UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pqn-67	T16G1.1	2e-149	chrV 12,926,198	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
2	Y116A8B.5	Y116A8B.5	n/a	chrIV 17,228,490	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
3	C34E7.4	C34E7.4	n/a	chrX 12,933,527	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
4	asf-1	F10G7.3	n/a	chrII 4,702,628	C. elegans ASF-1 protein; contains similarity to Pfam domain PF04729 Anti-silencing protein, ASF1-like contains similarity to Interpro domains IPR006818 (Anti-silencing protein, ASF1-like), IPR017282 (Histone deposition protein Asf1)
5	C24A3.4	C24A3.4	n/a	chrX 8,993,472	contains similarity to Pfam domain PF02515 CoA-transferase family III contains similarity to Interpro domains IPR016160 (Aldehyde dehydrogenase, conserved site), IPR003673 (CoA-transferase family III)
6	str-149	Y32B12B.5	n/a	chrV 16,574,182	C. elegans STR-149 protein ;
7	F52G3.5	F52G3.5	n/a	chrX 16,974,629	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR003582 (Metridin-like ShK toxin)
8	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
9	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
10	F58F6.5	F58F6.5	n/a	chrIV 1,343,974	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domain IPR006874 (Protein of unknown function DUF621)
11	T20B6.3	T20B6.3	n/a	chrIII 2,899,911	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein)
12	C07G1.7	C07G1.7	n/a	chrIV 8,211,372
13	F13D2.4	F13D2.4	n/a	chrX 11,188,488	contains similarity to Homo sapiens Isoform 3 of CD109 antigen precursor; HI:HIT000020743
14	F46C8.1	F46C8.1	n/a	chrX 7,550,722
15	C44B12.3	C44B12.3	n/a	chrIV 1,105,091
16	T07F10.6	T07F10.6	n/a	chrV 12,865,830	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
17	F43C1.5	F43C1.5	n/a	chrIII 4,229,767	contains similarity to Pfam domain PF02845 CUE domain contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR009060 (UBA-like)
18	ZC328.2	ZC328.2	n/a	chrI 6,389,348	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
19	ram-5	T24C2.1	n/a	chrX 14,553,138	ram-5 encodes a novel transmembrane protein; during male tail development, ram-5 activity is required in ray structural cells for proper sensory ray morphogenesis; a RAM-5::GFP fusion protein is expressed in all of the ray structural cells of the male tail, as well as additional sensory support cells in both hermaphrodites and males, including those of the inner labial sensilla as well as the ADE, PDE, and phasmid socket cells.
20	fbxa-130	F42A6.8	n/a	chrIV 3,340,450	C. elegans FBXA-130 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
21	ugt-53	T03D3.1	n/a	chrV 2,850,684	C. elegans UGT-53 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domains IPR002416 (Bacterial general secretion pathway protein H), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
22	ctg-1	H06O01.3	n/a	chrI 7,007,341	C. elegans CTG-1 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
23	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
24	W03F11.5	W03F11.5	n/a	chrI 2,217,759	n/a
25	fbxa-199	T06E6.3	n/a	chrV 15,398,082	srx-40 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
26	C31H2.4	C31H2.4	n/a	chrX 5,157,381	C31H2.4 encodes a possible 4-hydroxyphenylpyruvate dioxygenase, orthologous to human HPDL/GLOXD1, and paralogous to HPD-1 and human HPD (OMIM:609695, mutated in tyrosinemia type III); C31H2.4 has no obvious function in mass RNAi experiments.
27	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
28	dsl-2	W09G12.1	n/a	chrIV 1,203,808	dsl-2 encodes a putative transmembrane protein whose extracellular domain has single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-2 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
29	K10C9.3	K10C9.3	n/a	chrV 1,064,729	contains similarity to Pfam domain PF00445 Ribonuclease T2 family contains similarity to Interpro domain IPR001568 (Ribonuclease T2)
30	C09F5.1	C09F5.1	n/a	chrIII 660,714
31	lrx-1	T04H1.6	n/a	chrV 12,253,997	lrx-1 encodes a protein that contains four class A low-density lipoprotein receptor domains.
