UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T23B3.2	T23B3.2	2e-35	chrI 6,716,467	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	ced-8	F08F1.5	n/a	chrX 8,415,405	The ced-8 gene encodes a homolog of the human putative membrane transporter XK; ced-8 is required for apoptosis to occur with normal speed during embryonic development.
4	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
5	F35E8.10	F35E8.10	n/a	chrV 15,919,877	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
6	F55C9.11	F55C9.11	n/a	chrV 19,307,376	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
7	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
8	com-1	C44B9.5	n/a	chrIII 10,898,988	com-1 encodes an ortholog of budding yeast Sae2p, Arabidopsis AtCOM1, and human RBBP8 (CTIP; OMIM:604124) and C20orf151; like its yeast ortholog, COM-1 is probably required for completing meiotic recombination; meiotic chromosomes in com-1 mutants pair normally, but form irregular chromatin aggregates instead of diakinesis bivalents; while meiotic DNA double-strand breaks (DSBs) are formed, they appear to persist or undergo improper repair, with numerous chromosomal fragments being revealed by REC-8 depletion; conversely, suppression of DSBs by a spo-11 mutation also suppresses the diakinetic com-1 phenotype, and suppression by mre-11 increases com-1 mutant fertility; despite the presence of DSBs, the recombination protein RAD-51, which is known to associate with single-stranded (ss) DNA flanking DSBs, does not localize to meiotic chromosomes in com-1 mutants; exposure of com-1 mutants to gamma-radiation, however, induces RAD-51 foci, which suggests that the failure of RAD-51 to load is specific to meiotic (SPO-11-generated) DSBs; these data suggest that COM-1 helps generate ssDNA tails upon which RAD-51 can bind, after which RAD-51 migrates to homologous DNA tracts and triggers meiotic recombination; com-1 mutants grow and live normally (possibly because of maternally contributed COM-1) but are sterile; the C-terminal-most ~100 residues of COM-1 are strongly conserved, while COM-1's N-terminal ~400 residues have low sequence complexity.
9	col-97	ZK1010.7	n/a	chrIII 12,993,066	col-97 encodes a cuticular collagen; loss of col-97 activity via large-scale RNAi screens results in defects in body morphology and locomotion.
10	F08D12.13	F08D12.13	n/a	chrII 2,795,880
11	cut-6	M142.2	n/a	chrIII 10,913,915	C. elegans CUT-6 protein; contains similarity to Pfam domains PF00100 (Zona pellucida-like domain) , PF00092 (von Willebrand factor type A domain) contains similarity to Interpro domains IPR001507 (Endoglin/CD105 antigen), IPR002035 (von Willebrand factor, type A)
12	btb-10	K02E7.9	n/a	chrII 1,060,263	C. elegans BTB-10 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
13	C29A12.6	C29A12.6	n/a	chrV 10,849,822	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
14	Y75B8A.18	Y75B8A.18	n/a	chrIII 12,226,253	contains similarity to Homo sapiens Splice isoform 1 of Q03001 Bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8; ENSEMBL:ENSP00000281662
15	C30G12.3	C30G12.3	n/a	chrII 7,275,917
16	F48F7.3	F48F7.3	n/a	chrX 13,964,989	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
17	T22D1.6	T22D1.6	n/a	chrIV 6,899,771
18	E03H4.5	E03H4.5	n/a	chrI 12,414,766	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
19	F21D12.2	F21D12.2	n/a	chrII 7,318,858
20	C33E10.1	C33E10.1	n/a	chrX 17,305,742	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
21	fbxb-19	F58E1.9	n/a	chrII 1,688,706	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
22	T22C8.4	T22C8.4	n/a	chrII 8,623,075	contains similarity to Interpro domains IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
23	dgn-3	F07G6.1	n/a	chrX 1,730,834	C. elegans DGN-3 protein ;
24	F36H5.4	F36H5.4	n/a	chrII 1,762,375
25	W06D11.2	W06D11.2	n/a	chrX 12,296,301
