UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y6B3B.9	Y6B3B.9	0	chrI 13,743,033	contains similarity to Pfam domain PF04031 Las1-like contains similarity to Interpro domain IPR007174 (Las1-like)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C01F1.2	C01F1.2	n/a	chrII 4,300,243	C01F1.2 is orthologous to the human gene SCO (CYTOCHROME OXIDASE DEFICIENT, YEAST) HOMOLOG 1 (SCO1; OMIM:603644), which when mutated leads to early-onset hepatic failure; the C01F1.2 protein is predicted to be mitochondrial with 68% accuracy.
4	F54E2.5	F54E2.5	n/a	chrV 2,814,230	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domains IPR006874 (Protein of unknown function DUF621), IPR003091 (Voltage-dependent potassium channel)
5	T10D4.6	T10D4.6	n/a	chrII 3,121,247	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR009057 (Homeodomain-like)
6	E02C12.6	E02C12.6	n/a	chrV 9,370,290	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
7	F23F1.4	F23F1.4	n/a	chrII 26,912
8	C06H5.6	C06H5.6	n/a	chrV 17,884,381	contains similarity to Pfam domains PF00083 (Sugar (and other) transporter) , PF07690 (Major Facilitator Superfamily) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
9	T10F2.4	T10F2.4	n/a	chrIII 5,171,158	contains similarity to Pfam domains PF08606 (Prp19/Pso4-like) , PF00400 (WD domain, G-beta repeat) (6)contains similarity to Interpro domains IPR003613 (U box), IPR011046 (WD40 repeat-like), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR009053 (Prefoldin), IPR001680 (WD40 repeat), IPR013915 (Pre-mRNA-splicing factor 19), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
10	R02E12.4	R02E12.4	n/a	chrX 4,005,562	contains similarity to Pfam domains PF03148 (Tektin family) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000435 (Tektin), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
11	Y47H9C.2	Y47H9C.2	n/a	chrI 11,842,812	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domain IPR001594 (Zinc finger, DHHC-type)
12	F09E10.5	F09E10.5	n/a	chrX 1,492,033
13	C52B9.4	C52B9.4	n/a	chrX 4,262,578	contains similarity to Pfam domain PF06814 Lung seven transmembrane receptor contains similarity to Interpro domains IPR009637 (Transmembrane receptor, eukaryota), IPR008983 (Tumour necrosis factor-like)
14	cdr-1	F35E8.11	n/a	chrV 15,922,065	cdr-1 encodes a member of the cadmium-inducible lysosomal family that affects susceptibility to cadmium toxicity; expressed in intestinal cells.
15	dcs-1	Y113G7A.9	n/a	chrV 20,084,683	dcs-1 encodes a scavenger mRNA decapping enzyme; dcs-1 exhibits hydrolase activity in vitro, with specificity for 7meGMP in its primary nucleoside monophosphate binding site; dcs-1 is the upstream gene in an operon with fre-1, which encodes an NADPH-dependent flavin reductase; reporter fusions using dcs-1 upstream sequence direct expression throughout the life cycle in neurons and pharyngeal muscle; expression is present in dauer larvae and enhanced by heat shock.
16	F53F1.3	F53F1.3	n/a	chrV 13,409,019	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
17	folt-1	C06H2.4	n/a	chrV 11,142,257	folt-1 encodes a folate transporter required for folate uptake; FOLT-1 is orthologous to human SLC19A1 (OMIM:600424), SLC19A2 (OMIM:603941, mutated in thiamine-responsive megaloblastic anemia syndrome), and SLC19A3 (OMIM:606152, mutated in biotin-responsive basal ganglia disease); heterologously expressed FOLT-1 transports folate in vitro; FOLT-1 activity is acid-dependent, is sodium-independent, and is inhibited by folate derivatives, sulfasalazine, or anion transport inhibitors such as 4,4''-diisothio-cyanatostilbene-2,2''-disulphonic acid (DIDS); folt-1(ok1460) and folt-1(RNAi) animals show significantly lowered folate uptake; folt-1 is expressed in several tissues, including (most strongly) pharynx and posterior intestine, as well as head, body wall, and vulva muscles, and gonad sheath cells; FOLT-1's intestinal expression diminishes with age from larvae to adults; both FOLT-1 intestinal expression and whole-animal folate uptake are lowered in folate-supplemented food media; FOLT-1 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with its paralogs FOLT-2 and FOLT-3; however, folt-1(ok1460) mutants are sluggish and sterile, which might instead indicate that FOLT-1 is required for locomotion and fertility.
