UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F46C8.1	F46C8.1	2e-47	chrX 7,550,722
2	F38B2.3	F38B2.3	n/a	chrX 11,283,730	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
3	F58G1.6	F58G1.6	n/a	chrII 12,941,277	contains similarity to Pfam domain PF02752 Arrestin (or S-antigen), C-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal)
4	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
5	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
6	set-16	T12D8.1	n/a	chrIII 13,650,157	C. elegans SET-16 protein ;
7	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
8	F01G10.9	F01G10.9	n/a	chrIV 10,257,677	contains similarity to Interpro domain IPR000694 (Proline-rich region)
9	flr-1	F02D10.5	n/a	chrX 13,454,529	flr-1 encodes an ion channel that belongs to the DEG/ENaC sodium channel superfamily; flr-1 activity is essential for normal defecation rhythm, growth rates, expulsion, and dauer larvae formation; a rescuing FLR-1::GFP reporter is expressed in the intestine from embryonic to adult stages where it localizes to the membranes facing the inner lumen as well as to part of the lateral membrane between intestinal cells.
10	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
11	dpm-3	F28D1.11	n/a	chrIV 12,391,825	dpm-3 encodes a putative regulatory subunit of dolichol phosphate mannosyltransferase, orthologous to human DPM3 (OMIM:605951); in mass RNAi assays, DPM-3 is required for normal body size, fertility, and health.
12	zyg-8	Y79H2A.11	n/a	chrIII 12,066,888	The zyg-8 gene encodes a protein with a doublecortin-like domain and a protein kinase domain; mutations of zyg-8 impair mitosis at the one-cell embryonic stage, which is normally asymmetrical, but which fails to show proper asymmetry in zyg-8 mutant embryos.
13	T15D6.4	T15D6.4	n/a	chrI 12,375,417	contains similarity to Aedes aegypti N-acetyllactosaminide beta-1,3-n-acetylglucosaminyltransferase.; TR:Q175J5
14	ZC513.2	ZC513.2	n/a	chrV 8,055,592	contains similarity to Pfam domain PF01273 LBP / BPI / CETP family, N-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
15	sul-1	K09C4.8	n/a	chrX 3,269,056	sul-1 encodes a member of the sulfatase family.
16	ZK154.5	ZK154.5	n/a	chrX 7,785,505	contains similarity to Homo sapiens Isoform 4 of Target of Nesh-SH3 precursor; ENSEMBL:ENSP00000373190
17	his-34	F17E9.9	n/a	chrIV 8,336,138	his-34 encodes an H2B histone; his-34 is contained within the histone gene cluster HIS5.
18	F08D12.7	F08D12.7	n/a	chrII 2,768,193	F08D12.7 encodes a novel protein conserved amongst Caenorhaditis species; although loss of F08D12.7 activity via RNAi results in no obvious defects, F08D12.7 transcripts are enriched in L1-stage muscle and upregulated in L2 larvae in response to overexpression of hlh-2 and hlh-8; in addition, in analyses of the early embryonic transcriptome, F08D12.7 transcripts are classified as strictly maternal; an F08D12.7::gfp reporter fusion is expressed in the vm1 and vm2 vulval muscles, the intestinal and anal depressor muscles, the hypodermis, distal tip cell, ventral nerve cord, head and tail neurons, and body wall muscle.
19	F22F7.2	F22F7.2	n/a	chrV 2,125,082	contains similarity to Pfam domain PF03435 Saccharopine dehydrogenase contains similarity to Interpro domains IPR005097 (Saccharopine dehydrogenase), IPR016040 (NAD(P)-binding)
20	pqn-67	T16G1.1	n/a	chrV 12,926,198	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
21	ram-5	T24C2.1	n/a	chrX 14,553,138	ram-5 encodes a novel transmembrane protein; during male tail development, ram-5 activity is required in ray structural cells for proper sensory ray morphogenesis; a RAM-5::GFP fusion protein is expressed in all of the ray structural cells of the male tail, as well as additional sensory support cells in both hermaphrodites and males, including those of the inner labial sensilla as well as the ADE, PDE, and phasmid socket cells.
