UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	drh-3	D2005.5	0	chrI 7,823,605	drh-3 encodes a DExH-box helicase.
2	R105.1	R105.1	n/a	chrIV 4,635,811	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
3	math-15	C16C4.5	n/a	chrII 1,867,089	C. elegans MATH-15 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
4	C49C3.10	C49C3.10	n/a	chrIV 17,337,847	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000215 (Protease inhibitor I4, serpin), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
5	C46H11.2	C46H11.2	n/a	chrI 5,051,289	contains similarity to Pfam domains PF00743 (Flavin-binding monooxygenase-like) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000960 (Flavin-containing monooxygenase FMO), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
6	C53D6.7	C53D6.7	n/a	chrIV 9,035,988	contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
7	sra-29	F18C5.8	n/a	chrII 6,575,011	C. elegans SRA-29 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
8	F22F7.2	F22F7.2	n/a	chrV 2,125,082	contains similarity to Pfam domain PF03435 Saccharopine dehydrogenase contains similarity to Interpro domains IPR005097 (Saccharopine dehydrogenase), IPR016040 (NAD(P)-binding)
9	C05A9.3	C05A9.3	n/a	chrX 10,830,625	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
10	clh-6	R07B7.1	n/a	chrV 12,061,778	clh-6 encodes a voltage-gated chloride channel orthologous to the human CLCN7 chloride channel (OMIM:602727, which when mutated lead to osteopetrosis); although the precise role of CLH-6 in C. elegans development and/or behavior is not yet known, CLH-6 expression is detected in two GABA-ergic neurons, RMEL and RMER, suggesting that CLH-6 could play a role in membrane excitability and/or GABA packaging; as CLH-6 is also detected in many non-neuronal tissues, such as the gut and body wall muscle, it could also have a broader role in such as processes as transepithelial transport and muscle excitation.
11	F56B3.8	F56B3.8	n/a	chrIV 774,932	contains similarity to Pfam domains PF00181 (Ribosomal Proteins L2, RNA binding domain) , PF03947 (Ribosomal Proteins L2, C-terminal domain) contains similarity to Interpro domains IPR002171 (Ribosomal protein L2), IPR008991 (Translation protein SH3-like), IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR014722 (Translation protein SH3-like, subgroup)
12	srt-70	B0238.6	n/a	chrV 5,258,776	C. elegans SRT-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
13	W03A5.6	W03A5.6	n/a	chrIII 5,440,330
14	gtl-1	C05C12.3	n/a	chrIV 11,254,145	gtl-1 encodes a TRPM subfamily member of the TRP channel family that affects the periodicity of the defecation cycle in combination with gon-2; expression includes the intestine.
15	M01E5.2	M01E5.2	n/a	chrI 13,278,606	contains similarity to Pfam domains PF01018 (GTP1/OBG) , PF01926 (GTPase of unknown function) contains similarity to Interpro domains IPR014100 (GTP-binding protein Obg/CgtA), IPR005225 (Small GTP-binding protein), IPR006169 (GTP1/OBG subdomain), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG)
16	W03H9.2	W03H9.2	n/a	chrII 14,144,403	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000046554
17	T26C5.4	T26C5.4	n/a	chrII 9,249,704	contains similarity to Encephalitozoon cuniculi SER/THR protein phosphatase 2-A (EC 3.1.3.16) (Serine/threoninesprotein phosphatase).; TR:Q8SS50
18	F09G8.5	F09G8.5	n/a	chrIII 8,256,200	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal), IPR010916 (TonB box, conserved site)
19	vhl-1	F08G12.4	n/a	chrX 11,307,692	vhl-1 is orthologous to the mammalian tumor suppressor gene Von Hippel-Landau syndrome (VHL; OMIM:193300), which is part of a ubiquitylation complex targetting proteins for proteasomal degradation.
20	W04A8.2	W04A8.2	n/a	chrI 13,840,793	contains similarity to Streptococcus pyogenes Putative type I site-specific deoxyribonuclease hsdS subunit.; TR:Q8K5V9
21	F18A12.7	F18A12.7	n/a	chrII 3,412,942	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
22	C34C12.2	C34C12.2	n/a	chrIII 3,458,263	contains similarity to Homo sapiens Putative protein TPRXL; ENSEMBL:ENSP00000322097
23	Y52B11A.10	Y52B11A.10	n/a	chrI 11,045,757	contains similarity to Pfam domains PF02854 (MIF4G domain) , PF02847 (MA3 domain) contains similarity to Interpro domains IPR003890 (MIF4G-like, type 3), IPR016021 (MIF4-like, type 1/2/3), IPR003891 (Initiation factor eIF-4 gamma, MA3), IPR016024 (Armadillo-type fold)
24	clec-265	M02F4.7	n/a	chrX 3,032,455	C. elegans CLEC-265 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
25	kin-4	C10C6.1	n/a	chrIV 11,441,819	C. elegans KIN-4 protein; contains similarity to Pfam domains PF08926 (Domain of unknown function (DUF1908)) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR015022 (Region of unknown function DUF1908), IPR000719 (Protein kinase, core), IPR001478 (PDZ/DHR/GLGF), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
26	K08C7.7	K08C7.7	n/a	chrIV 10,665,006	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
27	str-78	Y40H7A.1	n/a	chrIV 15,145,449	C. elegans STR-78 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	C29F7.7	C29F7.7	n/a	chrX 13,442,218	contains similarity to Peromyscus maniculatus Alcohol dehydrogenase 2 (EC 1.1.1.1).; SW:ADH2_PERMA
29	F20D12.2	F20D12.2	n/a	chrIV 7,951,094	contains similarity to Pfam domain PF03399 SAC3/GANP/Nin1/mts3/eIF-3 p25 family contains similarity to Interpro domain IPR005062 (SAC3/GANP/Nin1/mts3/eIF-3 p25)
30	fbxa-200	T07D3.1	n/a	chrII 905,248	C. elegans FBXA-200 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
31	tag-324	C27C12.5	n/a	chrX 14,850,888	C. elegans TAG-324 protein; contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
32	cul-5	ZK856.1	n/a	chrV 10,181,305	cul-5 encodes a cullin, orthologous to vasopressin-activated calcium-mobilizing receptor-1 in mammals, that is thought to regulate the cell cycle by virtue of its paralogy to cul-1 and cul-2; however, CUL-5 is dispensable for viability and gross morphology in mass RNAi screens, and does not appear to interact with any of 17 Skp1-related proteins (SKR-1 through SKR-21).
