UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T03D8.7	T03D8.7	4e-45	chrV 20,811,735	contains similarity to Homo sapiens Uncharacterized protein ENSP00000381489; ENSEMBL:ENSP00000335483
2	F14H12.2	F14H12.2	n/a	chrX 4,351,596
3	srg-37	K04C1.1	n/a	chrX 14,234,536	C. elegans SRG-37 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
4	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
5	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
6	srw-138	C44C3.3	n/a	chrV 2,962,370	C. elegans SRW-138 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
7	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
8	agr-1	F41G3.12	n/a	chrII 6,767,868	agr-1 encodes a large (1396-residue) putative agrin, orthologous to human AGRIN (OMIM:103320), EGFLAM, and Q9NQ15; AGR-1 is expressed in buccal epithelium and deposited in pharyngeal basal epithelium; AGR-1 is also expressed in IL1 neurons, distal tip cells, and intestine; an AGR-1 fragment can cluster vertebrate dystroglycan in cell culture; agr-1(eg1770) mutations show no obvious phenotype, including levimasole resistance, and do not enhance other mutations perturbing acetylcholine signalling, the dystrophin-glycoprotein-complex, muscle cell differentiation, or the extracellular matrix.
9	nhr-266	F56H1.2	n/a	chrI 5,738,931	C. elegans NHR-266 protein; contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR003125 (Protein of unknown function WSN)
10	clec-263	F26F2.6	n/a	chrV 20,571,518	C. elegans CLEC-263 protein; contains similarity to Pfam domains PF08277 (PAN-like domain) (2), PF00024 (PAN domain) contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
11	F01G10.7	F01G10.7	n/a	chrIV 10,240,539	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1), IPR008262 (Lipase, active site)
12	srt-72	C36C5.9	n/a	chrV 3,148,851	C. elegans SRT-72 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000215 (Protease inhibitor I4, serpin)
13	K02H11.4	K02H11.4	n/a	chrV 1,529,803	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
14	col-123	W08D2.6	n/a	chrIV 9,822,477	col-123 is homologous to the human gene A TYPE IV COLLAGEN (COL6A1; OMIM:303631), which when mutated is sometimes associated with diffuse leiomyomatosis.
15	ins-32	Y8A9A.6	n/a	chrII 3,803,141	ins-32 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-32 is one of 38 insulin-like peptides in C. elegans and the precise role of INS-32 in C. elegans development is not yet clear as loss of INS-32 function does not result in a mutant phenotype.
16	puf-9	W06B11.2	n/a	chrX 5,843,741	The puf-9 gene encodes a predicted RNA binding protein orthologous to Drosophila PUMILIO and human PUMILIO 2 (OMIM:607205); PUF-9 is required for normal locomotion and fluid balance, and is expressed primarily in somatic tissues; PUF-9 contains a glutamine/asparagine-rich domain.
17	T28A11.18	T28A11.18	n/a	chrV 3,267,438	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
18	ift-74	C18H9.8	n/a	chrII 6,681,205	C. elegans IFT-74 protein; contains similarity to Interpro domains IPR010989 (t-SNARE), IPR000694 (Proline-rich region)
19	srbc-6	C36C5.3	n/a	chrV 3,170,772	C. elegans SRBC-6 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
20	srg-67	ZC317.4	n/a	chrV 5,462,245	C. elegans SRG-67 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
21	pes-1	T28H11.4	n/a	chrIV 5,004,039	C. elegans PES-1 protein; contains similarity to Pfam domain PF00250 Fork head domain contains similarity to Interpro domains IPR011991 (Winged helix repressor DNA-binding), IPR001766 (Fork head transcription factor)
22	F14H8.5	F14H8.5	n/a	chrV 15,021,516	contains similarity to Bacillus cereus Hypothetical membrane spanning protein.; TR:Q812W2
23	T25B6.3	T25B6.3	n/a	chrX 9,027,882
24	Y41C4A.13	Y41C4A.13	n/a	chrIII 11,735,378	contains similarity to Homo sapiens Rabconnectin; ENSEMBL:ENSP00000251076
25	T08G3.7	T08G3.7	n/a	chrV 16,464,369	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
26	F22E5.2	F22E5.2	n/a	chrII 2,665,821
27	F37E3.2	F37E3.2	n/a	chrI 6,427,369	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
28	srx-9	R13D7.6	n/a	chrV 7,394,485	C. elegans SRX-9 protein; contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
29	K04A8.5	K04A8.5	n/a	chrV 6,550,991	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1)
30	srh-223	F47C12.3	n/a	chrIV 3,982,749	C. elegans SRH-223 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	srsx-38	T26E4.14	n/a	chrV 15,806,689	C. elegans SRSX-38 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
32	aat-1	F27C8.1	n/a	chrIV 9,600,317	aat-1 encodes an amino acid transporter catalytic subunit; when co-expressed in Xenopus oocytes with the ATG-2 glycoprotein subunit, AAT-1 is able to facilitate amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; in addition, AAT-1 is able to covalently associate with ATG-2 or ATG-1 to form heterodimers in the Xenopus expression system; when co-expressed with ATG-2, AAT-1 localizes to the cell surface of oocytes, but when expressed alone or with ATG-1, AAT-1 localizes intracellularly.
