UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F26H9.5	F26H9.5	0	chrI 9,313,557	contains similarity to Pfam domain PF00266 Aminotransferase class-V contains similarity to Interpro domains IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR003248 (Phosphoserine aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
2	F28A10.10	F28A10.10	n/a	chrII 831,531	contains similarity to Pfam domain PF01467 Cytidylyltransferase contains similarity to Interpro domains IPR004821 (Cytidyltransferase-related), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004820 (Cytidylyltransferase)
3	C35A11.4	C35A11.4	n/a	chrV 5,391,300	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
4	mif-2	C52E4.2	n/a	chrV 11,977,505	C. elegans MIF-2 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)
5	T07A9.10	T07A9.10	n/a	chrIV 391,835	contains similarity to Pfam domain PF00995 Sec1 family contains similarity to Interpro domain IPR001619 (Sec1-like protein)
6	F39B2.3	F39B2.3	n/a	chrI 14,788,812	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
7	oxi-1	Y39A1C.2	n/a	chrIII 10,862,495	C. elegans OXI-1 protein; contains similarity to Pfam domain PF00632 HECT-domain (ubiquitin-transferase) contains similarity to Interpro domain IPR000569 (HECT)
8	F25E5.1	F25E5.1	n/a	chrV 7,468,526	contains similarity to Interpro domain IPR009091 (Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)
9	mrp-3	E03G2.2	n/a	chrX 15,934,560	C. elegans MRP-3 protein; contains similarity to Pfam domains PF00664 (ABC transporter transmembrane region) (2), PF00005 (ABC transporter) (2)contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR001140 (ABC transporter, transmembrane region), IPR003593 (AAA+ ATPase, core)
10	ppk-3	VF11C1L.1	n/a	chrX 12,972,222	C. elegans PPK-3 protein; contains similarity to Pfam domains PF01504 (Phosphatidylinositol-4-phosphate 5-Kinase) , PF01363 (FYVE zinc finger) contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002498 (Phosphatidylinositol-4-phosphate 5-kinase, core), IPR016034 (Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup), IPR002423 (Chaperonin Cpn60/TCP-1), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
11	F21G4.1	F21G4.1	n/a	chrX 9,890,917	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR004156 (Organic anion transporter polypeptide OATP), IPR000539 (Frizzled protein), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
12	gly-13	B0416.6	n/a	chrX 9,295,081	gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates; gly-13 is expressed throughout development in many cell types; gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14.
13	F15D4.5	F15D4.5	n/a	chrII 13,246,445	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
14	W04B5.1	W04B5.1	n/a	chrIII 2,428,781
15	C06B8.7	C06B8.7	n/a	chrV 15,505,052	contains similarity to Pfam domain PF00530 Scavenger receptor cysteine-rich domain contains similarity to Interpro domains IPR002160 (Proteinase inhibitor I3, Kunitz legume), IPR001190 (Speract/scavenger receptor), IPR011050 (Pectin lyase fold/virulence factor), IPR006626 (Parallel beta-helix repeat), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR017448 (Speract/scavenger receptor related)
16	C34B2.8	C34B2.8	n/a	chrI 10,686,429	contains similarity to Pfam domain PF06212 GRIM-19 protein contains similarity to Interpro domain IPR009346 (GRIM-19)
17	elo-3	D2024.3	n/a	chrIV 7,238,796	The elo-3 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-3 may be required for normally rapid growth.
18	R03A10.3	R03A10.3	n/a	chrX 15,438,160	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR011037 (Pyruvate kinase, beta-barrel-like), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
19	his-3	T10C6.12	n/a	chrV 16,040,965	his-3 encodes an H2A histone; by homology, HIS-3 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-3 is a replication-dependent histone locus that resides in the HIS1 cluster on chromosome V.
