UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	taf-11.3	F43D9.5	1.9999999999999998e-86	chrIII 10,504,535	The taf-11.3 gene encodes an ortholog of human TATA-binding protein associated factor TAF11 (TAFII28, OMIM:600772) that is a component of the TFIID general transcription factor that recognizes the transcription start site; TAF-11.3 is required for proper post-embryonic development.
2	Y52B11A.9	Y52B11A.9	n/a	chrI 11,036,452	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR005824 (KOW), IPR002358 (Ribosomal protein L6, conserved site-1), IPR007087 (Zinc finger, C2H2-type)
3	T14G10.8	T14G10.8	n/a	chrIV 10,146,609	contains similarity to Homo sapiens Splice isoform 1 of P08235 Mineralocorticoid receptor; ENSEMBL:ENSP00000281330
4	Y54E2A.6	Y54E2A.6	n/a	chrII 14,768,030	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) (2), PF00271 (Helicase conserved C-terminal domain) (2), PF02889 (Sec63 Brl domain) (2)contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004179 (Sec63), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
5	K02E7.4	K02E7.4	n/a	chrII 1,073,572	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domain IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
6	E02H9.4	E02H9.4	n/a	chrIII 2,457,255	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
7	T02G6.6	T02G6.6	n/a	chrI 11,821,054	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
8	F58F6.3	F58F6.3	n/a	chrIV 1,375,965
9	C41D11.4	C41D11.4	n/a	chrI 4,442,876
10	W09C5.9	W09C5.9	n/a	chrI 13,661,170	contains similarity to Lactococcus lactis Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartatestranscarbamylase) (ATCase).; SW:PYRB_LACLA
11	F44E5.3	F44E5.3	n/a	chrII 11,763,830	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000304160
12	F44E5.2	F44E5.2	n/a	chrII 11,770,321	contains similarity to Pfam domain PF00560 Leucine Rich Repeat
13	nhr-179	F16B4.11	n/a	chrV 1,616,853	C. elegans NHR-179 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	srh-233	Y113G7A.1	n/a	chrV 20,046,361	C. elegans SRH-233 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	F08C6.5	F08C6.5	n/a	chrX 7,560,915	contains similarity to Interpro domain IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site)
16	Y63D3A.8	Y63D3A.8	n/a	chrI 14,116,402	contains similarity to Interpro domains IPR002114 (Phosphotransferase system, HPr serine phosphorylation site), IPR006634 (TRAM, LAG1 and CLN8 homology)
17	Y17D7B.5	Y17D7B.5	n/a	chrV 18,775,675	contains similarity to Interpro domain IPR006583 (CW)
18	sprr-2	F42D1.3	n/a	chrX 14,802,137	C. elegans SPRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
19	fbxa-95	F28F8.4	n/a	chrV 15,572,053	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
20	lin-1	C37F5.1	n/a	chrIV 2,288,106	lin-1 encodes an Ets-domain-containing transcription factor that is a member of the ETS gene family that includes human ELK1, 3, and 4 (OMIM:600247); LIN-1 functions as a general effector of MAP kinase-mediated signaling; when MAP kinase is inactive, LIN-1 forms a complex with LIN-31/WH that inhibits vulval cell fate specification; upon MAP kinase activation (vulval induction), LIN-1 is phosphorylated, dissociates from LIN-31, and becomes inactive, thus allowing for vulval development.
