UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-222	T24A6.11	0	chrV 3,542,513	C. elegans NHR-222 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
2	C01G5.3	C01G5.3	n/a	chrIV 6,537,601	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	Y45F10B.9	Y45F10B.9	n/a	chrIV 13,597,410	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000533 (Tropomyosin)
5	C14E2.3	C14E2.3	n/a	chrX 1,811,106
6	R05H5.4	R05H5.4	n/a	chrII 10,198,961	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
7	F25B3.2	F25B3.2	n/a	chrV 9,578,510	contains similarity to Lactococcus lactis Oligopeptide transport system permease protein oppC.; SW:OPPC_LACLA
8	srg-21	Y25C1A.9	n/a	chrII 3,089,880	C. elegans SRG-21 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
9	ttr-6	T28B4.3	n/a	chrX 6,596,773	C. elegans TTR-6 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
10	ggr-1	C09G5.1	n/a	chrII 10,698,711	ggr-1 encodes a predicted member of the GABA/ glycine receptor family of ligand-gated chloride channels that affects thermotaxis; expressed in AIB, PVR, PVQ, AVH, and SMDV neurons and in some motor neurons in the ventral cord, and in the egg-laying muscles.
11	K10D6.3	K10D6.3	n/a	chrV 11,201,218	contains similarity to Homo sapiens HMG-BOX transcription factor BBX; ENSEMBL:ENSP00000319742
12	fbxb-1	T26H2.1	n/a	chrV 19,240,953	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
13	abt-6	F56F4.6	n/a	chrI 6,139,832	F56F4.6 encodes a protein that contains an ATP-binding cassette (ABC) that is most closely related to that of the ABCA subfamily of ABC transport proteins; as the product of F56F4.6 lacks a predicted transmembrane domain, and as loss of F56F4.6 activity via RNAi results in no obvious defects, the precise role of this gene in C. elegans development and/or behavior is not yet known.
14	R06C1.2	R06C1.2	n/a	chrI 11,920,861	contains similarity to Pfam domain PF00348 Polyprenyl synthetase contains similarity to Interpro domains IPR000092 (Polyprenyl synthetase), IPR008949 (Terpenoid synthase)
15	T08G11.2	T08G11.2	n/a	chrI 8,919,920	T08G11.2 encodes a nematode-specific sperm protein, required for a normally high ovulation rate, that interacts with EGL-32; despite not being EGL-32, and although T08G11.2(tm336) complements egl-32(n155), T08G11.2 can partially rescue egl-32 mutants when expressed transgenically, implying that T08G11.2 can be a nonorthologous replacement for EGL-32 function in vivo; T08G11.2 has an SH2 motif, but this motif lacks a critical arginine residue; T08G11.2 has no obvious non-nematode homologs, but is paralogous to four other C. elegans proteins (B0207.11, F42G4.6, F44F4.10, and Y81G3A.1); T08G11.2(tm336) hermaphrodites have a lowered ovulation rate (and thus a lowered rate of egg-laying), retaining significantly fewer eggs than wild-type, yet also retaining late-stage embryos; T08G11.2 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs; T08G11.2 expression is strongly enriched in spermatogenesis.
