UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y57A10C.9	Y57A10C.9	3.9999999999999997e-134	chrII 12,434,642	contains similarity to Nitrosomonas europaea Possible ABC transport permease.; TR:Q82XY6
2	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
3	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
4	F35D11.1	F35D11.1	n/a	chrII 4,627,370
5	T28B4.2	T28B4.2	n/a	chrX 6,582,753
6	ins-32	Y8A9A.6	n/a	chrII 3,803,141	ins-32 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-32 is one of 38 insulin-like peptides in C. elegans and the precise role of INS-32 in C. elegans development is not yet clear as loss of INS-32 function does not result in a mutant phenotype.
7	dhc-1	T21E12.4	n/a	chrI 4,394,384	dhc-1 encodes a cytoplasmic dynein heavy chain homolog required in one-cell embryos for pronuclear migration, centrosome separation, centrosome proximity to the male pronucleus, and mitotic spindle orientation, suggesting that DHC-1 helps position the microtubule organizing center; DHC-1 genetically interacts with SPD-5, a coiled-coil centrosomal protein.
8	nhr-195	F59E11.10	n/a	chrV 8,971,529	C. elegans NHR-195 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
9	tpi-1	Y17G7B.7	n/a	chrII 12,038,108	tpi-1 encodes a putative triosephosphate isomerase orthologous to human TPI1 (OMIM:190450, mutated in TPI deficiency) and Drosophila WASTED AWAY; despite the severity of TPI mutant phenotypes in humans and Drosophila, TPI-1 has no obvious function in mass RNAi assays.
10	che-13	F59C6.7	n/a	chrI 10,511,288	che-13 encodes a novel protein homologous to mammalian IFT57/Hippi (OMIM:606621, protein interactor of Huntingtin-interacting protein 1 that is implicated in neuronal apoptosis in the Huntington disease state); CHE-13 is a proposed component of the intraflagellar transport (IFT) complex B, and is required for the construction and maintenance of cilia on a subset of sensory neurons; in addition, CHE-13 is required for proper localization of OSM-5, a murine polaris homolog, to IFT complex B; CHE-13 is expressed in ciliated sensory neurons including the amphids, phasmids, inner and outer labial neurons, and sensory rays of the male tail, localizing to the cilia base (transition zone) as well as to the axoneme; che-13 expression, like that of ciliogenic genes osm-1, osm-5, osm-6, and che-2, is positively regulated by the DAF-19 RFX-type transcription factor.
11	C41C4.3	C41C4.3	n/a	chrII 8,110,504	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
12	srx-35	T01C4.5	n/a	chrV 7,121,587	C. elegans SRX-35 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
13	F13A7.7	F13A7.7	n/a	chrV 16,382,944	contains similarity to Saccharomyces cerevisiae Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis; SGD:YGR159C
14	col-123	W08D2.6	n/a	chrIV 9,822,477	col-123 is homologous to the human gene A TYPE IV COLLAGEN (COL6A1; OMIM:303631), which when mutated is sometimes associated with diffuse leiomyomatosis.
15	F02C9.2	F02C9.2	n/a	chrV 3,135,542	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domains IPR005049 (Protein of unknown function DUF288), IPR002972 (Prostaglandin D synthase)
16	T09E11.3	T09E11.3	n/a	chrI 12,369,888	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
17	srd-31	F07C4.8	n/a	chrV 7,634,059	C. elegans SRD-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	glb-14	F21A3.6	n/a	chrV 15,543,990	glb-14 encodes a globin with no obvious function in mass RNAi assays; glb-14 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-14 is downregulated in a daf-2(e1370) mutant background under normoxic conditions.
19	F21A9.2	F21A9.2	n/a	chrI 3,707,420	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
20	ZC132.5	ZC132.5	n/a	chrV 4,306,648	contains similarity to Pfam domain PF05380 Pao retrotransposon peptidase contains similarity to Interpro domains IPR008042 (Retrotransposon, Pao), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
21	F54A5.2	F54A5.2	n/a	chrI 966,565	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
22	nhr-266	F56H1.2	n/a	chrI 5,738,931	C. elegans NHR-266 protein; contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR003125 (Protein of unknown function WSN)
23	gcy-11	C30G4.3	n/a	chrX 17,049,964	C. elegans GCY-11 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00211 (Adenylate and Guanylate cyclase catalytic domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001054 (Adenylyl cyclase class-3/4/guanylyl cyclase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
24	M04C9.4	M04C9.4	n/a	chrI 9,356,115	contains similarity to Bos taurus Osteopontin precursor (Bone sialoprotein 1).; SW:OSTP_BOVIN
25	puf-9	W06B11.2	n/a	chrX 5,843,741	The puf-9 gene encodes a predicted RNA binding protein orthologous to Drosophila PUMILIO and human PUMILIO 2 (OMIM:607205); PUF-9 is required for normal locomotion and fluid balance, and is expressed primarily in somatic tissues; PUF-9 contains a glutamine/asparagine-rich domain.
