UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	eak-4	F53B2.3	4.9999999999999994e-136	chrIV 12,524,964	eak-4 encodes a novel protein that contains an N-myristoylation signal; eak-4 acts in parallel to akt-1 to regulate insulin-like signaling and dauer formation; EAK-4 is expressed primarily in the neuroendocrine XXXL/R cells, where it associates with the plasma membrane.
2	C31H5.5	C31H5.5	n/a	chrI 9,048,863	contains similarity to Mus musculus Eukaryotic translation initiation factor 2 subunit 2 (Eukaryoticstranslation initiation factor 2 beta subunit) (eIF-2-beta).; SW:IF2B_MOUSE
3	gst-2	K08F4.6	n/a	chrIV 10,140,892	C. elegans GST-2 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
4	F11A5.3	F11A5.3	n/a	chrV 16,195,214	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
5	C30B5.7	C30B5.7	n/a	chrII 6,225,999	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003944 (Protease-activated receptor 4)
6	ceh-7	C34C6.8	n/a	chrII 8,703,530	ceh-7 encodes a homeodomain transcription factor; expressed in cells around the rectum of the male tail.
7	M03A1.3	M03A1.3	n/a	chrII 4,558,668	M03A1.3 encodes a protein with ~10 predicted transmembrane sequences; it has an internal repeat (in residues 74-351 and 377-668), with some similarity in these repeated domains to worm C05D12.1 and C13B4.1, and to mammalian stromal cell derived factor receptor 2.
8	T05E11.8	T05E11.8	n/a	chrIV 11,105,287	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
9	F40G9.6	F40G9.6	n/a	chrIII 179,840
10	aqp-5	C35A5.1	n/a	chrV 10,492,631	aqp-5 encodes a putative aquaporin with no known substrate, since AQP-5 expressed in Xenopus oocytes has no effect on water, glycerol, or urea permeability; AQP-5 also has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-6; AQP-5 is expressed in I1 and I2 pharyngeal interneurons, and is orthologous to human AQP8 (OMIM:603750).
11	nlp-10	F37A8.4	n/a	chrIII 3,934,743	nlp-10 encodes four predicted neuropeptide-like proteins; nlp-10 is part of a GGxY neuropeptide family that has members in several other nematode species; nlp-10 is expressed in a variety of neurons, including ASK, ADL, CAN, two lateral neurons, two anterior pharyngeal neurons, one tail neuron, and one male tail neuron; as loss of nlp-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-10-encoded peptides in development and/or behavior is not yet known.
12	W05B10.4	W05B10.4	n/a	chrV 12,668,893	contains similarity to Pfam domain PF00788 Ras association (RalGDS/AF-6) domain contains similarity to Interpro domain IPR000159 (Ras-association)
13	C02B8.7	C02B8.7	n/a	chrX 8,137,743
14	eat-4	ZK512.6	n/a	chrIII 9,139,280	eat-4 encodes an ortholog of the mammalian BNPI vesicular glutamate transporter that affects chemotaxis, feeding, foraging and thermotaxis; eat-4 is expressed in specific neurons, including M3L and M3R which are known to be glutamatergic.
