UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	R13D7.2	R13D7.2	0	chrV 7,410,557	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	T02D1.6	T02D1.6	n/a	chrIV 17,410,914	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002232 (5-Hydroxytryptamine 6 receptor), IPR000276 (GPCR, rhodopsin-like)
4	unc-14	K10D3.2	n/a	chrI 7,125,516	The unc-14 gene encodes an activity required for both axonogenesis and sex myoblast migration.
5	clec-89	C09D1.2	n/a	chrI 4,072,314	C. elegans CLEC-89 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
6	glb-3	C06H2.5	n/a	chrV 11,139,410	glb-3 encodes a globin with no obvious function in mass RNAi assays.
7	daf-14	F01G10.8	n/a	chrIV 10,254,701	daf-14 encodes a Smad-related protein that is unusual in that while its C-terminus is well-conserved with Smad proteins, it lacks the N-terminal DNA binding domain found in all other known Smads; DAF-14 is predicted to function as a transducer of the DAF-7/TGF-beta-mediated signal that promotes reproductive growth and negatively regulates dauer formation; as reduction of daf-14 function enhances the dauer constitutive phenotype of daf-8 mutants, and overexpression of daf-14 can rescue daf-8 mutant animals, it is likely that the DAF-14 and DAF-8 Smad proteins function in parallel to control dauer formation; further genetic analyses suggest that DAF-14 and DAF-8 function to antagonize the activities of the DAF-3 Smad and DAF-5 Sno/Ski oncoprotein, which are required for dauer formation; a DAF-14::GFP reporter is expressed in a dynamic pattern in tissues, such as the hypodermis, intestine, and pharynx, that are remodeled during dauer development.
8	mec-18	C52B9.9	n/a	chrX 4,272,688	mec-18 encodes a protein similar to firefly luciferase and plant protein 4-coumarate coA ligase; mec-18 is involved in sensory mechanotransduction; genetic interactions with other mec genes suggest that mec-18 may be involved in negative regulation of the degenerin channel in the touch receptor neurons; mec-18 is expressed exclusively in the touch cells.
9	ZK899.1	ZK899.1	n/a	chrX 9,447,071
10	F38B6.1	F38B6.1	n/a	chrX 6,700,523
11	ztf-2	F13G3.1	n/a	chrI 7,292,255	C. elegans ZTF-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR013993 (Zinc finger, N-recognin, metazoa), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
12	fbxa-115	Y113G7B.3	n/a	chrV 20,186,739	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
13	R02F2.8	R02F2.8	n/a	chrIII 5,494,067	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane)
14	K02E11.4	K02E11.4	n/a	chrV 14,247,777	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
15	bath-46	T07H3.2	n/a	chrII 1,598,755	C. elegans BATH-46 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
16	Y54E2A.1	Y54E2A.1	n/a	chrII 14,736,737	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
17	glr-5	ZC196.7	n/a	chrV 8,718,671	glr-5 encodes a kainate (non-NMDA)-type ionotropic glutamate receptor subunit; GLR-5 activity is required for normal brood sizes, especially at high temperatures; GLR-5 is expressed in neurons.
18	F20D6.8	F20D6.8	n/a	chrV 8,166,494	contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
19	ifc-1	F37B4.2	n/a	chrV 2,882,485	ifc-1 encodes a nonessential intermediate filament protein; IFC-1 is predicted to function as a structural component of the cytoskeleton; IFC-1 has no function in RNAi assays.
20	srr-1	W07G4.6	n/a	chrV 13,051,818	C. elegans SRR-1 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
21	ins-5	ZK84.3	n/a	chrII 5,998,628	ins-5 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-5 is one of 38 insulin-like peptides in C. elegans and is expressed in the amphid sensory neurons, labial neurons, the nerve ring, other neurons, and the vulva; the precise role of INS-5 in C. elegans development is not yet clear as loss of function does not result in a mutant phenotype.
22	K08D8.3	K08D8.3	n/a	chrIV 12,905,268	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
23	C29F9.6	C29F9.6	n/a	chrIII 115,990	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domains IPR003101 (Coactivator CBP, KIX), IPR000197 (Zinc finger, TAZ-type)
24	Y43F8A.5	Y43F8A.5	n/a	chrV 19,387,467	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
25	nas-25	F46C5.3	n/a	chrII 8,827,065	nas-25 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-25::GFP promoter fusion is expressed in the pharynx and pharyngeal-intestinal valve.
