UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nlp-10	F37A8.4	2.9999999999999997e-64	chrIII 3,934,743	nlp-10 encodes four predicted neuropeptide-like proteins; nlp-10 is part of a GGxY neuropeptide family that has members in several other nematode species; nlp-10 is expressed in a variety of neurons, including ASK, ADL, CAN, two lateral neurons, two anterior pharyngeal neurons, one tail neuron, and one male tail neuron; as loss of nlp-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-10-encoded peptides in development and/or behavior is not yet known.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	C30B5.7	C30B5.7	n/a	chrII 6,225,999	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003944 (Protease-activated receptor 4)
4	aqp-5	C35A5.1	n/a	chrV 10,492,631	aqp-5 encodes a putative aquaporin with no known substrate, since AQP-5 expressed in Xenopus oocytes has no effect on water, glycerol, or urea permeability; AQP-5 also has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-6; AQP-5 is expressed in I1 and I2 pharyngeal interneurons, and is orthologous to human AQP8 (OMIM:603750).
5	F26A10.1	F26A10.1	n/a	chrX 7,627,709
6	C13A2.7	C13A2.7	n/a	chrV 7,266,655
7	C37C3.10	C37C3.10	n/a	chrV 7,862,685
8	T05E11.8	T05E11.8	n/a	chrIV 11,105,287	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
9	T27F2.4	T27F2.4	n/a	chrV 11,650,405	contains similarity to Interpro domain IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
10	C02B8.7	C02B8.7	n/a	chrX 8,137,743
11	M03E7.1	M03E7.1	n/a	chrV 5,624,123	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
12	C44H9.8	C44H9.8	n/a	chrV 12,847,707	contains similarity to Bacillus anthracis Sensory box histidine kinase PhoR.; TR:Q81L02
13	ZC412.1	ZC412.1	n/a	chrV 14,855,683	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
14	C50A2.3	C50A2.3	n/a	chrIV 1,148,209
15	sri-13	M01G12.13	n/a	chrI 12,141,648	C. elegans SRI-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	flp-6	F07D3.2	n/a	chrV 9,472,810	C. elegans FLP-6 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
17	C50F4.9	C50F4.9	n/a	chrV 9,523,727	contains similarity to Streptococcus agalactiae Hypothetical protein.; TR:Q8E2N5
18	cpx-2	K03A11.2	n/a	chrX 13,067,761	C. elegans CPX-2 protein; contains similarity to Pfam domain PF05835 Synaphin protein contains similarity to Interpro domain IPR008849 (Synaphin)
19	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
20	M03A1.3	M03A1.3	n/a	chrII 4,558,668	M03A1.3 encodes a protein with ~10 predicted transmembrane sequences; it has an internal repeat (in residues 74-351 and 377-668), with some similarity in these repeated domains to worm C05D12.1 and C13B4.1, and to mammalian stromal cell derived factor receptor 2.
21	F47B8.3	F47B8.3	n/a	chrV 14,322,155	contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR012336 (Thioredoxin-like fold)
22	F40G9.8	F40G9.8	n/a	chrIII 164,235
23	gst-2	K08F4.6	n/a	chrIV 10,140,892	C. elegans GST-2 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
24	K09H11.6	K09H11.6	n/a	chrV 5,735,411
25	C18A11.2	C18A11.2	n/a	chrX 8,067,797
26	W05B10.4	W05B10.4	n/a	chrV 12,668,893	contains similarity to Pfam domain PF00788 Ras association (RalGDS/AF-6) domain contains similarity to Interpro domain IPR000159 (Ras-association)
27	F11A5.13	F11A5.13	n/a	chrV 16,226,353	contains similarity to Clostridium acetobutylicum MDR-type permease.; TR:Q97D15
28	F47F2.3	F47F2.3	n/a	chrX 3,894,817	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
29	nhr-206	R07B7.13	n/a	chrV 12,092,930	C. elegans NHR-206 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
31	F23F1.7	F23F1.7	n/a	chrII 39,046	contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
32	ZK816.1	ZK816.1	n/a	chrX 3,359,733
33	str-45	T09F5.3	n/a	chrV 15,159,744	C. elegans STR-45 protein ; contains similarity to Homo sapiens 42 kDa protein; VG:OTTHUMP00000169906
34	C18H7.9	C18H7.9	n/a	chrIV 603,317	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
35	M03E7.4	M03E7.4	n/a	chrV 5,611,266	M03E7.4 encodes a protein, predicted to be secreted, with one chitin-binding peritrophin-A and three low-density lipoprotein receptor domain class A domains; M03E7.4 has no obvious function in mass RNAi assays.
36	F49C12.10	F49C12.10	n/a	chrIV 9,318,735	contains similarity to Pfam domain PF08241 Methyltransferase domain contains similarity to Interpro domain IPR013216 (Methyltransferase type 11)
37	T22B2.2	T22B2.2	n/a	chrX 3,922,438
38	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
39	glb-15	F35B12.8	n/a	chrV 11,617,517	glb-15 encodes a globin with no obvious function in mass RNAi assays.
40	B0546.3	B0546.3	n/a	chrIV 3,380,351	contains similarity to Pfam domain PF03226 Yippee putative zinc-binding protein contains similarity to Interpro domain IPR004910 (Yippee-like protein)
41	ins-3	ZK75.3	n/a	chrII 5,990,388	ins-3 encodes one of several insulin-related peptides; INS-3 is classified as a Type-beta insulin based on the predicted arrangement of disulfide bonds; gfp gene fusions with the promoter and enhancer regions indicate that INS-3 is expressed in some amphid sensory neurons.
42	F54B8.4	F54B8.4	n/a	chrV 15,816,808	The F54B8.4 gene encodes a homolog of Death Associated Protein 1 (DAP-1) protein that may be involved in apoptosis.
43	srx-43	T10C6.3	n/a	chrV 16,018,889	C. elegans SRX-43 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
44	str-253	F41B5.8	n/a	chrV 2,253,703	C. elegans STR-253 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
45	str-115	F07B10.3	n/a	chrV 11,269,735	C. elegans STR-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	srh-251	R08H2.4	n/a	chrV 15,379,118	C. elegans SRH-251 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	C24D10.8	C24D10.8	n/a	chrIV 5,165,608	n/a
48	B0546.5	B0546.5	n/a	chrIV 3,389,078	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domain IPR010601 (Protein of unknown function DUF1182)
49	srg-34	Y51A2D.12	n/a	chrV 18,563,515	C. elegans SRG-34 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
50	str-47	F07C4.1	n/a	chrV 7,646,392	C. elegans STR-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)