UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	che-3	F18C12.1	0	chrI 8,071,859	The dynein heavy chain (DHC) 1b isoform that affects the establishment and maintainance of the structural integrity of sensory cilia and also has a role in intraflagellar transport; it is expressed in ciliated sensory neurons.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	bbs-5	R01H10.6	n/a	chrIII 10,260,159	C. elegans BBS-5 protein; contains similarity to Pfam domain PF07289 Protein of unknown function (DUF1448) contains similarity to Interpro domains IPR006606 (Protein of unknown function DUF1448), IPR008162 (Inorganic pyrophosphatase), IPR014003 (Protein of unknown function DM16)
4	C39B10.5	C39B10.5	n/a	chrX 10,447,468	contains similarity to Saccharomyces cerevisiae bZIP protein; transcription factor; SGD:YIR018W
5	Y44A6D.3	Y44A6D.3	n/a	chrV 20,786,983	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
6	let-23	ZK1067.1	n/a	chrII 9,202,659	let-23 encodes an EGF-receptor-family transmembrane tyrosine kinase that affects viability, inductive signaling during development of the vulva, male spicule formation, posterior development of the epidermis, ovulation and behavioral quiescience during lethargus; it is genetically upstream of the let-60/RAS pathway with respect to viability and vulval development, is upstream of phosopholipase C gamma with respect to fertility and quiesence, and is expressed in vulval precursor cells and the ALA neuron.
7	hum-4	F46C3.3	n/a	chrX 11,426,926	hum-4 encodes a class XII myosin, an unconventional myosin.
8	Y43C5A.4	Y43C5A.4	n/a	chrIV 10,278,717	contains similarity to Interpro domain IPR000694 (Proline-rich region)
9	C54E10.2	C54E10.2	n/a	chrV 18,829,031	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
10	F27E11.1	F27E11.1	n/a	chrV 3,464,980	contains similarity to Pfam domains PF01773 (Na+ dependent nucleoside transporter N-terminus) , PF07670 (Nucleoside recognition) , PF07662 (Na+ dependent nucleoside transporter C-terminus) contains similarity to Interpro domains IPR008276 (Concentrative nucleoside transporter), IPR002668 (Na+ dependent nucleoside transporter), IPR011657 (Na+ dependent nucleoside transporter, C-terminal), IPR011642 (Nucleoside recognition)
11	srh-129	F14F9.7	n/a	chrV 5,143,034	C. elegans SRH-129 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1), IPR001036 (Acriflavin resistance protein), IPR010916 (TonB box, conserved site)
12	ZK896.9	ZK896.9	n/a	chrIV 12,857,434	ZK896.9 encodes a putative transporter of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc), orthologous to human SLC35A3 (OMIM:605632) and paralogous to C03H5.2 and SRF-3; ZK896.9 has no obvious function in RNAi assays, but this could reflect genetic redundancy with its paralogs.
13	B0554.5	B0554.5	n/a	chrV 425,501	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR016196 (MFS general substrate transporter)
14	R07D5.2	R07D5.2	n/a	chrX 15,113,200	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008979 (Galactose-binding like)
15	ZK892.6	ZK892.6	n/a	chrII 9,979,541	contains similarity to Vibrio parahaemolyticus Hypothetical protein.; TR:Q87PB2
16	F53B7.2	F53B7.2	n/a	chrV 10,993,353	F53B7.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that F53B7.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
17	tni-4	W03F8.1	n/a	chrIV 5,205,854	tni-4 encodes one of the four elegans troponin I proteins; tni-4 is required for the normal development of the pharynx during embryonic development; TNI-4 interacts only with the pharyngeal troponin C; tni-4 is expressed exclusively in the pharyngeal muscles.
18	C04A11.1	C04A11.1	n/a	chrX 13,661,662	contains similarity to Sorghum bicolor Extensin precursor (Proline-rich glycoprotein).; SW:EXTN_SORBI
19	F46F3.3	F46F3.3	n/a	chrV 11,668,418	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86J27
20	ast-1	T08H4.3	n/a	chrII 4,131,358	ast-1 encodes a novel ETS-box transcription factor; AST-1 is required for the proper navigation of some interneuron axons to their targets, for differentiation of the ventral cord pioneer neuron AVG, and for pharyngeal morphogenesis; AST-1 is transiently expressed in many head neurons late in their differentiation and axon outgrowth, and in a few pharyngeal cells; AST-1 is at first nuclear, but then relocates to spots in cell bodies and even neuronal processes; hypomorphic ast-1 mutants have axons extending laterally, and crossing over from the right axon tract to the left axon bundle; null ast-1(hd92) mutants are inviable, failing to attach a working pharynx to their cuticle during development and then starving as L1 larvae; behaviorally, hypomorphic ast-1 animals are at least superficially normal, indicating that the ventral nerve cord can tolerate at least some miswiring; AST-1 regulates odr-2 expression, while ast-1 expression is itself regulated by lin-11.