22	C46F11.4	C46F11.4	n/a	chrIII 3,661,086	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
23	C03F11.2	C03F11.2	n/a	chrX 5,395,712	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
24	E02H9.1	E02H9.1	n/a	chrIII 2,468,952
25	ttb-1	W03F9.5	n/a	chrV 160,090	C. elegans TTB-1 protein; contains similarity to Pfam domains PF00382 (Transcription factor TFIIB repeat) (2), PF08271 (TFIIB zinc-binding) contains similarity to Interpro domains IPR006670 (Cyclin), IPR000812 (Transcription factor TFIIB related), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR013150 (Transcription factor TFIIB, cyclin-related), IPR013137 (Zinc finger, TFIIB-type)
26	sru-42	C55A1.8	n/a	chrV 15,651,414	C. elegans SRU-42 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR002208 (SecY protein), IPR003839 (Protein of unknown function DUF215)
27	C14C6.13	C14C6.13	n/a	chrV 573,386
28	his-55	F54E12.1	n/a	chrIV 11,338,029	his-55 encodes an H3 histone; by homology, HIS-55 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-55 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
29	mtm-5	H28G03.6	n/a	chrX 5,239,010	C. elegans MTM-5 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF06602 (Myotubularin-related) , PF02893 (GRAM domain) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR010569 (Myotubularin-related), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR005113 (uDENN), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR001194 (DENN), IPR004182 (GRAM)
30	C24H10.2	C24H10.2	n/a	chrX 5,065,438
31	F40G9.1	F40G9.1	n/a	chrIII 196,177	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
32	ing-3	Y51H1A.4	n/a	chrII 13,879,211	Y51H1A.4 is orthologous to the human gene P33ING1B (ING1; OMIM:601566), which when mutated leads to disease.
33	T22B11.2	T22B11.2	n/a	chrIV 4,690,180	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
34	F49B2.3	F49B2.3	n/a	chrI 14,311,927	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region)
35	F48C1.4	F48C1.4	n/a	chrI 5,313,536
36	F18A12.7	F18A12.7	n/a	chrII 3,412,942	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
37	F36D1.1	F36D1.1	n/a	chrI 11,278,248	contains similarity to Interpro domain IPR006578 (MADF)
38	glb-10	C29F5.7	n/a	chrII 6,308,800	glb-10 encodes a globin; glb-10 is expressed in pharynx, intestine, vulval muscle, and many neurons, with at least some subcellular localization to synapses; however, glb-10 has no obvious function in mass RNAi assays.
39	C15C7.6	C15C7.6	n/a	chrX 3,169,031	contains similarity to Interpro domain IPR003945 (NADH-plastoquinone oxidoreductase, chain 5)
40	K06G5.3	K06G5.3	n/a	chrX 14,221,334	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
41	F57B10.5	F57B10.5	n/a	chrI 6,563,176	contains similarity to Pfam domain PF01105 emp24/gp25L/p24 family/GOLD contains similarity to Interpro domains IPR009038 (GOLD), IPR000348 (emp24/gp25L/p24)
42	ctg-1	H06O01.3	n/a	chrI 7,007,341	C. elegans CTG-1 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
43	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
44	sri-11	T22H2.3	n/a	chrI 11,696,802	C. elegans SRI-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
45	C34E7.4	C34E7.4	n/a	chrX 12,933,527	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
46	his-65	H02I12.7	n/a	chrIV 11,401,254	his-65 encodes an H2A histone.
47	dpm-1	Y66H1A.2	n/a	chrIV 447,058	dpm-1 encodes a putative catalytic subunit of dolichol phosphate mannosyltransferase, orthologous to budding yeast and human DPM1 (OMIM:603503, mutated in congenital disorder of glycosylation type Ie); in mass RNAi assays, DPM-1 is required for embryonic viability and proper cortical motion in the early embryo.
48	fbxb-47	F58E1.14	n/a	chrII 1,702,944	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
49	Y39A1C.1	Y39A1C.1	n/a	chrIII 10,857,346	contains similarity to Xylella fastidiosa Hypothetical protein Xf0776.; TR:Q9PFA2
50	C34F6.5	C34F6.5	n/a	chrX 11,208,547	contains similarity to Homo sapiens Histone acetyltransferase MORF beta; ENSEMBL:ENSP00000287239