UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	hlh-3	T24B8.6	1e-59	chrII 9,086,866	hlh-3 encodes a basic helix-loop-helix transcription factor homologous to Drosophila Achaete-scute; in vitro, HLH-3 can heterodimerize, and bind an E-box-containing probe, with HLH-2, the C. elegans E/daughterless ortholog with which it is coexpressed in the nuclei of embryonic neuronal precursors.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	C06C3.3	C06C3.3	n/a	chrII 9,370,697	contains similarity to Pfam domain PF03607 Doublecortin contains similarity to Interpro domain IPR003533 (Doublecortin)
5	C15C7.6	C15C7.6	n/a	chrX 3,169,031	contains similarity to Interpro domain IPR003945 (NADH-plastoquinone oxidoreductase, chain 5)
6	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
7	str-82	B0213.8	n/a	chrV 3,975,447	C. elegans STR-82 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000344 (Nematode chemoreceptor, Sra), IPR003002 (7TM chemoreceptor, subfamily 1)
8	F32B4.1	F32B4.1	n/a	chrI 11,511,408	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
9	fbxa-199	T06E6.3	n/a	chrV 15,398,082	srx-40 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
10	F01G10.9	F01G10.9	n/a	chrIV 10,257,677	contains similarity to Interpro domain IPR000694 (Proline-rich region)
11	F23F1.5	F23F1.5	n/a	chrII 30,845	contains similarity to Interpro domains IPR012310 (ATP dependent DNA ligase, central), IPR017336 (Snurportin-1), IPR002652 (Importin-alpha-like, importin-beta-binding region)
12	nhr-78	F36A4.14	n/a	chrIV 4,276,441	C. elegans NHR-78 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
13	K02D10.5	K02D10.5	n/a	chrIII 8,777,270	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domain IPR000727 (Target SNARE coiled-coil region)
14	dpm-1	Y66H1A.2	n/a	chrIV 447,058	dpm-1 encodes a putative catalytic subunit of dolichol phosphate mannosyltransferase, orthologous to budding yeast and human DPM1 (OMIM:603503, mutated in congenital disorder of glycosylation type Ie); in mass RNAi assays, DPM-1 is required for embryonic viability and proper cortical motion in the early embryo.
15	spp-19	K04A8.9	n/a	chrV 6,559,648	C. elegans SPP-19 protein; contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
16	F58G1.6	F58G1.6	n/a	chrII 12,941,277	contains similarity to Pfam domain PF02752 Arrestin (or S-antigen), C-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal)
17	M02G9.2	M02G9.2	n/a	chrII 10,323,075	contains similarity to Pfam domains PF06493 (Protein of unknown function (DUF1096)) , PF02363 (Cysteine rich repeat) (8)contains similarity to Interpro domains IPR009475 (Protein of unknown function DUF1096), IPR003566 (T-cell surface glycoprotein CD5)
18	M04F3.2	M04F3.2	n/a	chrI 4,766,635	contains similarity to Bradyrhizobium japonicum 30S ribosomal protein S6.; SW:Q89MW3
19	sdc-2	C35C5.1	n/a	chrX 11,528,006	The sdc-2 gene encodes a protein that represses transcription of X chromosomes to achieve dosage compensation, and that also represses the male sex-determination gene her-1 to elicit hermaphrodite differentiation.
20	vps-32.2	C37C3.3	n/a	chrV 7,850,487	C. elegans VPS-32.2 protein; contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
21	T22B11.2	T22B11.2	n/a	chrIV 4,690,180	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
22	rpb-4	F43E2.2	n/a	chrII 7,374,771	C. elegans RPB-4 protein; contains similarity to Pfam domain PF03874 RNA polymerase Rpb4 contains similarity to Interpro domains IPR010997 (HRDC-like), IPR005574 (RNA polymerase II, Rpb4), IPR006590 (RNA polymerase II, Rpb4, core)
23	H10E21.2	H10E21.2	n/a	chrIII 10,398	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
24	AH9.3	AH9.3	n/a	chrX 2,259,841	contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
25	F41C3.4	F41C3.4	n/a	chrII 4,740,995	contains similarity to Pfam domain PF04178 Got1-like family contains similarity to Interpro domain IPR007305 (Got1-like protein)
26	ZK185.2	ZK185.2	n/a	chrIV 4,539,155	ZK185.2 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK185.2 is predicted to transport Mg(2+) into cells; ZK185.2 is paralogous to K07H8.2 and ZK1053.6, and has no obvious function in mass RNAi assays.
27	hsr-9	T05F1.6	n/a	chrI 9,628,707	hsr-9 encodes a protein containing a BRCT (BRCA 1 C terminus) domain that is found in proteins that regulate the cell cycle checkpoint in response to DNA damage; HSR-9 activity is required for a normal response to DNA damage caused by gamma-irradiation; loss of HSR-9 function via RNA-mediated interference after gamma-irradiation results in defects in mitotic cell cycle arrest, reduction of apoptosis of pachytene nuclei, and radiation sensitivity of progeny; the expression pattern and subcellular localization of HSR-9 are not yet known.
