UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	xrn-2	Y48B6A.3	0	chrII 14,160,796	C. elegans XRN-2 protein; contains similarity to Pfam domain PF03159 XRN 5'-3' exonuclease N-terminus contains similarity to Interpro domains IPR017151 (5'-3' exoribonuclease 2), IPR004859 (Putative 5-3 exonuclease), IPR002952 (Eggshell protein), IPR001878 (Zinc finger, CCHC-type)
2	lgc-21	C33G3.3	n/a	chrX 14,065,977	C. elegans LGC-21 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
3	sre-27	Y57A10C.3	n/a	chrII 12,416,469	C. elegans SRE-27 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
4	T24D11.1	T24D11.1	n/a	chrX 16,409,674	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
5	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
6	C01F1.1	C01F1.1	n/a	chrII 4,303,435	contains similarity to Pfam domain PF05793 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) contains similarity to Interpro domains IPR011991 (Winged helix repressor DNA-binding), IPR008851 (Transcription initiation factor IIF, alpha subunit), IPR011039 (Transcription Factor IIF, Rap30/Rap74, interaction)
7	F39H12.1	F39H12.1	n/a	chrX 836,268	contains similarity to Homo sapiens nuclear pore complex-associated protein TPR; ENSEMBL:ENSP00000356448
8	F39B1.1	F39B1.1	n/a	chrX 15,240,527	contains similarity to Pfam domains PF00454 (Phosphatidylinositol 3- and 4-kinase) , PF00168 (C2 domain) , PF00787 (PX domain) , PF02809 (Ubiquitin interaction motif) , PF00613 (Phosphoinositide 3-kinase family, accessory domain (PIK domain)) , PF00792 (Phosphoinositide 3-kinase C2) contains similarity to Interpro domains IPR001263 (Phosphoinositide 3-kinase accessory region PIK), IPR002420 (Phosphoinositide 3-kinase, C2), IPR001683 (Phox-like), IPR011009 (Protein kinase-like), IPR000694 (Proline-rich region), IPR003903 (Ubiquitin interacting motif), IPR000403 (Phosphatidylinositol 3- and 4-kinase, catalytic), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR015433 (Phosphatidylinositol Kinase), IPR016024 (Armadillo-type fold), IPR000341 (Phosphoinositide 3-kinase, ras-binding), IPR000008 (C2 calcium-dependent membrane targeting)
9	W08F4.7	W08F4.7	n/a	chrII 576,333
10	cdd-1	C47D2.2	n/a	chrX 8,209,904	cdd-1 encodes a cytidine deaminase that contains a zinc-binding region; expressed in the intestine.
11	R03H10.7	R03H10.7	n/a	chrII 4,177,232	contains similarity to Pfam domain PF01336 OB-fold nucleic acid binding domain contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR004365 (Nucleic acid binding, OB-fold, tRNA/helicase-type)
12	H25P06.1	H25P06.1	n/a	chrI 11,317,448	contains similarity to Pfam domains PF00349 (Hexokinase) , PF03727 (Hexokinase) contains similarity to Interpro domain IPR001312 (Hexokinase)
13	R13A5.10	R13A5.10	n/a	chrIII 7,582,468	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
14	T04F8.6	T04F8.6	n/a	chrX 11,669,654	contains similarity to Interpro domain IPR011992 (EF-Hand type)
15	F58H7.2	F58H7.2	n/a	chrIV 942,839	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR015830 (Amidase, fungi type)
16	ZK1321.1	ZK1321.1	n/a	chrII 9,754,525	contains similarity to Sulfolobus sp NOB8H2 Hypothetical protein.; TR:O93705
17	VT23B5.2	VT23B5.2	n/a	chrIV 12,671,338	VT23B5.2 encodes a BEACH-WD40 domain-containing protein that is orthologous to human WDFY3 (WD repeat and FYVE domain containing 3); loss of VT23B5.2 activity via mutation or large-scale RNAi screens in a wild-type background results in no obvious abnormalities.
18	C06H5.6	C06H5.6	n/a	chrV 17,884,381	contains similarity to Pfam domains PF00083 (Sugar (and other) transporter) , PF07690 (Major Facilitator Superfamily) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
19	pgp-4	F42E11.1	n/a	chrX 11,361,531	pgp-4 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-4 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-4 activity via deletion mutations or RNAi results in no obvious defects, the precise role of PGP-4 in C. elegans development and/or behavior is not yet known; pgp-4 promoter-gfp fusion proteins are expressed in the larval excretory cell.
20	T07F8.2	T07F8.2	n/a	chrII 7,145,876	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
21	lam-2	C54D1.5	n/a	chrX 7,147,481	lam-2 encodes a laminin gamma subunit; lam-2 activity is required for embryonic development and for regulation of muscle arm extension; loss of lam-2 function via large-scale RNAi screens results in embryonic, larval, and adult lethality, sterility, body morphology defects, and abnormal locomotion.
22	F53G12.4	F53G12.4	n/a	chrI 135,809
23	lagr-1	Y6B3B.10	n/a	chrI 13,728,317	C. elegans LAGR-1 protein; contains similarity to Pfam domain PF03798 Longevity-assurance protein (LAG1) contains similarity to Interpro domains IPR016439 (Longevity assurance proteins LAG1/LAC1), IPR005547 (Longevity-assurance protein (LAG1)), IPR006634 (TRAM, LAG1 and CLN8 homology)
24	T03D8.2	T03D8.2	n/a	chrV 20,833,812	contains similarity to Pfam domain PF00164 Ribosomal protein S12 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR006032 (Ribosomal protein S12/S23), IPR012340 (Nucleic acid-binding, OB-fold), IPR005679 (Ribosomal protein S12, bacterial-type)
25	T05F1.9	T05F1.9	n/a	chrI 9,646,642	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILP3
26	lips-10	F14E5.5	n/a	chrII 8,440,581	C. elegans LIPS-10 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
27	mep-1	M04B2.1	n/a	chrIV 11,526,270	mep-1 is required for repression by the fem-3 3' UTR in vivo, and for maintenance of somatic (versus germline) differentiation; MEP-1 protein has zinc-finger domains and a glutamine/asparagine-rich domain.
