UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	asp-5	F21F8.3	0	chrV 8,273,166	C. elegans ASP-5 protein; contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
4	cpr-1	C52E4.1	n/a	chrV 11,976,112	cpr-1 encodes a cysteine protease of the cathepsin B-like cysteine protease family; cpr-1 appears to be required for embryogenesis; cpr-1 is specifically expressed in the gut of all stages except the embryo and around developing embryos in the gonad; expression of cpr-1 is regulated by three promoter GATA motifs.
5	asp-6	F21F8.7	5e-148	chrV 8,268,253	aspartic protease.
6	cyp-35B1	K07C6.4	n/a	chrV 3,940,140	C. elegans CYP-35B1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
7	T10C6.7	T10C6.7	n/a	chrV 16,030,594	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
8	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
9	elo-1	F56H11.4	n/a	chrIV 9,527,335	elo-1 encodes a component of C-18 polyunsaturated fatty acid (PUFA) elongase that is required for normal elongation of n-6 and n-3 20-carbon PUFA in vivo; ELO-1 is a condensing enzyme that elongates n-6 and n-7 (and, with less efficiency, n-3) series C18 PUFAs.
10	mdh-1	F20H11.3	n/a	chrIII 6,607,404	mdh-1 encodes a homolog of malate dehydrogenase that is predicted to be mitochondrial.
11	C28H8.3	C28H8.3	n/a	chrIII 5,911,573	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) , PF04851 (Type III restriction enzyme, res subunit) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR008162 (Inorganic pyrophosphatase), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
12	C44C8.3	C44C8.3	n/a	chrIV 896,078	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
13	rpl-30	Y106G6H.3	n/a	chrI 10,436,561	rpl-30 encodes a large ribosomal subunit L30 protein; by homology, RPL-30 is predicted to function in protein biosynthesis; in C. elegans, loss of rpl-30 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities.
14	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
15	lys-6	F58B3.3	n/a	chrIV 11,627,398	C. elegans LYS-6 protein; contains similarity to Pfam domain PF01183 Glycosyl hydrolases family 25 contains similarity to Interpro domains IPR017853 (Glycoside hydrolase, catalytic core), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR002053 (Glycoside hydrolase, family 25)
16	W09D10.1	W09D10.1	n/a	chrIII 10,738,396	contains similarity to Pfam domain PF01412 Putative GTPase activating protein for Arf contains similarity to Interpro domain IPR001164 (Arf GTPase activating protein)
17	pas-2	D1054.2	n/a	chrV 10,770,774	pas-2 encodes a proteasome subunit with highest similarity to vertebrate proteasome alpha 2 subunits.
18	F58H7.8	F58H7.8	n/a	chrIV 908,458
19	C17H12.4	C17H12.4	n/a	chrIV 6,800,609	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
20	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	K05F1.10	K05F1.10	n/a	chrII 5,805,057	K05F1.10 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; K05F1.10 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; although it has no obvious function in mass RNAi assays, K05F1.10 transcription is reproducibly induced by infection, suggesting that it may participate in innate immunity.
22	C44C8.4	C44C8.4	n/a	chrIV 891,926	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
23	cyp-25A1	C36A4.1	n/a	chrIII 3,833,539	C. elegans CYP-25A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
24	fbxa-59	T12B5.8	n/a	chrIII 942,155	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
25	F45F2.10	F45F2.10	n/a	chrV 8,515,924	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
26	hpd-1	T21C12.2	n/a	chrIII 10,536,487	hpd-1 encodes a putative 4-hydroxyphenylpyruvate dioxygenase required for normally short lifespan and for negative regulation of the dauer larval stage, with loss of hpd-1 function prolonging lifespan and promoting dauer formation; hpd-1 is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; HPD-1 is orthologous to human HPD (OMIM:609695, mutated in tyrosinemia type III), and is paralogous to C31H2.4 and human HPDL/GLOXD1; HPD-1 is expressed in hypodermis and intestine, and is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
27	vpr-1	F33D11.11	n/a	chrI 5,869,119	C. elegans VPR-1 protein; contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein), IPR016763 (Vesicle-associated membrane protein)
28	ZK370.8	ZK370.8	n/a	chrIII 8,753,333	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013026 (Tetratricopeptide region)
29	T19D12.6	T19D12.6	n/a	chrII 6,640,052	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF02210 (Laminin G domain) (3), PF00054 (Laminin G domain) (2)contains similarity to Interpro domains IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR001791 (Laminin G), IPR006209 (EGF-like), IPR006210 (EGF), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR012680 (Laminin G, subdomain 2), IPR008985 (Concanavalin A-like lectin/glucanase), IPR012679 (Laminin G, subdomain 1)
30	gly-3	ZK688.8	n/a	chrIII 7,916,183	gly-3 encodes an N-acetylgalactosaminyltransferase that is functional in vitro.
