UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cdk-1	T05G5.3	0	chrIII 9,747,971	cdk-1 encodes a cyclin-dependent kinase, orthologous to and functionally interchangeable with CDC28 from S. cerevisiae; CDK-1 is required for cell-cycle progression through M phase in both meiosis and mitosis.
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	F02H6.2	F02H6.2	n/a	chrIV 14,197,604	contains similarity to Trichomonas vaginalis G3 Putative uncharacterized protein.; TR:A2F8N8
4	rfc-3	C39E9.13	n/a	chrIV 13,096,350	C. elegans RFC-3 protein; contains similarity to Interpro domains IPR008921 (DNA polymerase III clamp loader subunit, C-terminal), IPR003593 (AAA+ ATPase, core)
5	lrr-1	F33G12.4	n/a	chrII 5,035,345	F33G12.4 encodes a leucine rich repeat-containing protein; loss of F33G12.4 activity via large-scale RNAi indicates that F33G12.4 is essential for embryonic and larval development.
6	apn-1	T05H10.2	n/a	chrII 8,048,264	apn-1 encodes a member of the AP (apurinic or apyrimidinic) endonuclease family.
7	C13A2.9	C13A2.9	n/a	chrV 7,263,287	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
8	C02B10.2	C02B10.2	n/a	chrIV 5,090,651	contains similarity to Homo sapiens SNARE-associated protein Snapin; ENSEMBL:ENSP00000357674
9	W06A11.2	W06A11.2	n/a	chrII 4,060,321
10	bath-41	F37A4.9	n/a	chrIII 6,721,274	The F37A4.9 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
11	F46C5.6	F46C5.6	n/a	chrII 8,842,371	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001953 (Na+/H+ exchanger, isoform 2 (NHE2)), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
12	F14H3.3	F14H3.3	n/a	chrV 16,052,681	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000357794
13	nhr-211	T01G6.5	n/a	chrV 488,034	C. elegans NHR-211 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	K03H1.7	K03H1.7	n/a	chrIII 9,947,654	contains similarity to Saccharomyces cerevisiae major low affinity 55 kDa Centromere/microtubule binding protein; SGD:YLR175W
15	srg-69	F09E5.4	n/a	chrII 5,356,499	C. elegans SRG-69 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
16	F28F8.5	F28F8.5	n/a	chrV 15,574,751	contains similarity to Methanosarcina mazei Glutamyl-tRNA(Gln) amidotransferase subunit E (EC 6.3.5.-) (Glu-ADTssubunit E).; SW:GATE_METMA
17	B0416.4	B0416.4	n/a	chrX 9,279,335	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR001841 (Zinc finger, RING-type), IPR000956 (Stathmin), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
18	srh-21	C02E7.2	n/a	chrV 4,927,412	C. elegans SRH-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	R10E4.6	R10E4.6	n/a	chrIII 4,294,138
20	R06C7.2	R06C7.2	n/a	chrI 7,234,078	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86KG8
21	rpt-5	F56H1.4	n/a	chrI 5,742,805	rpt-5 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-5 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
22	pcn-1	W03D2.4	n/a	chrIV 4,048,721	pcn-1 encodes the C. elegans ortholog of proliferating cell nuclear antigen (PCNA), an acidic protein that is an essential component of the DNA replication and repair machinery and serves as a processivity factor for DNA polymerase delta; PCN-1 is required for early embryogenesis and for proper germ-line development, and directly interacts with CKI-2, a cyclin-dependent kinase inhibitor homolog that may be required for cell cycle progression during embryogenesis, and with ATL-1/PI3K, KIN-20, MRT-2/RAD1, and RFC-1, proteins that all play a role in the DNA damage checkpoint pathway; PCN-1 is highly expressed in ovaries and developing embryos.