20	ZK180.4	ZK180.4	n/a	chrIV 4,512,601	contains similarity to Pfam domains PF00025 (ADP-ribosylation factor family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR006687 (GTP-binding protein SAR1), IPR013684 (Miro-like), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR006688 (ADP-ribosylation factor), IPR006689 (ARF/SAR superfamily)
21	B0019.2	B0019.2	n/a	chrI 12,777,941	contains similarity to Pfam domains PF04435 (Domain of unknown function (DUF545)) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR006570 (SPK), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR009057 (Homeodomain-like)
22	ptr-23	ZK270.1	n/a	chrI 14,911,168	ptr-23 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-23 is strongly required for normal molting from L4 to adult stages (a role conserved in C. briggsae); PTR-23 is also required for normal male tail development, vulval morphogenesis, adult alae formation, and (partly) for endocytosis of yolk by oocytes.
23	dog-1	F33H2.1	n/a	chrI 15,020,116	dog-1 encodes a predicted DEAH helicase, orthologous to the human BRCA1-binding protein BACH1 (OMIM:605882, mutated in early-onset breast cancer); DOG-1 is required for maintenance of polyguanine tracts of germline and somatic DNA, and is proposed to resolve the secondary structure that can occur in guanine-rich DNA during lagging-strand DNA synthesis.
24	F08A8.3	F08A8.3	n/a	chrI 12,948,957	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
25	T14B4.1	T14B4.1	n/a	chrII 6,739,132
26	C25H3.4	C25H3.4	n/a	chrII 5,692,793	contains similarity to Pfam domains PF01472 (PUA domain) , PF01253 (Translation initiation factor SUI1) contains similarity to Interpro domains IPR004521 (Uncharacterized domain 2), IPR015947 (PUA-like), IPR001950 (Translation initiation factor SUI1), IPR002478 (PUA)
27	clec-26	T20B3.12	n/a	chrV 16,849,392	C. elegans CLEC-26 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	T24C12.3	T24C12.3	n/a	chrX 2,200,203	contains similarity to Pfam domains PF00294 (pfkB family carbohydrate kinase) , PF04227 (Indigoidine synthase A like protein) contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR002139 (Ribokinase), IPR007342 (Indigoidine synthase A like protein), IPR002173 (Carbohydrate/puine kinase, PfkB, conserved site)
29	C11D2.3	C11D2.3	n/a	chrIV 6,154,348
30	sec-8	Y106G6H.7	n/a	chrI 10,449,365	The sec-8 gene encodes an ortholog of SEC8 in S. cerevisiae, a component of the exocyst complex required genetically for endocytosis, for normal cellular morphology in the intestine, and for growth at normal rates during development.
31	smg-5	W02D3.8	n/a	chrI 6,735,096	smg-5 encodes a novel protein that contains two N-terminal tetratricopeptide (TPR) repeats and a C-terminal PINc domain found in nucleotide-binding proteins; SMG-5 is a component of the nonsense-mediated mRNA decay (NMD) pathway and likely functions in regulation of dephosphorylation of SMG-2, the C. elegans UPF1 ortholog, an ATPase and RNA helicase required for NMD in worms, yeast, and mammals; SMG-5 physically interacts with SMG-7, SMG-2, and the PAA-1 and LET-92 structural and catalytic subunits, respectively, of a protein phosphatase 2A (PP2A), suggesting that SMG-5 may function to direct SMG-2 to a PP2A phosphatase that regulates its activity in vivo; SMG-5 also interacts, in vivo, with components of the RNA interference (RNAi) pathway, suggesting a potential link between RNAi and NMD; SMG-5::GFP fusion proteins localize to both the nucleus and the cytoplasm.
32	vpr-1	F33D11.11	n/a	chrI 5,869,119	C. elegans VPR-1 protein; contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein), IPR016763 (Vesicle-associated membrane protein)
33	Y48A6C.4	Y48A6C.4	n/a	chrIII 11,121,345	Y48A6C.4 encodes an ortholog of S. cerevisiae IPI1 that may suppress tumorous growth in the germline; like PRO-1, -2, and -3, Y48A6C.4 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline.