33	C12D12.5	C12D12.5	n/a	chrX 3,505,953	contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG)
34	B0334.6	B0334.6	n/a	chrII 11,512,193	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
35	C41A3.1	C41A3.1	n/a	chrX 5,427,831	contains similarity to Pfam domains PF02801 (Beta-ketoacyl synthase, C-terminal domain) (5), PF01370 (NAD dependent epimerase/dehydratase family) , PF08659 (KR domain) (2), PF00501 (AMP-binding enzyme) , PF00668 (Condensation domain) , PF00106 (short chain dehydrogenase) , PF00109 (Beta-ketoacyl synthase, N-terminal domain) (5), PF00550 (Phosphopantetheine attachment site) (8), PF00698 (Acyl transferase domain) (2)contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR006163 (Phosphopantetheine-binding), IPR001242 (Condensation domain), IPR016038 (Thiolase-like, subgroup), IPR013968 (Polyketide synthase, KR), IPR000794 (Beta-ketoacyl synthase), IPR001509 (NAD-dependent epimerase/dehydratase), IPR014031 (Beta-ketoacyl synthase, C-terminal), IPR014043 (Acyl transferase), IPR014030 (Beta-ketoacyl synthase, N-terminal), IPR008262 (Lipase, active site), IPR006162 (Phosphopantetheine attachment site), IPR000873 (AMP-dependent synthetase and ligase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016039 (Thiolase-like), IPR016040 (NAD(P)-binding), IPR009081 (Acyl carrier protein-like), IPR001227 (Acyl transferase region)
36	ddl-2	Y48E1B.1	n/a	chrII 13,545,140	C. elegans DDL-2 protein; contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000381 (Inhibin, beta B subunit), IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
37	C32E8.9	C32E8.9	n/a	chrI 3,796,306	contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
38	end-1	F58E10.2	n/a	chrV 13,986,046	end-1 encodes a GATA-like transcription factor sufficient to initiate endoderm differentiation and binds to the canonical target DNA sequence WGATAR with specificity similar to GATA-1 and D4 transcription factors; its expression bypasses requirement for maternal SKN-1 and the maternal Wnt signaling pathway in endoderm formation and it activates endoderm differentiation in isolated Xenopus ectoderm.
39	str-187	F26D10.8	n/a	chrIV 17,266,207	C. elegans STR-187 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000539 (Frizzled protein)
40	K04G11.1	K04G11.1	n/a	chrX 14,335,998	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
41	srsx-8	F52F10.5	n/a	chrV 1,552,074	C. elegans SRSX-8 protein ;
42	C44E4.5	C44E4.5	n/a	chrI 4,607,929	contains similarity to Pfam domain PF04969 CS domain contains similarity to Interpro domains IPR008978 (HSP20-like chaperone), IPR017447 (CS), IPR007052 (CS domain)
43	C45E5.1	C45E5.1	n/a	chrIV 5,745,740	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR005834 (Haloacid dehalogenase-like hydrolase)
44	W08D2.5	W08D2.5	n/a	chrIV 9,821,001	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR000150 (Cof protein), IPR005834 (Haloacid dehalogenase-like hydrolase)
45	lips-1	F45E6.4	n/a	chrX 12,494,285	C. elegans LIPS-1 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
46	Y47H9C.9	Y47H9C.9	n/a	chrI 11,900,113	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
47	ttll-5	C55A6.2	n/a	chrV 11,510,749	ttll-5 encodes a putative tubulin polyglutamylase orthologous to human TTLL5; TTLL-5 is required for embryonic development and fertility; by orthology, TTLL-5 is expected to initiate glutamyl chains rather than elongating them, to prefer alpha-tubulin over beta-tubulin as a substrate, and to have non-tubulin substrates.
48	pbo-4	K09C8.1	n/a	chrX 10,956,107	pbo-4 encodes a sodium/proton exchanger (also known as nhx-7), with a potential Ca[2+]/calmodulin binding domain in its C-terminal cytosolic region that could mediate calcium signaling; PBO-4 is expressed in the basolateral membrane of posterior intestinal cells; PBO-4 is required for normal posterior body muscle contraction (pBoc) during the defecation cycle; PBO-4 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton; specifically, PBO-4 may enable intercellular signals from intestinal cells (by secreting protons which then might activate PBO-5 in adjacent muscle cells).
49	D1053.4	D1053.4	n/a	chrX 11,722,796	contains similarity to Naja kaouthia Cytotoxin 5 (Cytotoxin II).; SW:CX5_NAJKA
50	ulp-4	C41C4.6	n/a	chrII 8,132,271	C. elegans ULP-4 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)