UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F53A9.3	F53A9.3	3.9999999999999996e-87	chrX 8,708,808
2	R06C7.6	R06C7.6	n/a	chrI 7,246,472	contains similarity to Mus musculus Uncharacterized protein C8orf32 homolog.; SW:Q80WB5
3	ZC204.14	ZC204.14	n/a	chrII 1,662,200
4	F23A7.4	F23A7.4	n/a	chrX 16,212,627	contains similarity to Mus musculus MKIAA0554 protein (Fragment).; TR:Q80TY0
5	sdz-13	F13E9.6	n/a	chrIV 10,878,328	C. elegans SDZ-13 protein ;
6	str-160	ZK697.10	n/a	chrV 1,735,727	C. elegans STR-160 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	mdt-29	K08E3.8	n/a	chrIII 13,776,056	mdt-29 encodes a putative mediator subunit with a prion-like (asparagine- or glutamine-rich) domain; note that K08E3.8 is allegedly an ortholog of Drosophila INTERSEX/IX, but the actual C. elegans IX ortholog appears to be PQN-15); in yeast two-hybrid screens, MDT-29 interacts with SEL-7 and SEL-8; MDT-29 protein also self-associates; RNAi of K08E3.8 weakly enhances the two-anchor-cell phenotype of lin-12(ar170), roughly as much as sel-7 RNAi; since SEL-7 is a novel nuclear protein, MDT-29/SEL-7/SEL-8 is likely to form a nuclear complex formed in response to LIN-12 activation.
8	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
9	ubxn-4	ZK353.8	n/a	chrIII 8,404,541	C. elegans UBXN-4 protein; contains similarity to Pfam domain PF00789 UBX domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR001012 (UBX)
10	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
11	gcy-20	F21H7.9	n/a	chrV 16,251,158	gcy-20 encodes a predicted guanylate cyclase.
12	kle-2	C29E4.2	n/a	chrIII 7,943,584	C. elegans KLE-2 protein ; contains similarity to Homo sapiens Isoform 4 of Condensin-2 complex subunit H2; ENSEMBL:ENSP00000355052
13	F17E5.2	F17E5.2	n/a	chrX 12,396,800	contains similarity to Pfam domains PF00153 (Mitochondrial carrier protein) (3), PF00036 (EF hand) (3)contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003842 (Vacuolating cytotoxin), IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR002167 (Graves disease carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
14	T10C6.5	T10C6.5	n/a	chrV 16,023,741	contains similarity to Pfam domain PF04889 Cwf15/Cwc15 cell cycle control protein contains similarity to Interpro domain IPR006973 (Cwf15/Cwc15 cell cycle control protein)
15	F54D10.8	F54D10.8	n/a	chrII 3,826,789	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
16	gpn-1	F59D12.4	n/a	chrX 15,684,484	gpn-1 encodes a glypican, a heparan sulfate proteoglycan anchored to the cell membrane by a GPI linkage, that is orthologous to Drosophila Dally-like (Dlp) and mammalian glypicans (OMIM:312870, mutated in Simpson-Golabi-Behmel overgrowth syndrome); by homology, GPN-1 is predicted to function as a cell surface protein that regulates intercellular signaling, perhaps within the context of cell division and growth regulation; however, as loss of gpn-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GPN-1 in C. elegans development and/or behavior is not yet known.
17	C49D10.10	C49D10.10	n/a	chrII 3,875,377	C49D10.10 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C49D10.10 has no clear orthologs in other organisms.
18	fbxb-100	Y63D3A.2	n/a	chrI 14,093,529	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
19	Y53C12B.6	Y53C12B.6	n/a	chrII 9,723,099	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
20	ddl-1	F59E12.10	n/a	chrII 5,647,512	ddl-1 encodes a coiled-coil protein orthologous to vertebrate CCD53; loss of ddl-1 activity via RNAi results in a daf-16-dependent increase in lifespan.
21	C27F2.7	C27F2.7	n/a	chrIII 4,982,522	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
22	F53C3.11	F53C3.11	n/a	chrII 3,905,880	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
23	C40A11.3	C40A11.3	n/a	chrII 2,142,086	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
24	C41H7.4	C41H7.4	n/a	chrII 3,004,748	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
25	F53G2.8	F53G2.8	n/a	chrII 2,483,639
26	D1086.2	D1086.2	n/a	chrV 14,097,873	contains similarity to Pfam domain PF01358 (Poly A polymerase regulatory subunit)
27	Y54E5A.7	Y54E5A.7	n/a	chrI 14,713,042	contains similarity to Pfam domain PF00622 SPRY domain contains similarity to Interpro domains IPR001870 (B302, (SPRY)-like), IPR006594 (LisH dimerisation motif), IPR006595 (CTLH, C-terminal to LisH motif), IPR003877 (SPla/RYanodine receptor SPRY)
28	T14B4.2	T14B4.2	n/a	chrII 6,736,402	contains similarity to Pfam domain PF01084 Ribosomal protein S18 contains similarity to Interpro domain IPR001648 (Ribosomal protein S18)
29	T07F12.1	T07F12.1	n/a	chrX 4,895,096	T07F12.1 encodes a member of the histidine phosphatase superfamily orthologous to Bombyx mori ecdysteroid phosphate phosphatase (EPP), human STS1 (OMIM:609201) and human UBASH3A (OMIM:605736); in cell culture, recombinant T07F12.1 is a cytosolic enzyme with steroid phosphatase activity on ecdysone 22-phosphate (E22P), 3-epiecdysone 22-phosphate, 3-epiecdysone 2-phosphate substrates, and prednisolone 21-phosphate substrates, with E22P being preferred; T07F12.1 has no activity against 3-epiecdysone 3(alpha)-phosphate or 1-dehydrotestosterone sodium sulphate; unlike its Bombyx or mammalian orthologs, T07F12.1 lacks non-catalytic SH3 and UBA domains; T07F12.1 is paralogous to C. elegans C52E4.7, F09C12.8, F53B6.7, and F55A11.11.
