UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F40G9.7	F40G9.7	5e-92	chrIII 165,986
2	C48B6.3	C48B6.3	n/a	chrI 6,915,508	contains similarity to Homo sapiens UPF0472 protein C16orf72; ENSEMBL:ENSP00000331720
3	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
4	T20D3.8	T20D3.8	n/a	chrIV 9,342,540	contains similarity to Pfam domain PF06432 Phosphatidylinositol N-acetylglucosaminyltransferase contains similarity to Interpro domain IPR009450 (Phosphatidylinositol N-acetylglucosaminyltransferase)
5	W06D11.1	W06D11.1	n/a	chrX 12,294,462
6	ZK1248.11	ZK1248.11	n/a	chrII 5,828,127	contains similarity to Xenopus laevis E3 SUMO-protein ligase NSE2 (EC 6.-.-.-) (Non-structural maintenancesof chromosomes element 2 homolog) (Non-SMC element 2 homolog).; SW:Q7ZXH2
7	M110.3	M110.3	n/a	chrII 8,215,496	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
8	F10A3.1	F10A3.1	n/a	chrV 16,140,754	F10A3.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F10A3.1 is worm-specific, with obvious homologs only in C. elegans; F10A3.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
9	2L52.1	2L52.1	n/a	chrII 3,265	2L52.1 encodes a protein with sequence similarity to GLI-family zinc-finger transcription factors; deletion mutations in 2L52.1 are reported to be homozygous viable.
10	F35H10.6	F35H10.6	n/a	chrIV 8,300,273	contains similarity to Pfam domain PF02996 Prefoldin subunit contains similarity to Interpro domains IPR004127 (Prefoldin alpha-like), IPR009053 (Prefoldin)
11	F55C5.4	F55C5.4	n/a	chrV 12,273,750	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
12	T25B9.8	T25B9.8	n/a	chrIV 10,767,369	contains similarity to Interpro domain IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
13	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
14	Y5F2A.4	Y5F2A.4	n/a	chrIV 11,077,311	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
15	kbp-5	C34B2.2	n/a	chrI 10,687,701	C. elegans KBP-5 protein ;
16	tbx-36	ZK829.5	n/a	chrIV 11,951,305	C. elegans TBX-36 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
17	fbxb-67	F49B2.2	n/a	chrI 14,297,764	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
18	T12F5.1	T12F5.1	n/a	chrI 3,742,059
19	C02B10.2	C02B10.2	n/a	chrIV 5,090,651	contains similarity to Homo sapiens SNARE-associated protein Snapin; ENSEMBL:ENSP00000357674
20	ekl-5	Y26E6A.1	n/a	chrX 13,915,941	C. elegans EKL-5 protein; contains similarity to Interpro domains IPR001579 (Glycoside hydrolase, chitinase active site), IPR006642 (Zinc finger, Rad18-type putative)
21	F43D2.1	F43D2.1	n/a	chrV 14,613,051	contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR015429 (Transcription regulator cyclin)
22	mom-5	T23D8.1	n/a	chrI 9,967,489	mom-5 encodes one of four C. elegans members of the Frizzled (Fz) family of seven transmembrane receptors; during development, MOM-5 activity is required for asymmetric cell division in the early embryo as well as for asymmetric cell division during neuronal development; MOM-5::GFP is enriched at the posterior pole of cells prior to division and during later stages of embryogenesis, is found at the leading edges of epidermal cells during ventral enclosure; in neuroblasts, MOM-5 is required for proper subcellular distribution of DSH-2 to the cortex.
23	Y49A10A.1	Y49A10A.1	n/a	chrX 10,359,445	contains similarity to Pfam domain PF06565 Repeat of unknown function (DUF1126) contains similarity to Interpro domains IPR010554 (Protein of unknown function DUF1126), IPR006602 (Region of unknown function DM10)
24	W02D7.5	W02D7.5	n/a	chrV 8,298,506	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
25	pie-1	Y49E10.14	n/a	chrIII 12,427,870	pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6.