28	DH11.4	DH11.4	n/a	chrII 7,993,221	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
29	C35D10.12	C35D10.12	n/a	chrIII 4,873,622	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR011644 (Haem NO binding), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
30	F44D12.2	F44D12.2	n/a	chrIV 10,015,214	contains similarity to Pfam domain PF01064 Activin types I and II receptor domain contains similarity to Interpro domain IPR000472 (TGF-beta receptor/activin receptor, type I/II)
31	C35B1.2	C35B1.2	n/a	chrIV 4,094,546	n/a
32	ddr-1	C25F6.4	n/a	chrX 5,463,626	The C25F6.4 gene encodes a protein tyrosine kinase homolog that is also homologous to human RS1.
33	F36F12.7	F36F12.7	n/a	chrV 2,099,700
34	Y39E4B.10	Y39E4B.10	n/a	chrIII 13,147,942	contains similarity to Buchnera aphidicola Hypothetical protein BUsg080.; SW:Y080_BUCAP
35	kel-1	C47D12.7	n/a	chrII 11,692,402	kel-1 encodes a BTB/POZ- and Kelch motif-containing protein orthologous to Drosophila Kelch, which is essential for actin organization in ovarian ring canals; in C. elegans, kel-1 is required for regulating feeding during larval development and more specifically, for pharyngeal isthmus peristalsis and efficient trapping of food in the pharynx; KEL-1 is first expressed at the 1.5-fold stage of embryogenesis in the pharyngeal lumen and the nerve ring; later adult and larval expression is confined to the pharyngeal gland cells in which KEL-1 may be required for maintenance of gland cell-specific structures.
36	Y41E3.8	Y41E3.8	n/a	chrIV 15,028,708	contains similarity to Homo sapiens Isoform 1 of H/ACA ribonucleoprotein complex subunit 1; ENSEMBL:ENSP00000226796
37	F16H11.1	F16H11.1	n/a	chrX 4,670,622	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
38	R06A4.8	R06A4.8	n/a	chrII 14,354,036	R06A4.8 is orthologous to the human gene GLYCOGEN DEBRANCHING ENZYME ISOFORM 6 (AGL; OMIM:232400), which when mutated leads to glycogen storage disease, type III.
39	W10G11.17	W10G11.17	n/a	chrII 3,564,777
40	pmp-2	C44B7.9	n/a	chrII 6,885,843	C. elegans PMP-2 protein; contains similarity to Pfam domains PF06472 (ABC transporter transmembrane region 2) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR010509 (ABC transporter, N-terminal), IPR003593 (AAA+ ATPase, core), IPR005283 (Peroxysomal long chain fatty acyl transporter)
41	C44B12.3	C44B12.3	n/a	chrIV 1,105,091
42	F18A11.2	F18A11.2	n/a	chrII 13,034,546	contains similarity to Pfam domain PF00650 CRAL/TRIO domain contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal)
43	F39G3.3	F39G3.3	n/a	chrV 4,732,719	contains similarity to Homo sapiens Isoform 2 of Zinc finger CCCH domain-containing protein 13; ENSEMBL:ENSP00000282007
44	C07A9.5	C07A9.5	n/a	chrIII 9,682,077	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
45	atgp-2	C38C6.2	n/a	chrII 14,641,992	atgp-2 encodes an amino acid transporter glycoprotein subunit; when co-expressed in Xenopus oocytes with either the AAT-1 or AAT-3 catalytic subunit, ATGP-2 facilitates amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; when co-expressed with AAT-9, ATGP-2 is able to enhance the activity of this catalytic subunit; ATGP-2 can covalently associate with AAT-1 or AAT-3 in the Xenopus expression system; when co-expressed with AAT-1 or AAT-3, ATGP-2 localizes to the cell surface of oocytes, but when expressed alone, ATGP-2 localizes intracellularly.
46	C15B12.1	C15B12.1	n/a	chrX 6,477,878	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
47	Y45F10D.7	Y45F10D.7	n/a	chrIV 13,792,547	Y45F10D.7 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of human WDR36, mutations in which cause primary open angle glaucoma type 1G (GLC1G, OMIM:609887); large-scale RNAi experiments indicate that Y45F10D.7 activity is required for embryonic and larval development; the Saccharomyces cerevisiae homolog of WDR36, Utp21, is a component of the small-subunit (SSU) processome required for formation of 18S rRNA.
48	Y45G12B.3	Y45G12B.3	n/a	chrV 2,691,488	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
49	F22E12.1	F22E12.1	n/a	chrV 10,455,572	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR000694 (Proline-rich region)
50	T01C3.2	T01C3.2	n/a	chrV 14,991,380	T01C3.2 encodes a divergent ortholog of Drosophila melanogaster E(Y)2 and budding yeast Sus1p; by orthology, T01C3.2 is predicted to enable both transcriptional activation and silencing in chromatin; however, T01C3.2 has no obvious function in mass RNAi assays.