UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	rpb-11	W01G7.3	2.0000000000000002e-66	chrII 14,060,256	C. elegans RPB-11 protein; contains similarity to Pfam domain PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain contains similarity to Interpro domains IPR008193 (DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site), IPR011261 (DNA-directed RNA polymerase, dimerisation), IPR009025 (DNA-directed RNA polymerase, RBP11-like)
2	R10E4.11	R10E4.11	n/a	chrIII 4,299,234	contains similarity to Pfam domain PF00096 (Zinc finger, C2H2 type)
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	F48E3.2	F48E3.2	n/a	chrX 7,491,715	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
5	K10E9.1	K10E9.1	n/a	chrI 196,071
6	F59D12.5	F59D12.5	n/a	chrX 15,646,886
7	F39H11.1	F39H11.1	n/a	chrI 8,697,062	contains similarity to Pfam domain PF07572 Bucentaur or craniofacial development contains similarity to Interpro domains IPR011421 (Bucentaur or craniofacial development), IPR005413 (Low calcium response V antigen)
8	R12C12.5	R12C12.5	n/a	chrII 6,044,615	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
9	exos-1	Y48A6B.5	n/a	chrIII 11,009,701	C. elegans EXOS-1 protein ; contains similarity to Drosophila melanogaster Flybase gene name is Csl4-PA;; FLYBASE:CG6249
10	scpl-2	F45E12.1	n/a	chrII 7,312,591	scpl-2 encodes a putative serine/threonine phosphatase, orthologous to budding yeast Nem1p and human DULLARD; SCPL-2 is expressed in pharynx and intestine; SCPL-2 is distantly similar to FCP-1 and SCPL-1, -3, and -4; by orthology, SCPL-2 is expected to localize to the nuclear envelope, to regulate nuclear membrane biogenesis, and to dephosphorylate the phosphatidic acid phosphatase ortholog H37A05.1.
11	Y26D4A.8	Y26D4A.8	n/a	chrI 13,084,164	contains similarity to Bos taurus Myosin-10 (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb)s(Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellularsmyosin heavy chain, type B) (Non-muscle myosin heavy chain-B) (NMMHC-sB).; SW:Q27991
12	C26E6.3	C26E6.3	n/a	chrIII 4,945,871	contains similarity to Pfam domain PF04078 Cell differentiation family, Rcd1-like contains similarity to Interpro domain IPR007216 (Cell differentiation proteins, Rcd1-like)
13	M04C9.3	M04C9.3	n/a	chrI 9,353,710	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like), IPR000816 (Peptidase C15, pyroglutamyl peptidase I)
14	C01B10.4	C01B10.4	n/a	chrIV 6,630,045	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
15	C48B6.2	C48B6.2	n/a	chrI 6,917,161	contains similarity to Pfam domain PF01479 S4 domain contains similarity to Interpro domains IPR002942 (RNA-binding S4), IPR001912 (Ribosomal protein S4)
16	F45G2.9	F45G2.9	n/a	chrIII 13,436,244	contains similarity to Pfam domain PF01728 FtsJ-like methyltransferase contains similarity to Interpro domains IPR016448 (23S ribosomal RNA methyltransferase), IPR015507 (Ribosomal RNA methyltransferase J), IPR002877 (Ribosomal RNA methyltransferase RrmJ/FtsJ)
17	VH15N14R.1	VH15N14R.1	n/a	chrI 7,781,895	contains similarity to Aspergillus niger Protein kinase C-like (EC 2.7.1.-).; SW:KPC1_ASPNG
18	itsn-1	Y116A8C.36	n/a	chrIV 17,122,917	tag-11/Y116A8C.36 encodes a homolog of human NCF1, which when mutated leads to chronic granulomatous disease (OMIM:306400).
19	end-3	F58E10.5	n/a	chrV 14,015,253	end-3 encodes a GATA zinc finger protein, paralogous to end-1, that helps specify mesoendodermal (as opposed to mesectodermal) lineages derived from the E blastomere.
20	F10G8.6	F10G8.6	n/a	chrI 10,047,224	F10G8.6 encodes an homolog of S. cerevisiae CFD1 (also known as YIL003W/DRE3), a putative P-loop ATPase conserved in eukaryotes and required in yeast for 4Fe-4S cluster assembly; F10G8.6 is also homologous to yeast NBP35/YGL091C; in C. elegans, F10G8.6 is required for normally rapid growth and maintenance of the germline; F10G8.6 protein was predicted to be mitochondrial on the basis of its phylogenetic profile.
21	sec-3	F52E4.7	n/a	chrX 3,097,634	C. elegans SEC-3 protein ; contains similarity to Danio rerio Exocyst complex component 1.; TR:Q7T2A6
22	ZK1236.5	ZK1236.5	n/a	chrIII 8,431,825	ZK1236.5 encodes a protein with no obvious non-nematode homologs; either ZK1236.9, or ZK1236.5, or both proteins weakly inhibit DHC-1 in vivo; likewise, either ZK1236.5, or ZK1236.9, or both proteins are required in mass RNAi assays for normal osmoregulation and normally rapid growth.