21	ZK470.1	ZK470.1	n/a	chrX 4,166,695	contains similarity to Interpro domain IPR007248 (Mpv17/PMP22)
22	R10E11.5	R10E11.5	n/a	chrIII 9,787,703	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
23	C07C7.1	C07C7.1	n/a	chrIV 9,184,575	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_0790.; TR:Q98RD0
24	nhr-251	ZK488.4	n/a	chrV 601,466	C. elegans NHR-251 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
25	C32B5.5	C32B5.5	n/a	chrII 974,906	contains similarity to Pfam domain PF00646 F-box domain
26	F11A5.8	F11A5.8	n/a	chrV 16,208,396	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
27	abf-3	F54B8.5	n/a	chrV 15,817,602	abf-3 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-3 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
28	twk-23	F19D8.1	n/a	chrX 13,819,543	twk-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-23 in C. elegans development and/or behavior is not yet known, however TWK-23 may function redundantly with other TWK channels; TWK-23 is expressed in neurons, muscle, the posterior intestine, and diffusely in many other tissues.
29	Y57A10C.8	Y57A10C.8	n/a	chrII 12,428,881	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR002355 (Multicopper oxidase, copper-binding site)
30	irk-3	K04G11.5	n/a	chrX 14,356,108	C. elegans IRK-3 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
31	sru-3	C33A12.11	n/a	chrIV 9,497,224	C. elegans SRU-3 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
32	glb-8	C26C6.7	n/a	chrI 7,510,602	glb-8 encodes a globin with no obvious function in mass RNAi assays; glb-8 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-8 expression is downregulated in a daf-2(e1370) mutant background under normoxic conditions; glb-8 expression is lower in L3 larvae than in young adults or dauers.
33	ZK455.5	ZK455.5	n/a	chrX 11,325,637	contains similarity to Pfam domain PF01066 CDP-alcohol phosphatidyltransferase contains similarity to Interpro domains IPR014472 (Choline/ethanolaminephosphotransferase), IPR000462 (CDP-alcohol phosphatidyltransferase)
34	F22F1.2	F22F1.2	n/a	chrX 8,150,103	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
35	F53F1.1	F53F1.1	n/a	chrV 13,405,004	contains similarity to Pfam domains PF00169 (PH domain) , PF00069 (Protein kinase domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) (2)contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR001849 (Pleckstrin-like), IPR000719 (Protein kinase, core), IPR015727 (Protein kinase C mu-related), IPR011993 (Pleckstrin homology-type), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
36	C14A6.8	C14A6.8	n/a	chrV 18,170,317	contains similarity to Gallus gallus Cellular tumor antigen p53 (Tumor suppressor p53).; SW:P53_CHICK
37	F13B12.3	F13B12.3	n/a	chrIV 10,441,433	contains similarity to Tetraodon nigroviridis Chromosome 12 SCAF8721, whole genome shotgun sequence. (Fragment).; TR:Q4T6K3
38	srb-15	C48B6.5	n/a	chrI 6,899,186	C. elegans SRB-15 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
39	F25E2.3	F25E2.3	n/a	chrX 812,150	contains similarity to Pfam domain PF02551 Acyl-CoA thioesterase contains similarity to Interpro domain IPR003703 (Acyl-CoA thioesterase)
40	nhr-42	C33G8.6	n/a	chrV 6,999,694	C. elegans NHR-42 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	lev-8	C35C5.5	n/a	chrX 11,562,231	lev-8 encodes a novel nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8 group of nAChR subunits; LEV-8 activity is required for normal rates of pharyngeal pumping and for fully wild-type responses (increased egg laying and body wall muscle contraction) to the nAChR agonist and antihelmintic levamisole; expression of a LEV-8::GFP reporter construct begins at the L1 larval stage and is detected in neurons, body wall and uterine muscle cells, and socket cells of the IL and OL mechanosensory neurons; expression in body wall muscles is strongest in the anterior, consistent with increased levamisole resistance of head, or anterior, muscles seen in lev-8 mutant animals.
42	srh-179	ZK228.7	n/a	chrV 18,477,190	C. elegans SRH-179 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	T21E12.3	T21E12.3	n/a	chrI 4,403,989	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
44	R09D1.5	R09D1.5	n/a	chrII 9,448,892	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
45	srj-57	T03D3.14	n/a	chrV 2,854,982	C. elegans SRJ-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	daf-11	B0240.3	n/a	chrV 11,721,848	The daf-11 gene encodes a guanylate cyclase that affects dauer formation, chemotaxis, and axon formation; it is genetically upstream of daf-12 with respect to dauer larvae formation and is expressed in a subset of amphid neurons.
47	egl-38	C04G2.7	n/a	chrIV 10,108,695	The egl-38 gene encodes a Pax5 homolog.
48	R07A4.4	R07A4.4	n/a	chrX 10,753,200	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR008266 (Tyrosine protein kinase, active site)
49	F08G12.3	F08G12.3	n/a	chrX 11,301,106	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I5Q0
50	srh-69	T21B4.7	n/a	chrII 12,514,088	C. elegans SRH-69 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)