16	Y57G11C.8	Y57G11C.8	n/a	chrIV 14,782,524	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000302919
17	C17D12.5	C17D12.5	n/a	chrI 11,586,755	contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like)
18	C23H4.6	C23H4.6	n/a	chrX 12,238,124	contains similarity to Pfam domain PF02463 RecF/RecN/SMC N terminal domain contains similarity to Interpro domain IPR003395 (RecF/RecN/SMC protein, N-terminal)
19	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
20	ZC376.8	ZC376.8	n/a	chrV 14,180,879	contains similarity to Pfam domain PF03057 Protein of unknown function contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR015425 (Actin-binding FH2), IPR004296 (Protein of unknown function DUF236), IPR000694 (Proline-rich region)
21	ZK1010.8	ZK1010.8	n/a	chrIII 12,998,222	contains similarity to Homo sapiens BRG1-binding protein ELD/OSA1 isoform 1; TR:Q8IZY8
22	F49D11.4	F49D11.4	n/a	chrI 10,914,398	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
23	ZK1098.6	ZK1098.6	n/a	chrIII 9,527,820	ZK1098.6 encodes a coiled-coil protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
24	srg-46	F32H5.5	n/a	chrV 13,364,203	C. elegans SRG-46 protein ;
25	rsr-1	F28D9.1	n/a	chrI 11,179,945	C. elegans RSR-1 protein; contains similarity to Pfam domain PF01480 PWI domain contains similarity to Interpro domains IPR002483 (Splicing factor PWI), IPR000694 (Proline-rich region), IPR005819 (Histone H5), IPR002185 (Dopamine D4 receptor)
26	F14D2.9	F14D2.9	n/a	chrII 3,354,397	contains similarity to Xenopus laevis Putative uncharacterized protein.; TR:Q08AY0
27	scl-23	B0545.3	n/a	chrIV 88,065	C. elegans SCL-23 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR014044 (SCP-like extracellular)
28	Y56A3A.2	Y56A3A.2	n/a	chrIII 11,856,255	contains similarity to Pfam domain PF02163 Peptidase family M50 contains similarity to Interpro domains IPR008915 (Peptidase M50), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001193 (Peptidase M50, mammalian sterol-regulatory element binding protein)
29	F34H10.3	F34H10.3	n/a	chrX 9,634,393	contains similarity to Anabaena sp Hypothetical protein Asr1307.; TR:Q8YXA8
30	C10G11.10	C10G11.10	n/a	chrI 6,305,695
31	T09B4.3	T09B4.3	n/a	chrI 6,177,087
32	ZK1086.3	ZK1086.3	n/a	chrX 13,791,278	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
33	dsl-5	F58B3.8	n/a	chrIV 11,620,190	dsl-5 encodes a putative secreted protein with single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-5 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
34	F11D5.5	F11D5.5	n/a	chrX 3,302,988	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
35	ZK1248.9	ZK1248.9	n/a	chrII 5,814,835	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
36	W02B8.4	W02B8.4	n/a	chrII 13,922,543	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
37	F41F3.1	F41F3.1	n/a	chrV 4,655,174
38	C25G4.8	C25G4.8	n/a	chrIV 12,461,585	contains similarity to Pfam domain PF06887 Protein of unknown function (DUF1265) contains similarity to Interpro domain IPR009676 (Protein of unknown function DUF1265)
39	Y116A8A.7	Y116A8A.7	n/a	chrIV 16,830,442	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
40	K05F1.5	K05F1.5	n/a	chrII 5,791,755	contains similarity to Pfam domain PF01551 Peptidase family M23 contains similarity to Interpro domains IPR016047 (Peptidase M23), IPR008663 (Leukocyte cell-derived chemotaxin 2), IPR011055 (Duplicated hybrid motif)
41	Y116A8C.19	Y116A8C.19	n/a	chrIV 17,039,245	Y116A8C.19 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y116A8C.19 is predicted to function as an RNA-binding protein.
42	F23B12.1	F23B12.1	n/a	chrV 14,429,754	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
43	F54D1.1	F54D1.1	n/a	chrIV 11,262,424	contains similarity to Interpro domain IPR004087 (K Homology)
44	nas-5	T23H4.3	n/a	chrI 9,887,167	nas-5 encodes an astacin-like metalloprotease; loss of nas-5 activity in an RNAi hypersensitive strain results in axon guidance defects, including a failure of DD/VD motoneuron commissures to reach the dorsal cord, defasciculation of the dorsal nerve cord, and midline crossing defects in the ventral nerve cord.
45	F57A8.6	F57A8.6	n/a	chrV 10,072,890	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domain IPR002593 (Protein of unknown function DX)
46	T06E4.5	T06E4.5	n/a	chrV 9,631,723	contains similarity to Interpro domains IPR001046 (Natural resistance-associated macrophage protein), IPR001266 (Ribosomal protein S19e)
47	wht-3	C16C10.12	n/a	chrIII 4,149,469	C16C10.12 encodes an ATP-binding cassette (ABC) transporter; C16C10.12 activity is required for efficient RNA interference (RNAi) of a germline-expressed target, pop-1.
48	Y56A3A.6	Y56A3A.6	n/a	chrIII 11,874,979	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region), IPR002951 (Atrophin)
49	str-64	T28A11.1	n/a	chrV 3,283,924	C. elegans STR-64 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	snf-8	ZK829.10	n/a	chrIV 11,967,123	C. elegans SNF-8 protein; contains similarity to Pfam domain PF00209 Sodium:neurotransmitter symporter family contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR004354 (Meiotic recombination protein rec114)