UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F14H3.6	F14H3.6	4e-124	chrV 16,058,082	contains similarity to Homo sapiens Similar to golgi SNAP receptor complex member 2; ENSEMBL:ENSP00000318814
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	nos-2	ZK1127.1	n/a	chrII 7,066,218	nos-2 encodes one of three genes in C. elegans that contains a putative zinc-binding domain similar to the one found in Drosophila nanos; nos-2 affects incorporation of primordial germ cells into the somatic gonad, is required redundantly with nos-1 to prevent primordial germ cells from dividing in starved animals and to maintain germ cell viability during larval development in hermaphrodites and in males, and also functions together with nos-1 and nos-3 in the hermaphrodite switch from spermatogenesis to oogenesis; nos-2 is expressed in the primordial germ cells around the time of gastrulation from a maternal RNA associated with P granules, and it is expressed coordinately with nos-1in a dynamic fashion until the embryonic 200-cell stage.
4	mom-2	F38E1.7	n/a	chrV 8,357,065	mom-2 encodes a member of the Wnt family of secreted signaling glycoproteins that is required for induction of endodermal (gut) tissue in the 4-cell stage embryo; MOM-2, required in the inducing blastomere (P2) at the 4-cell stage, may be the ligand for MOM-5, a Frizzled homolog, thought to act in the receiving blastomere (EMS); MOM-2 genetically interacts in the same pathway as KIN-19, but parallel to APR-1; MOM-2 also may be a ligand for LIN-18, a Ryk homolog.
5	F08F3.6	F08F3.6	n/a	chrV 5,419,025	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	W02F12.3	W02F12.3	n/a	chrV 6,703,798	contains similarity to Leishmania braziliensis Proteophosphoglycan ppg4.; TR:A4HM87
7	R04D3.4	R04D3.4	n/a	chrX 13,288,277	contains similarity to Rattus norvegicus Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkessdisease-associated protein homolog).; SW:AT7A_RAT
8	F14D7.2	F14D7.2	n/a	chrV 14,292,817	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
9	K04C1.5	K04C1.5	n/a	chrX 14,248,813	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
10	rgs-8.1	F52D2.2	n/a	chrX 1,953,014	C. elegans RGS-8.1 protein; contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
11	T05F1.2	T05F1.2	n/a	chrI 9,623,710	T05F1.2 encodes a novel protein; in situ hybridization studies indicate that T05F1.2 mRNA is expressed in the medial germline.
12	H04M03.3	H04M03.3	n/a	chrIV 5,892,434	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
13	ZK829.9	ZK829.9	n/a	chrIV 11,971,563	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
14	fbxa-215	Y45F10C.3	n/a	chrIV 13,666,087	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
15	T12G3.6	T12G3.6	n/a	chrIV 12,030,485	contains similarity to Helicobacter pylori Hypothetical protein HP1128.; TR:O25753
16	R04D3.2	R04D3.2	n/a	chrX 13,285,808	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6
17	F32D1.7	F32D1.7	n/a	chrV 4,375,562	contains similarity to Interpro domain IPR005405 (Potassium channel, voltage dependent, Kv3.4)
18	sdz-27	R07H5.4	n/a	chrIV 11,187,603	C. elegans SDZ-27 protein
19	F54D10.5	F54D10.5	n/a	chrII 3,807,652
20	F43G6.10	F43G6.10	n/a	chrII 11,809,738	contains similarity to Interpro domain IPR000694 (Proline-rich region)
21	F54D10.7	F54D10.7	n/a	chrII 3,820,711	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
22	F57C2.4	F57C2.4	n/a	chrII 14,525,575	contains similarity to Homo sapiens Crumbs protein homolog 1 precursor; ENSEMBL:ENSP00000256772
23	rgs-9	ZC53.7	n/a	chrX 1,916,166	C. elegans RGS-9 protein; contains similarity to Interpro domains IPR015905 (Isoleucyl-tRNA synthetase, class Ia, N-terminal), IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
24	Y75B12B.1	Y75B12B.1	n/a	chrV 15,185,232	Y75B12B.1 encodes a probable transposase, with many C. elegans paralogs and distant similarity to rotifer and insect transposases; Y75B12B.1 has no known function in mass RNAi assays; Y75B12B.1 mRNA is stabilized by bound GLD-1.
25	E02H4.6	E02H4.6	n/a	chrX 14,251,350	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
26	C37C3.9	C37C3.9	n/a	chrV 7,853,081	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
27	tbh-1	H13N06.6	n/a	chrX 15,501,790	tbh-1 encodes a putative dopamine beta-hydroxylate orthologous to human DBH (OMIM:609312, mutated in dopamine beta-hydroxylase deficiency).
