UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	W03C9.5	W03C9.5	9e-44	chrII 11,967,205	contains similarity to Arabidopsis thaliana F25C20.11 protein.; TR:Q9SAA3
2	T20B6.2	T20B6.2	n/a	chrIII 2,895,298	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
3	srh-184	D1054.12	n/a	chrV 10,797,485	C. elegans SRH-184 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	JC8.7	JC8.7	n/a	chrIV 13,248,845	contains similarity to Homo sapiens Uncharacterized protein C4orf27; ENSEMBL:ENSP00000261511
5	srt-63	T28A11.15	n/a	chrV 3,255,375	C. elegans SRT-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
6	T16H12.2	T16H12.2	n/a	chrIII 10,086,574	contains similarity to Mus musculus 2310010I16Rik protein.; TR:Q9CWH8
7	srx-41	F59B1.7	n/a	chrV 3,635,917	C. elegans SRX-41 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR004827 (Basic-leucine zipper (bZIP) transcription factor), IPR000276 (GPCR, rhodopsin-like)
8	his-32	F17E9.10	n/a	chrIV 8,334,513	his-32 encodes an H3 histone; by homology, HIS-32 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-32 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
9	T11F9.12	T11F9.12	n/a	chrV 11,494,950	contains similarity to Interpro domain IPR011735 (Conserved hypothetical protein, HtrL)
10	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
11	mys-1	VC5.4	n/a	chrV 7,083,085	mys-1 encodes a MYST family histone acetyltransferase orthologous to Drosophila EG0007.7, human TIP60, and S. cerevisiae Esa1p; during vulval development, mys-1 acts as Class C synMuv gene: mys-1 mutations enhance mutations in components of the C. elegans NuRD and Rb repressor complexes that negatively regulate expression of genes required for vulval induction; in addition, mys-1(RNAi) enhances mutations in pha-4, which encodes a FoxA transcription factor required for pharyngeal organogenesis; mys-1 mutations also cause a synthetic slow growth phenotype in combination with mutations in the MCD-1 zinc-finger protein; thus, mys-1 activity is essential for proper cell fate specification of different cell types at different times during C. elegans development.
12	sra-27	F18C5.1	n/a	chrII 6,569,673	C. elegans SRA-27 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR000344 (Nematode chemoreceptor, Sra), IPR000276 (GPCR, rhodopsin-like)
13	F13B9.6	F13B9.6	n/a	chrX 8,266,671	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
14	nhr-51	K06B4.1	n/a	chrV 15,677,024	C. elegans NHR-51 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	F02C12.3	F02C12.3	n/a	chrX 13,397,291
16	fbxa-95	F28F8.4	n/a	chrV 15,572,053	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
17	B0001.7	B0001.7	n/a	chrIV 12,152,686	contains similarity to Herpestes ichneumon Acetylcholine receptor protein, alpha chain (Fragment).; SW:ACHA_HERIC
18	K12H4.2	K12H4.2	n/a	chrIII 8,047,973	contains similarity to Pfam domain PF02410 Domain of unknown function DUF143 contains similarity to Interpro domain IPR004394 (Iojap-related protein)
19	lgc-17	T01H10.6	n/a	chrX 12,123,239	C. elegans LGC-17 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
20	mut-7	ZK1098.8	n/a	chrIII 9,540,593	mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference.
21	T12A2.1	T12A2.1	n/a	chrIII 6,261,458	contains similarity to Pfam domains PF01979 (Amidohydrolase family) , PF07969 (Amidohydrolase family) contains similarity to Interpro domains IPR011550 (Amidohydrolase-like), IPR013108 (Amidohydrolase 3), IPR006680 (Amidohydrolase 1), IPR005920 (Imidazolonepropionase)
22	hum-1	F29D10.4	n/a	chrI 8,848,443	hum-1 encodes a class I unconventional myosin heavy chain that, within this class, is most closely related to the amoeboid myosin I subclass; loss of hum-1 activity via RNAi results in a low frequency of aldicarb resistance, suggesting that hum-1 may play a role in regulating synapse structure and/or function; when expressed in the DA cholinergic motor neurons, a HUM-1 reporter fusion protein localizes solely to punctate structures.
