UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C18H9.6	C18H9.6	1e-119	chrII 6,701,053
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	mup-2	T22E5.5	n/a	chrX 6,409,410	mup-2 encodes the muscle contractile protein troponin T ( TnT ) homologous to vertebrate and invertebrate TnT and contains an invertebrate- specific COOH -terminal tail; mup-2 affects embryonic body wall muscle cell contraction, sarcomere organization, cell positioning, regulated muscle contraction in larval and adult body wall muscle, epidermal morphogenesis, and is required for proper function of the hermaphrodite nonstriated oviduct myoepithelial sheath, proper growth, and fertility.
4	F54F11.2	F54F11.2	n/a	chrII 13,512,057	F54F11.2 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F54F11.2 has no clear orthologs in other organisms.
5	Y40D12A.2	Y40D12A.2	n/a	chrIII 6,613,768	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
6	C14C6.5	C14C6.5	n/a	chrV 537,024	contains similarity to Pfam domains PF04942 (CC domain) , PF01549 (ShK domain-like) (2)contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
7	F57F4.4	F57F4.4	n/a	chrV 6,405,140	contains similarity to Pfam domain PF01684 ET module contains similarity to Interpro domains IPR002603 (Protein of unknown function ET), IPR016054 (Ly-6 antigen / uPA receptor -like)
8	gfi-1	F57F4.3	n/a	chrV 6,396,213	gfi-1 encodes a protein that contains 21 ET modules; interacts with unc-68 in yeast two-hybrid assays.
9	F55G11.2	F55G11.2	n/a	chrIV 12,968,338	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
10	clec-52	B0218.8	n/a	chrIV 8,167,950	C. elegans CLEC-52 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR003990 (Pancreatitis-associated protein), IPR001304 (C-type lectin), IPR002352 (Eosinophil major basic protein)
11	ugt-13	H23N18.1	n/a	chrV 4,910,117	C. elegans UGT-13 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
12	T25C12.3	T25C12.3	n/a	chrX 11,495,472	contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR011162 (MHC classes I and II-like antigen recognition), IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans), IPR002035 (von Willebrand factor, type A)
13	VC5.1	VC5.1	n/a	chrV 7,102,942
14	F15E11.12	F15E11.12	n/a	chrV 2,326,970
15	F55G11.4	F55G11.4	n/a	chrIV 12,974,582	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
16	spl-1	Y66H1B.4	n/a	chrIV 381,542	C. elegans SPL-1 protein; contains similarity to Pfam domains PF00282 (Pyridoxal-dependent decarboxylase conserved domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
17	ugt-46	B0310.5	n/a	chrX 528,055	C. elegans UGT-46 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
18	F59A2.3	F59A2.3	n/a	chrIII 3,397,005	contains similarity to Pfam domain PF02330 Mitochondrial glycoprotein contains similarity to Interpro domain IPR003428 (Mitochondrial glycoprotein)
19	dod-19	ZK6.10	n/a	chrV 413,272	C. elegans DOD-19 protein; contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
20	ZK1025.8	ZK1025.8	n/a	chrI 11,470,513	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
21	F09B12.3	F09B12.3	n/a	chrX 15,096,564	contains similarity to Pfam domain PF04916 Phospholipase B contains similarity to Interpro domain IPR007000 (Laminin A)
22	gst-5	R03D7.6	n/a	chrII 10,950,899	gst-5 encodes a putative glutathione-S-transferase that inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
23	col-145	B0222.7	n/a	chrV 9,162,502	C. elegans COL-145 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3), PF07054 (Pericardin like repeat) contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
24	phat-3	C49G7.4	n/a	chrV 4,044,418	C. elegans PHAT-3 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
25	K07C5.4	K07C5.4	n/a	chrV 10,351,696	contains similarity to Pfam domains PF01798 (Putative snoRNA binding domain) , PF08060 (NOSIC (NUC001) domain) , PF08156 (NOP5NT (NUC127) domain) contains similarity to Interpro domains IPR012974 (NOP5, N-terminal), IPR005819 (Histone H5), IPR002687 (Pre-mRNA processing ribonucleoprotein, binding region), IPR012976 (NOSIC)
26	apy-1	F08C6.6	n/a	chrX 7,568,879	C. elegans APY-1 protein; contains similarity to Pfam domain PF06079 Apyrase contains similarity to Interpro domain IPR009283 (Apyrase)
27	ugt-8	H23N18.3	n/a	chrV 4,904,931	C. elegans UGT-8 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
28	act-5	T25C8.2	n/a	chrIII 13,605,190	an ortholog of human cytoplasmic actin; and is expressed only in microvillous intestinal cells and excretory cell.
