UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZC132.9	ZC132.9	4e-139	chrV 4,318,616
2	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
3	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
5	glb-14	F21A3.6	n/a	chrV 15,543,990	glb-14 encodes a globin with no obvious function in mass RNAi assays; glb-14 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-14 is downregulated in a daf-2(e1370) mutant background under normoxic conditions.
6	F12A10.5	F12A10.5	n/a	chrII 5,481,296	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
7	sru-6	C33A12.8	n/a	chrIV 9,491,282	C. elegans SRU-6 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
8	cyn-9	T27D1.1	n/a	chrIII 3,698,740	cyn-9 encodes a peptidyl prolyl cis-trans isomerase most similar to human cyclophilin G (OMIM:606093); CYN-9 likely functions as a catalyst in the folding and modification of cuticle collagens; a cyn-9::lacZ reporter is expressed in the syncytial hypodermis from early larval through adult stages; cyn-9 mRNA is expressed most strongly at the mid-L3 and mid-L4 larval stages, the intermoult period when collagens are synthesized.
9	clec-256	Y17D7B.6	n/a	chrV 18,772,129	C. elegans CLEC-256 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	ZK1010.6	ZK1010.6	n/a	chrIII 12,989,808	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domain IPR002593 (Protein of unknown function DX)
11	C44F1.1	C44F1.1	n/a	chrIII 3,761,814	contains similarity to Interpro domain IPR008967 (p53-like transcription factor, DNA-binding)
12	C52A10.2	C52A10.2	n/a	chrV 5,235,946	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
13	Y57A10C.9	Y57A10C.9	n/a	chrII 12,434,642	contains similarity to Nitrosomonas europaea Possible ABC transport permease.; TR:Q82XY6
14	F45E1.2	F45E1.2	n/a	chrX 8,003,850
15	F52F10.1	F52F10.1	n/a	chrV 1,560,979
16	T28B4.2	T28B4.2	n/a	chrX 6,582,753
17	nas-32	T02B11.7	n/a	chrV 897,042	C. elegans NAS-32 protein; contains similarity to Pfam domains PF01549 (ShK domain-like) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site), IPR003582 (Metridin-like ShK toxin)
18	T11B7.2	T11B7.2	n/a	chrIV 8,844,038	contains similarity to Homo sapiens remodeling and spacing factor 1; ENSEMBL:ENSP00000311513
19	C29F4.3	C29F4.3	n/a	chrIV 11,222,963	contains similarity to Spodoptera litura nucleopolyhedrovirus Hypothetical protein.; TR:Q91BF2
20	ZK228.3	ZK228.3	n/a	chrV 18,459,731	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
21	F23F1.3	F23F1.3	n/a	chrII 32,686
22	T09E11.3	T09E11.3	n/a	chrI 12,369,888	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
23	C05E7.3	C05E7.3	n/a	chrX 12,946,010	contains similarity to Triticum aestivum Cold acclimation protein WCOR410b.; TR:P93607
24	B0244.4	B0244.4	n/a	chrIII 5,749,496	contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR017452 (GPCR, rhodopsin-like superfamily)
25	tba-9	F40F4.5	n/a	chrX 3,254,559	tba-9 encodes one of nine C. elegans alpha tubulins; by homology, TBA-9 is predicted to be a component of microtubules; as loss of tba-9 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, TBA-9 likely functions redundantly with other alpha tubulins as a basic component of cellular architecture that may play additional roles in processes such as cell division, cell movement, and intracellular transport.
26	F19B2.7	F19B2.7	n/a	chrV 20,150,407	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
27	fbxa-110	Y102A5C.8	n/a	chrV 16,937,848	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
28	gon-1	F25H8.3	n/a	chrIV 9,940,393	gon-1 encodes a functional metalloprotease that defines a new sub-family of secreted proteases known as MPT (metalloprotease with thrombospondin type 1 repeats); the other two members of this family are the bovine procollagen I N-protease ( PINP ) and the murine enzyme ADAMTS-1; gon-1 is essential for hermaphrodite gonadal morphogenesis; sequence homology with other metalloproteases suggests that it functions by remodelling the extracellular matrix; GON-1 is expressed at high levels within the gonadal distal tip cell during migration.