23	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
24	fbxa-185	F47H4.4	n/a	chrV 17,333,561	C. elegans FBXA-185 protein; contains similarity to Pfam domains PF01485 (IBR domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type)
25	ZK863.1	ZK863.1	n/a	chrV 12,169,192	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
26	Y17D7B.5	Y17D7B.5	n/a	chrV 18,775,675	contains similarity to Interpro domain IPR006583 (CW)
27	srt-7	C50H11.4	n/a	chrV 3,082,398	C. elegans SRT-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000408 (Regulator of chromosome condensation, RCC1)
28	C41D11.4	C41D11.4	n/a	chrI 4,442,876
29	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
30	F54D12.4	F54D12.4	n/a	chrII 1,368,200
31	R09E12.6	R09E12.6	n/a	chrV 767,566	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
32	T12F5.2	T12F5.2	n/a	chrI 3,732,139
33	R09E12.5	R09E12.5	n/a	chrV 770,204
34	wee-1.1	F35H8.7	n/a	chrII 9,582,677	C. elegans WEE-1.1 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
35	C35C5.6	C35C5.6	n/a	chrX 11,566,764	contains similarity to Drosophila melanogaster Flybase gene name is CG2478-PA;; FLYBASE:CG2478
36	dgk-3	F54G8.2	n/a	chrIII 9,165,462	dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
37	C27B7.2	C27B7.2	n/a	chrIV 8,893,280	contains similarity to Arabidopsis thaliana F3O9.12 protein (At1g16320/F3O9_12).; TR:Q9SA31
38	W08F4.1	W08F4.1	n/a	chrII 593,688
39	Y116A8C.13	Y116A8C.13	n/a	chrIV 16,956,392	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR000330 (SNF2-related), IPR001395 (Aldo/keto reductase), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
40	clec-190	M199.4	n/a	chrIV 15,125,488	C. elegans CLEC-190 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
41	gck-4	C04A11.3	n/a	chrX 13,679,590	C. elegans GCK-4 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
42	F10D2.8	F10D2.8	n/a	chrV 7,150,438	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
43	srj-21	F28H7.11	n/a	chrV 10,745,530	C. elegans SRJ-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	F28F8.7	F28F8.7	n/a	chrV 15,579,943	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domain IPR000949 (ELM2)
45	W06G6.9	W06G6.9	n/a	chrV 16,646,169	contains similarity to Ralstonia solanacearum Hypothetical protein RSc2317.; TR:Q8XX01
46	srxa-10	R10E11.7	n/a	chrIII 9,795,820	C. elegans SRXA-10 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
47	F09G2.2	F09G2.2	n/a	chrV 7,197,657	contains similarity to Interpro domain IPR011028 (Cyclin-like)
48	ceeh-1	K02F3.6	n/a	chrIII 830,425	ceeh-1 encodes a soluble epoxide hydrolase (sEH) orthologous to human ABHD7 and ABHD9; recombinant CEEH-1 is biochemically active in vitro on epoxyeicosatrienoic acids and leukotoxins (EpOMEs); conversely, CEEH-1 is inhibited by urea-based antagonists of mammalian sEH that elevate EpOME levels when fed to C. elegans; perhaps because of genetic redundancy with its paralog CEEH-2, CEEH-1 has no obvious function in mass RNAi assays.
49	srab-13	F59A7.3	n/a	chrV 2,026,295	C. elegans SRAB-13 protein ;
50	M01G5.3	M01G5.3	n/a	chrIII 1,513,690	contains similarity to Pfam domain PF07851 TMPIT-like protein contains similarity to Interpro domain IPR012926 (TMPIT-like)