31	ZK328.6	ZK328.6	n/a	chrIII 6,029,645	contains similarity to Pfam domains PF02818 (PPAK motif) , PF00646 (F-box domain) contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
32	rpn-7	F49C12.8	n/a	chrIV 9,317,349	rpn-7 is predicted to encode a non-ATPase subunit of the 19S regulatory complex of the proteasome that affects fertility and embryonic viability.
33	R05F9.12	R05F9.12	n/a	chrII 4,919,859	contains similarity to Pfam domains PF01055 (Glycosyl hydrolases family 31) , PF00088 (Trefoil (P-type) domain) contains similarity to Interpro domains IPR000519 (P-type trefoil), IPR017853 (Glycoside hydrolase, catalytic core), IPR000322 (Glycoside hydrolase, family 31)
34	fshr-1	C50H2.1	n/a	chrV 9,892,316	fshr-1 encodes a putative neuropeptide receptor required for normal acetylcholine secretion by synapses; FSHR-1 is orthologous to human follicle-stimulating hormone receptor (OMIM:136435; mutated in ovarian dysgenesis), thyrotropin receptor (OMIM:603372; mutated in hyperthyroidism), and luteinizing hormone receptor (OMIM:152790, mutated in precocious puberty); fshr-1 mutants have abnormally many GFP::SNB-1 puncta at synapses, suggesting exocytotic defects; the requirement for FSHR-1 and ten other predicted neuropeptide signalling proteins in cholinergic neurotransmission indicates that such signalling is important for regulating acetylcholine release at neuromuscular junctions; possible ligands of FSHR-1 are FLP-1 and NLP-12.
35	asp-3	H22K11.1	3e-38	chrX 6,791,899	asp-3 encodes an aspartyl protease homolog that is required, in parallel with ASP-4 but downstream of CLP-1 and TRA-3, for degenerative (necrotic-like) cell death in neurons induced by mutations such as mec-4(d), deg-3(d), or gsa-1(gf).
36	elo-5	F41H10.7	n/a	chrIV 5,375,925	The elo-5 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-5 is required for normally rapid growth and for normal fatty acid composition.
37	C44C8.1	C44C8.1	n/a	chrIV 904,383	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
38	F43G9.3	F43G9.3	n/a	chrI 8,613,923	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002167 (Graves disease carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
39	tag-314	F15H10.4	n/a	chrV 10,427,635	C. elegans TAG-314 protein; contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type)
40	ZK1058.9	ZK1058.9	n/a	chrIII 3,924,612	contains similarity to Borrelia burgdorferi Probable O-sialoglycoprotein endopeptidase (EC 3.4.24.57)s(Glycoprotease).; SW:GCP_BORBU
41	cogc-8	R02D3.2	n/a	chrIV 242,340	cogc-8 encodes an ortholog of mammalian COG-8, a subunit of lobe B of the conserved oligomeric Golgi complex (COGC); COGC-8 is weakly required for normal gonadal distal tip cell migration, a process that also requires seven other orthologs of COGC subunits; like other lobe B subunits in both C. elegans and S. cerevisiae, COGC-8 is only partially required for normal function, while lobe A subunits are strongly required in either worms or yeast.
42	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
43	dpf-5	R11E3.8	n/a	chrIV 4,804,689	dpf-5 encodes a putative acylamino-acid-releasing enzyme (AARE; EC 3.4.19.1), orthologous to human APEH, with no obvious function in mass RNAi assays.
44	R05F9.6	R05F9.6	n/a	chrII 4,890,420	contains similarity to Pfam domains PF02879 (Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II) , PF02878 (Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I) , PF02880 (Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III) , PF00408 (Phosphoglucomutase/phosphomannomutase, C-terminal domain) contains similarity to Interpro domains IPR016066 (Alpha-D-phosphohexomutase, conserved site), IPR005843 (Alpha-D-phosphohexomutase, C-terminal), IPR016055 (Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III), IPR005841 (Alpha-D-phosphohexomutase, N-terminal), IPR005844 (Alpha-D-phosphohexomutase, alpha/beta/alpha domain I), IPR005846 (Alpha-D-phosphohexomutase, alpha/beta/alpha domain III), IPR005845 (Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)
45	B0035.13	B0035.13	n/a	chrIV 11,305,691	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
46	R06B9.3	R06B9.3	n/a	chrII 13,759,726	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000694 (Proline-rich region), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
47	F43G9.1	F43G9.1	n/a	chrI 8,607,769	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004434 (Isocitrate dehydrogenase NAD-dependent, mitochondrial), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
48	F49H6.3	F49H6.3	n/a	chrV 17,015,023	contains similarity to Pfam domain PF06653 Protein of unknown function (DUF1164) contains similarity to Interpro domain IPR009545 (Protein of unknown function DUF1164)
49	clec-26	T20B3.12	n/a	chrV 16,849,392	C. elegans CLEC-26 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
50	btb-14	Y57A10B.3	n/a	chrII 12,383,995	C. elegans BTB-14 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)