UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	amx-1	R13G10.2	0	chrIII 3,824,311	C. elegans AMX-1 protein; contains similarity to Pfam domains PF01593 (Flavin containing amine oxidoreductase) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR001613 (Flavin-containing amine oxidase), IPR000960 (Flavin-containing monooxygenase FMO), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding), IPR007526 (SWIRM)
2	sedl-1	W05H7.3	n/a	chrX 1,439,758	C. elegans SEDL-1 protein; contains similarity to Pfam domain PF04628 Sedlin, N-terminal conserved region contains similarity to Interpro domains IPR011012 (Longin-like), IPR006722 (Sedlin)
3	glit-1	F55D10.3	n/a	chrX 4,713,649	C. elegans GLIT-1 protein; contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
4	ceh-41	T26C11.5	n/a	chrX 1,847,671	ceh-41 encodes a a ONECUT class CUT homeobox protein with a single N-terminal OCAM domain; the OCAM domain is a nematode-specific motif conserved between CEH-21, CEH-41, and T02B5.2; ceh-41 is one of three nematode-specific ONECUT genes in a cluster with ceh-21 and ceh-39; ceh-41 has no obvious function in mass RNAi assays.
5	F47G4.2	F47G4.2	n/a	chrI 14,080,352	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
6	dep-1	F44G4.8	n/a	chrII 9,012,700	dep-1 encodes a class III receptor protein tyrosine phosphatase (R-PTP) orthologous to human R-PTPs such as PTPRJ/Dep-1 (mutated in epithelial cancers; OMIM:600925); DEP-1 is required, redundantly with LIP-1 and LET-60, and downstream of LIN-12, to promote secondary over primary vulval fate in the P5.p and P7.p lineages; DEP-1 is expressed in P5.p and P7.p lineages, and dep-1 acts cell-autonomously in these lineages; DEP-1 colocalizes with LET-23 in punctae, and binds LET-23 in vitro; DEP-1, with LIP-1, is also required for normal duct cell and excretory pore development; dep-1 mutations are wild-type in isolation, but have vulval phenotypes with added mutations in lin-15, lip-1, or let-60; DEP-1 laterally inhibits secondary vulval fates in parallel with LIN-12/Notch signalling; in primary (P5.p) vulval cells, LET-60/RAS-activated SUR-2 inhibits dep-1 and lin-12 expression; since RNAi of 125 out of 165 predicted C. elegans protein phosphatase genes fails to enhance lip-1 mutations, the LIP-1/DEP-1 interaction is likely to be highly specific.
7	T05G5.1	T05G5.1	n/a	chrIII 9,741,123	contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like)
8	T10B5.3	T10B5.3	n/a	chrV 1,866,374	contains similarity to Pfam domain PF08162 NUC189 domain contains similarity to Interpro domain IPR012979 (Protein of unknown function NUC189, C-terminal)
9	ZK418.5	ZK418.5	n/a	chrIII 7,073,217	contains similarity to Mus musculus Transmembrane protein 147.; SW:Q9CQG6
10	pix-1	K11E4.4	n/a	chrX 13,730,745	C. elegans PIX-1 protein ;
11	pro-1	R166.4	n/a	chrII 10,540,649	pro-1 encodes a WD-repeat-containing protein that is orthologous to Saccharomyces cerevisiae IPI3; pro-1 activity is required for ribosome biogenesis and specifically, for efficient processing of intervening sequence 2 (ITS2) from rRNA intermediates during 26S rRNA maturation; during development, pro-1 is essential for larval growth, fertility, and normal cell division patterns; in addition, pro-1 is required cell autonomously in the somatic gonad for proper spatial and temporal regulation of germline development and proliferation; a pro-1 promoter::gfp fusion construct reveals that pro-1 is widely expressed in the embryo as well as in every major post-embryonic lineage including the somatic gonad.
12	tag-289	F14F3.3	n/a	chrX 10,523,120	C. elegans TAG-289 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
13	ZC196.5	ZC196.5	n/a	chrV 8,731,102	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domain IPR007883 (Protein of unknown function DUF713)
14	twk-28	C52B9.6	n/a	chrX 4,276,975	C. elegans TWK-28 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
15	E04D5.2	E04D5.2	n/a	chrII 10,420,700	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
16	F13E6.2	F13E6.2	n/a	chrX 10,671,215	contains similarity to Pfam domain PF05186 Dpy-30 motif contains similarity to Interpro domains IPR000850 (Adenylate kinase), IPR007858 (Dpy-30), IPR011769 (Adenylate/cytidine kinase, N-terminal)
17	cpf-2	F56A8.6	n/a	chrIII 13,267,824	C. elegans CPF-2 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
18	K01A2.3	K01A2.3	n/a	chrII 315,416
19	glt-6	R05G6.6	n/a	chrIV 7,505,011	glt-6 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
20	hint-1	F21C3.3	n/a	chrI 7,280,150	C. elegans HINT-1 protein; contains similarity to Pfam domain PF01230 HIT domain contains similarity to Interpro domains IPR001310 (Histidine triad (HIT) protein), IPR011151 (Histidine triad motif), IPR011146 (Histidine triad-like motif)
21	W04C9.4	W04C9.4	n/a	chrI 462,326
22	F10G8.6	F10G8.6	n/a	chrI 10,047,224	F10G8.6 encodes an homolog of S. cerevisiae CFD1 (also known as YIL003W/DRE3), a putative P-loop ATPase conserved in eukaryotes and required in yeast for 4Fe-4S cluster assembly; F10G8.6 is also homologous to yeast NBP35/YGL091C; in C. elegans, F10G8.6 is required for normally rapid growth and maintenance of the germline; F10G8.6 protein was predicted to be mitochondrial on the basis of its phylogenetic profile.
