UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F48A11.2	F48A11.2	4e-40	chrII 198,605
2	clec-238	Y102A5C.17	n/a	chrV 16,952,706	C. elegans CLEC-238 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
3	C29F9.2	C29F9.2	n/a	chrIII 131,349	contains similarity to Homo sapiens Isoform 3 of MAP7 domain-containing protein 1; ENSEMBL:ENSP00000362241
4	T20D4.8	T20D4.8	n/a	chrV 3,406,799	T20D4.8 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T20D4.8 has no clear orthologs in other organisms.
5	F46C3.2	F46C3.2	n/a	chrX 11,417,473	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
6	D1046.3	D1046.3	n/a	chrIV 8,931,564	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier)
7	nhr-230	Y17D7A.1	n/a	chrV 18,849,704	C. elegans NHR-230 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	tat-6	F02C9.3	n/a	chrV 3,131,186	C. elegans TAT-6 protein; contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006539 (Phospholipid-translocating P-type ATPase, flippase), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
9	hap-1	ZC395.7	n/a	chrIII 5,264,428	C. elegans HAP-1 protein; contains similarity to Pfam domain PF01725 Ham1 family contains similarity to Interpro domain IPR002637 (Ham1-like protein)
10	Y32B12C.3	Y32B12C.3	n/a	chrV 16,613,751	contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
11	F21A3.5	F21A3.5	n/a	chrV 15,540,560	contains similarity to Pfam domain PF01966 HD domain contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR006674 (Metal-dependent phosphohydrolase, HD region, subdomain)
12	tag-294	C54H2.3	n/a	chrX 5,761,796	C. elegans TAG-294 protein; contains similarity to Pfam domain PF00641 Zn-finger in Ran binding protein and others contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
13	H12D21.9	H12D21.9	n/a	chrV 14,908,258	contains similarity to Oceanobacillus iheyensis Hypothetical UPF0090 protein OB1594.; SW:YF94_OCEIH
14	fbxa-113	Y113G7B.6	n/a	chrV 20,199,350	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
15	K10C2.2	K10C2.2	n/a	chrX 6,433,006	contains similarity to Interpro domain IPR000832 (GPCR, family 2, secretin-like)
16	T11F1.6	T11F1.6	n/a	chrII 2,945,352	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
17	K07D4.2	K07D4.2	n/a	chrII 4,045,127
18	ztf-8	ZC395.8	n/a	chrIII 5,271,035	C. elegans ZTF-8 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR004355 (Type IV secretion system CagA exotoxin), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
19	F14E5.1	F14E5.1	n/a	chrII 8,418,639	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR016196 (MFS general substrate transporter)
20	sre-29	F57G9.4	n/a	chrII 12,400,560	C. elegans SRE-29 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
21	JC8.5	JC8.5	n/a	chrIV 13,245,638	contains similarity to Pfam domain PF04442 Cytochrome c oxidase assembly protein CtaG / Cox11 contains similarity to Interpro domain IPR007533 (Cytochrome c oxidase assembly protein CtaG/Cox11)
22	gpa-4	T07A9.7	n/a	chrIV 403,531	gpa-4 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASI.
23	B0280.7	B0280.7	n/a	chrIII 7,111,015
24	sdz-34	Y73C8C.7	n/a	chrV 3,108,727	C. elegans SDZ-34 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000533 (Tropomyosin), IPR011016 (Zinc finger, variant RING-type)
25	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
26	sqv-7	C52E12.3	n/a	chrII 7,011,690	The sqv-7 gene encodes a nucleotide-sugar transporter of the Golgi membrane, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-7 promotes glycosaminoglycan biosynthesis by translocating UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-galactose into the lumen of the Golgi apparatus; SQV-7 is biochemically active when transgenically expressed in yeast or mammalian Golgi membranes; the common requirement for SQV-7 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
27	W04A8.1	W04A8.1	n/a	chrI 13,837,656	W04A8.1 encodes a protein weakly similar to human microcephalin (MCPH1; OMIM:607117, mutated in primary microcephaly); while their primary sequence similarity is very subtle (only being detectable with psi-BLAST on NCBI-nr, using C. briggsae CBG13622 as a query sequence), both W04A8.1 and microcephalin has similar ordering of BRCT domains (one N-terminal, two C-terminal); W04A8.1 has no obvious function in mass RNAi screens.
28	srx-133	F09F3.4	n/a	chrV 13,849,303	C. elegans SRX-133 protein ;
29	srw-12	C41G6.2	n/a	chrV 15,237,968	C. elegans SRW-12 protein ;
30	F40E3.6	F40E3.6	n/a	chrI 2,651,225
31	C34D4.13	C34D4.13	n/a	chrIV 7,133,813
32	F21E9.2	F21E9.2	n/a	chrX 1,329,400
33	ccb-2	W10C8.1	n/a	chrI 2,848,257	C. elegans CCB-2 protein; contains similarity to Pfam domains PF00774 (Dihydropyridine sensitive L-type calcium channel (Beta subunit)) (2), PF00018 (SH3 domain) contains similarity to Interpro domains IPR000584 (Voltage-dependent calcium channel, L-type, beta subunit), IPR001452 (Src homology-3)
34	fbxa-56	T12B5.7	n/a	chrIII 937,668	C. elegans FBXA-56 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
35	srd-17	Y2H9A.2	n/a	chrV 13,431,663	C. elegans SRD-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	T23F6.2	T23F6.2	n/a	chrIV 12,722,330
37	C46H11.1	C46H11.1	n/a	chrI 5,055,865
38	D1005.6	D1005.6	n/a	chrX 1,463,763
39	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
40	srd-50	F15A2.4	n/a	chrX 13,480,135	C. elegans SRD-50 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	rpb-6	C06A1.5	n/a	chrII 10,579,552	C. elegans RPB-6 protein; contains similarity to Pfam domain PF01192 RNA polymerase Rpb6 contains similarity to Interpro domains IPR006110 (RNA polymerase Rpb6), IPR002048 (Calcium-binding EF-hand), IPR006111 (DNA-directed RNA polymerase, 14 to 18 kDa subunit), IPR012293 (RNA polymerase subunit, RPB6/omega)
42	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
43	sra-33	B0304.6	n/a	chrII 4,535,979	C. elegans SRA-33 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
44	srx-121	C04E12.8	n/a	chrV 3,371,855	C. elegans SRX-121 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
45	T17A3.9	T17A3.9	n/a	chrIII 152,890
46	bli-5	F45G2.5	n/a	chrIII 13,428,598	bli-5 encodes a protease inhibitor that affects the integrity of the cuticle and the development of the bursa in the adult male.
47	rab-33	F43D9.2	n/a	chrIII 10,501,953	C. elegans RAB-33 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR000694 (Proline-rich region), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
48	W02B8.1	W02B8.1	n/a	chrII 13,900,226
49	F25H2.3	F25H2.3	n/a	chrI 10,548,642	contains similarity to Interpro domain IPR002110 (Ankyrin)
50	B0207.8	B0207.8	n/a	chrI 5,951,441