UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F13D12.3	F13D12.3	1e-36	chrII 11,721,323	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
2	C10G11.1	C10G11.1	n/a	chrI 6,307,930
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	nlp-2	T24D8.5	n/a	chrX 2,344,350	C. elegans NLP-2 protein ;
5	F45E1.4	F45E1.4	n/a	chrX 7,986,049
6	gst-22	F21H7.1	n/a	chrV 16,231,635	C. elegans GST-22 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
7	Y51A2B.1	Y51A2B.1	n/a	chrV 18,373,264	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR016160 (Aldehyde dehydrogenase, conserved site)
8	C08E8.4	C08E8.4	n/a	chrV 18,372,276	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
9	ins-4	ZK75.1	n/a	chrII 5,996,546	ins-4 encodes an insulin-like peptide.
10	far-3	F15B9.1	n/a	chrV 12,997,151	C. elegans FAR-3 protein; contains similarity to Pfam domain PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) contains similarity to Interpro domain IPR008632 (Nematode fatty acid retinoid binding)
11	F20B6.6	F20B6.6	n/a	chrX 4,201,908	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
12	hgo-1	W06D4.1	n/a	chrI 9,052,445	hgo-1 encodes a putative homogentisate 1,2-dioxygenase, orthologous to human HGD (OMIM:607474, mutated in alkaptonuria), that is required for normal resistance to hypertonic stress; HGO-1 is expressed in larval and adult hypodermis and intestine, and in larval pharynx; HGO-1 is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
13	F20A1.10	F20A1.10	n/a	chrV 7,052,940
14	Y42A5A.3	Y42A5A.3	n/a	chrV 11,095,685	contains similarity to Bacillus subtilis Hypothetical protein yhen.; TR:O07596
15	C17H12.8	C17H12.8	n/a	chrIV 6,819,608	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
16	C07A9.8	C07A9.8	n/a	chrIII 9,688,522	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
17	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
18	clc-1	C09F12.1	n/a	chrX 11,048,302	clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes; clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva; in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions.
19	W02D9.10	W02D9.10	n/a	chrI 12,551,930
20	C35A5.4	C35A5.4	n/a	chrV 10,498,176	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000694 (Proline-rich region), IPR000535 (Major sperm protein)
21	tag-329	C50F4.3	n/a	chrV 9,535,638	C. elegans TAG-329 protein; contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
22	F21C10.4	F21C10.4	n/a	chrV 9,127,111	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
23	C07A12.2	C07A12.2	n/a	chrX 4,545,119
24	T28H10.3	T28H10.3	n/a	chrV 12,513,961	contains similarity to Pfam domain PF01650 Peptidase C13 family contains similarity to Interpro domain IPR001096 (Peptidase C13, legumain)
25	F15E6.4	F15E6.4	n/a	chrIV 4,291,666
26	srw-72	F20E11.6	n/a	chrV 17,467,788	C. elegans SRW-72 protein ;
27	tag-225	K07C11.5	n/a	chrV 8,202,146	K07C11.5 is orthologous to the human gene SIMILAR TO TISSUE INHIBITOR OF METALLOPROTEINASE 3 (SORSBY FUNDUS DYSTROPHY, PSEUDOINFLAMMATORY) (TIMP3; OMIM:188826), which when mutated leads to disease.
28	C42D4.1	C42D4.1	n/a	chrIV 7,189,738	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domains IPR002395 (HMW kininogen), IPR003677 (Protein of unknown function DUF148)
29	F35E2.3	F35E2.3	n/a	chrI 11,735,172	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
30	btb-21	F47C10.2	n/a	chrV 3,850,930	C. elegans BTB-21 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
31	ZK688.4	ZK688.4	n/a	chrIII 7,895,076
32	srx-20	R13H7.1	n/a	chrIV 6,868,598	C. elegans SRX-20 protein ;
33	F57H12.4	F57H12.4	n/a	chrIV 7,971,993	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR001920 (Asp/Glu racemase), IPR009126 (Cholecystokinin receptor), IPR000276 (GPCR, rhodopsin-like)
34	M176.8	M176.8	n/a	chrII 9,437,409	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
35	flp-3	W07E11.2	n/a	chrX 10,092,469	flp-3 encodes nine copies of a GTMRFamide-containing peptide that is predicted to function as a neuropeptide that inhibits pharyngeal action potential in a manner similar to octopamine without having a significant effect on basal resting membrane potential; expressed in three pairs of neurons IL1D, OL1, URB.
36	C34B2.3	C34B2.3	n/a	chrI 10,673,805	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase)
37	F53A9.6	F53A9.6	n/a	chrX 8,713,583	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen)
38	C07E3.3	C07E3.3	n/a	chrII 10,355,550	contains similarity to Ambrosia artemisiifolia Pollen allergen Amb a 1.2 precursor (Antigen E) (Antigen Amb a I).; SW:MP12_AMBAR
39	F21F3.1	F21F3.1	n/a	chrI 4,909,304	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR000720 (Peptidyl-glycine alpha-amidating monooxygenase), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013017 (NHL repeat, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR001258 (NHL repeat)
40	ZC443.4	ZC443.4	n/a	chrV 12,818,211	contains similarity to Homo sapiens Isoform 4 of AT-rich interactive domain-containing protein 4B; ENSEMBL:ENSP00000375729
41	F35A5.2	F35A5.2	n/a	chrX 3,805,400
42	F46B3.14	F46B3.14	n/a	chrV 20,626,135	contains similarity to Interpro domain IPR003645 (Follistatin-like, N-terminal)
43	F17E9.3	F17E9.3	n/a	chrIV 8,355,135
44	nnt-1	C15H9.1	n/a	chrX 6,124,888	nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial.
45	F37C4.8	F37C4.8	n/a	chrIV 3,880,246
46	drn-1	C54A12.4	n/a	chrII 5,271,026	C. elegans DRN-1 protein; contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
47	C09G5.7	C09G5.7	n/a	chrII 10,715,547	contains similarity to Homo sapiens Putative uncharacterized protein (Fragment); ENSEMBL:ENSP00000333119
48	sru-23	F36G9.6	n/a	chrV 15,971,479	C. elegans SRU-23 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR003839 (Protein of unknown function DUF215), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
49	W07A12.4	W07A12.4	n/a	chrII 9,150,253	contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF07707 (BTB And C-terminal Kelch) contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR011705 (BTB/Kelch-associated), IPR013089 (Kelch related)
50	C49C8.2	C49C8.2	n/a	chrIV 8,651,405