21	F47E1.1	F47E1.1	n/a	chrX 9,075,645
22	srbc-17	C45H4.3	n/a	chrV 2,178,415	C. elegans SRBC-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
23	T05C1.5	T05C1.5	n/a	chrII 4,490,625	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
24	R119.5	R119.5	n/a	chrI 391,462	contains similarity to Pfam domain PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) contains similarity to Interpro domain IPR000682 (Protein-L-isoaspartate(D-aspartate) O-methyltransferase)
25	str-74	C14H10.4	n/a	chrX 10,240,354	C. elegans STR-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	str-134	C05E4.6	n/a	chrV 744,563	C. elegans STR-134 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	R148.2	R148.2	n/a	chrIII 3,184,321
28	K09A11.1	K09A11.1	n/a	chrX 13,263,425	contains similarity to Pfam domains PF05699 (hAT family dimerisation domain) , PF02892 (BED zinc finger) contains similarity to Interpro domains IPR008906 (HAT dimerisation), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
29	nhr-271	T03E6.3	n/a	chrV 16,579,462	C. elegans NHR-271 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	EEED8.4	EEED8.4	n/a	chrII 5,410,795	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
31	grl-18	T05C3.4	n/a	chrV 5,487,265	grl-18 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
32	F53F8.1	F53F8.1	n/a	chrV 20,682,534	The F53F8.1 gene encodes a homolog of human WT1, which when mutated leads to Wilms tumour (OMIM:194070).
33	W06G6.9	W06G6.9	n/a	chrV 16,646,169	contains similarity to Ralstonia solanacearum Hypothetical protein RSc2317.; TR:Q8XX01
34	srz-74	K03D3.1	n/a	chrIV 16,330,219	C. elegans SRZ-74 protein ;
35	Y32B12C.1	Y32B12C.1	n/a	chrV 16,607,269	contains similarity to Interpro domain IPR002625 (Smr protein/MutS2 C-terminal)
36	ing-3	Y51H1A.4	n/a	chrII 13,879,211	Y51H1A.4 is orthologous to the human gene P33ING1B (ING1; OMIM:601566), which when mutated leads to disease.
37	frk-1	T04B2.2	n/a	chrIV 10,044,780	frk-1 encodes a non-receptor tyrosine kinase orthologous to the human proto-oncogene Fer; frk-1 is an essential gene required early for embryonic cell proliferation and later in embryonic epidermal cells for enclosure, morphogenesis and late stages of differentiation; FRK-1's role in embryonic development is independent of its kinase domain, and when expressed in cultured mammalian cells, FRK-1 disrupts cell adhesion; FRK-1 is initially expressed in all cells of the early embryo where it localizes to nuclei and points of cell-cell contact; later expression is seen in epithelial cells, body wall muscle, and the adult germline, including mature sperm; FRK-1 expression in epidermal cells requires activity of the ELT-1 GATA transcription factor, and FRK-1 localization to the plasma membrane requires PAT-3/Beta-integrin, JAC-1/p120 catenin, and HMP-2/Beta-catenin with which FRK-1 interacts in vitro.
38	C50E3.2	C50E3.2	n/a	chrV 7,610,647	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
39	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
40	athp-1	C44B9.4	n/a	chrIII 10,887,899	C. elegans ATHP-1 protein; contains similarity to Pfam domains PF02178 (AT hook motif) (2), PF00628 (PHD-finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region), IPR000253 (Forkhead-associated), IPR011011 (Zinc finger, FYVE/PHD-type)
41	C10E2.4	C10E2.4	n/a	chrX 16,750,349
42	srx-13	C44B12.4	n/a	chrIV 1,116,817	C. elegans SRX-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
43	ZK1098.5	ZK1098.5	n/a	chrIII 9,526,211	ZK1098.5 encodes a unfamiliar protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
44	rod-1	F55G1.4	n/a	chrIV 7,481,969	C. elegans ROD-1 protein ; contains similarity to Caenorhabditis remanei Putative RoughDeal (Fragment).; TR:Q4TTM7
45	F41C6.2	F41C6.2	n/a	chrX 6,870,966
46	srw-26	T05G11.3	n/a	chrV 15,931,865	C. elegans SRW-26 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
47	F54E7.6	F54E7.6	n/a	chrIII 5,660,439
48	his-12	ZK131.6	n/a	chrII 13,821,298	his-12 encodes an H2A histone; his-12 is contained within the histone gene cluster HIS3.
49	ZK546.5	ZK546.5	n/a	chrII 4,936,745	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
50	R10D12.7	R10D12.7	n/a	chrV 13,950,209	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)