UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C43D7.7	C43D7.7	2e-52	chrV 19,319,210	contains similarity to Dictyostelium discoideum Filament-interacting protein.; TR:Q967Y0
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	clec-40	T20B3.13	n/a	chrV 16,840,047	C. elegans CLEC-40 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
4	srp-8	F20D6.3	n/a	chrV 8,184,913	srp-8 encodes a predicted serpin (serine protease inhibitor)
5	che-11	C27A7.4	n/a	chrV 12,147,469	che-11 encodes a large, unfamiliar protein with orthologs in vertebrates and arthropods (e.g., KIAA0590 and CG11838-PA) and in Chlamydomonas (IFT140), as well as distant similarity to OSM-1 and ZK520.1; che-11 is required for normal synthesis of sensory cilia (via intraflagellar transport) in sensory neurons, osmotic avoidance, and dauer formation.
6	F10B5.3	F10B5.3	n/a	chrII 8,148,546	contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR015880 (Zinc finger, C2H2-like), IPR011333 (BTB/POZ fold), IPR013089 (Kelch related), IPR007087 (Zinc finger, C2H2-type)
7	C25F9.5	C25F9.5	n/a	chrV 19,409,124	contains similarity to Pfam domain PF00176 SNF2 family N-terminal domain contains similarity to Interpro domain IPR000330 (SNF2-related)
8	srab-4	C33G8.5	n/a	chrV 7,004,969	C. elegans SRAB-4 protein ;
9	Y54E2A.8	Y54E2A.8	n/a	chrII 14,780,444	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
10	morc-1	ZC155.3	n/a	chrIII 5,205,271	C. elegans MORC-1 protein; contains similarity to Interpro domain IPR003594 (ATP-binding region, ATPase-like)
11	nhr-75	C49D10.6	n/a	chrII 3,867,513	C. elegans NHR-75 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
12	ZC15.5	ZC15.5	n/a	chrV 20,294,125	contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
13	btb-4	F59H6.12	n/a	chrII 2,032,856	C. elegans BTB-4 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
14	frm-9	F31B12.3	n/a	chrX 10,817,663	frm-9 encodes a B41/ERM (ezrin/radixin/moesin) domain containing protein.
15	bcmo-2	F53C3.12	n/a	chrII 3,909,661	C. elegans BCMO-2 protein; contains similarity to Pfam domain PF03055 Retinal pigment epithelial membrane protein contains similarity to Interpro domains IPR004294 (Carotenoid oxygenase), IPR015123 (Bcr-Abl oncoprotein oligomerisation)
16	math-23	C46F9.2	n/a	chrII 1,903,365	The C46F9.2 gene encodes a protein closely similar to C46F9.3, which has a meprin-associated Traf homology (MATH) domain and may be involved in apoptosis.
17	tre-5	C23H3.7	n/a	chrII 54,158	C. elegans TRE-5 protein; contains similarity to Pfam domain PF01204 Trehalase contains similarity to Interpro domains IPR001661 (Glycoside hydrolase, family 37), IPR008928 (Six-hairpin glycosidase-like)
18	F56D5.9	F56D5.9	n/a	chrIV 9,420,446	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
19	C34G6.1	C34G6.1	n/a	chrI 5,912,249	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
20	T12B3.4	T12B3.4	n/a	chrIV 7,386,993	contains similarity to Pfam domain PF03637 Mob1/phocein family contains similarity to Interpro domain IPR005301 (Mob1/phocein)
21	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
22	R12E2.2	R12E2.2	n/a	chrI 4,180,486	contains similarity to Pfam domain PF07738 Sad1 / UNC-like C-terminal contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR008979 (Galactose-binding like)
23	R09D1.10	R09D1.10	n/a	chrII 9,465,285	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
24	pme-2	E02H1.4	n/a	chrII 9,594,003	pme-2 encodes a poly(ADP-ribose) polymerase (PARP) orthologous to human PARP2 (OMIM:607725); PME-2 has a predicted C-terminal catalytic domain; PME-2 has PARP activity in vitro, which is blocked by mammalian PARP inhibitors; since these inhibitors also cause embryonic lethality in worms exposed to ionizing radiation, PME-1 is likely to be required in vivo for repairing broken DNA.
