UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nspa-5	ZC412.6	0.0000000000005	chrV 14,878,391	C. elegans NSPA-5 protein ;
2	nspa-3	ZC412.7	0.000000000002	chrV 14,880,465	C. elegans NSPA-3 protein ;
3	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	nspa-8	W06A7.5	0.000000000005	chrV 14,826,947	C. elegans NSPA-8 protein ;
6	nspa-1	H12D21.1	0.000000000002	chrV 14,886,813	C. elegans NSPA-1 protein ;
7	F37A8.1	F37A8.1	n/a	chrIII 3,928,769	contains similarity to Rattus norvegicus Myotonic dystrophy kinase-related Cdc42-binding kinase MRCK-beta.; TR:O54875
8	T25B9.6	T25B9.6	n/a	chrIV 10,759,435	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
9	clec-79	F47C12.4	n/a	chrIV 3,974,525	C. elegans CLEC-79 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR000538 (Link), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	gst-9	R05F9.5	n/a	chrII 4,892,523	gst-9 encodes a predicted glutathione S-transferase; by homology, GST-9 is predicted to play a role in the detoxification of environmental toxins and xenobiotics by transferring glutathione to reactive electrophilic compounds; however, as loss of gst-9 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GST-9 in C. elegans development and/or behavior is not yet known.
11	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
12	nspa-9	C40H5.1	0.00000000009	chrX 11,739,026	C. elegans NSPA-9 protein ;
13	F20D6.10	F20D6.10	n/a	chrV 8,193,961	contains similarity to Homo sapiens Protein FAM133A; ENSEMBL:ENSP00000318974
14	msp-74	F09C12.7	n/a	chrII 5,115,201	msp-74 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
15	F35H8.1	F35H8.1	n/a	chrII 9,552,878	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILJ6
16	W03D8.9	W03D8.9	n/a	chrI 2,785,349	contains similarity to Pfam domain PF05884 Caenorhabditis elegans protein of unknown function (DUF856) contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR008574 (Protein of unknown function DUF856, Caenorhabditis species)
17	nspd-4	T23B7.1	n/a	chrII 4,842,734	C. elegans NSPD-4 protein; contains similarity to Pfam domain PF05611 Caenorhabditis elegans protein of unknown function (DUF780) contains similarity to Interpro domain IPR008498 (Protein of unknown function DUF780, Caenorhabditis species)
18	B0273.1	B0273.1	n/a	chrIV 5,494,609
19	F36A4.4	F36A4.4	n/a	chrIV 4,267,908	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
20	W09C3.7	W09C3.7	n/a	chrI 4,714,903
21	F23C8.7	F23C8.7	n/a	chrI 2,423,740	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
22	R13H9.5	R13H9.5	n/a	chrIV 5,066,321	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
23	F36A4.2	F36A4.2	n/a	chrIV 4,271,510	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
24	ZK354.7	ZK354.7	n/a	chrIV 5,302,598	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein), IPR000533 (Tropomyosin)
25	W02D7.4	W02D7.4	n/a	chrV 8,297,041	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
26	T08B2.12	T08B2.12	n/a	chrI 6,231,810	contains similarity to Equine herpesvirus 1 Glycoprotein X precursor.; SW:Q6S6W0
27	C10G11.1	C10G11.1	n/a	chrI 6,307,930
28	C41G7.6	C41G7.6	n/a	chrI 9,526,981	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_96, whole genome shotgun sequence.; TR:A0EH68
29	F35H10.2	F35H10.2	n/a	chrIV 8,329,510
30	ins-7	ZK1251.2	n/a	chrIV 9,682,219	ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.
31	ssp-9	E03H12.10	n/a	chrIV 4,994,521	C. elegans SSP-9 protein; contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
32	msp-49	C34F11.6	n/a	chrII 5,194,543	msp-49 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
33	ssp-11	T28H11.6	n/a	chrIV 4,999,632	C. elegans SSP-11 protein; contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
34	ZK666.8	ZK666.8	n/a	chrII 10,492,235	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
35	K01H12.4	K01H12.4	n/a	chrIV 9,714,029	contains similarity to Simian T-lymphotropic virus 1 Rex p27 protein (Fragment).; TR:O12387
36	C17F3.3	C17F3.3	n/a	chrI 6,682,871	contains similarity to Interpro domains IPR000956 (Stathmin), IPR005819 (Histone H5), IPR000533 (Tropomyosin), IPR005398 (Tubby, N-terminal)
37	T28H11.7	T28H11.7	n/a	chrIV 5,015,779	contains similarity to Interpro domain IPR004148 (BAR)
38	Y81G3A.1	Y81G3A.1	n/a	chrII 13,082,998	Y81G3A.1 encodes a nematode-specific sperm protein; Y81G3A.1 has no obvious non-nematode homologs, but does have a putative central coiled-coil domain, and is is paralogous to four other C. elegans proteins (B0207.11, F42G4.6, F44F4.10, and T08G11.2); Y81G3A.1(RNAi) animals exhibit aldicarb resistance; Y81G3A.1 expression is enriched in spermatogenesis.
39	F40H6.1	F40H6.1	n/a	chrIII 6,057,696
40	W03D8.5	W03D8.5	n/a	chrI 2,817,203	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
41	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
42	Y6E2A.8	Y6E2A.8	n/a	chrV 15,725,749	contains similarity to Encephalitozoon cuniculi UPF0329 protein ECU05_1680/ECU11_0050.; SW:Q8STA9
43	C15A11.2	C15A11.2	n/a	chrI 7,388,033	contains similarity to Cryptosporidium hominis Putative uncharacterized protein.; TR:Q5CF92
44	R02F2.5	R02F2.5	n/a	chrIII 5,479,799	contains similarity to Interpro domains IPR003267 (Small proline-rich), IPR000694 (Proline-rich region)
45	C08H9.10	C08H9.10	n/a	chrII 9,854,672	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
46	ssq-4	T28H11.1	n/a	chrIV 5,017,101	C. elegans SSQ-4 protein; contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR002952 (Eggshell protein), IPR000817 (Prion protein), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR000158 (Cell division protein FtsZ, N-terminal), IPR013286 (Annexin, type VII)
47	C38C3.3	C38C3.3	n/a	chrV 1,497,058
48	ttr-3	K03H1.3	n/a	chrIII 9,926,034	K03H1.3 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
49	sss-1	F32B6.5	n/a	chrIV 9,893,216	C. elegans SSS-1 protein ;
50	clec-251	F11D11.8	n/a	chrV 18,746,563	C. elegans CLEC-251 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)