UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clpp-1	ZK970.2	9e-115	chrII 10,301,745	clpp-1 encodes a mitochondrial protein, homologous to bacterial ClpP, required to initiate the stress response to unfolded mitochondrial proteins; as with its bacterial ortholog, CLPP-1 is predicted to be a proteolytic subunit of a Clp-like protease, with an N-terminal region required for mitochondrial localization, and a C-terminal region of ClpP similarity; in response to a mutation stressing mitochondria, clpp-1(RNAi) animals show reduced HSP-60 levels, inhibited nuclear translocation and hsp-60 activation by DVE-1, and aberrant mitochondrial morphology; CLPP-1 is biochemically inhibited by the ClpP inhibitor Z-LY-CMK and the peptide aldehyde MG132, and may also be blocked by them when injected in vivo; CLPP-1 is expressed in the intestine.
2	aat-1	F27C8.1	n/a	chrIV 9,600,317	aat-1 encodes an amino acid transporter catalytic subunit; when co-expressed in Xenopus oocytes with the ATG-2 glycoprotein subunit, AAT-1 is able to facilitate amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; in addition, AAT-1 is able to covalently associate with ATG-2 or ATG-1 to form heterodimers in the Xenopus expression system; when co-expressed with ATG-2, AAT-1 localizes to the cell surface of oocytes, but when expressed alone or with ATG-1, AAT-1 localizes intracellularly.
3	E04A4.3	E04A4.3	n/a	chrIV 4,730,919
4	ocr-2	T09A12.3	n/a	chrIV 8,216,912	ocr-2 encodes a TRPV (transient receptor potential channel, vanilloid subfamily) ion channel; OCR-2 activity is required for several types of sensory transduction including olfaction, osmosensation, mechanosensation, and chemosensation; an OCR-2 fusion protein is expressed in sensory cilia and requires the OSM-9 TRPV channel protein for proper localization; likewise, OSM-9 requires OCR-2 for its cilial localization.
5	ceh-34	C10G8.6	n/a	chrV 5,317,530	ceh-34 encodes a homeodomain protein, homologous to human SIX2 (OMIM:604994), that is expressed very weakly in the pharynxes of late embryos and early larvae; it has no known function.
6	srh-223	F47C12.3	n/a	chrIV 3,982,749	C. elegans SRH-223 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	math-32	F59H6.4	n/a	chrII 2,012,019	C. elegans MATH-32 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
8	F54F3.3	F54F3.3	n/a	chrV 12,920,812	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1), IPR008262 (Lipase, active site)
9	fbxa-220	Y66A7A.1	n/a	chrIII 11,483,373	C. elegans FBXA-220 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
10	Y37A1B.6	Y37A1B.6	n/a	chrIV 14,038,988	contains similarity to Bacillus amyloliquefaciens Beta-glucanase (BglA) (Fragment).; TR:Q44651
11	nhr-132	R11G11.1	n/a	chrV 535,310	C. elegans NHR-132 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
12	C54E4.4	C54E4.4	n/a	chrIV 2,163,172
13	F53A3.1	F53A3.1	n/a	chrIII 1,941,574
14	sri-28	B0454.3	n/a	chrII 3,049,551	C. elegans SRI-28 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	srw-138	C44C3.3	n/a	chrV 2,962,370	C. elegans SRW-138 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
16	F59C6.8	F59C6.8	n/a	chrI 10,511,155	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
17	nhr-70	Y51A2D.17	n/a	chrV 18,618,286	C. elegans NHR-70 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR002232 (5-Hydroxytryptamine 6 receptor)
18	srbc-2	C04E12.9	n/a	chrV 3,375,717	C. elegans SRBC-2 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
19	R07B1.6	R07B1.6	n/a	chrX 9,867,228	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
20	skr-19	R12H7.3	n/a	chrX 13,224,084	The skr-19 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-19(RNAi) animals are at least superficially normal.
21	Y51A2B.5	Y51A2B.5	n/a	chrV 18,390,243	contains similarity to Interpro domain IPR014044 (SCP-like extracellular)
22	srz-61	K03D3.4	n/a	chrIV 16,322,140	C. elegans SRZ-61 protein ;
23	W04B5.6	W04B5.6	n/a	chrIII 2,434,376
24	inx-20	T23H4.1	n/a	chrI 9,877,813	C. elegans INX-20 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
25	ptr-19	Y39A1B.2	n/a	chrIII 10,786,410	ptr-19 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-19 is required for normal development in mass RNAi assays; PTR-19 is expressed in pharynx, hypodermis, nervous system (including head neurons), and other cells.
