UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	dsl-4	F16B12.2	1.9999999999999999e-168	chrX 14,091,441	dsl-4 encodes a putative secreted protein with a single DSL domain and three EGF domains in series, somewhat like Delta/LAG-2; unlike the nematode-specific family of Delta/LAG-2-like proteins (including DSL-1, -2, -3, -5, -6, and -7), DSL-4 is evolutionarily divergent, with perhaps a distant affinity to APX-1, ARG-1, and LAG-2.
2	twk-10	K04A8.4	n/a	chrV 6,553,200	C. elegans TWK-10 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
3	T02B11.6	T02B11.6	n/a	chrV 887,079	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
4	acr-5	K03F8.2	n/a	chrIII 6,512,172	acr-5 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors that is expressed in the nervous system.
5	C07A9.12	C07A9.12	n/a	chrIII 9,726,313	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
6	F56H6.9	F56H6.9	n/a	chrI 12,305,199	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
7	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	col-78	W07A12.5	n/a	chrII 9,153,340	C. elegans COL-78 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
9	F01F1.14	F01F1.14	n/a	chrIII 5,882,603
10	T18D3.7	T18D3.7	n/a	chrX 12,442,974	contains similarity to Pfam domain PF01166 TSC-22/dip/bun family contains similarity to Interpro domain IPR000580 (TSC-22 / Dip / Bun)
11	tsg-101	C09G12.9	n/a	chrIV 3,512,510	C09G12.9 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps23p and human TUMOR SUSCEPTIBILITY GENE 101 (TSG101; OMIM:601387), mutations in which are associated with several types of cancer and with varying responses to HIV infection; the product of C09G12.9 is predicted to be a component of C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport), and RNAi experiments indicate that its activity is essential for embryonic and larval development.
12	srbc-52	F54B8.10	n/a	chrV 15,828,326	C. elegans SRBC-52 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
13	math-2	C08F1.1	n/a	chrII 1,799,617	C. elegans MATH-2 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
14	sma-3	R13F6.9	n/a	chrIII 6,862,404	sma-3 encodes a Smad protein; during development, SMA-3 functions as part of a DBL-1/SMA-6 TGF-beta-related signaling pathway that controls body size and male tail sensory ray and spicule formation; sma-3 is widely expressed at all developmental stages, beginning during embryogenesis, continuing through all larval stages, and seen very strongly in adult hermaphrodites and males; a SMA-3::GFP is detected in the pharynx, intestine, and hypodermis and localizes to the nucleus; sma-3 expression in the hypodermis is necessary and sufficient for normal body size; SMA-3 can physically interact with the LIN-31 forkhead transcription factor.
15	srx-34	T01C4.4	n/a	chrV 7,119,646	C. elegans SRX-34 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
16	uev-3	F26H9.7	n/a	chrI 9,311,457	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
17	F55G7.3	F55G7.3	n/a	chrX 11,941,116	contains similarity to Saccharomyces cerevisiae appears to control expression of spliceosome components PRP4 and PRP3; SGD:YDR464W
18	F26H9.2	F26H9.2	n/a	chrI 9,292,112	contains similarity to Pfam domain PF02755 RPEL repeat contains similarity to Interpro domain IPR004018 (RPEL repeat)
19	lrp-2	T21E3.3	0.000000000000002	chrI 3,939,445	C. elegans LRP-2 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (6), PF07974 (EGF-like domain) , PF00057 (Low-density lipoprotein receptor domain class A) (14), PF00058 (Low-density lipoprotein receptor repeat class B) (7)contains similarity to Interpro domains IPR000033 (), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR015943 (WD40/YVTN repeat-like)
20	srsx-1	F40D4.5	n/a	chrV 17,177,360	C. elegans SRSX-1 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
21	F07H5.7	F07H5.7	n/a	chrII 8,793,642
22	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
23	F47F2.2	F47F2.2	n/a	chrX 3,886,480
24	C04E6.3	C04E6.3	n/a	chrV 5,920,241
25	F55G1.12	F55G1.12	n/a	chrIV 7,494,554	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
26	exc-9	F20D12.5	n/a	chrIV 7,940,302	exc-9 encodes a LIM domain-containing protein; exc-9 activity is required for proper development and morphogenesis of the excretory cell canal.
