UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fis-1	F41G3.4	3e-59	chrII 6,755,453	C. elegans FIS-1 protein; contains similarity to Interpro domains IPR016543 (Tetratricopeptide repeat 11 Fission 1 protein), IPR011990 (Tetratricopeptide-like helical)
2	K09D9.3	K09D9.3	n/a	chrV 4,020,029
3	Y56A3A.2	Y56A3A.2	n/a	chrIII 11,856,255	contains similarity to Pfam domain PF02163 Peptidase family M50 contains similarity to Interpro domains IPR008915 (Peptidase M50), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001193 (Peptidase M50, mammalian sterol-regulatory element binding protein)
4	F21D9.4	F21D9.4	n/a	chrV 19,255,280	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
5	Y116A8C.29	Y116A8C.29	n/a	chrIV 17,094,627	contains similarity to Homo sapiens Class-I MHC-restricted T cell associated molecule; ENSEMBL:ENSP00000227348
6	col-147	T06E4.4	n/a	chrV 9,632,778	C. elegans COL-147 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
7	osm-6	R31.3	n/a	chrV 11,925,995	osm-6 encodes a novel protein that is orthologous to the IFT52 component of the intraflagellar transport particle; osm-6 activity is required cell autonomously for proper sensory cilium structure and thus for normal ciliated sensory neuron function; OSM-6 is a component of the intraflagellar transport particle subcomplex B, and OSM-6::GFP reporter fusions are expressed exclusively in ciliated sensory neurons.
8	T05C1.2	T05C1.2	n/a	chrII 4,482,363
9	F25B3.2	F25B3.2	n/a	chrV 9,578,510	contains similarity to Lactococcus lactis Oligopeptide transport system permease protein oppC.; SW:OPPC_LACLA
10	R10F2.4	R10F2.4	n/a	chrIII 2,921,110	contains similarity to Interpro domain IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal)
11	T21G5.2	T21G5.2	n/a	chrI 6,870,894
12	T25D1.3	T25D1.3	n/a	chrX 16,506,246	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
13	eat-2	Y48B6A.4	n/a	chrII 14,169,168	eat-2 encodes a ligand-gated ion channel subunit most closely related to the non-alpha-subunits of nicotinic acetylcholine receptors (nAChR); EAT-2 functions postsynaptically in pharyngeal muscle to regulate the rate of pharyngeal pumping; eat-2 is also required for normal life span and defecation; a functional EAT-2::GFP fusion protein localizes to two small dots near the junction of pharyngeal muscles pm4 and pm5, which is the site of the posterior-most MC motor neuron processes and the MC synapse; eat-2 genetically interacts with eat-18, which encodes a predicted novel transmembrane protein expressed in pharyngeal muscle and required for proper function of pharyngeal nicotonic receptors.
14	T02H6.8	T02H6.8	n/a	chrII 681,180
15	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.
16	C33E10.5	C33E10.5	n/a	chrX 17,276,148	contains similarity to Interpro domain IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
17	scl-23	B0545.3	n/a	chrIV 88,065	C. elegans SCL-23 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR014044 (SCP-like extracellular)
18	E01G6.2	E01G6.2	n/a	chrX 12,257,730	contains similarity to Streptomyces coelicolor;Streptomyces lividans Putative secreted protein (Putative TWIN ARGININ translocationsreceptor).; TR:Q9RJ68
19	R10D12.1	R10D12.1	n/a	chrV 13,933,592	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001958 (Tetracycline resistance protein, TetA), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
20	W06G6.10	W06G6.10	n/a	chrV 16,646,964	contains similarity to Escherichia coli O157:H7 C4-type zinc finger protein (TraR family).; TR:Q8X2P7
21	F13H8.9	F13H8.9	n/a	chrII 6,280,371	contains similarity to Pfam domain PF00266 Aminotransferase class-V contains similarity to Interpro domains IPR016454 (Cysteine desulphurase, NifS), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
22	Y48B6A.10	Y48B6A.10	n/a	chrII 14,215,677	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
23	C26E6.12	C26E6.12	n/a	chrIII 4,931,357	contains similarity to Pfam domains PF01018 (GTP1/OBG) , PF01926 (GTPase of unknown function) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR014100 (GTP-binding protein Obg/CgtA), IPR006169 (GTP1/OBG subdomain), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG)
24	T16A1.3	T16A1.3	n/a	chrII 2,084,511
25	H36L18.1	H36L18.1	n/a	chrX 12,650,135	contains similarity to Pfam domains PF00413 (Matrixin) , PF00045 (Hemopexin) (3)contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin)
26	pqn-84	Y41C4A.5	n/a	chrIII 11,701,451	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
27	spe-12	T02E1.1	n/a	chrI 8,225,426	C. elegans SPE-12 protein ;
28	srxa-15	Y44A6B.2	n/a	chrV 20,638,710	C. elegans SRXA-15 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
29	T28D6.7	T28D6.7	n/a	chrIII 11,345,403	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
30	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	C40A11.8	C40A11.8	n/a	chrII 2,150,922
32	R02F11.2	R02F11.2	n/a	chrV 4,795,145
33	Y53C10A.5	Y53C10A.5	n/a	chrI 12,000,702	contains similarity to Interpro domain IPR000608 (Ubiquitin-conjugating enzyme, E2)
34	F28B4.1	F28B4.1	n/a	chrX 3,205,615
35	tbx-11	F40H6.4	n/a	chrIII 6,046,285	tbx-11 encodes a T-box transcription factor that is orthologous to members of the Tbx2 subfamily of T-box transcription factors; by homology, TBX-11 is predicted to function in transcriptional regulation during cellular differentiation, potentially as both an activator and a repressor; however, as loss of tbx-11 function via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of tbx-11 in C. elegans development and/or behavior is not yet known.