26	C29F9.1	C29F9.1	n/a	chrIII 133,396
27	nhr-266	F56H1.2	n/a	chrI 5,738,931	C. elegans NHR-266 protein; contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR003125 (Protein of unknown function WSN)
28	F23C8.3	F23C8.3	n/a	chrI 2,440,875
29	R05C11.1	R05C11.1	n/a	chrIV 2,070,210	contains similarity to Interpro domain IPR014756 (Immunoglobulin E-set)
30	R05A10.8	R05A10.8	n/a	chrIV 14,156,627	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
31	unc-130	C47G2.2	n/a	chrII 11,282,880	A member of the forkhead domain family of transcription factors that affects the generation of the AWA and ASG chemosensory neurons and is partially required for male tail morphogenesis and embryogenesis; it is expressed in the AWA and ASG precursors; it is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor.
32	srab-10	C36C5.7	n/a	chrV 3,143,828	C. elegans SRAB-10 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
33	F01G10.7	F01G10.7	n/a	chrIV 10,240,539	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1), IPR008262 (Lipase, active site)
34	che-13	F59C6.7	n/a	chrI 10,511,288	che-13 encodes a novel protein homologous to mammalian IFT57/Hippi (OMIM:606621, protein interactor of Huntingtin-interacting protein 1 that is implicated in neuronal apoptosis in the Huntington disease state); CHE-13 is a proposed component of the intraflagellar transport (IFT) complex B, and is required for the construction and maintenance of cilia on a subset of sensory neurons; in addition, CHE-13 is required for proper localization of OSM-5, a murine polaris homolog, to IFT complex B; CHE-13 is expressed in ciliated sensory neurons including the amphids, phasmids, inner and outer labial neurons, and sensory rays of the male tail, localizing to the cilia base (transition zone) as well as to the axoneme; che-13 expression, like that of ciliogenic genes osm-1, osm-5, osm-6, and che-2, is positively regulated by the DAF-19 RFX-type transcription factor.
35	F56C9.8	F56C9.8	n/a	chrIII 7,317,655
36	K12C11.3	K12C11.3	n/a	chrI 1,336,076	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
37	src-2	F49B2.5	n/a	chrI 14,325,568	C. elegans SRC-2 protein; contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00018 (SH3 domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR000719 (Protein kinase, core), IPR013315 (Spectrin alpha chain), IPR011511 (Variant SH3), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
38	ZK688.7	ZK688.7	n/a	chrIII 7,911,165
39	frm-3	H05G16.1	n/a	chrX 11,578,915	frm-3 encodes a protein containing a FERM domain (Band 4.1 family); expressed in a few cells in the head.
40	Y37D8A.22	Y37D8A.22	n/a	chrIII 12,937,773	contains similarity to Danio rerio Transmembrane protein 49.; SW:Q6NYY9
41	cyp-34A10	B0213.16	n/a	chrV 3,971,866	C. elegans CYP-34A10 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
42	K04A8.5	K04A8.5	n/a	chrV 6,550,991	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1)
43	Y81G3A.3	Y81G3A.3	n/a	chrII 13,087,735	contains similarity to Pfam domains PF05773 (RWD domain) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR006575 (RWD), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000276 (GPCR, rhodopsin-like)
44	Y51A2A.6	Y51A2A.6	n/a	chrV 18,303,075	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
45	acr-12	R01E6.4	n/a	chrX 13,534,608	acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters.
46	str-148	M01D1.1	n/a	chrII 1,047,396	C. elegans STR-148 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
47	T16A1.5	T16A1.5	n/a	chrII 2,083,711
48	srd-60	C13B7.3	n/a	chrV 2,420,332	C. elegans SRD-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	F25H2.2	F25H2.2	n/a	chrI 10,544,713	contains similarity to Pfam domains PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00787 (PX domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR001683 (Phox-like), IPR001478 (PDZ/DHR/GLGF)
50	qui-1	Y45F10B.10	n/a	chrIV 13,568,114	The qui-1 gene encodes a protein of unknown function that contains several WD-40 domains.