15	nhr-42	C33G8.6	n/a	chrV 6,999,694	C. elegans NHR-42 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
16	C39B10.3	C39B10.3	n/a	chrX 10,443,924	contains similarity to Saccharomyces cerevisiae Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins; SGD:YDR363W
17	C18A11.2	C18A11.2	n/a	chrX 8,067,797
18	C06G4.5	C06G4.5	n/a	chrIII 7,993,542	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR009150 (Neuropeptide W receptor), IPR000276 (GPCR, rhodopsin-like)
19	C37C3.10	C37C3.10	n/a	chrV 7,862,685
20	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
21	nhr-90	ZK488.2	n/a	chrV 611,490	C. elegans NHR-90 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
22	srt-58	C29G2.5	n/a	chrV 2,575,489	C. elegans SRT-58 protein; contains similarity to Pfam domains PF01748 (Caenorhabditis serpentine receptor-like protein) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type)
23	K10G6.4	K10G6.4	n/a	chrII 3,973,888	contains similarity to Interpro domain IPR000533 (Tropomyosin)
24	B0563.7	B0563.7	n/a	chrX 9,153,274	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
25	srz-79	C09G12.2	n/a	chrIV 3,494,391	C. elegans SRZ-79 protein ;
26	clec-201	C30H6.3	n/a	chrIV 17,359,724	C. elegans CLEC-201 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
27	ast-1	T08H4.3	n/a	chrII 4,131,358	ast-1 encodes a novel ETS-box transcription factor; AST-1 is required for the proper navigation of some interneuron axons to their targets, for differentiation of the ventral cord pioneer neuron AVG, and for pharyngeal morphogenesis; AST-1 is transiently expressed in many head neurons late in their differentiation and axon outgrowth, and in a few pharyngeal cells; AST-1 is at first nuclear, but then relocates to spots in cell bodies and even neuronal processes; hypomorphic ast-1 mutants have axons extending laterally, and crossing over from the right axon tract to the left axon bundle; null ast-1(hd92) mutants are inviable, failing to attach a working pharynx to their cuticle during development and then starving as L1 larvae; behaviorally, hypomorphic ast-1 animals are at least superficially normal, indicating that the ventral nerve cord can tolerate at least some miswiring; AST-1 regulates odr-2 expression, while ast-1 expression is itself regulated by lin-11.
28	ZK757.1	ZK757.1	n/a	chrIII 9,869,795	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR000883 (Cytochrome c oxidase, subunit I), IPR010601 (Protein of unknown function DUF1182)
29	str-45	T09F5.3	n/a	chrV 15,159,744	C. elegans STR-45 protein ; contains similarity to Homo sapiens 42 kDa protein; VG:OTTHUMP00000169906
30	Y43F8B.6	Y43F8B.6	n/a	chrV 19,493,363	contains similarity to Yersinia pestis Putative insecticial toxin.; TR:Q8ZAV3
31	W04G5.7	W04G5.7	n/a	chrI 11,653,511	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
32	T01C8.4	T01C8.4	n/a	chrX 16,788,345	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR004838 (Aminotransferases, class-I, pyridoxal-phosphate-binding site), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
33	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	sru-36	R07B5.6	n/a	chrV 9,842,407	C. elegans SRU-36 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
35	R09D1.5	R09D1.5	n/a	chrII 9,448,892	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
36	C45E5.4	C45E5.4	n/a	chrIV 5,736,046
37	K11D12.9	K11D12.9	n/a	chrV 5,044,302	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
38	srw-91	K04F1.4	n/a	chrV 1,680,088	C. elegans SRW-91 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
39	sri-13	M01G12.13	n/a	chrI 12,141,648	C. elegans SRI-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	ttr-54	T14G10.4	n/a	chrIV 10,156,441	C. elegans TTR-54 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
41	srd-33	T19H12.4	n/a	chrV 4,873,237	C. elegans SRD-33 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
42	ZK816.1	ZK816.1	n/a	chrX 3,359,733
43	srh-39	C06A8.7	n/a	chrII 7,764,656	C. elegans SRH-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	srh-251	R08H2.4	n/a	chrV 15,379,118	C. elegans SRH-251 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	C32D5.1	C32D5.1	n/a	chrII 6,344,783
46	cpx-2	K03A11.2	n/a	chrX 13,067,761	C. elegans CPX-2 protein; contains similarity to Pfam domain PF05835 Synaphin protein contains similarity to Interpro domain IPR008849 (Synaphin)
47	C13A2.7	C13A2.7	n/a	chrV 7,266,655
48	twk-23	F19D8.1	n/a	chrX 13,819,543	twk-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-23 in C. elegans development and/or behavior is not yet known, however TWK-23 may function redundantly with other TWK channels; TWK-23 is expressed in neurons, muscle, the posterior intestine, and diffusely in many other tissues.
49	srt-11	W01D2.4	n/a	chrII 14,806,938	C. elegans SRT-11 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	gly-18	F22D6.11	n/a	chrI 7,111,262	GLY-18 is similar to 2/I N-acetylglucosaminyltransferase.