains similarity to Pfam domain PF01869 BadF/BadG/BcrA/BcrD ATPase family contains similarity to Interpro domain IPR002731 (ATPase, BadF/BadG/BcrA/BcrD type)
11	fbxa-184	F45C12.8	n/a	chrII 1,710,841	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
12	sra-37	T21H8.2	n/a	chrX 13,892,086	C. elegans SRA-37 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
13	C13F10.6	C13F10.6	n/a	chrV 7,220,078
14	twk-2	T12C9.3	n/a	chrII 4,447,199	twk-2 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-2 in C. elegans development and/or behavior is not yet known, but TWK-2 may function redundantly with other TWK channels; TWK-2 is expressed in a subset of neurons.
15	wrt-7	ZK1037.10	n/a	chrV 15,336,119	wrt-7 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Wart domain, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut WRT-7 into two halves and then covalently link cholesterol to the C-terminus of the Wart domain; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-7 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
16	lys-9	C54C8.6	n/a	chrI 12,455,280	C. elegans LYS-9 protein; contains similarity to Interpro domain IPR017853 (Glycoside hydrolase, catalytic core)
17	srh-20	C02E7.3	n/a	chrV 4,925,540	C. elegans SRH-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	ric-3	T14A8.1	n/a	chrIV 7,819,689	The ric-3 gene encodes a novel, highly charged protein with two transmembrane domains and extensive coiled-coil domains; it is necessary for the function of at least four nicotinic acetylcholine receptors; specifically, it is needed for assembly or trafficking of the DEG-3 nicotinic acetylcholine receptor.
19	C33A12.12	C33A12.12	n/a	chrIV 9,483,553	contains similarity to Interpro domains IPR000225 (Armadillo), IPR016024 (Armadillo-type fold)
20	R09D1.11	R09D1.11	n/a	chrII 9,467,636	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
21	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
22	W05H12.2	W05H12.2	n/a	chrI 13,412,326	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
23	sgo-1	C33H5.15	n/a	chrIV 7,795,579	C. elegans SGO-1 protein; contains similarity to Pfam domain PF07557 Shugoshin C terminus contains similarity to Interpro domain IPR011515 (Shugoshin, C-terminal)
24	F32B4.8	F32B4.8	n/a	chrI 11,504,367	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN)
25	duo-1	F38B7.5	n/a	chrV 11,556,440	C. elegans DUO-1 protein; contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02338 (OTU-like cysteine protease) contains similarity to Interpro domains IPR003323 (Ovarian tumour, otubain), IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
26	C34G6.5	C34G6.5	n/a	chrI 5,873,231	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
27	F42A9.6	F42A9.6	n/a	chrIV 8,610,474
28	srsx-26	C51E3.1	n/a	chrV 10,149,791	C. elegans SRSX-26 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
29	cdc-6	C43E11.10	n/a	chrI 4,269,180	cdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12.
30	aat-8	F28F9.4	n/a	chrIV 3,863,573	aat-8 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-8 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-8 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
31	W06D4.4	W06D4.4	n/a	chrI 9,061,846	contains similarity to Interpro domain IPR014644 (Protein arginine N-methyltransferase)
32	F32D8.3	F32D8.3	n/a	chrV 10,887,380	F32D8.3 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; F32D8.3 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; F32D8.3 has no obvious function in mass RNAi assays.
33	F59A1.13	F59A1.13	n/a	chrV 17,689,072	contains similarity to Pfam domains PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF02377 (Dishevelled specific domain) contains similarity to Interpro domains IPR003351 (Dishevelled protein), IPR011991 (Winged helix repressor DNA-binding), IPR001478 (PDZ/DHR/GLGF), IPR015506 (Dishevelled related protein), IPR008339 (Dishevelled region), IPR000591 (Pleckstrin/ G-protein, interacting region)
34	ZK792.5	ZK792.5	n/a	chrIV 11,686,516	contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR002952 (Eggshell protein), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
35	C06E1.8	C06E1.8	n/a	chrIII 8,596,527	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
36	F07A11.1	F07A11.1	n/a	chrII 11,589,926	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000357794
37	srd-26	T02B5.4	n/a	chrV 14,162,174	C. elegans SRD-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	ugt-30	T01G5.2	n/a	chrV 15,123,493	C. elegans UGT-30 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
39	ulp-1	T10F2.3	n/a	chrIII 5,167,689	C. elegans ULP-1 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
40	thoc-3	F32H2.4	n/a	chrI 8,972,046	C. elegans THOC-3 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
41	nekl-2	ZC581.1	n/a	chrI 6,664,152	nekl-2 encodes a putative serine/threonine protein kinase orthologous to Aspergillus nidulans nimA and human NEK8 (OMIM:609799), and paralogous to C. elegans D1044.3, D1044.8, F19H6.1, and Y39G10AR.3; nekl-2 interacts with two or more components of the EGF/RAS signalling pathway, and is required for such signalling in vulval development.
42	F47B8.6	F47B8.6	n/a	chrV 14,329,569	contains similarity to Drosophila heteroneura Aminopeptidase N (Fragment).; TR:O61534
43	T14B4.8	T14B4.8	n/a	chrII 6,720,967
44	Y51B9A.8	Y51B9A.8	n/a	chrII 9,399,270	contains similarity to Pfam domains PF04942 (CC domain) (2), PF01549 (ShK domain-like) contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
45	clec-59	ZK666.5	n/a	chrII 10,478,656	C. elegans CLEC-59 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
46	K02E2.7	K02E2.7	n/a	chrV 20,380,450	contains similarity to Homo sapiens RB1-inducible coiled-coil protein 1; ENSEMBL:ENSP00000025008
47	C09G9.7	C09G9.7	n/a	chrIV 8,878,734	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
48	ZK673.3	ZK673.3	n/a	chrII 10,451,229	ZK673.3 encodes a protein with a THAP or THAP-like domain required for embryonic development; other proteins with THAP or THAP-like domains include LIN-15A, LIN-15B, LIN-36, and HIM-17 (which all interact with LIN-35/Rb), as well as CDC-14B, CTB-1, GON-14, and ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1.
49	try-2	C07G1.1	n/a	chrIV 8,213,133	try-2 encodes a homolog of human TRYP1 and ELA2; mutation of human TRYP1 or ELA2 leads, respectively, to hereditary pancreatitis (OMIM:276000) or cyclic haematopoiesis (OMIM:162800).
50	nhr-140	C33G8.9	n/a	chrV 6,988,762	C. elegans NHR-140 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)