26	F31D4.5	F31D4.5	n/a	chrV 20,851,509	contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR010997 (HRDC-like), IPR011993 (Pleckstrin homology-type)
27	Y57A10C.1	Y57A10C.1	n/a	chrII 12,411,984	contains similarity to Macaca mulatta Thyrotropin receptor (Fragment).; TR:Q8HY53
28	pin-2	F07C6.1	n/a	chrIV 12,794,963	pin-2 encodes a LIM domain-containing protein that, along with UNC-97, comprises the two C. elegans members of the PINCH family of predicted adapter proteins; based upon its similarity to Drosophila and vertebrate members of the PINCH family, PIN-2 is predicted to play a role in regulation of cell morphology, motility, and survival, but as loss of pin-2 via large-scale RNAi results in no obvious defects, the precise role of PIN-2 in C. elegans development and/or behavior is not yet known; a PIN-2::GFP fusion protein is first expressed in embryos just prior to hatching and in early larvae is seen in several neurons, including the PVT neuron, and in intestinal cells; during postembryonic development, neuronal expression continues, whereas intestinal expression gradually declines; PIN-2 localizes to the cytoplasm and to the nucleus, and in neurons, is seen in axonal processes and varicosities.
29	C46A5.4	C46A5.4	n/a	chrIV 7,752,034	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal)
30	lgc-9	C04C3.2	n/a	chrIV 3,417,455	C. elegans LGC-9 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
31	gur-5	ZK622.2	n/a	chrII 5,287,091	C. elegans GUR-5 protein ;
32	srh-122	R08H2.5	n/a	chrV 15,377,228	C. elegans SRH-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	fbxb-98	C16C4.6	n/a	chrII 1,863,210	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
34	nhr-148	C03G6.10	n/a	chrV 7,342,974	C. elegans NHR-148 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
35	F55C5.6	F55C5.6	n/a	chrV 12,280,460	contains similarity to Pfam domain PF01593 Flavin containing amine oxidoreductase contains similarity to Interpro domains IPR000759 (Adrenodoxin reductase), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding)
36	T05C3.2	T05C3.2	n/a	chrV 5,498,362	The T05C3.2 gene encodes a protein that may be involved in apoptosis.
37	fbxb-25	F58E1.2	n/a	chrII 1,684,456	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
38	bath-9	Y49F6C.3	n/a	chrII 3,377,880	C. elegans BATH-9 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR010916 (TonB box, conserved site), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
39	F54E2.2	F54E2.2	n/a	chrV 2,796,653	contains similarity to Pfam domain PF00095 WAP-type (Whey Acidic Protein) 'four-disulfide core' contains similarity to Interpro domain IPR008197 (Whey acidic protein, 4-disulphide core)
40	C24H12.7	C24H12.7	n/a	chrII 420,597	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
41	hot-6	C13G3.2	n/a	chrV 11,021,972	C. elegans HOT-6 protein ;
42	F38E9.4	F38E9.4	n/a	chrX 16,452,168
43	srh-297	C17F4.4	n/a	chrII 3,229,698	C. elegans SRH-297 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR006084 (DNA repair protein (XPGC)/yeast Rad), IPR003002 (7TM chemoreceptor, subfamily 1)
44	ces-2	ZK909.4	n/a	chrI 14,963,425	ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V).
45	ZC239.2	ZC239.2	n/a	chrII 3,218,443	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
46	srh-49	C10G11.4	n/a	chrI 6,298,750	C. elegans SRH-49 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	F34D6.1	F34D6.1	n/a	chrII 2,680,190	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	C01B7.3	C01B7.3	n/a	chrV 8,783,769
49	mdt-22	ZK970.3	n/a	chrII 10,301,446	C. elegans MDT-22 protein; contains similarity to Pfam domain PF06179 Surfeit locus protein 5 contains similarity to Interpro domain IPR009332 (Surfeit locus 5)
50	srw-57	F36G9.1	n/a	chrV 15,954,286	C. elegans SRW-57 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)