28	C30F12.4	C30F12.4	n/a	chrI 6,972,971	contains similarity to Triticum aestivum Gamma-gliadin precursor.; SW:P08453
29	C17E4.3	C17E4.3	n/a	chrI 9,417,878	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
30	rmd-1	T05G5.7	n/a	chrIII 9,759,548	C. elegans RMD-1 protein; contains similarity to Interpro domain IPR011990 (Tetratricopeptide-like helical)
31	cpg-2	B0280.5	n/a	chrIII 7,102,966	cpg-2 encodes a protein with six chitin-binding peritrophin-A domains and three mucin-like regions; CPG-2 is individually dispensable for normal embryonic development; however, CPG-2 and CPG-1 are jointly required for osmotic integrity of early embryos, error-free chromosomal segregation during meiosis, polar body extrusion, association of the sperm pronucleus/centrosome complex (SPCC) with the early embryonic cortex, localization of PAR-2 in early embryos, posterior localization of P granules or PIE-1, and pseudocleavage; CPG-2, like CPG-1, is covalently linked to chondroitin, which itself is required for vulval morphogenesis, polar-body extrusion, and separation of the eggshell from the embryonic plasma membrane; cpg-2 mRNA, like that of cpg-1, is expressed specifically in the adult hermaphrodite germ line and is bound by GLD-1; CPG-2 has 34 potential chondroitin attachment sites, four of them verified by mass spectrometry, and transgenic CPG-2 synthesized in mammalian cells carries chondroitin sulfate chains; CPG-2's multiple peritrophin-A domains may enable mechanical cross-linking of chitin.
32	T21C9.13	T21C9.13	n/a	chrV 10,597,963	contains similarity to Fusobacterium nucleatum Branched chain amino acid transport system II carrier protein.; TR:Q8REN9
33	C17E7.4	C17E7.4	n/a	chrV 3,893,699
34	C53B7.2	C53B7.2	n/a	chrX 6,846,844	C53B7.2 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C53B7.2 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C53B7.2 has no obvious function in mass RNAi assays.
35	Y62H9A.6	Y62H9A.6	n/a	chrX 11,883,508	contains similarity to Brucella melitensis Hypothetical cytosolic protein BMEI0237.; TR:Q8YJ49
36	gln-6	C28D4.3	n/a	chrIV 9,740,184	C. elegans GLN-6 protein; contains similarity to Pfam domains PF03951 (Glutamine synthetase, beta-Grasp domain) , PF00120 (Glutamine synthetase, catalytic domain) contains similarity to Interpro domains IPR008147 (Glutamine synthetase, beta-Grasp), IPR014746 (Glutamine synthetase/guanido kinase, catalytic region), IPR008146 (Glutamine synthetase, catalytic region)
37	W05F2.3	W05F2.3	n/a	chrI 3,368,102
38	mex-6	AH6.5	n/a	chrII 9,525,192	mex-6 encodes a CCCH zinc-finger protein highly similar to MEX-5 that functions with MEX-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish PIE-1, MEX-1, and POS-1 asymmetry in embryos, and also affects formation of intestinal cells; MEX-6 and MEX-5 may act downstream of the PAR proteins.
39	clec-222	C03E10.6	n/a	chrV 11,271,884	C. elegans CLEC-222 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
40	B0393.3	B0393.3	n/a	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
41	msh-4	T02G5.6	n/a	chrII 7,078,297	C. elegans MSH-4 protein; contains similarity to Pfam domain PF00488 MutS domain V contains similarity to Interpro domain IPR000432 (DNA mismatch repair protein MutS, C-terminal)
42	C17G1.2	C17G1.2	n/a	chrX 9,922,096	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IJE7
43	C14B1.2	C14B1.2	n/a	chrIII 3,702,706	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81T15
44	F17E9.4	F17E9.4	n/a	chrIV 8,348,753
45	gln-5	F26D10.10	n/a	chrIV 17,272,909	C. elegans GLN-5 protein; contains similarity to Pfam domains PF03951 (Glutamine synthetase, beta-Grasp domain) , PF00120 (Glutamine synthetase, catalytic domain) contains similarity to Interpro domains IPR008147 (Glutamine synthetase, beta-Grasp), IPR014746 (Glutamine synthetase/guanido kinase, catalytic region), IPR008146 (Glutamine synthetase, catalytic region)
46	Y37D8A.19	Y37D8A.19	n/a	chrIII 12,930,534	contains similarity to Hordeum vulgare Nonspecific lipid-transfer protein 4.3 precursor (LTP 4.3).; SW:NL43_HORVU
47	pzf-1	T05G11.1	n/a	chrV 15,927,495	C. elegans PZF-1 protein; contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
48	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
49	F53F8.3	F53F8.3	n/a	chrV 20,684,555	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
50	C04B4.2	C04B4.2	n/a	chrX 12,284,223	contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)