UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	taf-11.1	F48D6.1	2e-131	chrX 4,255,964	C. elegans TAF-11.1 protein; contains similarity to Pfam domain PF04719 hTAFII28-like protein conserved region contains similarity to Interpro domains IPR006809 (TAFII28-like protein), IPR000104 (Antifreeze protein, type I), IPR009072 (Histone-fold)
2	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	F33E2.5	F33E2.5	n/a	chrI 12,591,727	contains similarity to Pyrococcus horikoshii Hypothetical protein PH1222.; TR:O58961
6	C07E3.6	C07E3.6	n/a	chrII 10,368,675	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
7	dgn-1	T21B6.1	n/a	chrX 10,922,297	C. elegans DGN-1 protein; contains similarity to Interpro domains IPR015919 (Cadherin-like), IPR013783 (Immunoglobulin-like fold), IPR006644 (Dystroglycan-type cadherin-like), IPR003992 (Pertactin virulence factor, N-terminal)
8	rnp-2	K08D10.4	n/a	chrIV 4,173,038	rnp-2 encodes the small nuclear ribonucleoprotein (snRNP)-associated protein RNP-2/U1A, which associates with U1 snRNPs; rnp-2 is coexpressed with rnp-3, dnj-15, and K08D10.12 in an operon; RNP-2 and RNP-3 are paralogs with ~50% identity that are more closely related to one another than to non-nematode orthologs; despite their association with distinct snRNPs, RNP-2 and RNP-3 are functionally interchangeable in vivo; either rnp-2(RNAi) or rnp-3(ok1424) animals are viable, with only rpn-2(RNAi) rpn-3(ok1424) animals showing lethality; moreover, RNAi against only RNP-3 causes RNP-2 to associate with RNP-3's normal U2 snRNP partners.
9	C15C7.6	C15C7.6	n/a	chrX 3,169,031	contains similarity to Interpro domain IPR003945 (NADH-plastoquinone oxidoreductase, chain 5)
10	psa-4	F01G4.1	n/a	chrIV 11,128,568	The psa-4 (phasmid socket absent) gene encodes an ortholog of SWI2/SNF2, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-4 is probably required during mitosis of the T cells for asymmetric cell division.
11	fzr-1	ZK1307.6	n/a	chrII 9,642,652	fzr-1 encodes a WD repeat-containing protein homologous to Cdh1/Hct1/FZR (OMIM:603619), a regulatory subunit of the anaphase-promoting complex/cyclosome (APC/C) required for anaphase initiation and exit from mitosis; FZR-1 is required for fertility, and also functions redundantly with lin-35/Rb to for normal embryogensis and control of postembryonic cell proliferation; FZR-1 probably regulates the levels of G1 cyclins, degradation of which is critical for G1 arrest.
12	cpf-2	F56A8.6	n/a	chrIII 13,267,824	C. elegans CPF-2 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
13	F23F1.5	F23F1.5	n/a	chrII 30,845	contains similarity to Interpro domains IPR012310 (ATP dependent DNA ligase, central), IPR017336 (Snurportin-1), IPR002652 (Importin-alpha-like, importin-beta-binding region)
14	ZC395.11	ZC395.11	n/a	chrIII 5,286,154
15	C25A1.4	C25A1.4	n/a	chrI 10,171,209	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
16	R04A9.2	R04A9.2	n/a	chrX 374,567	contains similarity to Pfam domains PF02170 (PAZ domain) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
17	AH9.3	AH9.3	n/a	chrX 2,259,841	contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
18	M04F3.2	M04F3.2	n/a	chrI 4,766,635	contains similarity to Bradyrhizobium japonicum 30S ribosomal protein S6.; SW:Q89MW3
19	K01A2.9	K01A2.9	n/a	chrII 316,397	contains similarity to Interpro domain IPR002229 (Blood group Rhesus C/E and D polypeptide)
20	W04A8.5	W04A8.5	n/a	chrI 13,850,230	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
21	ZK686.4	ZK686.4	n/a	chrIII 7,769,518	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR007087 (Zinc finger, C2H2-type)
22	F16B12.6	F16B12.6	n/a	chrX 14,105,057	contains similarity to Mus musculus Neurofilament triplet H protein (200 kDa neurofilament protein)s(Neurofilament heavy polypeptide) (NF-H).; SW:NFH_MOUSE
23	pix-1	K11E4.4	n/a	chrX 13,730,745	C. elegans PIX-1 protein ;
24	C18A3.2	C18A3.2	n/a	chrII 5,719,035	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
25	F56D2.3	F56D2.3	n/a	chrIII 5,585,825
26	Y53C12B.6	Y53C12B.6	n/a	chrII 9,723,099	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
27	T07F10.5	T07F10.5	n/a	chrV 12,866,209	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002168 (Lipase, GDXG, active site), IPR002018 (Carboxylesterase, type B)
28	W03B1.7	W03B1.7	n/a	chrIV 4,337,935	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
29	ZK185.2	ZK185.2	n/a	chrIV 4,539,155	ZK185.2 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK185.2 is predicted to transport Mg(2+) into cells; ZK185.2 is paralogous to K07H8.2 and ZK1053.6, and has no obvious function in mass RNAi assays.