28	W10G11.3	W10G11.3	n/a	chrII 3,562,186	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
29	asf-1	F10G7.3	n/a	chrII 4,702,628	C. elegans ASF-1 protein; contains similarity to Pfam domain PF04729 Anti-silencing protein, ASF1-like contains similarity to Interpro domains IPR006818 (Anti-silencing protein, ASF1-like), IPR017282 (Histone deposition protein Asf1)
30	pph-6	C34C12.3	n/a	chrIII 3,464,667	C. elegans PPH-6 protein; contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
31	lin-12	R107.8	n/a	chrIII 9,065,726	The lin-12 gene encodes a member of the Notch/LIN-12/glp-1 transmembrane receptor family that affects cell fate specification events during development, notably including the anchor cell, secondary vulval precursor cells, and the embryonic ABplp lineage; its expression is dynamic, including Z1.ppp and Z4.aaa, ABplaa descendants, ABplpa descendants, and the intestinal primordium.
32	Y44E3A.3	Y44E3A.3	n/a	chrI 3,318,281	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR015467 (Thioredoxin family), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
33	K05F6.4	K05F6.4	n/a	chrII 1,544,461	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
34	F49C12.12	F49C12.12	n/a	chrIV 9,320,583	contains similarity to Homo sapiens RNase K; VG:OTTHUMP00000182776
35	C47D12.8	C47D12.8	n/a	chrII 11,700,677	C47D12.8 encodes an ortholog of the DNA repair protein XPF/ERCC4, which when mutated in humans leads to xeroderma pigmentosum (complementation group F; OMIM:133520); C47D12.8(RNAi) animals are hypersensitive to ultraviolet radiation, with increased germ cell apoptosis and embryonic lethality; C47D12.8 protein interacts with F10G8.7 (an ERCC1 ortholog) in yeast two-hybrid assays; C47D12.8 is expressed broadly in both embryonic and postembryonic animals, and is required for embryonic development; C47D12.8 is upregulated in dauers, and shares an operon with kel-1 and VF13D12L.3.
36	C23H5.7	C23H5.7	n/a	chrIV 2,107,829	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000595 (Cyclic nucleotide-binding), IPR014710 (RmlC-like jelly roll fold)
37	F25B4.4	F25B4.4	n/a	chrV 5,685,274
38	ZC190.7	ZC190.7	n/a	chrV 8,686,461
39	W06D12.1	W06D12.1	n/a	chrV 17,736,716	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
40	nhr-215	T07C5.4	n/a	chrX 12,699,419	C. elegans NHR-215 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	btb-5	W05G11.5	n/a	chrIII 60,257	C. elegans BTB-5 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
42	Y51A2D.15	Y51A2D.15	n/a	chrV 18,602,136	contains similarity to Mus musculus Girdin (Girders of actin filament) (Coiled-coil domain-containingsprotein 88A) (Akt phosphorylation enhancer) (APE) (Hook-relatedsprotein 1) (HkRP1) (G alpha-interacting vesicle-associated protein)s(GIV).; SW:Q5SNZ0
43	Y75B8A.5	Y75B8A.5	n/a	chrIII 12,116,403	contains similarity to Interpro domain IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal)
44	K06G5.3	K06G5.3	n/a	chrX 14,221,334	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
45	F58B3.6	F58B3.6	n/a	chrIV 11,637,391	contains similarity to Pfam domains PF04836 (Interferon-related protein conserved region) , PF05004 (Interferon-related developmental regulator (IFRD)) contains similarity to Interpro domains IPR007701 (Interferon-related developmental regulator), IPR006921 (Interferon-related protein conserved region), IPR016024 (Armadillo-type fold)
46	his-55	F54E12.1	n/a	chrIV 11,338,029	his-55 encodes an H3 histone; by homology, HIS-55 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-55 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
47	str-28	F25E5.12	n/a	chrV 7,472,264	C. elegans STR-28 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	C56G2.15	C56G2.15	n/a	chrIII 6,367,144	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase), IPR008125 (Streptothricin acetyltransferase)
49	H14E04.1	H14E04.1	n/a	chrIII 2,404,160	contains similarity to Pfam domains PF02353 (Cyclopropane-fatty-acyl-phospholipid synthase) , PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) , PF01209 (ubiE/COQ5 methyltransferase family) contains similarity to Interpro domains IPR004033 (UbiE/COQ5 methyltransferase), IPR003333 (Cyclopropane-fatty-acyl-phospholipid synthase), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
50	C18G1.6	C18G1.6	n/a	chrV 4,752,187	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)