23	ZK287.7	ZK287.7	n/a	chrV 9,693,782	contains similarity to Homo sapiens Isoform 2 of RNA pseudouridylate synthase domain-containing protein 3; ENSEMBL:ENSP00000380410
24	lsm-7	ZK593.7	n/a	chrIV 10,933,821	C. elegans LSM-7 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core), IPR017132 (U6 snRNA-associated Sm-like protein LSm7)
25	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
26	E02H9.7	E02H9.7	n/a	chrIII 2,445,442	contains similarity to Homo sapiens Uncharacterized protein MUC17 (Fragment); ENSEMBL:ENSP00000368750
27	rnr-2	C03C10.3	n/a	chrIII 4,094,174	rnr-2 encodes the small subunit of ribonucleotide reductase; by homology, RNR-2 is predicted to function in deoxyribonucleotide biosynthesis; in C. elegans rnr-2 is an essential gene whose activity is required for reproduction and embryonic development.
28	aph-1	VF36H2L.1	n/a	chrI 9,232,806	aph-1 encodes an unfamiliar protein predicted to have seven transmembrane domains; APH-1 is a component of the GLP-1/LIN-12 (Notch) pathway, is required maternally for embryonic viability, and also affects morphogenesis, egg laying, germ line proliferation, and translocation of APH-2 to the cell surface; with PEN-2, APH-1 is required for Notch pathway signaling, gamma-secretase cleavage of beta-amyloid precursor protein, and presenilin protein accumulation.
29	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
30	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.
31	nfya-1	T08D10.1	n/a	chrX 11,945,554	C. elegans NFYA-1 protein; contains similarity to Pfam domain PF02045 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B contains similarity to Interpro domain IPR001289 (CCAAT-binding transcription factor, subunit B)
32	F36F12.8	F36F12.8	n/a	chrV 2,091,148	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
33	nhr-103	F44C8.4	n/a	chrV 2,226,236	nhr-103 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
34	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
35	B0563.8	B0563.8	n/a	chrX 9,174,023
36	kbp-5	C34B2.2	n/a	chrI 10,687,701	C. elegans KBP-5 protein ;
37	T25E12.5	T25E12.5	n/a	chrV 16,745,714	contains similarity to Pfam domain PF01501 Glycosyl transferase family 8 contains similarity to Interpro domain IPR002495 (Glycosyl transferase, family 8)
38	R144.3	R144.3	n/a	chrIII 5,022,586	contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
39	K04G2.10	K04G2.10	n/a	chrI 8,059,153	contains similarity to Homo sapiens Meiosis-specific nuclear structural protein 1; ENSEMBL:ENSP00000260453
40	clec-127	W10G11.5	n/a	chrII 3,568,702	C. elegans CLEC-127 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
41	C13A2.5	C13A2.5	n/a	chrV 7,277,113	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
42	sra-14	F35C5.2	n/a	chrII 12,886,826	C. elegans SRA-14 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
43	C27A12.6	C27A12.6	n/a	chrI 6,054,583	contains similarity to Pfam domain PF01485 IBR domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR002867 (Zinc finger, C6HC-type)
44	srj-11	T28A11.12	n/a	chrV 3,242,029	C. elegans SRJ-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	F10D11.2	F10D11.2	n/a	chrI 8,437,292	contains similarity to Bacillus thuringiensis Pesticidial crystal protein cry8Ca (Insecticidal delta-endotoxinsCryVIIIC(a)) (Crystaline entomocidal protoxin) (130 kDa crystalsprotein).; SW:C8CA_BACTP
46	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
47	F36F12.2	F36F12.2	n/a	chrV 2,093,433	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
48	C25A11.1	C25A11.1	n/a	chrX 9,120,170
49	mec-14	F37C12.12	n/a	chrIII 7,191,528	mec-14 encodes a protein with similarity to the beta-subunits of Shaker-type potassium channels, which are members of the aldo-keto reductase superfamily; MEC-14 is required for response to gentle touch by the six touch receptor neurons, and likely functions to regulate activity of the MEC-4 and MEC-10 degenerin channels; mec-14 expression is detected solely in the touch receptor neurons and is dependent on the MEC-3 LIM domain transcription factor; proper MEC-14 localization in the touch receptor neurons is dependent on MEC-12/alpha-tubulin.
50	npp-12	T23H2.1	n/a	chrI 6,450,639	npp-12 encodes Gp210, an evolutionarily conserved membrane protein of the nuclear pore complex (NPC); NPP-12 is required for embryonic viability and normal nuclear membrane structures.