34	C56G3.2	C56G3.2	n/a	chrX 7,365,880	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
35	F56D1.2	F56D1.2	n/a	chrII 5,476,416	contains similarity to Pfam domain PF08357 SEFIR domain contains similarity to Interpro domain IPR013568 (SEFIR)
36	prx-19	F54F2.8	n/a	chrIII 8,808,467	prx-19 is orthologous to the human gene PEROXISOMAL FARNESYLATED PROTEIN (PXF; OMIM:600279), which when mutated leads to peroxisome biogenesis (Zellweger) syndrome of complementation group J.
37	R04E5.2	R04E5.2	n/a	chrX 8,814,421	R04E5.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, M02F4.3, and R13G10.4; by orthology with MAM3, R04E5.2 may participate in metal homoeostasis; R04E5.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; R04E5.2 has no obvious function in RNAi assays.
38	ZK1251.9	ZK1251.9	n/a	chrIV 9,701,830	contains similarity to Pfam domain PF08513 LisH contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR006594 (LisH dimerisation motif), IPR013720 (LisH dimerisation motif, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR016024 (Armadillo-type fold)
39	C06E1.3	C06E1.3	n/a	chrIII 8,582,414	contains similarity to Drosophila melanogaster Flybase gene name is mol-PD;; FLYBASE:CG4482
40	F55G1.9	F55G1.9	n/a	chrIV 7,476,741	contains similarity to Pfam domain PF03807 NADP oxidoreductase coenzyme F420-dependent contains similarity to Interpro domains IPR004455 (NADP oxidoreductase, coenzyme F420-dependent), IPR000304 (Delta 1-pyrroline-5-carboxylate reductase), IPR016040 (NAD(P)-binding)
41	6R55.2	6R55.2	n/a	chrX 17,713,765
42	gly-3	ZK688.8	n/a	chrIII 7,916,183	gly-3 encodes an N-acetylgalactosaminyltransferase that is functional in vitro.
43	glrx-5	Y49E10.2	n/a	chrIII 12,373,098	C. elegans GLRX-5 protein; contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR014025 (Glutaredoxin subgroup), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004480 (Glutaredoxin-related protein)
44	cogc-8	R02D3.2	n/a	chrIV 242,340	cogc-8 encodes an ortholog of mammalian COG-8, a subunit of lobe B of the conserved oligomeric Golgi complex (COGC); COGC-8 is weakly required for normal gonadal distal tip cell migration, a process that also requires seven other orthologs of COGC subunits; like other lobe B subunits in both C. elegans and S. cerevisiae, COGC-8 is only partially required for normal function, while lobe A subunits are strongly required in either worms or yeast.
45	F31E3.4	F31E3.4	n/a	chrIII 6,965,804	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR011046 (WD40 repeat-like), IPR006055 (Exonuclease), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
46	C08B6.2	C08B6.2	n/a	chrV 10,106,583	contains similarity to Rattus norvegicus Adenomatous polyposis coli protein (APC protein).; SW:APC_RAT
47	sec-10	C33H5.9	n/a	chrIV 7,780,928	C. elegans SEC-10 protein; contains similarity to Pfam domain PF07393 Exocyst complex component Sec10 contains similarity to Interpro domain IPR009976 (Exocyst complex component Sec10)
48	C03B1.7	C03B1.7	n/a	chrX 6,343,858	contains similarity to Sulfolobus tokodaii DNA double-strand break repair rad50 ATPase.; SW:Q96YR5
49	syn-16	ZC155.7	n/a	chrIII 5,208,372	C. elegans SYN-16 protein; contains similarity to Pfam domains PF00804 (Syntaxin) , PF05739 (SNARE domain) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region)
50	C02G6.1	C02G6.1	n/a	chrV 5,878,092	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)