UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	scl-14	F09E8.5	8e-124	chrIV 13,166,113	C. elegans SCL-14 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
2	flp-21	C26F1.10	n/a	chrV 7,793,674	flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
3	nlp-3	F48C11.3	n/a	chrX 13,178,076	nlp-3 encodes a neuropeptide-like protein of the GFxGF family with similarity to orcokinins, highly conserved peptides native to crustaceans that enhance hindgut contractions; NLP-3 is expressed in neurons in the head, pharynx, and vulva, and in the intestine; the precise role of NLP-3 in nervous system function and development is not yet clear.
4	R11D1.3	R11D1.3	n/a	chrV 12,711,700	contains similarity to Proteus mirabilis Hypothetical protein (Fragment).; TR:O86985
5	flp-19	M79.4	n/a	chrX 10,605,248	C. elegans FLP-19 protein ;
6	nlp-1	C01C4.1	n/a	chrX 3,727,992	nlp-1 encodes a predicted neuropeptide-like protein of the MSFamide family with similarity to Aplysia californica (sea hare) buccalin, a neuropeptide that regulates acetylcholine-induced muscle contraction; NLP-1 is expressed in the phasmid PHB tail sensory neuron, lateral neurons, head neurons, and the intestine; the precise role of NLP-1 in nervous system function and development is not yet known.
7	sul-2	D1014.1	n/a	chrV 8,158,775	sul-2 is orthologous to the human gene ARYLSULFATASE A (ARSA; OMIM:250100), which when mutated leads to metachromatic leukodystrophy.
8	ins-18	T28B8.2	n/a	chrI 8,148,533	ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only two C. elegans insulins that contain a C peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 induces dauer arrest at 26 degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 functions to antagonize DAF-2 receptor signaling; ins-18::gfp reporters are expressed in neurons and the intestine.
9	nlp-8	D2005.2	n/a	chrI 7,801,131	C. elegans NLP-8 protein ;
10	F43G9.5	F43G9.5	n/a	chrI 8,615,863	F43G9.5 encodes a NUDIX hydrolase that that inhibits DHC-1 in vivo, and is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; F43G9.5(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F43G9.5 negatively regulates dynein; while loss of F43G9.5 function has no obvious effect on lifespan, dauer formation, or fat storage, F43G9.5 is required for embryonic development, fertility, and general health in mass RNAi assays.
11	snt-4	T23H2.2	n/a	chrI 6,438,658	C. elegans SNT-4 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
12	F52E1.8	F52E1.8	n/a	chrV 8,393,368	contains similarity to Pfam domains PF00300 (Phosphoglycerate mutase family) , PF00328 (Histidine acid phosphatase) contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR013078 (Phosphoglycerate mutase)
13	nlp-37	F48B9.4	n/a	chrX 2,163,570	C. elegans NLP-37 protein ;
14	flp-7	F49E10.3	n/a	chrX 5,886,304	flp-7 encodes an MVRFamide-containing peptide that, upon injection into A. suum, produces paralysis and loss of locomotory waveforms, increased body length, and decreased cAMP production.
15	C39D10.2	C39D10.2	n/a	chrX 7,889,123
16	F21F3.1	F21F3.1	n/a	chrI 4,909,304	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR000720 (Peptidyl-glycine alpha-amidating monooxygenase), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013017 (NHL repeat, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR001258 (NHL repeat)
17	tsp-1	C02F5.8	n/a	chrIII 8,238,638	C. elegans TSP-1 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013305 (ABC transporter, ABCB2), IPR003091 (Voltage-dependent potassium channel)
18	ida-1	B0244.2	n/a	chrIII 5,760,627	ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles.
19	K12B6.4	K12B6.4	n/a	chrV 6,280,741
20	flp-3	W07E11.2	n/a	chrX 10,092,469	flp-3 encodes nine copies of a GTMRFamide-containing peptide that is predicted to function as a neuropeptide that inhibits pharyngeal action potential in a manner similar to octopamine without having a significant effect on basal resting membrane potential; expressed in three pairs of neurons IL1D, OL1, URB.