33	C27F2.8	C27F2.8	n/a	chrIII 4,994,766	contains similarity to Interpro domain IPR000694 (Proline-rich region)
34	srh-217	Y113G7B.2	n/a	chrV 20,189,742	C. elegans SRH-217 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	set-30	ZC8.3	n/a	chrX 5,001,358	set-30 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18; neither set-30(gk314) nor set-30(RNAi) have any obvious phenotypes.
36	Y57G11C.21	Y57G11C.21	n/a	chrIV 14,846,701	contains similarity to Interpro domain IPR000358 (Ribonucleotide reductase)
37	twk-25	M04B2.5	n/a	chrIV 11,507,989	C. elegans TWK-25 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
38	F38A1.11	F38A1.11	n/a	chrIV 1,248,205	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
39	C46H3.3	C46H3.3	n/a	chrX 1,228,487	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
40	srx-67	K07C6.10	n/a	chrV 3,917,627	C. elegans SRX-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
41	cyp-33C5	F41B5.3	n/a	chrV 2,246,015	C. elegans CYP-33C5 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
42	F55H12.3	F55H12.3	n/a	chrI 8,884,703	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF07645 (Calcium binding EGF domain) , PF07699 (GCC2 and GCC3) (3), PF07974 (EGF-like domain) (5), PF00057 (Low-density lipoprotein receptor domain class A) , PF02494 (HYR domain) , PF00084 (Sushi domain (SCR repeat)) (2)contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR011641 (GCC2 and GCC3), IPR016187 (C-type lectin fold), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding), IPR008985 (Concanavalin A-like lectin/glucanase)
43	clpp-1	ZK970.2	n/a	chrII 10,301,745	clpp-1 encodes a mitochondrial protein, homologous to bacterial ClpP, required to initiate the stress response to unfolded mitochondrial proteins; as with its bacterial ortholog, CLPP-1 is predicted to be a proteolytic subunit of a Clp-like protease, with an N-terminal region required for mitochondrial localization, and a C-terminal region of ClpP similarity; in response to a mutation stressing mitochondria, clpp-1(RNAi) animals show reduced HSP-60 levels, inhibited nuclear translocation and hsp-60 activation by DVE-1, and aberrant mitochondrial morphology; CLPP-1 is biochemically inhibited by the ClpP inhibitor Z-LY-CMK and the peptide aldehyde MG132, and may also be blocked by them when injected in vivo; CLPP-1 is expressed in the intestine.
44	fbxb-85	R17.1	n/a	chrIII 10,848,088	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
45	Y53C10A.3	Y53C10A.3	n/a	chrI 11,969,389	Y53C10A.3 encodes a paralog of HSF-1 that might regulate ubq-1, since ubq-1 has 5'-flanking sequences resembling heat shock regulatory elements, yet is uninduced by heat shock.
46	C18F10.2	C18F10.2	n/a	chrIII 6,274,532	contains similarity to Schizosaccharomyces pombe Sporulation-specific protein 15.; SW:Q10411
47	F27C8.5	F27C8.5	n/a	chrIV 9,591,134	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
48	F23C8.3	F23C8.3	n/a	chrI 2,440,875
49	F52C9.3	F52C9.3	n/a	chrIII 5,324,039	contains similarity to Pfam domain PF00781 Diacylglycerol kinase catalytic domain (presumed) contains similarity to Interpro domain IPR001206 (Diacylglycerol kinase, catalytic region)
50	che-13	F59C6.7	n/a	chrI 10,511,288	che-13 encodes a novel protein homologous to mammalian IFT57/Hippi (OMIM:606621, protein interactor of Huntingtin-interacting protein 1 that is implicated in neuronal apoptosis in the Huntington disease state); CHE-13 is a proposed component of the intraflagellar transport (IFT) complex B, and is required for the construction and maintenance of cilia on a subset of sensory neurons; in addition, CHE-13 is required for proper localization of OSM-5, a murine polaris homolog, to IFT complex B; CHE-13 is expressed in ciliated sensory neurons including the amphids, phasmids, inner and outer labial neurons, and sensory rays of the male tail, localizing to the cilia base (transition zone) as well as to the axoneme; che-13 expression, like that of ciliogenic genes osm-1, osm-5, osm-6, and che-2, is positively regulated by the DAF-19 RFX-type transcription factor.