36	fox-1	T07D1.4	n/a	chrX 2,448,279	fox-1 encodes an RNA-binding protein of the RNA recognition motif (RRM) superfamily of ribonucleic acid binding proteins; during C. elegans development, FOX-1 functions redundantly with other numerator elements to effect proper dosage compensation in the early embryo; in influencing dosage compensation, FOX-1 likely acts via post-transcriptional regulation of xol-1 mRNA levels; in addition to its role in dosage compensation, fox-1 activity is also required for normal male mating behavior; Western analysis and lacZ reporter constructs indicate that FOX-1 is expressed throughout the life cycle, beginning at the 18-20-cell stage of embryogenesis and continuing on through larval stages and into adult hermaphrodites and males; while early embryonic expression of fox-1 is ubiquitous, postembryonic expression is limited to a subset of head and tail neurons.
37	C44E4.2	C44E4.2	n/a	chrI 4,632,370	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
38	Y69H2.9	Y69H2.9	n/a	chrV 18,703,400	contains similarity to Grapevine leafroll-associated virus 3 Polymerase (Fragment).; TR:Q8V2G8
39	C17D12.7	C17D12.7	n/a	chrI 11,607,946	contains similarity to Saccharomyces cerevisiae Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern; SGD:YGL174W
40	ZK1055.2	ZK1055.2	n/a	chrV 6,593,054	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
41	Y75B8A.25	Y75B8A.25	n/a	chrIII 12,278,010	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
42	Y7A5A.6	Y7A5A.6	n/a	chrX 15,798,435	contains similarity to Schizosaccharomyces pombe Putative transcriptional regulatory protein, phd finger.; TR:Q9HDV4
43	C50A2.4	C50A2.4	n/a	chrIV 1,160,591	contains similarity to Pfam domain PF00178 Ets-domain contains similarity to Interpro domains IPR000418 (Ets), IPR011991 (Winged helix repressor DNA-binding)
44	spe-4	ZK524.1	n/a	chrI 7,455,774	spe-4 encodes a transmembrane protein that is a divergent member of the presenilin family of proteins that have been implicated in early-onset Alzheimer's disease (OMIM:104300); spe-4 activity is required for proper formation and function of the fibrous body-membranous organelles that are asymmetrically localized to spermatids during spermatogeneis; spe-4 is also required for proper partitioning of tubulin as spermatids bud from the residual body; spe-4 localizes to the fibrous body-membranous organelles of developing spermatocytes and also to the spermatozoon cell body.
45	ZK1053.4	ZK1053.4	n/a	chrI 13,243,185	contains similarity to Schizosaccharomyces pombe Nucleoporin nup124 (Nuclear pore protein nup124).; SW:N124_SCHPO
46	C46E10.5	C46E10.5	n/a	chrII 3,712,130
47	fbxb-107	F29A7.2	n/a	chrII 2,760,240	C. elegans FBXB-107 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
48	srsx-30	C51E3.5	n/a	chrV 10,159,536	C. elegans SRSX-30 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
49	dsl-2	W09G12.1	n/a	chrIV 1,203,808	dsl-2 encodes a putative transmembrane protein whose extracellular domain has single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-2 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
50	T04D1.2	T04D1.2	n/a	chrI 4,681,214	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.