UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y47D3B.1	Y47D3B.1	0	chrIII 11,385,678	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008166 (Protein of unknown function DUF23), IPR000276 (GPCR, rhodopsin-like)
2	tra-3	LLC1.1	n/a	chrIV 14,440,241	tra-3 encodes an atypical calpain regulatory protease that lacks calcium-binding EF hand domains; during development, TRA-3 likely promotes female development in XX hermaphrodites by cleaving the membrane-associated TRA-2A protein to generate a TRA-2 peptide likely to have feminizing activity; in addition, TRA-3 is one of several proteases that mediate necrotic cell death during neurodegeneration.
3	ugt-59	R11A8.3	n/a	chrIV 10,362,030	C. elegans UGT-59 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
4	F57B10.5	F57B10.5	n/a	chrI 6,563,176	contains similarity to Pfam domain PF01105 emp24/gp25L/p24 family/GOLD contains similarity to Interpro domains IPR009038 (GOLD), IPR000348 (emp24/gp25L/p24)
5	C07G1.7	C07G1.7	n/a	chrIV 8,211,372
6	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
7	T14G12.6	T14G12.6	n/a	chrX 3,758,129	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
8	K10H10.1	K10H10.1	n/a	chrII 14,491,241	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
9	W03F11.5	W03F11.5	n/a	chrI 2,217,759	n/a
10	pac-1	C04D8.1	n/a	chrIII 8,508,167	C. elegans PAC-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00169 (PH domain) contains similarity to Interpro domains IPR008936 (Rho GTPase activation protein), IPR001849 (Pleckstrin-like), IPR000104 (Antifreeze protein, type I), IPR011993 (Pleckstrin homology-type), IPR000198 (RhoGAP)
11	R07B7.8	R07B7.8	n/a	chrV 12,082,679	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
12	F41C3.11	F41C3.11	n/a	chrII 4,732,558	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domains IPR002345 (Lipocalin), IPR005069 (Protein of unknown function DUF271)
13	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
14	F43C1.5	F43C1.5	n/a	chrIII 4,229,767	contains similarity to Pfam domain PF02845 CUE domain contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR009060 (UBA-like)
15	F40E3.2	F40E3.2	n/a	chrI 2,643,222
16	ram-5	T24C2.1	n/a	chrX 14,553,138	ram-5 encodes a novel transmembrane protein; during male tail development, ram-5 activity is required in ray structural cells for proper sensory ray morphogenesis; a RAM-5::GFP fusion protein is expressed in all of the ray structural cells of the male tail, as well as additional sensory support cells in both hermaphrodites and males, including those of the inner labial sensilla as well as the ADE, PDE, and phasmid socket cells.
17	T23C6.5	T23C6.5	n/a	chrX 17,156,542	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR004827 (Basic-leucine zipper (bZIP) transcription factor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
18	C13C12.2	C13C12.2	n/a	chrV 12,524,627	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
19	C45G7.4	C45G7.4	n/a	chrIV 2,434,709	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
20	Y26D4A.3	Y26D4A.3	n/a	chrI 13,072,492	contains similarity to Pfam domain PF00059 (Lectin C-type domain short and long forms)
21	rnf-1	C06A5.9	n/a	chrI 6,010,654	C. elegans RNF-1 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
22	F59B10.3	F59B10.3	n/a	chrII 10,511,687	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
23	F23B2.3	F23B2.3	n/a	chrIV 9,134,019	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
24	Y49F6C.2	Y49F6C.2	n/a	chrII 3,379,231
25	T20B6.3	T20B6.3	n/a	chrIII 2,899,911	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein)
26	W09H1.3	W09H1.3	n/a	chrII 13,184,626	contains similarity to Homo sapiens cDNA FLJ31139 fis, clone IMR322001185; ENSEMBL:ENSP00000380962
27	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
28	K08C9.7	K08C9.7	n/a	chrI 11,495,873	contains similarity to Homo sapiens ubiquitin and ribosomal protein S27a precursor; ENSEMBL:ENSP00000272317
29	Y39A3A.3	Y39A3A.3	n/a	chrIII 2,067,514	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
30	tag-123	F08F1.7	n/a	chrX 8,420,290	C. elegans TAG-123 protein; contains similarity to Pfam domain PF02990 Endomembrane protein 70 contains similarity to Interpro domains IPR008075 (Lipocalin-1 receptor), IPR004240 (Nonaspanin (TM9SF))
31	EGAP9.3	EGAP9.3	n/a	chrV 6,579,135	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
32	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.
33	rgs-6	C41G11.3	n/a	chrX 5,724,513	rgs-6 encodes a regulator of G protein signaling; by homology, RGS-6 is predicted to function as a GTPase-activating protein that binds G protein alpha subunits and negatively regulates heterotrimeric G protein signaling; loss of rgs-6 activity via RNAi or a deletion mutation results in no obvious defects, and likewise, rgs-6 overexpression has no measurable effect on egg-laying behavior, locomotion, or viability; the rgs-6 expression pattern has not yet been reported.
34	pqn-67	T16G1.1	n/a	chrV 12,926,198	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
35	Y57G11C.31	Y57G11C.31	n/a	chrIV 14,685,186	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
36	sri-57	F22E5.16	n/a	chrII 2,671,336	C. elegans SRI-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
37	F39H12.3	F39H12.3	n/a	chrX 839,898	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) (3), PF02197 (Regulatory subunit of type II PKA R-subunit) contains similarity to Interpro domains IPR003117 (cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta), IPR000048 (IQ calmodulin-binding region)
38	btb-12	ZC204.3	n/a	chrII 1,655,685	C. elegans BTB-12 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
39	F48B9.8	F48B9.8	n/a	chrX 2,175,203	contains similarity to Homo sapiens Protein FAM8A1; ENSEMBL:ENSP00000259963
40	thoc-1	T02H6.2	n/a	chrII 705,367	C. elegans THOC-1 protein ; contains similarity to Danio rerio THO complex 1.; TR:Q7SYB2
41	T25G12.1	T25G12.1	n/a	chrX 17,249,457
42	C15C8.5	C15C8.5	n/a	chrV 12,749,106	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
43	T07F10.6	T07F10.6	n/a	chrV 12,865,830	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
44	Y116A8B.5	Y116A8B.5	n/a	chrIV 17,228,490	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
45	F58F6.5	F58F6.5	n/a	chrIV 1,343,974	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domain IPR006874 (Protein of unknown function DUF621)
46	F49E8.6	F49E8.6	n/a	chrIV 7,553,994	contains similarity to Interpro domain IPR000694 (Proline-rich region)
47	F59D12.2	F59D12.2	n/a	chrX 15,674,207	contains similarity to Homo sapiens Calcium-dependent protease, small subunit; ENSEMBL:ENSP00000246533
48	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
49	T14B4.9	T14B4.9	n/a	chrII 6,731,934	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
50	T10F2.4	T10F2.4	n/a	chrIII 5,171,158	contains similarity to Pfam domains PF08606 (Prp19/Pso4-like) , PF00400 (WD domain, G-beta repeat) (6)contains similarity to Interpro domains IPR003613 (U box), IPR011046 (WD40 repeat-like), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR009053 (Prefoldin), IPR001680 (WD40 repeat), IPR013915 (Pre-mRNA-splicing factor 19), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)