UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T07F8.2	T07F8.2	0	chrII 7,145,876	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
2	W08F4.7	W08F4.7	n/a	chrII 576,333
3	cdr-3	C54D10.2	n/a	chrV 12,416,844	C. elegans CDR-3 protein; contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR010987 (Glutathione S-transferase, C-terminal-like)
4	pxd-1	C36E8.3	n/a	chrIII 4,008,029	C. elegans PXD-1 protein ; contains similarity to Aedes aegypti Tumor endothelial marker 7.; TR:Q16R67
5	T24B8.4	T24B8.4	n/a	chrII 9,067,183	contains similarity to Pfam domain PF02205 WH2 motif contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003124 (Actin-binding WH2)
6	F52G3.1	F52G3.1	n/a	chrX 16,968,223	contains similarity to Pfam domain PF07001 BAT2 N-terminus contains similarity to Interpro domains IPR009738 (BAT2, N-terminal), IPR000694 (Proline-rich region)
7	F53G12.4	F53G12.4	n/a	chrI 135,809
8	syd-2	F59F5.6	n/a	chrX 10,552,111	syd-2 encodes alpha-liprin, a member of the liprin family of proteins that interact with LAR (leukocyte common antigen related)-type receptor tyrosine phosphatases (RPTPs) to facilitate clustering of RPTPs to focal adhesions; SYD-2 is required for establishing normal presynaptic density, and is expressed in all neurons and muscles; SYD-2 is required cell autonomously in neurons for differentiation of presynaptic active zones, where SYD-2 is localized.
9	dpy-26	C25G4.5	n/a	chrIV 12,448,610	dpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array.
10	C35D10.12	C35D10.12	n/a	chrIII 4,873,622	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR011644 (Haem NO binding), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
11	F11C1.1	F11C1.1	n/a	chrX 12,988,210	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domain IPR010625 (CHCH)
12	cyp-33E2	F42A9.5	n/a	chrIV 8,613,501	C. elegans CYP-33E2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
13	F22E5.11	F22E5.11	n/a	chrII 2,644,695	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
14	K03H4.1	K03H4.1	n/a	chrV 13,151,458	contains similarity to Helicobacter pylori Transposase OrfB.; TR:Q93C83
15	F44D12.2	F44D12.2	n/a	chrIV 10,015,214	contains similarity to Pfam domain PF01064 Activin types I and II receptor domain contains similarity to Interpro domain IPR000472 (TGF-beta receptor/activin receptor, type I/II)
16	F21G4.6	F21G4.6	n/a	chrX 9,913,063	F21G4.6 is orthologous to the human gene HUNTINGTIN (HD; OMIM:143100), which when mutated leads to disease.
17	ZK1321.1	ZK1321.1	n/a	chrII 9,754,525	contains similarity to Sulfolobus sp NOB8H2 Hypothetical protein.; TR:O93705
18	str-214	C31A11.9	n/a	chrV 16,316,238	C. elegans STR-214 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	xrn-2	Y48B6A.3	n/a	chrII 14,160,796	C. elegans XRN-2 protein; contains similarity to Pfam domain PF03159 XRN 5'-3' exonuclease N-terminus contains similarity to Interpro domains IPR017151 (5'-3' exoribonuclease 2), IPR004859 (Putative 5-3 exonuclease), IPR002952 (Eggshell protein), IPR001878 (Zinc finger, CCHC-type)
20	grl-29	T24A6.18	n/a	chrV 3,554,921	grl-29 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-29 is expressed in larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
21	T04F8.6	T04F8.6	n/a	chrX 11,669,654	contains similarity to Interpro domain IPR011992 (EF-Hand type)
22	F20B4.3	F20B4.3	n/a	chrX 17,706,033
23	dsl-2	W09G12.1	n/a	chrIV 1,203,808	dsl-2 encodes a putative transmembrane protein whose extracellular domain has single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-2 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
24	srz-14	K05D4.3	n/a	chrV 16,184,163	C. elegans SRZ-14 protein ;
25	srw-108	R11G11.5	n/a	chrV 528,386	C. elegans SRW-108 protein ;
26	ceh-31	C33D12.1	n/a	chrX 3,069,626	ceh-31 encodes a protein containing a homeobox domain.
27	F31A9.4	F31A9.4	n/a	chrX 1,779,978
28	lrx-1	T04H1.6	n/a	chrV 12,253,997	lrx-1 encodes a protein that contains four class A low-density lipoprotein receptor domains.
29	unc-108	F53F10.4	n/a	chrI 3,825,732	unc-108 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events.
30	F59B2.8	F59B2.8	n/a	chrIII 9,008,958	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
31	R06A4.8	R06A4.8	n/a	chrII 14,354,036	R06A4.8 is orthologous to the human gene GLYCOGEN DEBRANCHING ENZYME ISOFORM 6 (AGL; OMIM:232400), which when mutated leads to glycogen storage disease, type III.
