UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K09D9.1	K09D9.1	1e-165	chrV 4,025,632
2	F08G2.5	F08G2.5	n/a	chrII 13,833,272	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
3	sul-2	D1014.1	n/a	chrV 8,158,775	sul-2 is orthologous to the human gene ARYLSULFATASE A (ARSA; OMIM:250100), which when mutated leads to metachromatic leukodystrophy.
4	R11D1.3	R11D1.3	n/a	chrV 12,711,700	contains similarity to Proteus mirabilis Hypothetical protein (Fragment).; TR:O86985
5	C49G7.10	C49G7.10	4e-43	chrV 4,041,191	contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
6	F41C6.6	F41C6.6	n/a	chrX 6,881,383
7	M04G7.1	M04G7.1	n/a	chrIV 456,400	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000877 (Proteinase inhibitor I12, Bowman-Birk), IPR003582 (Metridin-like ShK toxin)
8	E02C12.11	E02C12.11	n/a	chrV 9,379,644	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
9	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
10	ida-1	B0244.2	n/a	chrIII 5,760,627	ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles.
11	F53E10.4	F53E10.4	n/a	chrV 2,593,813
12	F43G9.5	F43G9.5	n/a	chrI 8,615,863	F43G9.5 encodes a NUDIX hydrolase that that inhibits DHC-1 in vivo, and is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; F43G9.5(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F43G9.5 negatively regulates dynein; while loss of F43G9.5 function has no obvious effect on lifespan, dauer formation, or fat storage, F43G9.5 is required for embryonic development, fertility, and general health in mass RNAi assays.
13	scl-25	T19C9.5	n/a	chrV 17,227,538	C. elegans SCL-25 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
14	K06A4.2	K06A4.2	n/a	chrV 9,487,363	contains similarity to Pfam domains PF00293 (NUDIX domain) , PF05026 (Dcp2, box A domain) contains similarity to Interpro domains IPR015797 (NUDIX), IPR007722 (Dcp2, box A), IPR000086 (NUDIX hydrolase, core)
15	F32B6.10	F32B6.10	n/a	chrIV 9,888,531	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
16	C39D10.2	C39D10.2	n/a	chrX 7,889,123
17	C01B4.8	C01B4.8	n/a	chrV 2,491,606	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
18	B0238.12	B0238.12	n/a	chrV 5,268,306	B0238.12 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; B0238.12 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; B0238.12 has no obvious function in mass RNAi assays.
19	B0228.8	B0228.8	n/a	chrII 7,760,555
20	Y43F8C.5	Y43F8C.5	n/a	chrV 19,631,978	contains similarity to Dictyostelium discoideum Myb-like protein (Fragment).; SW:MYBH_DICDI
21	ins-30	ZC334.2	n/a	chrI 14,035,617	ins-30 encodes an insulin-like peptide.