26	T08B6.1	T08B6.1	n/a	chrIV 4,887,059
27	Y48A6C.1	Y48A6C.1	n/a	chrIII 11,104,510	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
28	ZC482.3	ZC482.3	n/a	chrIII 12,762,606	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
29	T10D4.1	T10D4.1	n/a	chrII 3,151,352	contains similarity to Pfam domains PF01579 (Domain of unknown function DUF19) , PF02343 (Domain of unknown function DUF130) contains similarity to Interpro domains IPR003326 (Protein of unknown function DUF130), IPR002542 (Protein of unknown function DUF19)
30	F54E2.4	F54E2.4	n/a	chrV 2,806,913	contains similarity to Pfam domains PF00047 (Immunoglobulin domain) , PF07679 (Immunoglobulin I-set domain) (3)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR013098 (Immunoglobulin I-set), IPR009134 (Vascular endothelial growth factor receptor, VEGFR, N-terminal), IPR013783 (Immunoglobulin-like fold), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
31	Y37A1A.3	Y37A1A.3	n/a	chrIV 13,900,330	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
32	fbxa-102	K03D7.7	n/a	chrV 17,492,710	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
33	mom-1	T07H6.2	n/a	chrX 6,295,619	mom-1 encodes a predicted O-acyltransferase that is orthologous to Porcupine proteins conserved across a wide range of species; MOM-1 functions as part of a Wnt/MAPK signaling pathway that is required maternally for endoderm induction in the early embryo; by homology, MOM-1 is predicted to be a membrane-spanning endoplasmic reticulum protein that stimulates post-translational processing of Wnt signaling molecules such as MOM-2; embryonic mosaic analysis indicates that MOM-1 activity is required in the signaling cell, P2, for proper specification of endoderm, consistent with its predicted role in processing MOM-2/Wnt.
34	dpy-22	F47A4.2	n/a	chrX 9,816,134	dpy-22 encodes a broadly expressed protein, homologous to the human transcriptional mediator protein TRAP230, which is involved in WNT and RAS signaling, as well as in dosage compensation; DPY-22 has a C-terminal glutamine-rich domain that is dispensable for inhibition of RAS-dependent cell differentiation, but is required for inhibition of BAR-1-dependent gene expression.
35	C08H9.1	C08H9.1	n/a	chrII 9,876,448	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
36	srd-63	F13A7.2	n/a	chrV 16,393,128	C. elegans SRD-63 protein ;
37	sru-27	C38C3.2	n/a	chrV 1,500,054	C. elegans SRU-27 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
38	tag-336	Y69H2.12	n/a	chrV 18,653,219	C. elegans TAG-336 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (7), PF00858 (Amiloride-sensitive sodium channel) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR001873 (Na+ channel, amiloride-sensitive)
39	ZC132.9	ZC132.9	n/a	chrV 4,318,616
40	twk-25	M04B2.5	n/a	chrIV 11,507,989	C. elegans TWK-25 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
41	str-224	K10C9.8	n/a	chrV 1,057,769	C. elegans STR-224 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	F41C6.7	F41C6.7	n/a	chrX 6,883,839	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
43	srh-186	F36G9.2	n/a	chrV 15,956,387	C. elegans SRH-186 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	Y17D7C.2	Y17D7C.2	n/a	chrV 18,717,931	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
45	F15G9.5	F15G9.5	n/a	chrX 9,735,456	contains similarity to Homo sapiens Fibrillin 2 precursor; ENSEMBL:ENSP00000262464
46	sra-1	AH6.4	n/a	chrII 9,520,857	sra-1 encodes a predicted seven transmembrane receptor; expressed in the male SPD and SPV neurons.
47	R06F6.6	R06F6.6	n/a	chrII 10,807,531	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR013847 (POU), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
48	F38A1.11	F38A1.11	n/a	chrIV 1,248,205	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
49	T03E6.2	T03E6.2	n/a	chrV 16,582,078	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	srt-72	C36C5.9	n/a	chrV 3,148,851	C. elegans SRT-72 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000215 (Protease inhibitor I4, serpin)