27	str-225	C07G3.6	n/a	chrV 3,508,534	C. elegans STR-225 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001307 (Thiosulphate sulphurtransferase, conserved site)
28	ZK112.6	ZK112.6	n/a	chrIII 7,740,126	contains similarity to Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-sactivating enzyme).; SW:Q72LY9
29	srbc-81	Y45G12C.8	n/a	chrV 2,523,361	C. elegans SRBC-81 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR002229 (Blood group Rhesus C/E and D polypeptide)
30	xbx-1	F02D8.3	n/a	chrV 14,981,466	C. elegans XBX-1 protein ; contains similarity to Homo sapiens Isoform 1 of Cytoplasmic dynein 2 light intermediate chain 1; ENSEMBL:ENSP00000260605
31	K09H9.4	K09H9.4	n/a	chrI 3,134,515	contains similarity to Interpro domains IPR015706 (RNA-directed DNA polymerase (reverse transcriptase), related), IPR003286 (Nematode reverse transcriptase-like)
32	srw-122	H27D07.5	n/a	chrV 2,951,456	C. elegans SRW-122 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
33	str-136	F21F8.9	n/a	chrV 8,278,202	C. elegans STR-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
34	C39D10.1	C39D10.1	n/a	chrX 7,906,986
35	R09H3.1	R09H3.1	n/a	chrX 1,660,650	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
36	nhr-233	Y32B12B.6	n/a	chrV 16,570,335	C. elegans NHR-233 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
37	T06H11.2	T06H11.2	n/a	chrX 10,129,860	contains similarity to Sulfolobus tokodaii Putative reverse gyrase.; TR:Q975P6
38	str-200	F20E11.4	n/a	chrV 17,457,362	C. elegans STR-200 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	F55E10.5	F55E10.5	n/a	chrX 8,335,538
40	fbxa-112	Y102A5C.13	n/a	chrV 16,947,523	C. elegans FBXA-112 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
41	srd-56	E04F6.14	n/a	chrII 7,202,553	C. elegans SRD-56 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	F55H12.3	F55H12.3	0.0000000000002	chrI 8,884,703	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF07645 (Calcium binding EGF domain) , PF07699 (GCC2 and GCC3) (3), PF07974 (EGF-like domain) (5), PF00057 (Low-density lipoprotein receptor domain class A) , PF02494 (HYR domain) , PF00084 (Sushi domain (SCR repeat)) (2)contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR011641 (GCC2 and GCC3), IPR016187 (C-type lectin fold), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding), IPR008985 (Concanavalin A-like lectin/glucanase)
43	C44B12.6	C44B12.6	n/a	chrIV 1,131,250	contains similarity to Interpro domain IPR010345 (Interleukin-17)
44	nlp-13	E03D2.1	n/a	chrV 4,237,211	nlp-13 encodes a predicted neuropeptide of the MSFamide family; expressed primarily in neurons or in the endocrine/secretory cells, and expression includes pharyngeal neurons that modulate pharyngeal pumping of food.
45	srab-1	C04F5.4	n/a	chrV 5,101,092	C. elegans SRAB-1 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
46	C24A3.1	C24A3.1	n/a	chrX 9,003,584	contains similarity to Aedes aegypti Condensin, SMC5-subunit, putative (Fragment).; TR:Q16IF0
47	F59D12.1	F59D12.1	n/a	chrX 15,669,484	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
48	srt-9	C50H11.5	n/a	chrV 3,078,685	C. elegans SRT-9 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	EGAP2.2	EGAP2.2	n/a	chrII 5,230,269
50	abf-3	F54B8.5	n/a	chrV 15,817,602	abf-3 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-3 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.