26	his-74	W05B10.1	n/a	chrV 12,659,997	C. elegans HIS-74 protein; contains similarity to Pfam domain PF00125 Core histone H2A/H2B/H3/H4 contains similarity to Interpro domains IPR000164 (Histone H3), IPR009072 (Histone-fold), IPR007125 (Histone core)
27	F42A6.5	F42A6.5	n/a	chrIV 3,331,304	contains similarity to Interpro domain IPR001357 (BRCT)
28	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.
29	F53F8.5	F53F8.5	n/a	chrV 20,697,686	contains similarity to Pfam domain PF00536 SAM domain (Sterile alpha motif) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR013761 (Sterile alpha motif-type), IPR001660 (Sterile alpha motif SAM)
30	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
31	Y40B1B.7	Y40B1B.7	n/a	chrI 13,427,466	contains similarity to Rattus norvegicus Coiled-coil domain-containing protein 86 (Cytokine-induced proteinswith coiled-coil domain).; SW:Q5XIB5
32	T23G11.4	T23G11.4	n/a	chrI 7,694,776	contains similarity to Pfam domain PF07052 Hepatocellular carcinoma-associated antigen 59 contains similarity to Interpro domain IPR010756 (Hepatocellular carcinoma-associated antigen 59)
33	M02B7.4	M02B7.4	n/a	chrIV 3,802,482	contains similarity to Pfam domain PF08660 Oligosaccharide biosynthesis protein Alg14 like contains similarity to Interpro domain IPR013969 (Oligosaccharide biosynthesis protein Alg14 like)
34	lrr-1	F33G12.4	n/a	chrII 5,035,345	F33G12.4 encodes a leucine rich repeat-containing protein; loss of F33G12.4 activity via large-scale RNAi indicates that F33G12.4 is essential for embryonic and larval development.
35	R10E4.6	R10E4.6	n/a	chrIII 4,294,138
36	F52C6.4	F52C6.4	n/a	chrII 1,923,563	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
37	B0304.2	B0304.2	n/a	chrII 4,524,073
38	mdt-22	ZK970.3	n/a	chrII 10,301,446	C. elegans MDT-22 protein; contains similarity to Pfam domain PF06179 Surfeit locus protein 5 contains similarity to Interpro domain IPR009332 (Surfeit locus 5)
39	dro-1	F53A2.5	n/a	chrIII 13,342,882	C. elegans DRO-1 protein; contains similarity to Pfam domains PF00808 (Histone-like transcription factor (CBF/NF-Y) and archaeal histone) , PF00125 (Core histone H2A/H2B/H3/H4) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR007125 (Histone core), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
40	C33H5.6	C33H5.6	n/a	chrIV 7,776,604	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR000664 (Lethal(2) giant larvae protein), IPR015943 (WD40/YVTN repeat-like)
41	C17H12.2	C17H12.2	n/a	chrIV 6,788,223	contains similarity to Drosophila melanogaster Flybase gene name is CG7289-PA;; FLYBASE:CG7289
42	M151.3	M151.3	n/a	chrII 3,629,023	contains similarity to Homo sapiens Isoform 2 of Girdin; ENSEMBL:ENSP00000263630
43	F36A2.8	F36A2.8	n/a	chrI 8,811,005	contains similarity to Pfam domain PF05005 Janus/Ocnus family (Ocnus) contains similarity to Interpro domain IPR007702 (Janus/Ocnus)
44	C56C10.9	C56C10.9	n/a	chrII 6,591,647	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
45	F27B3.5	F27B3.5	n/a	chrIII 6,560,937	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
46	K07F5.12	K07F5.12	n/a	chrIV 9,856,975	contains similarity to Pfam domain PF07857 CEO family (DUF1632) contains similarity to Interpro domain IPR012435 (Protein of unknown function DUF1632)
47	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
48	try-1	ZK546.15	n/a	chrII 4,948,807	C. elegans TRY-1 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine), IPR008256 (Peptidase S1B, glutamyl endopeptidase I)
49	C42C1.8	C42C1.8	n/a	chrIV 12,292,136	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
50	C15C6.4	C15C6.4	n/a	chrI 12,214,144	C15C6.4 encodes an ortholog of Pop4 (Rpp29), a protein subunit of the endoribonuclease RNAse P, which cleaves tRNA precursors to produce their mature 5' end; C15C6.4 is evolutionarily ubiquitous among eukaryotes.