UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	elo-4	C40H1.4	2.0000000000000002e-159	chrIII 9,333,203	The elo-4 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; its function in vivo is unknown.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
4	F23C8.7	F23C8.7	n/a	chrI 2,423,740	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
5	H41C03.1	H41C03.1	n/a	chrII 5,855,713	contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
6	tag-196	F41E6.6	n/a	chrV 8,596,111	C. elegans TAG-196 protein; contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) , PF00031 (Cystatin domain) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000010 (Proteinase inhibitor I25, cystatin), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
7	K12H6.9	K12H6.9	n/a	chrII 2,824,679
8	T09A12.1	T09A12.1	n/a	chrIV 8,245,495	contains similarity to Xenopus laevis DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).; SW:P41512
9	F57H12.5	F57H12.5	n/a	chrIV 7,968,487	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
10	C10G11.1	C10G11.1	n/a	chrI 6,307,930
11	R09E10.2	R09E10.2	n/a	chrIV 10,317,896	contains similarity to Pfam domain PF00102 (Protein-tyrosine phosphatase)
12	ZC328.5	ZC328.5	n/a	chrI 6,406,411
13	sulp-6	W01B11.2	n/a	chrI 3,290,255	sulp-6 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-6 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-6::GFP transcriptional fusion is expressed in the posterior intestine.
14	Y116A8C.37	Y116A8C.37	n/a	chrIV 17,130,526	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
15	snb-5	C30A5.5	n/a	chrIII 8,204,022	snb-5 encodes a predicted synaptobrevin.
16	Y66A7A.4	Y66A7A.4	n/a	chrIII 11,614,038
17	R148.7	R148.7	n/a	chrIII 3,196,950
18	R13A5.11	R13A5.11	n/a	chrIII 7,592,386	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
19	tag-329	C50F4.3	n/a	chrV 9,535,638	C. elegans TAG-329 protein; contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
20	T08H10.4	T08H10.4	n/a	chrV 4,480,975	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
21	F20D6.1	F20D6.1	n/a	chrV 8,191,303	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
22	F32B6.10	F32B6.10	n/a	chrIV 9,888,531	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
23	F35H10.3	F35H10.3	n/a	chrIV 8,326,450
24	F17E9.3	F17E9.3	n/a	chrIV 8,355,135
25	C35A5.4	C35A5.4	n/a	chrV 10,498,176	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000694 (Proline-rich region), IPR000535 (Major sperm protein)
26	F45E1.3	F45E1.3	n/a	chrX 7,987,677	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domain IPR005834 (Haloacid dehalogenase-like hydrolase)
27	ZK354.9	ZK354.9	n/a	chrIV 5,307,602	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
28	F36A4.1	F36A4.1	n/a	chrIV 4,272,674	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
29	T19D2.3	T19D2.3	n/a	chrX 3,939,726
30	C09G5.7	C09G5.7	n/a	chrII 10,715,547	contains similarity to Homo sapiens Putative uncharacterized protein (Fragment); ENSEMBL:ENSP00000333119
31	F36G9.15	F36G9.15	n/a	chrV 15,987,734	contains similarity to Pfam domain PF06678 Protein of unknown function (DUF1179) contains similarity to Interpro domain IPR009564 (Protein of unknown function DUF1179)
32	F52E4.5	F52E4.5	n/a	chrX 3,086,609
33	M195.4	M195.4	n/a	chrII 8,376,915	contains similarity to Homo sapiens Putative uncharacterized protein (Fragment); ENSEMBL:ENSP00000333119
34	W04A4.3	W04A4.3	n/a	chrI 13,680,877	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
35	sma-2	ZK370.2	n/a	chrIII 8,753,327	sma-2 encodes, along with sma-3 and sma-4, one of three C. elegans Smad proteins, with SMA-2 and SMA-3 most closely related to receptor-regulated Smads (R-Smads) and SMA-4 more closely related to co-mediator Smads (CoSmads); during development, SMA-2 functions in a TGF-beta signaling pathway to regulate body size and specification of sensory structures in the male tail; a sma-2::gfp reporter is expressed in the pharynx, intestine, and hypodermis.
36	F21F8.5	F21F8.5	n/a	chrV 8,265,454
37	Y23H5A.4	Y23H5A.4	n/a	chrI 2,618,955	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
38	B0228.8	B0228.8	n/a	chrII 7,760,555
39	Y45F10B.3	Y45F10B.3	n/a	chrIV 13,593,732	contains similarity to Saccharomyces cerevisiae N-terminal domain appears to be involved in cellular responsiveness to RAS.; SGD:YNL138W
40	C47E12.10	C47E12.10	n/a	chrIV 9,973,388	contains similarity to Pfam domain PF03057 Protein of unknown function contains similarity to Interpro domain IPR004296 (Protein of unknown function DUF236)
41	klp-17	W02B12.7	n/a	chrII 11,466,706	klp-17 encodes a C-terminal kinesin motor protein orthologous to Drosophila NCD and Saccharomyces cerevisiae KAR3; by homology, KLP-17 is predicted to function as a minus-end directed motor; loss of klp-17 activity via RNAi results in embryonic lethality generally at the one- or two-cell stage with disorganized mitotic spindles and polyploid nuclei, suggesting that KLP-17 plays a role in chromosome segregation and germline development; in situ hybridization studies reveal that klp-17 mRNA is localized specifically to cell nuclei during early development, from the one-cell stage of embryogenesis until early larval stages; a klp-17::gfp transgene did not yield detectable GFP expression, but did result in a small percentage of morphologically abnormal males and intersexual animals that grew slowly and died upon reaching maturity, consistent with a role for klp-17 in chromosome dynamics.
42	W03D8.1	W03D8.1	n/a	chrI 2,789,083	contains similarity to Cryptosporidium hominis Putative uncharacterized protein.; TR:Q5CFZ6
43	clec-124	C17F4.1	n/a	chrII 3,250,580	C. elegans CLEC-124 protein; contains similarity to Interpro domain IPR016187 (C-type lectin fold)
44	Y116A8C.38	Y116A8C.38	n/a	chrIV 17,132,537	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
45	K05F1.1	K05F1.1	n/a	chrII 5,802,499	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domain IPR002593 (Protein of unknown function DX)
46	F14D7.8	F14D7.8	n/a	chrV 14,312,353	contains similarity to Staphylococcus epidermidis Conserved hypothetical protein.; TR:Q8CSE5
47	C34B2.3	C34B2.3	n/a	chrI 10,673,805	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase)
48	F02C9.1	F02C9.1	n/a	chrV 3,138,918
49	ZK688.4	ZK688.4	n/a	chrIII 7,895,076
50	clec-236	Y70C5C.5	n/a	chrV 16,720,176	C. elegans CLEC-236 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)