26	pho-4	T16D1.2	n/a	chrII 5,237,340	C. elegans PHO-4 protein ;
27	haf-1	C30H6.6	n/a	chrIV 17,377,825	haf-1 encodes a predicted transmembrane protein of the ATP-binding cassette (ABC) transporter superfamily; by homology, HAF-1 is proposed to function in ATP-dependent transport of molecules across plasma and intracellular membranes; however, as loss of HAF-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HAF-1 in C. elegans development and/or behavior is not yet known.
28	F13A2.4	F13A2.4	n/a	chrV 4,399,097
29	ptr-5	C53C11.3	n/a	chrX 17,322,508	ptr-5 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-5 is weakly required for normal molting from L4 to adult stages; PTR-5 is also required for normal growth to full size and locomotion; PTR-5 is expressed in head and tail neurons, and in ventral nerve cord.
30	tag-209	R06F6.11	n/a	chrII 10,787,542	C. elegans TAG-209 protein ;
31	K11E4.1	K11E4.1	n/a	chrX 13,715,160	contains similarity to Pfam domain PF01764 (Lipase (class 3))
32	grsp-2	T28C6.1	n/a	chrIV 8,817,412	C. elegans GRSP-2 protein; contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein), IPR001151 (GPR6 orphan receptor)
33	cyp-33C7	F41B5.2	n/a	chrV 2,251,536	C. elegans CYP-33C7 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
34	AC8.4	AC8.4	n/a	chrX 227,022
35	C28F5.4	C28F5.4	n/a	chrII 7,521,547	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
36	F55C12.4	F55C12.4	n/a	chrII 5,857,731
37	Y7A9A.1	Y7A9A.1	n/a	chrIV 16,199,192	contains similarity to Pfam domain PF01019 Gamma-glutamyltranspeptidase contains similarity to Interpro domain IPR000101 (Gamma-glutamyltranspeptidase)
38	lev-1	F09E8.7	n/a	chrIV 13,176,746	lev-1 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR) which, when mutated, confers resistance to levamisole; LEV-1 is required for completely normal locomotion, and forms a cation channel when coexpressed with UNC-38 or UNC-63 and UNC-29; LEV-1 falls into the 'UNC-29' class of nAChR subunits, which includes UNC-29, ACR-2, and ACR-3.
39	nhr-6	C48D5.1	n/a	chrIII 3,576,162	nhr-6 encodes a nuclear receptor of the NR4A4 subfamily that is orthologous to the mammalian NGFI-B receptors and the Drosophila HR38 nuclear receptor (DHR38) that has been implicated in molting and metamorphosis; by homology, NHR-6 likely functions as a transcription factor that, based upon RNAi experiments, is required for normal ovulation and/or spermathecal development or function; an nhr-6 reporter fusion is expressed primarily in the anterior and posterior spermatheca during L3 and L4 larval stages, with some weak and variable expression also observed in two chemosensory neurons; nhr-6 mRNA is expressed in an oscillating manner throughout larval development, in a pattern that is slightly irregular with respect to the timing of larval molts and that exhibits consistently lower expression at the times when these molts actually occur.
40	clec-51	B0218.6	n/a	chrIV 8,162,862	C. elegans CLEC-51 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR003990 (Pancreatitis-associated protein), IPR001304 (C-type lectin), IPR002352 (Eosinophil major basic protein)
41	lin-33	H32C10.2	n/a	chrIV 5,931,939	C. elegans LIN-33 protein; contains similarity to Interpro domain IPR002873 (Non-structural protein NSP3, Rotavirus)
42	W02B12.1	W02B12.1	n/a	chrII 11,450,148	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
43	srh-174	F40D4.1	n/a	chrV 17,179,348	C. elegans SRH-174 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	F39H12.3	F39H12.3	n/a	chrX 839,898	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) (3), PF02197 (Regulatory subunit of type II PKA R-subunit) contains similarity to Interpro domains IPR003117 (cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta), IPR000048 (IQ calmodulin-binding region)
45	ttr-28	R90.3	n/a	chrV 12,904,670	C. elegans TTR-28 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
46	F38H4.3	F38H4.3	n/a	chrIV 11,845,293	contains similarity to Interpro domain IPR000694 (Proline-rich region)
47	F52E1.2	F52E1.2	n/a	chrV 8,411,177	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
48	ZC190.5	ZC190.5	n/a	chrV 8,672,433
49	Y37D8A.2	Y37D8A.2	n/a	chrIII 12,822,776	contains similarity to Pfam domain PF04916 Phospholipase B contains similarity to Interpro domains IPR007000 (Laminin A), IPR013032 (EGF-like region, conserved site)
50	H04M03.12	H04M03.12	n/a	chrIV 5,900,480