30	T22B11.2	T22B11.2	n/a	chrIV 4,690,180	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
31	T22C1.6	T22C1.6	n/a	chrI 7,944,147	contains similarity to Homo sapiens Alpha-taxilin; ENSEMBL:ENSP00000362711
32	dpy-26	C25G4.5	n/a	chrIV 12,448,610	dpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array.
33	F32B4.1	F32B4.1	n/a	chrI 11,511,408	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
34	T05D4.2	T05D4.2	n/a	chrIII 13,562,369	contains similarity to Mus musculus Similar to SPEER 2.; TR:Q80ZP2
35	M01E5.6	M01E5.6	n/a	chrI 13,299,460	contains similarity to Pfam domain PF02172 KIX domain contains similarity to Interpro domain IPR003101 (Coactivator CBP, KIX)
36	hsr-9	T05F1.6	n/a	chrI 9,628,707	hsr-9 encodes a protein containing a BRCT (BRCA 1 C terminus) domain that is found in proteins that regulate the cell cycle checkpoint in response to DNA damage; HSR-9 activity is required for a normal response to DNA damage caused by gamma-irradiation; loss of HSR-9 function via RNA-mediated interference after gamma-irradiation results in defects in mitotic cell cycle arrest, reduction of apoptosis of pachytene nuclei, and radiation sensitivity of progeny; the expression pattern and subcellular localization of HSR-9 are not yet known.
37	F12F6.8	F12F6.8	n/a	chrIV 11,556,346	contains similarity to Schizosaccharomyces pombe Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylylscyclase).; SW:CYAA_SCHPO
38	F14B4.1	F14B4.1	n/a	chrI 9,268,427	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) , PF00057 (Low-density lipoprotein receptor domain class A) , PF00058 (Low-density lipoprotein receptor repeat class B) (4)contains similarity to Interpro domains IPR000033 (), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding), IPR015943 (WD40/YVTN repeat-like)
39	taf-4	R119.6	n/a	chrI 385,688	taf-4 encodes a TAFII (TBP(TATA-binding protein)-associated factor) that is orthologous to human TAF4 (hTAFII130); TAF-4 is predicted to be a component of the TFIID mRNA transcription complex and is generally required for early embryonic mRNA transcription; consistent with this observation, taf-4(RNAi) results in embryonic lethality at the ~100-cell stage with little cell differentiation, similar to the loss of AMA-1/RNA polymerase II activity; TAF-4 is detected in nuclei in the adult germline, oocytes, and embryo, from the 2-cell stage through early morphogenesis.
40	B0454.9	B0454.9	n/a	chrII 3,053,483	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
41	dpm-1	Y66H1A.2	n/a	chrIV 447,058	dpm-1 encodes a putative catalytic subunit of dolichol phosphate mannosyltransferase, orthologous to budding yeast and human DPM1 (OMIM:603503, mutated in congenital disorder of glycosylation type Ie); in mass RNAi assays, DPM-1 is required for embryonic viability and proper cortical motion in the early embryo.
42	aps-1	F29G9.3	n/a	chrV 6,018,404	aps-1 encodes an adaptin: specifically, it encodes an ortholog of the sigma1 subunit of adaptor protein complex 1 (AP-1).
43	bub-3	Y54G9A.6	n/a	chrII 13,727,744	C. elegans BUB-3 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
44	ZK154.5	ZK154.5	n/a	chrX 7,785,505	contains similarity to Homo sapiens Isoform 4 of Target of Nesh-SH3 precursor; ENSEMBL:ENSP00000373190
45	rpb-4	F43E2.2	n/a	chrII 7,374,771	C. elegans RPB-4 protein; contains similarity to Pfam domain PF03874 RNA polymerase Rpb4 contains similarity to Interpro domains IPR010997 (HRDC-like), IPR005574 (RNA polymerase II, Rpb4), IPR006590 (RNA polymerase II, Rpb4, core)
46	fbxb-74	R08C7.9	n/a	chrIV 4,438,735	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
47	hlh-3	T24B8.6	n/a	chrII 9,086,866	hlh-3 encodes a basic helix-loop-helix transcription factor homologous to Drosophila Achaete-scute; in vitro, HLH-3 can heterodimerize, and bind an E-box-containing probe, with HLH-2, the C. elegans E/daughterless ortholog with which it is coexpressed in the nuclei of embryonic neuronal precursors.
48	Y54E5A.6	Y54E5A.6	n/a	chrI 14,709,596	contains similarity to Pfam domains PF01207 (Dihydrouridine synthase (Dus)) , PF00035 (Double-stranded RNA binding motif) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like), IPR000632 (Yeast Mrs6p protein), IPR001269 (Dihydrouridine synthase, DuS)
49	T10C6.5	T10C6.5	n/a	chrV 16,023,741	contains similarity to Pfam domain PF04889 Cwf15/Cwc15 cell cycle control protein contains similarity to Interpro domain IPR006973 (Cwf15/Cwc15 cell cycle control protein)
50	C56G2.15	C56G2.15	n/a	chrIII 6,367,144	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase), IPR008125 (Streptothricin acetyltransferase)