UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F38B6.4	F38B6.4	0	chrX 6,677,310	contains similarity to Pfam domains PF02844 (Phosphoribosylglycinamide synthetase, N domain) , PF02769 (AIR synthase related protein, C-terminal domain) , PF02843 (Phosphoribosylglycinamide synthetase, C domain) , PF01071 (Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain) , PF00551 (Formyl transferase) , PF00586 (AIR synthase related protein, N-terminal domain) contains similarity to Interpro domains IPR016185 (PreATP-grasp-like fold), IPR011761 (ATP-grasp fold), IPR004733 (Phosphoribosylformylglycinamidine cyclo-ligase), IPR002376 (Formyl transferase, N-terminal), IPR016188 (PurM, N-terminal-like), IPR000728 (AIR synthase related protein), IPR004607 (Phosphoribosylglycinamide formyltransferase), IPR013815 (ATP-grasp fold, subdomain 1), IPR010918 (AIR synthase related protein, C-terminal), IPR013816 (ATP-grasp fold, subdomain 2), IPR013817 (Pre-ATP-grasp fold), IPR011054 (Rudiment single hybrid motif), IPR000115 (Phosphoribosylglycinamide synthetase)
2	K09C4.10	K09C4.10	n/a	chrX 3,278,116	contains similarity to Staphylococcus aureus Serine-rich adhesin for platelets precursor (Staphylococcus aureusssurface protein A).; SW:Q7A362
3	C33G3.4	C33G3.4	n/a	chrX 14,073,660	C33G3.4 is orthologous to the human gene BETA-MANNOSIDASE (MANBA; OMIM:248510), which when mutated leads to disease.
4	F43C1.1	F43C1.1	n/a	chrIII 4,213,606	contains similarity to Pfam domains PF00481 (Protein phosphatase 2C) , PF00560 (Leucine Rich Repeat) (11)contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR001611 (Leucine-rich repeat), IPR000694 (Proline-rich region), IPR003591 (Leucine-rich repeat, typical subtype), IPR014045 (Protein phosphatase 2C, N-terminal)
5	F52C6.13	F52C6.13	n/a	chrII 1,930,469
6	F13B6.2	F13B6.2	n/a	chrIV 7,459,793
7	T22F3.7	T22F3.7	n/a	chrV 3,599,159	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
8	wts-1	T20F10.1	n/a	chrI 10,294,898	C. elegans WTS-1 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00433 (Protein kinase C terminal domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
9	D1081.3	D1081.3	n/a	chrI 8,466,325	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
10	W03G1.3	W03G1.3	n/a	chrIV 512,107
11	twk-26	C33D12.3	n/a	chrX 3,052,381	C. elegans TWK-26 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
12	clk-2	C07H6.6	n/a	chrIII 7,516,797	The clk-2 gene encodes an ortholog of the S. cerevisiae telomere length-regulating protein Tel2p that has been shown to bind a number of DNA structures in vitro, including single-, double- and four-stranded DNA; in C. elegans, CLK-2 activity is required for the DNA damage and S phase replication checkpoints, for embryonic development, and for normal biological rhythms and life span; a functional CLK-2::GFP fusion protein is detected exclusively in the cytoplasm of somatic tissues.
13	W04C9.2	W04C9.2	n/a	chrI 489,263
14	C49A9.2	C49A9.2	n/a	chrIV 6,226,732	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
15	pxn-2	K09C8.5	n/a	chrX 10,975,651	C. elegans PXN-2 protein; contains similarity to Pfam domains PF00047 (Immunoglobulin domain) (2), PF00560 (Leucine Rich Repeat) (3), PF01462 (Leucine rich repeat N-terminal domain) , PF07679 (Immunoglobulin I-set domain) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR013098 (Immunoglobulin I-set), IPR010255 (Haem peroxidase), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR007110 (Immunoglobulin-like), IPR002007 (Haem peroxidase, animal), IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
16	fbxa-51	T12B5.1	n/a	chrIII 962,902	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
17	clec-21	T07H3.4	n/a	chrII 1,583,563	C. elegans CLEC-21 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
18	fbxb-39	M01D1.7	n/a	chrII 1,040,136	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
19	smg-5	W02D3.8	n/a	chrI 6,735,096	smg-5 encodes a novel protein that contains two N-terminal tetratricopeptide (TPR) repeats and a C-terminal PINc domain found in nucleotide-binding proteins; SMG-5 is a component of the nonsense-mediated mRNA decay (NMD) pathway and likely functions in regulation of dephosphorylation of SMG-2, the C. elegans UPF1 ortholog, an ATPase and RNA helicase required for NMD in worms, yeast, and mammals; SMG-5 physically interacts with SMG-7, SMG-2, and the PAA-1 and LET-92 structural and catalytic subunits, respectively, of a protein phosphatase 2A (PP2A), suggesting that SMG-5 may function to direct SMG-2 to a PP2A phosphatase that regulates its activity in vivo; SMG-5 also interacts, in vivo, with components of the RNA interference (RNAi) pathway, suggesting a potential link between RNAi and NMD; SMG-5::GFP fusion proteins localize to both the nucleus and the cytoplasm.
20	F19C7.2	F19C7.2	n/a	chrIV 4,601,343	contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
21	cul-6	K08E7.7	n/a	chrIV 12,588,438	cul-6 encodes a member of the cullin family that may physically interact with SKR-3.
