UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	M04G7.1	M04G7.1	2e-158	chrIV 456,400	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000877 (Proteinase inhibitor I12, Bowman-Birk), IPR003582 (Metridin-like ShK toxin)
2	pqn-60	R11G11.7	n/a	chrV 504,306	pqn-60 encodes a 154-residue, glutamine/asparagine (Q/N)-rich ('prion'-like) protein, predicted to have coiled-coil structure, with many paralogs in nematodes but no obvious non-nematode orthologs; PQN-60 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
3	F08G2.5	F08G2.5	n/a	chrII 13,833,272	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
4	flp-13	F33D4.3	n/a	chrIV 7,697,747	C. elegans FLP-13 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
5	scl-3	F49E11.11	n/a	chrIV 13,060,112	C. elegans SCL-3 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
6	dod-6	T20G5.7	n/a	chrIII 10,197,925	C. elegans DOD-6 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
7	C01G10.6	C01G10.6	n/a	chrV 15,087,952	contains similarity to Staphylococcus aureus Staphylococcal secretory antigen ssaA2 precursor.; SW:Q6GED5
8	C15C7.4	C15C7.4	n/a	chrX 3,146,822
9	ttr-28	R90.3	n/a	chrV 12,904,670	C. elegans TTR-28 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
10	B0238.12	B0238.12	n/a	chrV 5,268,306	B0238.12 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; B0238.12 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; B0238.12 has no obvious function in mass RNAi assays.
11	F28A12.3	F28A12.3	n/a	chrV 8,641,003
12	K08D9.4	K08D9.4	n/a	chrV 3,199,601	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative), IPR003089 (Alpha/beta hydrolase)
13	M7.12	M7.12	n/a	chrIV 11,097,281	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
14	C49G7.6	C49G7.6	n/a	chrV 4,041,399
15	ins-30	ZC334.2	n/a	chrI 14,035,617	ins-30 encodes an insulin-like peptide.
16	mec-9	C50H2.3	n/a	chrV 9,911,331	mec-9 encodes a predicted extracellular protein containing six EGF-like repeats,five Kunitz-type protease inhibitor domains, and a glutamic acid-rich region possibly involved in protein-protein interactions; mec-9 encodes two proteins, only one of which, MEC-9L, appears to be required for normal mechanosensory response to gentle touch and proper functioning of the touch receptor neurons; mec-9 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-9L is expressed and secreted by the touch receptor neurons.
17	glr-5	ZC196.7	n/a	chrV 8,718,671	glr-5 encodes a kainate (non-NMDA)-type ionotropic glutamate receptor subunit; GLR-5 activity is required for normal brood sizes, especially at high temperatures; GLR-5 is expressed in neurons.
18	hen-1	C36B7.7	n/a	chrX 7,116,551	hen-1 encodes a secreted protein that contains a low-density lipoprotein (LDL) receptor motif A; HEN-1 activity is required for integration of sensory stimuli and behavioral plasticity; a hen-1::GFP reporter is expressed in pharyngeal muscles, the vulva, and weakly in a subset of neurons; antibodies to HEN-1 protein detect expression exclusively in the AIY and ASE neurons, where HEN-1 appears to localize to cell bodies and in a punctate pattern in nerve ring axons at sites of synapse formation; HEN-1 expression in AIY appears to be under the control of the TTX-3 LIM domain transcription factor.
19	E02C12.11	E02C12.11	n/a	chrV 9,379,644	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
20	C01G10.4	C01G10.4	n/a	chrV 15,089,864	contains similarity to Staphylococcus aureus Staphylococcal secretory antigen ssaA2 precursor.; SW:Q5HDQ9
21	C55A6.6	C55A6.6	n/a	chrV 11,514,222	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
22	Y43F8C.5	Y43F8C.5	n/a	chrV 19,631,978	contains similarity to Dictyostelium discoideum Myb-like protein (Fragment).; SW:MYBH_DICDI
23	C01B4.8	C01B4.8	n/a	chrV 2,491,606	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
24	C49G7.10	C49G7.10	n/a	chrV 4,041,191	contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
25	dct-19	C32H11.13	n/a	chrIV 12,943,591	C. elegans DCT-19 protein; contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
26	cyp-33C8	R08F11.3	n/a	chrV 3,802,105	C. elegans CYP-33C8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
27	sul-2	D1014.1	n/a	chrV 8,158,775	sul-2 is orthologous to the human gene ARYLSULFATASE A (ARSA; OMIM:250100), which when mutated leads to metachromatic leukodystrophy.