29	mom-1	T07H6.2	n/a	chrX 6,295,619	mom-1 encodes a predicted O-acyltransferase that is orthologous to Porcupine proteins conserved across a wide range of species; MOM-1 functions as part of a Wnt/MAPK signaling pathway that is required maternally for endoderm induction in the early embryo; by homology, MOM-1 is predicted to be a membrane-spanning endoplasmic reticulum protein that stimulates post-translational processing of Wnt signaling molecules such as MOM-2; embryonic mosaic analysis indicates that MOM-1 activity is required in the signaling cell, P2, for proper specification of endoderm, consistent with its predicted role in processing MOM-2/Wnt.
30	pgp-12	F22E10.1	n/a	chrX 12,734,558	pgp-12 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of ATP-binding cassette (ABC) transporters; although loss of pgp-12 function via mutation or RNAi results in no obvious defects, pgp-12 promoter fusion constructs reveal expression in the excretory cell, consistent with a role for pgp-12 in metabolite transporter activity; pgp-12 expression is regulated by the DCP-66 transcription factor which binds the pgp-12 Ex-1 promoter element in yeast one-hybrid and EMSA experiments.
31	C08H9.1	C08H9.1	n/a	chrII 9,876,448	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
32	gcy-11	C30G4.3	n/a	chrX 17,049,964	C. elegans GCY-11 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00211 (Adenylate and Guanylate cyclase catalytic domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001054 (Adenylyl cyclase class-3/4/guanylyl cyclase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
33	sdz-8	C55A6.5	n/a	chrV 11,515,643	C. elegans SDZ-8 protein; contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
34	M03F8.4	M03F8.4	n/a	chrV 5,932,159	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
35	W05H9.3	W05H9.3	n/a	chrX 6,252,987
36	F15G9.5	F15G9.5	n/a	chrX 9,735,456	contains similarity to Homo sapiens Fibrillin 2 precursor; ENSEMBL:ENSP00000262464
37	sru-27	C38C3.2	n/a	chrV 1,500,054	C. elegans SRU-27 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
38	F22E5.1	F22E5.1	n/a	chrII 2,676,663	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
39	K10C8.2	K10C8.2	n/a	chrV 12,691,417	K10C8.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K10C8.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
40	F56F10.2	F56F10.2	n/a	chrX 861,193	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
41	che-13	F59C6.7	n/a	chrI 10,511,288	che-13 encodes a novel protein homologous to mammalian IFT57/Hippi (OMIM:606621, protein interactor of Huntingtin-interacting protein 1 that is implicated in neuronal apoptosis in the Huntington disease state); CHE-13 is a proposed component of the intraflagellar transport (IFT) complex B, and is required for the construction and maintenance of cilia on a subset of sensory neurons; in addition, CHE-13 is required for proper localization of OSM-5, a murine polaris homolog, to IFT complex B; CHE-13 is expressed in ciliated sensory neurons including the amphids, phasmids, inner and outer labial neurons, and sensory rays of the male tail, localizing to the cilia base (transition zone) as well as to the axoneme; che-13 expression, like that of ciliogenic genes osm-1, osm-5, osm-6, and che-2, is positively regulated by the DAF-19 RFX-type transcription factor.
42	srw-20	T05E12.4	n/a	chrV 17,079,045	C. elegans SRW-20 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
43	irk-3	K04G11.5	n/a	chrX 14,356,108	C. elegans IRK-3 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
44	T10B10.5	T10B10.5	n/a	chrX 15,197,450	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
45	F13A7.7	F13A7.7	n/a	chrV 16,382,944	contains similarity to Saccharomyces cerevisiae Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis; SGD:YGR159C
46	F54B11.9	F54B11.9	n/a	chrX 13,607,737	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I5W3
47	ire-1	C41C4.4	n/a	chrII 8,118,482	ire-1 encodes a transmembrane serine/threonine protein kinase and site-specific endoribonuclease orthologous to Saccharomyces cerevisiae inositol-requiring 1 protein kinase (Ire1) and human endoplasmic reticulum-to-nucleus signaling 1 (ERN1, OMIM:604033); IRE-1 is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); in response to ER stress, IRE-1 cleaves xbp-1 mRNA to produce transcriptionally active XBP-1 that positively regulates UPR gene expression in order to maintain ER homeostasis.
48	R09B5.11	R09B5.11	n/a	chrV 1,440,531	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
49	T20F7.5	T20F7.5	n/a	chrX 16,850,352	contains similarity to Interpro domain IPR000694 (Proline-rich region)
50	nas-29	F58A6.4	n/a	chrII 5,140,235	C. elegans NAS-29 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)