UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C54E10.3	C54E10.3	5e-167	chrV 18,812,207	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
2	fkh-3	C29F7.4	n/a	chrX 13,422,576	fkh-3 encodes one of 15 C. elegans forkhead transcription factors; loss of fkh-3 activity via RNAi, either singly or in combination with the closely related fkh-4 and fkh-5 genes, results in no obvious abnormalities, suggesting functional redundancy with other genes; an FKH-3 reporter fusion is expressed in most, but not all, cells of the early embryo from the 20- to the 200-cell stage.
3	T26H2.7	T26H2.7	n/a	chrV 19,220,389	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
4	F09C3.2	F09C3.2	n/a	chrI 14,273,068	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR005833 (Haloacid dehydrogenase/epoxide hydrolase), IPR005834 (Haloacid dehalogenase-like hydrolase)
5	F57A8.6	F57A8.6	n/a	chrV 10,072,890	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domain IPR002593 (Protein of unknown function DX)
6	C43C3.2	C43C3.2	n/a	chrX 9,695,245	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
7	F07F6.1	F07F6.1	n/a	chrII 5,439,042	contains similarity to Interpro domain IPR012677 (Nucleotide-binding, alpha-beta plait)
8	sre-26	Y57A10C.4	n/a	chrII 12,419,774	C. elegans SRE-26 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
9	srbc-14	T05E12.2	n/a	chrV 17,071,071	C. elegans SRBC-14 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
10	srg-68	ZC317.5	n/a	chrV 5,464,597	C. elegans SRG-68 protein ;
11	R07E3.7	R07E3.7	n/a	chrX 10,343,094	contains similarity to Borrelia burgdorferi Outer surface protein C (Fragment).; TR:Q93Q85
12	T26E4.3	T26E4.3	n/a	chrV 15,783,606	contains similarity to Pfam domain PF01531 (Glycosyl transferase family 11)
13	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
14	F28H7.4	F28H7.4	n/a	chrV 10,746,917	contains similarity to Interpro domain IPR011893 (SelT/selW/selH selenoprotein)
15	F22B7.3	F22B7.3	n/a	chrIII 8,649,167
16	W03F9.9	W03F9.9	n/a	chrV 139,558	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
17	T24C4.4	T24C4.4	n/a	chrIII 873,063	contains similarity to Pfam domain PF06653 Protein of unknown function (DUF1164) contains similarity to Interpro domains IPR008368 (Voltage-dependent calcium channel, gamma subunit), IPR009545 (Protein of unknown function DUF1164), IPR002229 (Blood group Rhesus C/E and D polypeptide)
18	sru-37	C50C10.1	n/a	chrV 9,806,002	C. elegans SRU-37 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
19	F37A4.5	F37A4.5	n/a	chrIII 6,712,464	contains similarity to Pfam domain PF01398 Mov34/MPN/PAD-1 family contains similarity to Interpro domains IPR000555 (Mov34/MPN/PAD-1), IPR006162 (Phosphopantetheine attachment site), IPR003639 (Mov34-1)
20	C53A5.5	C53A5.5	n/a	chrV 14,541,386	contains similarity to Pfam domains PF02888 (Calmodulin binding domain) , PF03530 (Calcium-activated SK potassium channel) , PF07885 (Ion channel) contains similarity to Interpro domains IPR004178 (Calmodulin-binding), IPR015449 (Potassium channel, calcium-activated, SK), IPR011996 (Potassium channel, calcium-activated, SK, conserved region), IPR003931 (Potassium channel, calcium-activated, SK, conserved region, subgroup), IPR013099 (Ion transport 2)
21	F58E6.1	F58E6.1	n/a	chrV 9,742,698	n/a
22	W03G1.5	W03G1.5	n/a	chrIV 505,834	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000694 (Proline-rich region), IPR002964 (Adhesive plaque protein)
23	pin-2	F07C6.1	n/a	chrIV 12,794,963	pin-2 encodes a LIM domain-containing protein that, along with UNC-97, comprises the two C. elegans members of the PINCH family of predicted adapter proteins; based upon its similarity to Drosophila and vertebrate members of the PINCH family, PIN-2 is predicted to play a role in regulation of cell morphology, motility, and survival, but as loss of pin-2 via large-scale RNAi results in no obvious defects, the precise role of PIN-2 in C. elegans development and/or behavior is not yet known; a PIN-2::GFP fusion protein is first expressed in embryos just prior to hatching and in early larvae is seen in several neurons, including the PVT neuron, and in intestinal cells; during postembryonic development, neuronal expression continues, whereas intestinal expression gradually declines; PIN-2 localizes to the cytoplasm and to the nucleus, and in neurons, is seen in axonal processes and varicosities.