28	tbb-6	T04H1.9	n/a	chrV 12,262,563	C. elegans TBB-6 protein; contains similarity to Pfam domains PF00091 (Tubulin/FtsZ family, GTPase domain) , PF03953 (Tubulin/FtsZ family, C-terminal domain) contains similarity to Interpro domains IPR002454 (Gamma tubulin), IPR002452 (Alpha tubulin), IPR002453 (Beta tubulin), IPR000217 (Tubulin), IPR003008 (Tubulin/FtsZ, GTPase), IPR004057 (Epsilon tubulin), IPR002967 (Delta tubulin), IPR008280 (Tubulin/FtsZ, C-terminal)
29	gst-40	F56B3.10	n/a	chrIV 761,476	C. elegans GST-40 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
30	nhr-120	C25B8.6	n/a	chrX 6,638,552	C. elegans NHR-120 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	sol-1	C15A11.3	n/a	chrI 7,392,485	C. elegans SOL-1 protein; contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
32	F35H10.3	F35H10.3	n/a	chrIV 8,326,450
33	H04M03.12	H04M03.12	n/a	chrIV 5,900,480
34	R13A5.9	R13A5.9	n/a	chrIII 7,577,267	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR001958 (Tetracycline resistance protein, TetA), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
35	K09D9.1	K09D9.1	n/a	chrV 4,025,632
36	cal-4	T07G12.1	n/a	chrIV 10,528,321	cal-4 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-1, CAL-2, CAL-3 and CMD-1); as loss of cal-4 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-4 in C. elegans development and/or behavior is not yet known.
37	F53A9.9	F53A9.9	n/a	chrX 8,720,477	contains similarity to Bacillus subtilis Uncharacterized protein yeeK.; SW:O31510
38	C01G10.5	C01G10.5	n/a	chrV 15,089,276	contains similarity to Homo sapiens Glycine/tyrosine-rich protein; ENSEMBL:ENSP00000335001
39	glb-3	C06H2.5	n/a	chrV 11,139,410	glb-3 encodes a globin with no obvious function in mass RNAi assays.
40	nhr-7	F54D1.4	n/a	chrIV 11,267,544	C. elegans NHR-7 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000694 (Proline-rich region), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	T02D1.6	T02D1.6	n/a	chrIV 17,410,914	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002232 (5-Hydroxytryptamine 6 receptor), IPR000276 (GPCR, rhodopsin-like)
42	T27A10.2	T27A10.2	n/a	chrX 3,586,399
43	daf-5	W01G7.1	n/a	chrII 14,035,373	daf-5 encodes a proline-rich protein, conserved in C. briggsae but not observed in non-nematode genomes, that promotes dauer formation in the group II branch of the dauer pathway, may regulate chemosensation via AWC neurons, and may regulate egg laying; daf-5 mutations suppress the dauer phenotype of group II Daf-c mutants; daf-5(e1385) partially suppresses dauer formation by aex-6(sa699) mutants at 26.8 degrees C.
44	nhr-6	C48D5.1	n/a	chrIII 3,576,162	nhr-6 encodes a nuclear receptor of the NR4A4 subfamily that is orthologous to the mammalian NGFI-B receptors and the Drosophila HR38 nuclear receptor (DHR38) that has been implicated in molting and metamorphosis; by homology, NHR-6 likely functions as a transcription factor that, based upon RNAi experiments, is required for normal ovulation and/or spermathecal development or function; an nhr-6 reporter fusion is expressed primarily in the anterior and posterior spermatheca during L3 and L4 larval stages, with some weak and variable expression also observed in two chemosensory neurons; nhr-6 mRNA is expressed in an oscillating manner throughout larval development, in a pattern that is slightly irregular with respect to the timing of larval molts and that exhibits consistently lower expression at the times when these molts actually occur.
45	F13A2.4	F13A2.4	n/a	chrV 4,399,097
46	F35H12.1	F35H12.1	n/a	chrX 936,580	contains similarity to Interpro domain IPR015649 (Schwannomin interacting protein 1)
47	F38B2.2	F38B2.2	n/a	chrX 11,278,957	contains similarity to Pneumocystis carinii DNA-directed RNA polymerase III (EC 2.7.7.6) (Fragment).; TR:Q06358
48	T16G1.7	T16G1.7	n/a	chrV 12,933,975	T16G1.7 is orthologous to the human gene ALIAS DLC1~CANDIDATE TUMOR SUPPRESSOR GENE (DLEC1; OMIM:604050), which when mutated leads to disease.
49	T02E9.1	T02E9.1	n/a	chrV 11,351,210	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
50	F46F5.4	F46F5.4	n/a	chrII 805,580	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)