32	tra-3	LLC1.1	n/a	chrIV 14,440,241	tra-3 encodes an atypical calpain regulatory protease that lacks calcium-binding EF hand domains; during development, TRA-3 likely promotes female development in XX hermaphrodites by cleaving the membrane-associated TRA-2A protein to generate a TRA-2 peptide likely to have feminizing activity; in addition, TRA-3 is one of several proteases that mediate necrotic cell death during neurodegeneration.
33	btb-12	ZC204.3	n/a	chrII 1,655,685	C. elegans BTB-12 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
34	M163.2	M163.2	n/a	chrX 14,497,680	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
35	let-19	K08F8.6	n/a	chrII 8,776,425	The let-19 gene encodes a protein related to human TRAP240 (thyroid hormone receptor-associated protein 240, OMIM:300182), a transcriptional co-activation complex subunit conserved in yeast, Drosophila, and humans; LET-19 is required for proper asymmetric cell divisions and cell fusions regulated by LIN-44/Wnt and LIN-17/frizzled, as well as for proper development of secondary vulval cell fates as regulated by Notch signaling.
36	srh-250	C49D10.3	n/a	chrII 3,879,253	C. elegans SRH-250 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	M153.2	M153.2	n/a	chrX 12,152,642	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF05978 (Eukaryotic protein of unknown function (DUF895)) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
38	Y38H6C.4	Y38H6C.4	n/a	chrV 20,500,386	contains similarity to Mus musculus Similar to hypothetical protein FLJ21522 (Epidermal growth factorsreceptor pathway substrate 8 related protein 3).; TR:Q91WL0
39	F08D12.12	F08D12.12	n/a	chrII 2,784,540	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000024537
40	sph-1	F42G8.11	n/a	chrIV 8,132,914	sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain.
41	R07B7.8	R07B7.8	n/a	chrV 12,082,679	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
42	T03D8.2	T03D8.2	n/a	chrV 20,833,812	contains similarity to Pfam domain PF00164 Ribosomal protein S12 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR006032 (Ribosomal protein S12/S23), IPR012340 (Nucleic acid-binding, OB-fold), IPR005679 (Ribosomal protein S12, bacterial-type)
43	glc-4	C27H5.8	n/a	chrII 7,173,524	glc-4 encodes a predicted glutamate-gated chloride channel that affects ivermectin sensitivity and reversal behavior and genetically interacts with avr-14; expressed in neurons.
44	str-144	C09H5.5	n/a	chrV 8,071,381	C. elegans STR-144 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	rgs-6	C41G11.3	n/a	chrX 5,724,513	rgs-6 encodes a regulator of G protein signaling; by homology, RGS-6 is predicted to function as a GTPase-activating protein that binds G protein alpha subunits and negatively regulates heterotrimeric G protein signaling; loss of rgs-6 activity via RNAi or a deletion mutation results in no obvious defects, and likewise, rgs-6 overexpression has no measurable effect on egg-laying behavior, locomotion, or viability; the rgs-6 expression pattern has not yet been reported.
46	C49A1.10	C49A1.10	n/a	chrI 14,243,227	contains similarity to Mus musculus Proteinase activated receptor 3 precursor (PAR-3) (Thrombin receptor-slike 2) (Coagulation factor II receptor-like 2).; SW:PAR3_MOUSE
47	tsr-1	F53G2.6	n/a	chrII 2,466,865	tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
48	F29B9.11	F29B9.11	n/a	chrIV 4,659,939
49	sul-1	K09C4.8	n/a	chrX 3,269,056	sul-1 encodes a member of the sulfatase family.
50	zyg-8	Y79H2A.11	n/a	chrIII 12,066,888	The zyg-8 gene encodes a protein with a doublecortin-like domain and a protein kinase domain; mutations of zyg-8 impair mitosis at the one-cell embryonic stage, which is normally asymmetrical, but which fails to show proper asymmetry in zyg-8 mutant embryos.