UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-268	K06B4.6	0	chrV 15,690,903	C. elegans NHR-268 protein
2	F22D6.8	F22D6.8	n/a	chrI 7,099,204
3	F56C3.7	F56C3.7	n/a	chrX 1,370,660
4	clec-195	Y116A8C.21	n/a	chrIV 17,044,558	C. elegans CLEC-195 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
5	C17E7.10	C17E7.10	n/a	chrV 3,899,486	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
6	F47B7.5	F47B7.5	n/a	chrX 3,768,291	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
7	F44G3.10	F44G3.10	n/a	chrV 16,139,209	F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
8	F18H3.1	F18H3.1	n/a	chrX 13,520,521	contains similarity to Pfam domain PF00622 SPRY domain contains similarity to Interpro domains IPR001870 (B302, (SPRY)-like), IPR003877 (SPla/RYanodine receptor SPRY)
9	nhr-150	C06B8.1	0.000008	chrV 15,480,433	C. elegans NHR-150 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
10	B0432.1	B0432.1	n/a	chrII 298,462
11	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
12	C06B3.7	C06B3.7	n/a	chrV 13,910,615	contains similarity to Streptococcus agalactiae Tn5252, relaxase.; TR:Q8DZ67
13	ZK218.4	ZK218.4	n/a	chrV 17,100,011	contains similarity to Interpro domain IPR000434 (Polycystic kidney disease type 1 protein)
14	srz-23	F58E2.9	n/a	chrIV 3,454,195	C. elegans SRZ-23 protein ;
15	F20E11.5	F20E11.5	n/a	chrV 17,461,590	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domain IPR005098 (Protein of unknown function DUF281)
16	F16G10.14	F16G10.14	n/a	chrII 2,398,093	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
17	R12B2.2	R12B2.2	n/a	chrIII 5,808,424	contains similarity to Homo sapiens Isoform 1 of Golgin-45; ENSEMBL:ENSP00000327541
18	srj-22	F28H7.1	n/a	chrV 10,743,082	C. elegans SRJ-22 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	str-141	F47G9.2	n/a	chrV 11,323,048	C. elegans STR-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	hot-7	Y48B6A.9	n/a	chrII 14,212,173	hot-7 encodes a predicted membrane-associated protein that is a member of the Ly-6 superfamily of glycosylphosphatidylinositol (GPI)-linked signaling proteins and is homologous to ODR-2, a neuronally expressed protein required for olfaction; as loss of hot-7 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HOT-7 in C. elegans development and/or behavior is not yet known.
21	F37H8.2	F37H8.2	n/a	chrII 11,173,534	contains similarity to Saccharomyces cerevisiae Structural maintenance of chromosomes (SMC) protein; SGD:YOL034W
22	clec-34	T25E12.8	n/a	chrV 16,736,555	C. elegans CLEC-34 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	Y49E10.25	Y49E10.25	n/a	chrIII 12,490,261	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
24	old-1	C08H9.5	n/a	chrII 9,867,626	old-1 encodes a receptor protein tyrosine kinase; old-1 activity is required for stress resistance and regulation of adult lifespan: old-1 mRNA expression is upregulated in response to stress and in daf-2 and age-1 mutant backgrounds; likewise, overexpression of old-1 in wild-type animals extends lifespan and increases resistance to heat and UV irradiation; an OLD-1::GFP fusion protein is expressed in the anterior region of worms, in neuronal, hypodermal, and pharyngeal tissues, as well as in the proximal region of the male gonad; expression is visible in young adults and appears to increase as animals age and in response to heat, starvation, or UV irradiation.
25	F59B2.11	F59B2.11	n/a	chrIII 9,014,893	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000025312
26	F16G10.8	F16G10.8	n/a	chrII 2,382,692	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
27	Y7A5A.7	Y7A5A.7	n/a	chrX 15,802,663	contains similarity to Murine herpesvirus 72 Membrane virion glycoprotein 150.; TR:Q9DYE3
28	nhr-190	F48G7.11	0.0000007	chrV 641,845	C. elegans NHR-190 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
29	srj-33	T07C12.1	n/a	chrV 9,936,513	C. elegans SRJ-33 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	srh-295	ZK1037.8	n/a	chrV 15,331,670	C. elegans SRH-295 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	C50H11.17	C50H11.17	n/a	chrV 3,097,908	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
32	srh-60	W10G11.9	n/a	chrII 3,585,242	C. elegans SRH-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	srx-46	E02C12.2	n/a	chrV 9,353,867	C. elegans SRX-46 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
34	Y102E9.3	Y102E9.3	n/a	chrIII 6,734,194
35	T24A6.16	T24A6.16	n/a	chrV 3,562,186	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
36	clec-177	E03H12.2	n/a	chrIV 4,987,125	C. elegans CLEC-177 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
37	F10A3.11	F10A3.11	n/a	chrV 16,163,213	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
38	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
39	gst-30	ZK546.11	n/a	chrII 4,934,462	C. elegans GST-30 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
40	C27F2.1	C27F2.1	n/a	chrIII 4,989,295	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
41	C17H1.3	C17H1.3	n/a	chrI 13,105,263	contains similarity to Trichomonas vaginalis G3 Smooth muscle caldesmon, putative.; TR:A2FBI1
42	gcy-27	C06A12.4	n/a	chrIV 17,436,419	C. elegans GCY-27 protein; contains similarity to Pfam domains PF00211 (Adenylate and Guanylate cyclase catalytic domain) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001054 (Adenylyl cyclase class-3/4/guanylyl cyclase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
43	R52.4	R52.4	n/a	chrII 2,107,797
44	Y48E1B.7	Y48E1B.7	n/a	chrII 13,580,236	Y48E1B.7 encodes a C2H2-type zinc-finger protein required for embryonic development and fertility; Y48E1B.7 transcript levels are diminished by ERI-1, RDE-3, and RRF-2, perhaps through endogenous RNAi; Y48E1B.7 is paralogous to MCD-1, but has no obvious non-nematode orthologs; Y48E1B.7 contains a single central zinc-finger and a C-terminal low-complexity region, but no other recognizable protein domains.
45	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
46	T20B12.5	T20B12.5	n/a	chrIII 7,366,839
47	D2013.3	D2013.3	n/a	chrII 9,318,488	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
48	C24A8.5	C24A8.5	n/a	chrX 4,328,634
49	F52B11.5	F52B11.5	n/a	chrIV 14,102,592	contains similarity to Clostridium perfringens Hypothetical protein CPE2159.; TR:Q8XIG1
50	srsx-17	F58D7.1	n/a	chrV 5,929,015	C. elegans SRSX-17 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)