22	F28C1.1	F28C1.1	n/a	chrV 12,452,041	contains similarity to Drosophila melanogaster Flybase gene name is CG6695-PA;; FLYBASE:CG6695
23	B0285.6	B0285.6	n/a	chrIII 4,354,080	B0285.6 encodes a predicted sodium-coupled carboxylate transporter that is one of four C. elegans proteins related to Drosophila Indy and the mammalian NaDC1 and NaDC3 transporters; B0285.6::lacZ reporter fusions are expressed in the excretory cell, from early larval stages through adulthood, with some later expression occasionally seen in two large unidentified structures on the dorsal side of the pharyngeal terminal bulb.
24	T11F9.1	T11F9.1	n/a	chrV 11,460,688	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
25	F17A2.3	F17A2.3	n/a	chrX 12,308,161	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
26	T20G5.10	T20G5.10	n/a	chrIII 10,211,438	contains similarity to Pfam domain PF06320 GCN5-like protein 1 (GCN5L1) contains similarity to Interpro domain IPR009395 (GCN5-like 1)
27	K10D11.3	K10D11.3	n/a	chrIV 12,984,093	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
28	F55C10.4	F55C10.4	n/a	chrV 11,387,665	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
29	C26D10.4	C26D10.4	n/a	chrII 8,331,544	contains similarity to Pfam domains PF08544 (GHMP kinases C terminal) , PF00288 (GHMP kinases N terminal domain) contains similarity to Interpro domains IPR006206 (Mevalonate and galactokinase), IPR001174 (Galactokinase/homoserine kinase), IPR006204 (GHMP kinase), IPR014721 (Ribosomal protein S5 domain 2-type fold), IPR013750 (GHMP kinase, C-terminal)
30	srw-32	K03D7.11	n/a	chrV 17,509,470	C. elegans SRW-32 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
31	pink-1	EEED8.9	n/a	chrII 5,394,469	pink-1 encodes a predicted serine/threonine protein kinase that is most similar to the Drosophila and human PINK1 (PTEN-induced kinase) protein kinases, the latter of which has been implicated in familial forms of Parkinson's disease; although loss of C. elegans pink-1 activity via large-scale RNAi screens results in no obvious abnormalities, studies in Drosophila indicate that Drosophila PINK1 is a mitochondrial protein that genetically interacts with Drosophila parkin and is essential for maintaining mitochondrial function and integrity in several tissues, including flight muscles and dopaminergic neurons.
32	fbxa-60	T12B5.10	n/a	chrIII 945,562	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
33	Y11D7A.8	Y11D7A.8	n/a	chrIV 9,252,608	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
34	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
35	srh-265	T06E6.9	n/a	chrV 15,416,909	C. elegans SRH-265 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
36	F49F1.7	F49F1.7	n/a	chrIV 4,124,635	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
37	F30A10.6	F30A10.6	n/a	chrI 9,490,547	contains similarity to Pfam domain PF02383 SacI homology domain contains similarity to Interpro domain IPR002013 (Synaptojanin, N-terminal)
38	srw-88	T06G6.7	n/a	chrI 12,721,084	C. elegans SRW-88 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
39	F23F12.8	F23F12.8	n/a	chrIII 6,485,986	F23F12.8 encodes a large (980-residue) protein, predicted to be secreted, with two chitin-binding peritrophin-A domains, separated by a low-complexity region; F23F12.8 is synthesized in larval and adult pharynx, a known site of chitin deposition; like CEJ-1 and CPG-2 in embryos, F23F12.8 might participate in chitin synthesis, and its peritrophin-A domains might enable mechanical cross-linking of chitin.
40	T05E12.3	T05E12.3	n/a	chrV 17,077,410	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
41	nfyc-1	F23F1.1	n/a	chrII 44,432	C. elegans NFYC-1 protein; contains similarity to Pfam domains PF00808 (Histone-like transcription factor (CBF/NF-Y) and archaeal histone) , PF00125 (Core histone H2A/H2B/H3/H4) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR007125 (Histone core), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
42	C18B10.6	C18B10.6	n/a	chrV 7,480,150	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
43	C16B8.2	C16B8.2	n/a	chrX 3,963,843
44	mrp-2	F57C12.4	n/a	chrX 568,214	mrp-2 encodes a predicted multidomain transmembrane protein that is a member of the ATP-binding cassette (ABC) superfamily of transport proteins and is homologous to the human multidrug resistance-associated protein 1 (MRP1, OMIM:158343); by homology, MRP-2 is predicted to function as a membrane pump that couples the energy of ATP hydrolysis to membrane transport; as loss of MRP-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of MRP-2 in C. elegans development and/or behavior is not yet known; mrp-2 expression is, however, upregulated early in the exit from the alternative dauer stage and then remains induced, suggesting that MRP-2 activity is required for the transition to, and maintenance of, a more active metabolic state.
45	R105.1	R105.1	n/a	chrIV 4,635,811	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
46	T15H9.2	T15H9.2	n/a	chrII 9,616,485	contains similarity to Homo sapiens Putative uncharacterized protein DKFZp686J1372; ENSEMBL:ENSP00000341653
47	ugt-49	AC3.2	n/a	chrV 10,373,259	C. elegans UGT-49 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
48	T05D4.3	T05D4.3	n/a	chrIII 13,568,545	contains similarity to Interpro domain IPR005838 (Type III secretion system inner membrane P protein)
49	T15B7.13	T15B7.13	n/a	chrV 6,827,999	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
50	F32B4.6	F32B4.6	n/a	chrI 11,516,108	contains similarity to Pfam domains PF07819 (PGAP1-like protein) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR012908 (PGAP1-like)