23	str-125	T05E12.1	n/a	chrV 17,075,114	C. elegans STR-125 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	npp-4	Y54E5A.4	n/a	chrI 14,703,902	C. elegans NPP-4 protein; contains similarity to Interpro domains IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
25	F44F1.4	F44F1.4	n/a	chrI 13,264,689	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
26	C27F2.4	C27F2.4	n/a	chrIII 4,959,381	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
27	F54F2.7	F54F2.7	n/a	chrIII 8,806,716	contains similarity to Interpro domain IPR011053 (Single hybrid motif)
28	nol-9	K09B11.2	n/a	chrIV 13,425,891	C. elegans NOL-9 protein; contains similarity to Pfam domain PF08160 NUC156 domain contains similarity to Interpro domains IPR012581 (NUC156), IPR003593 (AAA+ ATPase, core)
29	srd-68	F09C6.7	n/a	chrV 16,901,990	C. elegans SRD-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	T12G3.5	T12G3.5	n/a	chrIV 12,031,705	contains similarity to Drosophila melanogaster Flybase gene name is mRpL51-PA;; FLYBASE:CG13098
31	pssy-2	T27E9.5	n/a	chrIII 13,473,420	C. elegans PSSY-2 protein; contains similarity to Pfam domain PF03034 Phosphatidyl serine synthase contains similarity to Interpro domain IPR004277 (Phosphatidyl serine synthase)
32	C50D2.5	C50D2.5	n/a	chrII 98,671	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1), IPR002343 (Paraneoplastic encephalomyelitis antigen)
33	alr-1	R08B4.2	n/a	chrX 11,123,705	C. elegans ALR-1 protein; contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR013847 (POU), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
34	spr-5	Y40B1B.6	n/a	chrI 13,443,987	spr-5 encodes the C. elegans ortholog of the human histone demethylase LSD1 (lysine-specific demethylase 1) that functions to mediate chromatin remodeling and transcriptional regulation; loss of spr-5 activity can suppress the egg-laying defective (Egl) phenotype of mutations in sel-12/presenilin and derepresses expression of hop-1, which encodes the second C. elegans presenilin, by 20- to 30-fold; in binding assays and yeast two-hybrid experiments, SPR-5 interacts with SPR-1, the C. elegans ortholog of CoREST.
35	F29A7.6	F29A7.6	n/a	chrII 2,752,187	contains similarity to Mus musculus M-phase phosphoprotein 6.; SW:Q9D1Q1
36	nhr-151	C06B8.3	n/a	chrV 15,484,320	C. elegans NHR-151 protein ;
37	ZC196.5	ZC196.5	n/a	chrV 8,731,102	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domain IPR007883 (Protein of unknown function DUF713)
38	nhr-258	C26B2.4	n/a	chrIV 8,045,986	C. elegans NHR-258 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	ceh-49	F17A9.6	n/a	chrV 6,119,282	ceh-49 encodes a divergent ONECUT class CUT homeobox protein with a single N-terminal cut domain; CEH-49 has an atypical tyrosine residue at position 48 of its homeodomain rather than a phenylalanine or tryptophan residue; the cut domain may be a compact DNA-binding domain composed of alpha helices; phylogenetically, CEH-49 is (somewhat distantly) affiliated with CEH-48, Drosophila ONECUT, and mammalian HNF6 proteins; CEH-49 has no obvious function in mass RNAi assays.
40	C37C3.1	C37C3.1	n/a	chrV 7,858,917	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR005448 (Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)
41	C06H2.3	C06H2.3	n/a	chrV 11,128,767	contains similarity to Pfam domains PF02373 (JmjC domain) , PF00583 (Acetyltransferase (GNAT) family) contains similarity to Interpro domains IPR013129 (Transcription factor jumonji), IPR003347 (Transcription factor jumonji/aspartyl beta-hydroxylase), IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
42	D2030.3	D2030.3	n/a	chrI 7,579,667	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
43	syn-13	F36F2.4	n/a	chrI 9,003,016	C. elegans SYN-13 protein; contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region), IPR006012 (Syntaxin/epimorphin, conserved site)
44	eat-5	F13G3.8	n/a	chrI 7,310,218	eat-5 encodes an innexin, expressed in pharyngeal muscle cell groups pm4 and pm5, that is required for synchronized pharyngeal muscle contractions, and for normal electrical connections between pharyngeal muscle cells; EAT-5 forms electrically permeable intercellular channels (gap junctions), with a predicted membrane topology analogous to that of connexins, which affects electrical coupling between different parts of the pharynx and thus affects feeding.
45	F48A11.4	F48A11.4	n/a	chrII 214,905
46	snr-6	Y49E10.15	n/a	chrIII 12,429,334	snr-6 encodes the C. elegans ortholog of the small nuclear ribonucleoprotein E, one of seven subunits of the heptameric Sm complex required for the biogenesis and function of snRNPs that catalyze mRNA splicing; in addition to its predicted role in pre-mRNA processing, SNR-6 activity is essential for embryogenesis and is required for several aspects of germ cell specification including cell division patterns, localization and subcellular distribution of P granules, maintenance of transcriptional quiescence, and expression of the germ lineage-specific proteins PIE-1, GLD-1, and NOS-2; snr-6 is also required for wild-type levels of fertility; immunostaining of adults and embryos using antibodies raised against mammalian Sm proteins suggests that SNR-6 localizes to the nucleus and cytoplasm in many cell types, as well as to P granules in germ cells and their embryonic precursors.
47	F01G12.1	F01G12.1	n/a	chrX 16,395,930	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
48	pfd-5	R151.9	n/a	chrIII 7,198,447	pfd-5 encodes a putative prefoldin 5 subunit, orthologous to human PFDN5 (OMIM:604899), that is required for normal microtubule growth, embryonic and larval viability, fertility, vulval development, and locomotion; PFD-5 is expressed in most, if not all, tissues; pfd-5(RNAi) animals show sterile progeny, larval arrest or lethality, uncoordination, and abnormal body shapes, and pfd-5(RNAi) embryos show a reduced microtubule growth rate.
49	C53C11.1	C53C11.1	n/a	chrX 17,340,978	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
50	F33D11.5	F33D11.5	n/a	chrI 5,836,021	contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)