18	srd-72	Y45G12C.9	n/a	chrV 2,533,025	C. elegans SRD-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001614 (Myelin proteolipid protein PLP), IPR003002 (7TM chemoreceptor, subfamily 1), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
19	clec-187	ZK896.6	n/a	chrIV 12,870,360	C. elegans CLEC-187 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
20	ZK742.3	ZK742.3	n/a	chrV 7,809,120	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
21	ZK836.3	ZK836.3	n/a	chrV 12,195,261
22	Y45F10D.6	Y45F10D.6	n/a	chrIV 13,797,043
23	nhr-253	ZK6.4	n/a	chrV 397,792	C. elegans NHR-253 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000679 (Zinc finger, GATA-type), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	T13H5.4	T13H5.4	n/a	chrII 8,524,376	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR000690 (Zinc finger, C2H2-type matrin)
25	F13E6.5	F13E6.5	n/a	chrX 10,696,500	contains similarity to Pfam domain PF01569 PAP2 superfamily contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR016118 (Phosphatidic acid phosphatase/chloroperoxidase, N-terminal)
26	F10E7.10	F10E7.10	n/a	chrII 7,114,773	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
27	cdr-6	K01D12.12	n/a	chrV 12,413,079	C. elegans CDR-6 protein; contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR010987 (Glutathione S-transferase, C-terminal-like)
28	cyp-43A1	E03E2.1	n/a	chrX 5,716,005	C. elegans CYP-43A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
29	pac-1	C04D8.1	n/a	chrIII 8,508,167	C. elegans PAC-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00169 (PH domain) contains similarity to Interpro domains IPR008936 (Rho GTPase activation protein), IPR001849 (Pleckstrin-like), IPR000104 (Antifreeze protein, type I), IPR011993 (Pleckstrin homology-type), IPR000198 (RhoGAP)
30	K01A12.2	K01A12.2	n/a	chrX 8,618,599
31	C35B1.2	C35B1.2	n/a	chrIV 4,094,546	n/a
32	nhr-166	C49D10.2	n/a	chrII 3,881,165	C. elegans NHR-166 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
33	F39B1.1	F39B1.1	n/a	chrX 15,240,527	contains similarity to Pfam domains PF00454 (Phosphatidylinositol 3- and 4-kinase) , PF00168 (C2 domain) , PF00787 (PX domain) , PF02809 (Ubiquitin interaction motif) , PF00613 (Phosphoinositide 3-kinase family, accessory domain (PIK domain)) , PF00792 (Phosphoinositide 3-kinase C2) contains similarity to Interpro domains IPR001263 (Phosphoinositide 3-kinase accessory region PIK), IPR002420 (Phosphoinositide 3-kinase, C2), IPR001683 (Phox-like), IPR011009 (Protein kinase-like), IPR000694 (Proline-rich region), IPR003903 (Ubiquitin interacting motif), IPR000403 (Phosphatidylinositol 3- and 4-kinase, catalytic), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR015433 (Phosphatidylinositol Kinase), IPR016024 (Armadillo-type fold), IPR000341 (Phosphoinositide 3-kinase, ras-binding), IPR000008 (C2 calcium-dependent membrane targeting)
34	F23H11.2	F23H11.2	n/a	chrIII 897,957	contains similarity to Interpro domains IPR001228 (4-diphosphocytidyl-2C-methyl-D-erythritol synthase), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
35	F53E10.1	F53E10.1	n/a	chrV 2,617,140	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR011037 (Pyruvate kinase, beta-barrel-like)
36	W04B5.4	W04B5.4	n/a	chrIII 2,408,633	W04B5.4 encodes a putative mitochondrial ribosomal protein L30 that inhibits DHC-1 in vivo; W04B5.4 is orthologous to human MRPL3; W04B5.4(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that W04B5.4 negatively regulates dynein; W04B5.4 is required for embryonic and larval development in mass RNAi assays.
37	taf-2	Y37E11B.4	n/a	chrIV 3,588,951	taf-2 encodes a member of the peptidase M1 family, a predicted aminopeptidase with similarity to human TBP-associated factor 2.
38	Y45G12B.3	Y45G12B.3	n/a	chrV 2,691,488	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
39	R13A5.10	R13A5.10	n/a	chrIII 7,582,468	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
40	math-40	T08E11.3	n/a	chrII 1,831,237	C. elegans MATH-40 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
41	ZK177.2	ZK177.2	n/a	chrII 5,519,681	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
42	F09G8.3	F09G8.3	n/a	chrIII 8,266,869	contains similarity to Pfam domain PF00380 Ribosomal protein S9/S16 contains similarity to Interpro domains IPR000754 (Ribosomal protein S9), IPR014721 (Ribosomal protein S5 domain 2-type fold)
43	D2021.8	D2021.8	n/a	chrX 8,552,722	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
44	F52C12.2	F52C12.2	n/a	chrIV 1,956,651	contains similarity to Pfam domains PF04068 (Possible metal-binding domain in RNase L inhibitor, RLI) , PF04034 (Domain of unknown function (DUF367)) contains similarity to Interpro domains IPR007209 (Possible metal-binding region in RNase L inhibitor, RLI), IPR007177 (Protein of unknown function DUF367)
45	C05G5.1	C05G5.1	n/a	chrX 14,737,200	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
46	H11E01.2	H11E01.2	n/a	chrX 1,623,360	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
47	C04C3.3	C04C3.3	n/a	chrIV 3,401,683	contains similarity to Pfam domains PF02780 (Transketolase, C-terminal domain) , PF02779 (Transketolase, pyrimidine binding domain) contains similarity to Interpro domains IPR005476 (Transketolase, C-terminal), IPR005475 (Transketolase, central region), IPR015941 (Transketolase C-terminal-like)
48	fbxa-156	C06H5.1	n/a	chrV 17,896,012	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
49	Y45F10D.7	Y45F10D.7	n/a	chrIV 13,792,547	Y45F10D.7 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of human WDR36, mutations in which cause primary open angle glaucoma type 1G (GLC1G, OMIM:609887); large-scale RNAi experiments indicate that Y45F10D.7 activity is required for embryonic and larval development; the Saccharomyces cerevisiae homolog of WDR36, Utp21, is a component of the small-subunit (SSU) processome required for formation of 18S rRNA.
50	ncbp-1	F37E3.1	n/a	chrI 6,423,903	F37E3.1 encodes a putative nuclear cap-binding complex subunit ('CBP80') orthologous to budding yeast STO1 and human NCBP1 (OMIM:600469); in RNAi assays, F37E3.1 is required for embryonic and vulval development, normal locomotion, and general viability; by orthology to NCBP1, F37E3.1 is expected to participate in nonsense-mediated mRNA decay via a pioneer round of translation; F37E3.1(RNAi) induces expression of a gpdh-1::GFP transgene, perhaps because F37E3.1 prevents protein misfolding.