UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T09F5.2	T09F5.2	2.9999999999999996e-85	chrV 15,151,275	contains similarity to Saccharomyces cerevisiae cell wall mannoprotein; SGD:YOR009W
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	T05A6.5	T05A6.5	n/a	chrII 7,824,034	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
4	ceh-30	C33D12.7	n/a	chrX 3,064,554	ceh-30 encodes a homeodomain protein most similar to Drosophila and mammalian BarH1 (OMIM:605211) which function in neuronal cell fate determination; the precise biological role of CEH-30 in C. elegans development and/or behavior is not yet known.
5	C35C5.2	C35C5.2	n/a	chrX 11,539,654	contains similarity to Pfam domains PF04389 (Peptidase family M28) , PF02225 (PA domain) , PF04253 (Transferrin receptor-like dimerisation domain) contains similarity to Interpro domains IPR007365 (Transferrin receptor-like, dimerisation), IPR007484 (Peptidase M28), IPR003137 (Protease-associated PA)
6	C08G5.6	C08G5.6	n/a	chrII 771,341
7	srw-10	ZC482.6	n/a	chrIII 12,755,860	C. elegans SRW-10 protein ;
8	grk-2	W02B3.2	n/a	chrIII 678,078	grk-2 encodes a serine/threonine protein kinase that is most closely related to G protein-coupled receptor (GPCR) kinases; in C. elegans, grk-2 activity is required in chemosensory neurons for normal calcium influx during chemosensation, but is not required for GPCR downregulation; in regulating chemosensation, GRK-2 likely acts upstream of the ODR-3/G alpha protein, as overexpression of ODR-3 can rescue abnormal avoidance behavior in grk-2 mutants; GRK-2 is broadly expressed in the adult nervous system, with expression beginning as early as the 20-30-cell stage of embryonic development and continuing into adulthood.
9	B0410.1	B0410.1	n/a	chrX 2,894,901
10	T07A5.1	T07A5.1	n/a	chrIII 10,304,668	contains similarity to Pfam domain PF06828 Fukutin-related contains similarity to Interpro domain IPR009644 (Fukutin-related)
11	Y116A8C.1	Y116A8C.1	n/a	chrIV 16,901,344	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
12	nhr-126	F44C8.10	n/a	chrV 2,230,032	nhr-126 encodes a member of the nuclear hormone receptor family.
13	F45F2.1	F45F2.1	n/a	chrV 8,538,519	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
14	B0228.9	B0228.9	n/a	chrII 7,762,795
15	xnp-1	B0041.7	n/a	chrI 4,668,742	xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells.
16	srbc-15	F15E11.10	n/a	chrV 2,346,927	C. elegans SRBC-15 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	srw-57	F36G9.1	n/a	chrV 15,954,286	C. elegans SRW-57 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
18	Y54G9A.1	Y54G9A.1	n/a	chrII 13,700,041	contains similarity to Carabus linnei NADH dehydrogenase subunit 5 (Fragment).; TR:O79584
19	rap-2	C25D7.7	n/a	chrV 15,062,961	rap-2 encodes a Ras-related GTPase that is most similar to the RAP2 members of the Ras GTPase superfamily; by homology, RAP-2 is predicted to function as a membrane-localized GTPase that likely plays a role in signal transduction; as animals homozygous for a rap-2 deletion mutation show no obvious abnormalities, the precise role of RAP-2 in C. elegans development and/or behavior is not yet known.
20	ZK1037.1	ZK1037.1	n/a	chrV 15,311,784	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
21	srh-122	R08H2.5	n/a	chrV 15,377,228	C. elegans SRH-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	str-204	F10D2.1	n/a	chrV 7,160,334	C. elegans STR-204 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	srw-113	ZK1037.9	n/a	chrV 15,333,837	C. elegans SRW-113 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
24	M02B1.2	M02B1.2	n/a	chrIV 12,846,951	contains similarity to Melanoplus sanguinipes entomopoxvirus ORF MSV233 hypothetical protein.; TR:Q9YVK8
25	clec-179	C42D4.11	n/a	chrIV 7,183,961	C. elegans CLEC-179 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
26	Y62H9A.14	Y62H9A.14	n/a	chrX 11,922,107	contains similarity to Interpro domain IPR009010 (Aspartate decarboxylase-like fold)
27	F46F5.15	F46F5.15	n/a	chrII 788,813
28	C08E3.13	C08E3.13	n/a	chrII 1,632,158	C08E3.13 encodes a novel protein; expression studies indicate that C08E3.13 expression is positively regulated by signaling through the DBL-1/TGF-beta signaling pathway; in situ hybridization experiments reveal that C08E3.13 transcripts are expressed in the intestine and the vulva.
29	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
30	F42G2.6	F42G2.6	n/a	chrII 2,428,176	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000533 (Tropomyosin), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
31	srab-25	ZK697.7	n/a	chrV 1,740,043	C. elegans SRAB-25 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
32	M01G12.10	M01G12.10	n/a	chrI 12,119,338	contains similarity to Homo sapiens Hypothetical protein KIAA0477; ENSEMBL:ENSP00000316434
33	Y57G7A.6	Y57G7A.6	n/a	chrII 1,283,801	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
34	Y45G12C.11	Y45G12C.11	n/a	chrV 2,551,494	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
35	K06A1.1	K06A1.1	n/a	chrII 6,455,658	K06A1.1 encodes an AP-2-like transcription factor.
36	H35N09.2	H35N09.2	n/a	chrX 8,604,813
37	F46B3.8	F46B3.8	n/a	chrV 20,618,293	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
38	srz-58	F31E9.5	n/a	chrV 17,318,799	C. elegans SRZ-58 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
39	F21G4.4	F21G4.4	n/a	chrX 9,898,328	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
40	F56C4.1	F56C4.1	n/a	chrIV 10,638,106	contains similarity to Brachydanio rerio D121 protein (Fragment).; TR:Q90ZG9
41	F25E2.1	F25E2.1	n/a	chrX 803,494	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
42	C17G1.1	C17G1.1	n/a	chrX 9,919,758	contains similarity to Trypanosoma rangeli Kinetoplastid membrane protein 11.; TR:Q7YZC6
43	cyp-25A5	F42A6.4	n/a	chrIV 3,328,559	C. elegans CYP-25A5 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
44	srab-18	T11A5.3	n/a	chrV 9,870,635	C. elegans SRAB-18 protein; contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
45	C46E10.2	C46E10.2	n/a	chrII 3,723,631
46	C30G4.6	C30G4.6	n/a	chrX 17,077,020	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
47	R04E5.7	R04E5.7	n/a	chrX 8,797,318
48	ceh-17	D1007.1	n/a	chrI 4,569,495	ceh-17 encodes a phox-2-like homeodomain protein that is a member of the Q50 paired-like class of homeobox proteins and the vertebrate orthologue of Phox2a and Phox2b; that affects ALA and SIA axonal development; ceh-17 affects ALA and SIA antero-posterior axonal growth and navigation, and is expressed in five neurons of the ring ganglia (ALA and the 4 SIAs) with strongest expression in embryos and in L1 stage larvae.
49	F58G11.4	F58G11.4	n/a	chrV 13,674,239	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
50	srh-109	T19C9.4	n/a	chrV 17,219,817	C. elegans SRH-109 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)