32	slt-1	F40E10.4	n/a	chrX 14,678,771	slt-1 encodes the sole C. elegans homolog of Drosophila Split, a secreted extracellular protein containing leucine-rich and EGF-like repeats that functions as a ligand for the Robo receptor; during C. elegans larval development, slt-1 acts via the SAX-3/Robo receptor, and in parallel with UNC-6/Netrin, to direct ventral axon guidance and guidance at the midline; during embryonic development, slt-1 also functions to regulate anterior-posterior migrations of the CAN neurons; slt-1::gfp reporters are initially expressed at high levels in the anterior part of the embryo, with more moderate levels seen in dorsal tail muscles and lower levels seen in cells in the center of the body; in L1 larvae, slt-1::gfp is expressed in both dorsal and ventral muscles, with higher levels seen in dorsal muscle cells; slt-1::gfp is also expressed in a number of additional cells including some neurons, pharyngeal cells, and the anal sphincter muscle.
33	cyp-14A4	R04D3.1	n/a	chrX 13,283,058	C. elegans CYP-14A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
34	F58H7.2	F58H7.2	n/a	chrIV 942,839	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR015830 (Amidase, fungi type)
35	M04F3.4	M04F3.4	n/a	chrI 4,772,433	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
36	K12H4.4	K12H4.4	n/a	chrIII 8,045,336	contains similarity to Pfam domain PF04573 Signal peptidase subunit contains similarity to Interpro domain IPR007653 (Signal peptidase 22 kDa subunit)
37	lam-1	W03F8.5	n/a	chrIV 5,176,291	lam-1 encodes a laminin beta that affects degenerin-induced cell death and is required redundantly with lam-2 for morphogenesis.
38	aha-1	C25A1.11	n/a	chrI 10,195,452	aha-1 encodes an ortholog of human aryl-hydrocarbon receptor nuclear translocator; interacts with AHR-1 and HIF-1 in vitro, requires HIF-1 for proper localization, and is expressed ubiquitously.
39	C01H6.2	C01H6.2	n/a	chrI 7,206,143	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
40	C14B9.3	C14B9.3	n/a	chrIII 8,109,908
41	F38A1.8	F38A1.8	n/a	chrIV 1,236,362	contains similarity to Pfam domains PF00448 (SRP54-type protein, GTPase domain) , PF02881 (SRP54-type protein, helical bundle domain) , PF04086 (Signal recognition particle, alpha subunit, N-terminal) contains similarity to Interpro domains IPR007222 (Signal recognition particle receptor, alpha subunit, N-terminal), IPR000897 (Signal recognition particle, SRP54 subunit, GTPase), IPR011012 (Longin-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR003593 (AAA+ ATPase, core)
42	Y45F10D.7	Y45F10D.7	n/a	chrIV 13,792,547	Y45F10D.7 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of human WDR36, mutations in which cause primary open angle glaucoma type 1G (GLC1G, OMIM:609887); large-scale RNAi experiments indicate that Y45F10D.7 activity is required for embryonic and larval development; the Saccharomyces cerevisiae homolog of WDR36, Utp21, is a component of the small-subunit (SSU) processome required for formation of 18S rRNA.
43	C28G1.2	C28G1.2	n/a	chrX 8,837,092	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
44	R03C1.1	R03C1.1	n/a	chrII 14,908,902	contains similarity to Homo sapiens Mucin-5AC precursor (Fragment); ENSEMBL:ENSP00000351148
45	pqn-66	T16A1.7	n/a	chrII 2,088,014	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
46	C30G12.4	C30G12.4	n/a	chrII 7,262,590	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
47	F01G12.6	F01G12.6	n/a	chrX 16,401,117	contains similarity to Drosophila melanogaster Flybase gene name is CG11727-PA;; FLYBASE:CG11727
48	C49A1.10	C49A1.10	n/a	chrI 14,243,227	contains similarity to Mus musculus Proteinase activated receptor 3 precursor (PAR-3) (Thrombin receptor-slike 2) (Coagulation factor II receptor-like 2).; SW:PAR3_MOUSE
49	D2045.9	D2045.9	n/a	chrIII 10,477,763	contains similarity to Pfam domain PF01755 Glycosyltransferase family 25 (LPS biosynthesis protein) contains similarity to Interpro domains IPR002654 (Glycosyl transferase, family 25), IPR000886 (Endoplasmic reticulum, targeting sequence)
50	W02B3.6	W02B3.6	n/a	chrIII 690,542	contains similarity to Pfam domain PF01744 GLTT repeat (6 copies) contains similarity to Interpro domain IPR008164 (Repeat of unknown function XGLTT)