25	mgl-2	F45H11.4	n/a	chrI 10,387,757	mgl-2 encodes a Group I metabotropic glutamate receptor (OMIM:604473, 604102, loss-of-function mutations in mice are associated with defects in long-term potentiation); by homology, MGL-2 is predicted to function as a post-synaptic G protein-coupled receptor that, in response to glutamate binding, stimulates phospholipase C activity and increases neuronal excitation, and in mammalian tissue culture cells, glutamate stimulation of MGL-2 does result in increased phosphoinositide turnover; a mutation in mgl-2 indicates that it is required for normal head movements and tap reversal reflexes, while loss of mgl-2 activity via large-scale RNAi screens indicates that MGL-2 is also required for embryogenesis; a mgl-2::GFP reporter is expressed in interneurons.
26	C08H9.13	C08H9.13	n/a	chrII 9,870,236	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR003624 (Leukemia inhibitory factor), IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
27	ZK402.2	ZK402.2	n/a	chrX 1,403,926	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
28	cyp-13A1	T10B9.8	n/a	chrII 9,780,487	C. elegans CYP-13A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
29	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
30	twk-1	F21C3.1	n/a	chrI 7,270,700	C. elegans TWK-1 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
31	F25H5.7	F25H5.7	n/a	chrI 9,156,467	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
32	Y75B8A.25	Y75B8A.25	n/a	chrIII 12,278,010	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
33	sri-42	T10D4.9	n/a	chrII 3,141,931	C. elegans SRI-42 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	srh-27	W05H5.4	n/a	chrII 12,449,129	C. elegans SRH-27 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	lgc-12	R13A5.4	n/a	chrIII 7,563,273	C. elegans LGC-12 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
36	B0432.4	B0432.4	n/a	chrII 287,664	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR001993 (Mitochondrial substrate carrier), IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR002113 (Adenine nucleotide translocator 1)
37	F31E9.3	F31E9.3	n/a	chrV 17,323,648	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
38	ZK1053.6	ZK1053.6	n/a	chrI 13,239,621	ZK1053.6 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK1053.6 is predicted to transport Mg(2+) into cells; ZK1053.6 is paralogous to K07H8.2 and ZK185.2, and has no obvious function in mass RNAi assays.
39	osm-7	T05D4.4	n/a	chrIII 13,578,274	C. elegans OSM-7 protein ;
40	sru-30	C50C10.3	n/a	chrV 9,814,394	C. elegans SRU-30 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
41	F58G1.8	F58G1.8	n/a	chrII 12,925,362	contains similarity to Interpro domain IPR009022 (Elongation factor G, III and V)
42	T20D4.12	T20D4.12	n/a	chrV 3,397,421	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
43	Y51A2D.8	Y51A2D.8	n/a	chrV 18,551,910	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
44	T25F10.1	T25F10.1	n/a	chrV 6,768,591
45	C46E1.1	C46E1.1	n/a	chrX 15,469,830	contains similarity to Staphylococcus aureus Surface protein SasB (Fragment).; TR:Q84GB4
46	str-77	W06D12.4	n/a	chrV 17,720,087	C. elegans STR-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	F36D4.6	F36D4.6	n/a	chrV 9,427,160
48	clec-29	T25E12.9	n/a	chrV 16,738,407	C. elegans CLEC-29 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
49	trxr-1	C06G3.7	n/a	chrIV 7,014,256	C06G3.7 encodes an homolog of the mammalian thioredoxin reductase isozymes TR1 and TR2; like its mammalian homologs, C06G3.7 has a TGA-encoded C-terminal penultimate selenocysteine (Sec) residue; labelling of C. elegans with selenium-75 demonstrates that TR-Se is the major naturally occurring selenoprotein in C. elegans, and computational analysis indicates that it is probably the only selenoprotein encoded by the genome; the 3'-untranslated region of this gene contains a selenocysteine insertion sequence that is functional in mammalian cell culture; by phylogenetic profiling, C06G3.7 protein is predicted to be mitochondrial.
50	C33H5.16	C33H5.16	n/a	chrIV 7,802,511	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)