23	D1025.1	D1025.1	n/a	chrX 14,521,627	contains similarity to Homo sapiens Splice isoform 3 of Q9ULU4 Protein kinase C binding protein 1; ENSEMBL:ENSP00000262975
24	C30C11.1	C30C11.1	n/a	chrIII 8,450,050	contains similarity to Pfam domain PF01783 Ribosomal L32p protein family contains similarity to Interpro domain IPR002677 (Ribosomal protein L32p)
25	F59E11.2	F59E11.2	n/a	chrV 9,002,297	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
26	fbxa-216	Y47H9C.10	n/a	chrI 11,902,379	C. elegans FBXA-216 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
27	F19C6.3	F19C6.3	n/a	chrX 10,007,249	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF00093 (von Willebrand factor type C domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR008037 (Proteinase inhibitor I19, pacifastin), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR001007 (von Willebrand factor, type C)
28	F54D7.2	F54D7.2	n/a	chrI 4,807,641	contains similarity to Pfam domain PF01066 CDP-alcohol phosphatidyltransferase contains similarity to Interpro domains IPR014472 (Choline/ethanolaminephosphotransferase), IPR000462 (CDP-alcohol phosphatidyltransferase)
29	D2005.1	D2005.1	n/a	chrI 7,785,055	contains similarity to Pfam domain PF02137 Adenosine-deaminase (editase) domain contains similarity to Interpro domain IPR002466 (Adenosine deaminase/editase)
30	C25A1.4	C25A1.4	n/a	chrI 10,171,209	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
31	F16G10.9	F16G10.9	n/a	chrII 2,385,448	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
32	T07A9.1	T07A9.1	n/a	chrIV 384,318	contains similarity to Homo sapiens Protein; VG:OTTHUMP00000025811
33	F53B1.6	F53B1.6	n/a	chrX 2,116,438	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR001279 (Beta-lactamase-like)
34	W06A11.4	W06A11.4	n/a	chrII 4,056,790
35	F37F2.2	F37F2.2	n/a	chrI 1,442,805	contains similarity to Pfam domain PF01922 SRP19 protein contains similarity to Interpro domain IPR002778 (Signal recognition particle, SRP19 subunit)
36	B0205.8	B0205.8	n/a	chrI 10,729,585	contains similarity to Homo sapiens hypothetical protein LOC25940; ENSEMBL:ENSP00000238823
37	F10E7.5	F10E7.5	n/a	chrII 7,112,410	contains similarity to Pfam domain PF00466 Ribosomal protein L10 contains similarity to Interpro domain IPR001790 (Ribosomal protein L10)
38	F54F2.7	F54F2.7	n/a	chrIII 8,806,716	contains similarity to Interpro domain IPR011053 (Single hybrid motif)
39	M04F3.4	M04F3.4	n/a	chrI 4,772,433	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
40	dnj-14	K02G10.8	n/a	chrX 4,710,717	This gene encodes a protein containing a DnaJ ('J') domain.
41	rha-1	T07D4.3	n/a	chrII 8,880,999	rha-1 encodes an ATP-dependent DEAD/H box RNA helicase orthologous to human RNA helicase A and Drosophila Maleless, an essential component of the dosage compensation machinery required for increased X-linked transcription in males; by homology, RHA-1 is predicted to function in regulation of transcription, translation, RNA processing, and/or RNA replication; in C. elegans, RHA-1 is required for germ cell proliferation, normal germ cell nuclear morphology, RNA-mediated interference (RNAi) of germline-expressed genes, and silencing of germline-expressed transgenes; RHA-1 is reported to localize to the nucleus and the cytoplasm.
42	R12C12.5	R12C12.5	n/a	chrII 6,044,615	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
43	tra-4	F53B3.1	n/a	chrX 2,855,643	C. elegans TRA-4 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR008162 (Inorganic pyrophosphatase), IPR015880 (Zinc finger, C2H2-like), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
44	F07E5.5	F07E5.5	n/a	chrII 2,056,499	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR013084 (Zinc finger, CCHC retroviral-type), IPR001878 (Zinc finger, CCHC-type)
45	F26D11.1	F26D11.1	n/a	chrV 7,982,245	contains similarity to Pfam domain PF01202 Shikimate kinase contains similarity to Interpro domains IPR000623 (Shikimate kinase), IPR006001 (Carbohydrate kinase, thermoresistant glucokinase)
46	cdh-9	F59C12.1	n/a	chrX 16,598,558	cdh-9 encodes a member of the cadherin superfamily of transmembrane glycoproteins that mediate homophilic cell-cell adhesion; as loss of CDH-9 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CDH-9 in C. elegans development and/or behavior is not yet known.
47	B0310.6	B0310.6	n/a	chrX 530,795
48	C34C12.8	C34C12.8	n/a	chrIII 3,460,983	contains similarity to Pfam domain PF01025 GrpE contains similarity to Interpro domains IPR009012 (GrpE nucleotide exchange factor, head), IPR013805 (GrpE nucleotide exchange factor, coiled-coil), IPR000740 (GrpE nucleotide exchange factor)
49	K07E3.2	K07E3.2	n/a	chrX 8,105,875
50	F23F12.3	F23F12.3	n/a	chrIII 6,504,028	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)