30	srt-15	C50H11.10	n/a	chrV 3,060,908	C. elegans SRT-15 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
31	C08B6.7	C08B6.7	n/a	chrV 10,132,247	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
32	ZC190.6	ZC190.6	n/a	chrV 8,675,924
33	rnp-2	K08D10.4	n/a	chrIV 4,173,038	rnp-2 encodes the small nuclear ribonucleoprotein (snRNP)-associated protein RNP-2/U1A, which associates with U1 snRNPs; rnp-2 is coexpressed with rnp-3, dnj-15, and K08D10.12 in an operon; RNP-2 and RNP-3 are paralogs with ~50% identity that are more closely related to one another than to non-nematode orthologs; despite their association with distinct snRNPs, RNP-2 and RNP-3 are functionally interchangeable in vivo; either rnp-2(RNAi) or rnp-3(ok1424) animals are viable, with only rpn-2(RNAi) rpn-3(ok1424) animals showing lethality; moreover, RNAi against only RNP-3 causes RNP-2 to associate with RNP-3's normal U2 snRNP partners.
34	C24D10.4	C24D10.4	n/a	chrIV 5,160,919
35	tag-50	M176.1	n/a	chrII 9,413,277	tag-50 encodes a predicted member of the arrestin family.
36	H04M03.1	H04M03.1	n/a	chrIV 5,897,858	contains similarity to Pfam domain PF00821 Phosphoenolpyruvate carboxykinase contains similarity to Interpro domains IPR013035 (Phosphoenolpyruvate carboxykinase, C-terminal), IPR008210 (Phosphoenolpyruvate carboxykinase, N-terminal), IPR008209 (Phosphoenolpyruvate carboxykinase, GTP-utilising)
37	F12F6.8	F12F6.8	n/a	chrIV 11,556,346	contains similarity to Schizosaccharomyces pombe Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylylscyclase).; SW:CYAA_SCHPO
38	Y18D10A.1	Y18D10A.1	n/a	chrI 12,797,263	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding)
39	pax-1	K07C11.1	n/a	chrV 8,225,481	C. elegans PAX-1 protein; contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
40	tsp-3	Y39E4B.4	n/a	chrIII 13,213,403	C. elegans TSP-3 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domain IPR000301 (CD9/CD37/CD63 antigen)
41	F20D1.2	F20D1.2	n/a	chrX 14,972,677	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR001763 (Rhodanese-like), IPR000195 (RabGAP/TBC)
42	mtx-1	F39B2.11	n/a	chrI 14,755,776	C. elegans MTX-1 protein; contains similarity to Interpro domains IPR017410 (Metaxin), IPR010987 (Glutathione S-transferase, C-terminal-like)
43	zyg-9	F22B5.7	n/a	chrII 8,461,098	zyg-9 encodes a predicted microtubule-association protein (MAP) of the XMAP215 family; during early embryonic development, maternal zyg-9 activity is required for microtubule-dependent processes such as meiotic and mitotic spindle organization and pronuclear migration; further, zyg-9 is essential for formation of long astral microtubules; ZYG-9 is required for centrosomal localization of TAC-1, the sole C. elegans TACC family member, with which it interacts, and mutually stabilizes, in vivo; in early embryos, ZYG-9 localizes to the meiotic spindle and spindle poles, as well as to mitotic centrosomes; during metaphase and anaphase ZYG-9 localizes to the central spindle region, and during interphase ZYG-9 is cytoplasmic; proper localization of ZYG-9 to the meiotic spindle is dependent upon wild-type activity of MEI-1, an ATPase essential for meiotic spindle formation, while proper localization of ZYG-9 to centrosomes is dependent, at least in part, upon TAC-1.
44	T03G6.3	T03G6.3	n/a	chrX 2,613,474	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
45	Y39E4B.10	Y39E4B.10	n/a	chrIII 13,147,942	contains similarity to Buchnera aphidicola Hypothetical protein BUsg080.; SW:Y080_BUCAP
46	fbxa-144	F44G3.8	n/a	chrV 16,132,206	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
47	clec-93	ZK39.4	n/a	chrI 11,143,094	C. elegans CLEC-93 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
48	F31D4.2	F31D4.2	n/a	chrV 20,838,947	contains similarity to Pfam domain PF01937 Protein of unknown function DUF89 contains similarity to Interpro domains IPR000408 (Regulator of chromosome condensation, RCC1), IPR002791 (Protein of unknown function DUF89)
49	srt-64	C03A7.9	n/a	chrV 5,168,964	C. elegans SRT-64 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	fbxb-49	K05F6.1	n/a	chrII 1,570,989	C. elegans FBXB-49 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)