UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T25B9.6	T25B9.6	0	chrIV 10,759,435	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
2	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
3	clec-79	F47C12.4	n/a	chrIV 3,974,525	C. elegans CLEC-79 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR000538 (Link), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
4	nspa-1	H12D21.1	n/a	chrV 14,886,813	C. elegans NSPA-1 protein ;
5	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
6	F37A8.1	F37A8.1	n/a	chrIII 3,928,769	contains similarity to Rattus norvegicus Myotonic dystrophy kinase-related Cdc42-binding kinase MRCK-beta.; TR:O54875
7	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
8	F35H8.1	F35H8.1	n/a	chrII 9,552,878	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILJ6
9	W03D8.9	W03D8.9	n/a	chrI 2,785,349	contains similarity to Pfam domain PF05884 Caenorhabditis elegans protein of unknown function (DUF856) contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR008574 (Protein of unknown function DUF856, Caenorhabditis species)
10	C49H3.3	C49H3.3	n/a	chrIV 7,924,622	contains similarity to Xenopus tropicalis UPF0446 protein C12orf31 homolog.; SW:Q6NVR5
11	nspa-9	C40H5.1	n/a	chrX 11,739,026	C. elegans NSPA-9 protein ;
12	ZK1128.3	ZK1128.3	n/a	chrIII 10,117,815	contains similarity to Mus musculus 2410017P07Rik protein.; TR:Q9CZE0
13	F20D6.10	F20D6.10	n/a	chrV 8,193,961	contains similarity to Homo sapiens Protein FAM133A; ENSEMBL:ENSP00000318974
14	C10G11.1	C10G11.1	n/a	chrI 6,307,930
15	W01B6.6	W01B6.6	n/a	chrIV 10,081,890	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
16	F36A4.2	F36A4.2	n/a	chrIV 4,271,510	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
17	nspa-5	ZC412.6	n/a	chrV 14,878,391	C. elegans NSPA-5 protein ;
18	C06A5.6	C06A5.6	n/a	chrI 5,984,551
19	F36A4.4	F36A4.4	n/a	chrIV 4,267,908	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
20	nspa-3	ZC412.7	n/a	chrV 14,880,465	C. elegans NSPA-3 protein ;
21	ZK596.2	ZK596.2	n/a	chrIV 10,908,696	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
22	lact-2	ZK945.1	n/a	chrII 10,096,751	lact-2 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
23	B0273.1	B0273.1	n/a	chrIV 5,494,609
24	F35H10.2	F35H10.2	n/a	chrIV 8,329,510
25	ZK666.8	ZK666.8	n/a	chrII 10,492,235	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
26	T08B2.12	T08B2.12	n/a	chrI 6,231,810	contains similarity to Equine herpesvirus 1 Glycoprotein X precursor.; SW:Q6S6W0
27	nspa-8	W06A7.5	n/a	chrV 14,826,947	C. elegans NSPA-8 protein ;
28	ins-7	ZK1251.2	n/a	chrIV 9,682,219	ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.
29	gst-9	R05F9.5	n/a	chrII 4,892,523	gst-9 encodes a predicted glutathione S-transferase; by homology, GST-9 is predicted to play a role in the detoxification of environmental toxins and xenobiotics by transferring glutathione to reactive electrophilic compounds; however, as loss of gst-9 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GST-9 in C. elegans development and/or behavior is not yet known.
30	F47D12.7	F47D12.7	n/a	chrIII 6,294,525	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF00651 (BTB/POZ domain) , PF07646 (Kelch motif) contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000210 (BTB/POZ-like), IPR006652 (Kelch repeat type 1), IPR011333 (BTB/POZ fold), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013069 (BTB/POZ), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
31	Y6E2A.8	Y6E2A.8	n/a	chrV 15,725,749	contains similarity to Encephalitozoon cuniculi UPF0329 protein ECU05_1680/ECU11_0050.; SW:Q8STA9
32	F47B8.6	F47B8.6	n/a	chrV 14,329,569	contains similarity to Drosophila heteroneura Aminopeptidase N (Fragment).; TR:O61534
33	hdl-1	ZK829.2	n/a	chrIV 11,947,905	C. elegans HDL-1 protein; contains similarity to Pfam domain PF00282 Pyridoxal-dependent decarboxylase conserved domain contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR010977 (Aromatic-L-amino-acid decarboxylase), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
34	C04E6.11	C04E6.11	n/a	chrV 5,915,960	contains similarity to Homo sapiens Leucine-rich PPR motif-containing protein, mitochondrial precursor; ENSEMBL:ENSP00000260665
35	msp-32	R05F9.3	n/a	chrII 4,898,889	msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
36	ttr-4	F40F12.1	n/a	chrIII 9,916,526	sdz-17 encodes a protein that contains a transthyretin-like domain; SDZ-17 belongs to a family of apparently nematode-specific proteins whose function is not yet known; early zygotic expression of sdz-17 is dependent upon the SKN-1 transcription factor.
37	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
38	C09B9.2	C09B9.2	n/a	chrIV 5,030,143
39	F45E1.3	F45E1.3	n/a	chrX 7,987,677	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domain IPR005834 (Haloacid dehalogenase-like hydrolase)
40	T05C12.3	T05C12.3	n/a	chrII 8,172,837	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR000565 (DNA topoisomerase, type IIA, subunit B), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
41	B0244.9	B0244.9	n/a	chrIII 5,730,515	contains similarity to Interpro domains IPR005838 (Type III secretion system inner membrane P protein), IPR001865 (Ribosomal protein S2)
42	C41G7.6	C41G7.6	n/a	chrI 9,526,981	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_96, whole genome shotgun sequence.; TR:A0EH68
43	W03D8.5	W03D8.5	n/a	chrI 2,817,203	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
44	K06A5.2	K06A5.2	n/a	chrI 6,468,758	contains similarity to Pfam domain PF05884 Caenorhabditis elegans protein of unknown function (DUF856) contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR008574 (Protein of unknown function DUF856, Caenorhabditis species)
45	C38C3.3	C38C3.3	n/a	chrV 1,497,058
46	R13H9.5	R13H9.5	n/a	chrIV 5,066,321	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
47	ZK1307.3	ZK1307.3	n/a	chrII 9,652,584	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
48	K08F4.3	K08F4.3	n/a	chrIV 10,129,732	contains similarity to Pfam domain PF05753 Translocon-associated protein beta (TRAPB) contains similarity to Interpro domain IPR008856 (Translocon-associated beta)
49	clec-38	T25E12.10	n/a	chrV 16,734,718	C. elegans CLEC-38 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
50	msp-74	F09C12.7	n/a	chrII 5,115,201	msp-74 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.