21	F58B4.3	F58B4.3	n/a	chrV 10,930,269	contains similarity to Homo sapiens similar to bA88M19.1 (EGF-like-domain multiple 5 protein); ENSEMBL:ENSP00000223618
22	nlp-14	D1009.4	n/a	chrX 8,918,369	C. elegans NLP-14 protein; contains similarity to Interpro domain IPR005829 (Sugar transporter, conserved site)
23	R06F6.7	R06F6.7	n/a	chrII 10,811,543	contains similarity to Saccharomyces cerevisiae FLO5- and FLO8-determined flocculation are considerably less sensitive to mannose than FLO1-determined flocculation.; SGD:YHR211W
24	flp-13	F33D4.3	n/a	chrIV 7,697,747	C. elegans FLP-13 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
25	lys-3	Y22F5A.6	n/a	chrV 10,282,795	lys-3 encodes one of a family of ten C. elegans lysozyme genes that are homologous to lysozymes in the amoeboid protozoon Entamoeba histolytica.
26	sbt-1	T03D8.3	n/a	chrV 20,823,688	C. elegans SBT-1 protein; contains similarity to Pfam domain PF05281 Neuroendocrine protein 7B2 precursor (Secretogranin V) contains similarity to Interpro domain IPR007945 (Neuroendocrine 7B2 precursor)
27	C47D2.1	C47D2.1	n/a	chrX 8,215,243
28	B0294.1	B0294.1	n/a	chrX 1,897,093
29	ttr-23	T21C9.8	n/a	chrV 10,589,462	C. elegans TTR-23 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
30	ins-30	ZC334.2	n/a	chrI 14,035,617	ins-30 encodes an insulin-like peptide.
31	C54C6.5	C54C6.5	n/a	chrIII 3,549,652	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_4440.; TR:Q98QC2
32	numr-2	F08F8.1	n/a	chrIII 7,365,432	C. elegans NUMR-2 protein ;
33	K06A4.2	K06A4.2	n/a	chrV 9,487,363	contains similarity to Pfam domains PF00293 (NUDIX domain) , PF05026 (Dcp2, box A domain) contains similarity to Interpro domains IPR015797 (NUDIX), IPR007722 (Dcp2, box A), IPR000086 (NUDIX hydrolase, core)
34	nlp-15	CC4.2	n/a	chrI 12,991,841	C. elegans NLP-15 protein ; contains similarity to Procambarus clarkii Orcokinin peptides type A precursor [Contains: Orcomyotropin-likespeptide; Orcokinin; Orcokinin-like peptide].; SW:Q9NL83
35	cyp-14A5	F08F3.7	n/a	chrV 5,422,142	cyp-14A5 encodes a member of the cytochrome P450 family.
36	C17H12.10	C17H12.10	n/a	chrIV 6,808,208
37	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
38	C02B8.3	C02B8.3	n/a	chrX 8,139,820
39	cal-2	C18E9.1	n/a	chrII 8,961,053	cal-2 encodes a calmodulin homolog required for embryonic development or viability; CAL-2 is closely similar to its paralogs CAL-1, CAL-3, CAL-4 and CMD-1.
40	ttr-29	R90.4	n/a	chrV 12,906,429	C. elegans TTR-29 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
41	F20B6.6	F20B6.6	n/a	chrX 4,201,908	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
42	pqn-48	K07D4.8	n/a	chrII 4,040,965	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
43	fipr-23	C37A5.4	n/a	chrI 14,153,722	C. elegans FIPR-23 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
44	ZK353.4	ZK353.4	n/a	chrIII 8,388,992	contains similarity to Schizosaccharomyces pombe Uncharacterized serine/threonine-rich protein PB15E9.01c precursor.; SW:Q8TFG9
45	flp-5	C03G5.7	n/a	chrX 8,529,581	flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms; expressed in the sensory neurons ASE and PVM.
46	xbx-3	M04D8.6	n/a	chrIII 10,036,315	C. elegans XBX-3 protein ;
47	fipr-22	C37A5.2	n/a	chrI 14,155,893	C. elegans FIPR-22 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
48	K02A6.2	K02A6.2	n/a	chrX 8,224,536
49	T26G10.5	T26G10.5	n/a	chrIII 9,426,015	contains similarity to Streptococcus pyogenes Hypothetical protein SPy0952.; TR:Q9A032
50	C10G11.1	C10G11.1	n/a	chrI 6,307,930