UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ptr-16	T21H3.2	0	chrV 1,172,902	ptr-16 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-16 is partially required for normal molting from L2 to L3 larval stages; however, PTR-16 and PTR-1 together are strongly required for both molting and viability, with double ptr-1/-16 RNAi animals showing pronounced molting defects and lethality; PTR-16 is also required for normal growth to full size and locomotion.
2	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
3	pax-3	F27E5.2	n/a	chrII 10,149,568	pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes).
4	mef-2	W10D5.1	n/a	chrI 9,097,999	mef-2 encodes a transcription factor that is the sole C. elegans member of the MEF2 subgroup of MADS box transcription factors; loss of mef-2 activity does not result in a strong visible phenotype, although mef-2 mutant adults are slightly dumpy (Dpy); in vitro, MEF-2 is able to bind a consensus MEF2 DNA binding site and interact with the class II histone deacetylase encoded by C10E2.3 (hda-4/hda-7); mef-2 mRNA is detected at all stages of development and expression of mef-2 reporter gene fusions begins in neurons during late embryogenesis and continues in all tissues throughout postembryonic development; mef-2 mutations do not appear to interact with mutations in other myogenic factors such as hlh-1, hlh-8, pha-1, and unc-120.
5	C07D10.1	C07D10.1	n/a	chrII 7,399,714	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
6	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
7	C31B8.4	C31B8.4	n/a	chrV 2,897,526	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
8	sra-37	T21H8.2	n/a	chrX 13,892,086	C. elegans SRA-37 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
9	C12D5.3	C12D5.3	n/a	chrV 7,676,566	contains similarity to Interpro domain IPR002194 (Chaperonin TCP-1, conserved site)
10	sre-23	ZK265.5	n/a	chrI 8,257,642	C. elegans SRE-23 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
11	T28F4.4	T28F4.4	n/a	chrI 7,488,371	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.05a.; TR:Q8IHI4
12	C34C6.3	C34C6.3	n/a	chrII 8,692,922	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR000585 (Hemopexin), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR005018 (DOMON related), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
13	C05D11.13	C05D11.13	n/a	chrIII 6,443,485	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
14	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	xtr-1	F54F7.4	n/a	chrX 11,852,038	xtr-1 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
16	Y57G11C.20	Y57G11C.20	n/a	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
17	F38B6.2	F38B6.2	n/a	chrX 6,699,255	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
18	F35E2.9	F35E2.9	n/a	chrI 11,724,844	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
19	fbxa-162	C08E3.5	n/a	chrII 1,608,500	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
20	nhr-139	C33G8.8	n/a	chrV 6,986,930	C. elegans NHR-139 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	nhr-19	E02H1.7	n/a	chrII 9,601,747	C. elegans NHR-19 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
22	nekl-2	ZC581.1	n/a	chrI 6,664,152	nekl-2 encodes a putative serine/threonine protein kinase orthologous to Aspergillus nidulans nimA and human NEK8 (OMIM:609799), and paralogous to C. elegans D1044.3, D1044.8, F19H6.1, and Y39G10AR.3; nekl-2 interacts with two or more components of the EGF/RAS signalling pathway, and is required for such signalling in vulval development.
23	col-43	ZC513.8	n/a	chrV 8,050,298	col-43 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens.
24	zig-2	F42F12.2	n/a	chrX 12,340,922	zig-2 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-2::gfp reporter fusion is expressed in the PVT interneuron and weakly in 4-6 additional head neurons.
25	srx-84	F35B12.1	n/a	chrV 11,599,872	C. elegans SRX-84 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	tag-199	F45E4.4	n/a	chrIV 7,612,783	C. elegans TAG-199 protein ; contains similarity to Trypanosoma brucei Putative uncharacterized protein.; TR:Q4GZ45
27	C32F10.4	C32F10.4	n/a	chrI 5,809,249
28	F57C7.4	F57C7.4	n/a	chrX 10,585,230	contains similarity to Interpro domain IPR008972 ()
29	C36C5.12	C36C5.12	n/a	chrV 3,158,933	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
30	F23C8.11	F23C8.11	n/a	chrI 2,450,235	contains similarity to Interpro domain IPR008880 (Trigger factor, C-terminal, bacterial)
31	C11D2.1	C11D2.1	n/a	chrIV 6,191,401
32	Y37D8A.6	Y37D8A.6	n/a	chrIII 12,857,304	contains similarity to Interpro domains IPR006629 (LPS-induced tumor necrosis factor alpha factor), IPR013032 (EGF-like region, conserved site)
33	str-171	T01G5.5	n/a	chrV 15,131,482	C. elegans STR-171 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	F46H5.5	F46H5.5	n/a	chrX 7,256,401
35	clec-59	ZK666.5	n/a	chrII 10,478,656	C. elegans CLEC-59 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
36	clec-249	Y51A2A.7	n/a	chrV 18,304,784	C. elegans CLEC-249 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	nhr-18	F44C8.3	n/a	chrV 2,228,092	The nhr-18 gene encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain; the human homolog of nhr-18, CYP21, when mutated leads to congenital adrenal hyperplasia (OMIM:201910).
38	C32D5.1	C32D5.1	n/a	chrII 6,344,783
39	srx-56	C03G6.2	n/a	chrV 7,374,979	C. elegans SRX-56 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
40	ZK337.2	ZK337.2	n/a	chrI 14,977,996	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
41	col-37	ZK863.2	n/a	chrV 12,167,206	col-37 encodes a cuticle collagen.
42	F26D11.2	F26D11.2	n/a	chrV 7,960,124
43	nhr-191	F55D12.3	n/a	chrI 7,896,919	C. elegans NHR-191 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	scl-2	F49E11.10	n/a	chrIV 13,058,350	C. elegans SCL-2 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
45	srw-33	T26H5.5	n/a	chrV 15,450,551	C. elegans SRW-33 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000276 (GPCR, rhodopsin-like)
46	srd-26	T02B5.4	n/a	chrV 14,162,174	C. elegans SRD-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	glt-5	Y53C12A.2	n/a	chrII 9,707,756	glt-5 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
48	C06A5.6	C06A5.6	n/a	chrI 5,984,551
49	K07C11.3	K07C11.3	n/a	chrV 8,207,597	contains similarity to Interpro domains IPR008993 (TIMP-like, OB-fold), IPR001820 (Proteinase inhibitor I35, tissue inhibitor of metalloproteinase), IPR001134 (Netrin, C-terminal)
50	fbxb-48	F45C12.13	n/a	chrII 1,718,632	C. elegans FBXB-48 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)