29	C15C8.3	C15C8.3	n/a	chrV 12,743,084	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
30	W04G3.5	W04G3.5	n/a	chrX 11,074,823	contains similarity to Pfam domain PF00156 Phosphoribosyl transferase domain contains similarity to Interpro domains IPR005946 (Phosphoribosyl pyrophosphokinase), IPR000836 (Phosphoribosyltransferase)
31	C05G5.4	C05G5.4	n/a	chrX 14,755,163	contains similarity to Pfam domains PF00549 (CoA-ligase) , PF02629 (CoA binding domain) contains similarity to Interpro domains IPR005811 (ATP-citrate lyase/succinyl-CoA ligase), IPR005810 (Succinyl-CoA ligase, alpha subunit), IPR016040 (NAD(P)-binding), IPR017440 (ATP-citrate lyase/succinyl-CoA ligase, active site), IPR003781 (CoA-binding), IPR016102 (Succinyl-CoA synthetase-like)
32	C16C10.11	C16C10.11	n/a	chrIII 4,152,344	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domains IPR010625 (CHCH), IPR000104 (Antifreeze protein, type I), IPR000694 (Proline-rich region)
33	clec-49	W04E12.6	n/a	chrV 19,745,488	C. elegans CLEC-49 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
34	T25B6.2	T25B6.2	n/a	chrX 9,036,480	T25B6.2 encodes two isoforms of a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T25B6.2 is orthologous to Ac-mep-1, a gut luminal neprilysin which is specifically expressed in the adult life stage of Ancylostoma caninum hookworms, and whose protein product is localized to the microvilli of the gastrointestinal tract, suggesting a role in digestion.
35	unc-27	ZK721.2	n/a	chrX 8,789,978	unc-27 encodes a troponin I isoform; unc-27 is required for coordinated motility and normal muscle morphology; structural analyses indicate that unc-27 is required for proper sarcomeric organization; unc-27/troponin I interacts with the body wall and pharynx types of troponin C; expression studies show that unc-27 is expressed in body wall, vulval and anal muscles.
36	fbxa-72	F31F4.15	n/a	chrV 675,834	C. elegans FBXA-72 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
37	F15E11.1	F15E11.1	n/a	chrV 2,329,667	F15E11.1, along with F15E11.14, encodes a 17.4 kDa protein (CE16999) with unknown function that is seven-fold more abundant in glp-1 mutant hermaphrodites (which lack a germline) than in normal hermaphrodites; F15E11.1(RNAi) animals have no obvious mutant phenotype (i.e., they have no obvious defect in fertility or germline maintenance); the F15E11.1/14 protein belongs to a nematode-specific family including the paralogs F15E11.12, F15E11.13, F15E11.15, and Y19D10B.7.
38	lon-3	ZK836.1	n/a	chrV 12,198,007	lon-3 encodes a cuticle collagen; during development, lon-3 acts downstream of the TGF-beta signaling pathway to specify body length; lon-3 reporter fusions are expressed in hypodermal cells and LON-3 appears to localize to the surface of the animal, consistent with a role in cuticle formation.
39	Y76A2B.3	Y76A2B.3	n/a	chrIII 13,541,717	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
40	C44E4.4	C44E4.4	n/a	chrI 4,634,862	contains similarity to Pfam domains PF05383 (La domain) , PF08777 (RNA binding motif) , PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) contains similarity to Interpro domains IPR002344 (Lupus La protein), IPR014886 (RNA binding motif), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR011991 (Winged helix repressor DNA-binding), IPR006630 (RNA-binding protein Lupus La), IPR000504 (RNA recognition motif, RNP-1)
41	F36H1.5	F36H1.5	n/a	chrIV 11,030,632	contains similarity to Agrobacterium tumefaciens Hypothetical protein Atu4002.; TR:Q8U8T6
42	R07H5.8	R07H5.8	n/a	chrIV 11,210,138	contains similarity to Pfam domain PF00294 pfkB family carbohydrate kinase contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR002139 (Ribokinase), IPR001805 (Adenosine kinase), IPR002173 (Carbohydrate/puine kinase, PfkB, conserved site)
43	lec-10	W01A11.4	n/a	chrV 6,488,658	lec-10 encodes a galectin, a soluble galactose-binding lectin; recombinant lec-10 can bind to sugar in an in vitro assay.
44	ZK1025.2	ZK1025.2	n/a	chrI 11,450,904	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
45	T16G1.6	T16G1.6	n/a	chrV 12,936,341	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
46	col-180	C44C10.1	n/a	chrX 11,711,753	C. elegans COL-180 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
47	F35D11.4	F35D11.4	n/a	chrII 4,603,738	contains similarity to Pfam domain PF01928 CYTH domain contains similarity to Interpro domains IPR008172 (Adenylate cyclase), IPR008173 (Adenylyl cyclase CyaB)
48	hsp-1	F26D10.3	n/a	chrIV 17,280,029	hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity.
49	tfg-1	Y63D3A.5	n/a	chrI 14,103,115	C. elegans TFG-1 protein; contains similarity to Pfam domain PF00564 PB1 domain contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region), IPR000270 (Octicosapeptide/Phox/Bem1p)
50	Y49A3A.1	Y49A3A.1	n/a	chrV 14,349,107	Y49A3A.1 encodes a homolog of choline/ethanolaminephosphotransferase choline phosphotransferase 1; Y49A3A.1 shares an operon with vha-13, and thus might be a previously undescribed V-ATPase component or ancillary protein.