22	scl-3	F49E11.11	n/a	chrIV 13,060,112	C. elegans SCL-3 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
23	C01G10.4	C01G10.4	n/a	chrV 15,089,864	contains similarity to Staphylococcus aureus Staphylococcal secretory antigen ssaA2 precursor.; SW:Q5HDQ9
24	F44G4.6	F44G4.6	n/a	chrII 9,001,316	contains similarity to Interpro domain IPR001209 (Ribosomal protein S14)
25	C15C7.4	C15C7.4	n/a	chrX 3,146,822
26	F35H10.3	F35H10.3	n/a	chrIV 8,326,450
27	clec-108	Y26D4A.6	n/a	chrI 13,081,794	C. elegans CLEC-108 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	flp-13	F33D4.3	n/a	chrIV 7,697,747	C. elegans FLP-13 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
29	R102.1	R102.1	n/a	chrIV 10,686,816	contains similarity to Oryza sativa Similar to Arabidopsis thaliana chromosome 4.; TR:Q9LWR6
30	sol-1	C15A11.3	n/a	chrI 7,392,485	C. elegans SOL-1 protein; contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
31	pqn-60	R11G11.7	n/a	chrV 504,306	pqn-60 encodes a 154-residue, glutamine/asparagine (Q/N)-rich ('prion'-like) protein, predicted to have coiled-coil structure, with many paralogs in nematodes but no obvious non-nematode orthologs; PQN-60 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
32	tsp-1	C02F5.8	n/a	chrIII 8,238,638	C. elegans TSP-1 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013305 (ABC transporter, ABCB2), IPR003091 (Voltage-dependent potassium channel)
33	C49G7.5	C49G7.5	6e-33	chrV 4,042,984
34	hen-1	C36B7.7	n/a	chrX 7,116,551	hen-1 encodes a secreted protein that contains a low-density lipoprotein (LDL) receptor motif A; HEN-1 activity is required for integration of sensory stimuli and behavioral plasticity; a hen-1::GFP reporter is expressed in pharyngeal muscles, the vulva, and weakly in a subset of neurons; antibodies to HEN-1 protein detect expression exclusively in the AIY and ASE neurons, where HEN-1 appears to localize to cell bodies and in a punctate pattern in nerve ring axons at sites of synapse formation; HEN-1 expression in AIY appears to be under the control of the TTX-3 LIM domain transcription factor.
35	C25F9.8	C25F9.8	n/a	chrV 19,395,796	contains similarity to Nicotiana glutinosa Ribonuclease NW.; TR:Q7XZV5
36	T16G1.7	T16G1.7	n/a	chrV 12,933,975	T16G1.7 is orthologous to the human gene ALIAS DLC1~CANDIDATE TUMOR SUPPRESSOR GENE (DLEC1; OMIM:604050), which when mutated leads to disease.
37	C49G7.6	C49G7.6	n/a	chrV 4,041,399
38	dod-6	T20G5.7	n/a	chrIII 10,197,925	C. elegans DOD-6 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
39	F28A12.3	F28A12.3	n/a	chrV 8,641,003
40	ZC328.5	ZC328.5	n/a	chrI 6,406,411
41	aqp-3	Y69E1A.7	n/a	chrIV 10,962,555	aqp-3 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases water or glycerol permeability five- to seven-fold; loss of AQP-3 activity via mutation or RNAi results in no obvious defects; however, AQP-3, in conjunction with AQP-2, AQP-4, and AQP-8, is weakly required for recovery from hypotonic stress; AQP-3 is expressed in the intestine, excretory cell, seminal vesicle, and vas deferens.
42	K04H8.3	K04H8.3	n/a	chrI 14,256,314	contains similarity to Bacteroides thetaiotaomicron Putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismatesmutase.; TR:Q8A0T7
43	mec-9	C50H2.3	n/a	chrV 9,911,331	mec-9 encodes a predicted extracellular protein containing six EGF-like repeats,five Kunitz-type protease inhibitor domains, and a glutamic acid-rich region possibly involved in protein-protein interactions; mec-9 encodes two proteins, only one of which, MEC-9L, appears to be required for normal mechanosensory response to gentle touch and proper functioning of the touch receptor neurons; mec-9 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-9L is expressed and secreted by the touch receptor neurons.
44	cwp-2	C37H5.11	n/a	chrV 4,842,261	cwp-2 encodes a nematode-specific protein that is coexpressed with lov-1 and pkd-2.
45	clec-217	F26D11.9	n/a	chrV 7,958,038	C. elegans CLEC-217 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
46	C55A6.6	C55A6.6	n/a	chrV 11,514,222	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
47	C35B1.3	C35B1.3	n/a	chrIV 4,081,235
48	fbxa-99	F36G9.14	n/a	chrV 15,982,244	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
49	F39G3.4	F39G3.4	n/a	chrV 4,725,680	contains similarity to Pfam domain PF03188 Cytochrome b561 contains similarity to Interpro domains IPR004877 (Cytochrome b561), IPR006593 (Cytochrome b561 / ferric reductase transmembrane)
50	F07G11.7	F07G11.7	n/a	chrV 7,303,485	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)