24	C30A5.4	C30A5.4	n/a	chrIII 8,222,929	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
25	R09A8.5	R09A8.5	n/a	chrX 12,639,412	contains similarity to Varroa destructor NADH dehydrogenase subunit 4L.; TR:Q8HCK4
26	numr-2	F08F8.1	n/a	chrIII 7,365,432	C. elegans NUMR-2 protein ;
27	ZK697.3	ZK697.3	n/a	chrV 1,729,883	contains similarity to Interpro domain IPR001411 (Tetracycline resistance protein, TetB)
28	ssu-1	Y113G7A.11	n/a	chrV 20,126,167	ssu-1 encodes, by alternative splicing, two isoforms of a cytosolic alcohol sulfotransferase that interacts in the ASJ amphid neurons with the stomatins UNC-1 and UNC-24; the longer SSU-1 isoform is required for normal anesthetic sensitivity and unc-1 phenotypes; ssu-1(fc73) suppresses the anesthetic sensitivity and uncoordinated phenotypes of unc-1 and unc-24 mutants; ssu-1(fc73), along with daf-12, suppresses the synthetic constitutive dauer-formation phenotype of fc83;unc-24(e138) mutants; ssu-1 suppression is rescued by transgenic expression of SSU-1 in the ASJ neurons alone, implying that sulfation is required for an endocrine function; SSU-1 protein sulfates 4-nitrophenol and 2-naphthol substrates, and bisphenol A, but not monoamines or hydroxysteroids; SSU-1 is cytosolic, but its activity is not detectable in cytosolic extracts; ssu-1 is strongly expressed in embryos, growing larvae, and dauer larvae; ssu-1 expression is increased in daf-2; by homology with other sulfotransferases, SSU-1 may link sulfates to the alcohol group of small molecules as part of detoxification or signal transduction.
29	F53E10.4	F53E10.4	n/a	chrV 2,593,813
30	fbxa-129	F59A1.8	n/a	chrV 17,656,084	C. elegans FBXA-129 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
31	str-27	T23D5.1	n/a	chrV 15,734,895	C. elegans STR-27 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	C54G4.5	C54G4.5	n/a	chrI 7,996,207
33	K12B6.4	K12B6.4	n/a	chrV 6,280,741
34	T18D3.5	T18D3.5	n/a	chrX 12,464,020	contains similarity to Streptococcus pneumoniae Com protein (Fragment).; TR:Q9RIM4
35	T06D4.3	T06D4.3	n/a	chrII 3,389,928	T06D4.3 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T06D4.3 has no clear orthologs in other organisms.
36	F09C6.3	F09C6.3	n/a	chrV 16,879,465	contains similarity to Saccharomyces cerevisiae DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; SGD:YMR173W
37	F35F10.12	F35F10.12	n/a	chrV 3,314,352	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000694 (Proline-rich region), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
38	gst-8	F11G11.1	n/a	chrII 4,884,139	gst-8 encodes a predicted glutathione S-transferase.
39	nhr-30	C25E10.1	n/a	chrV 9,046,045	C. elegans NHR-30 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
40	C18G1.1	C18G1.1	n/a	chrV 4,779,553
41	Y42A5A.4	Y42A5A.4	n/a	chrV 11,106,364	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
42	B0222.2	B0222.2	n/a	chrV 9,136,662	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domain IPR001204 (Phosphate transporter)
43	lgc-20	B0491.4	n/a	chrII 11,341,749	C. elegans LGC-20 protein; contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
44	glb-27	W01C9.5	n/a	chrII 8,548,030	glb-27 encodes a globin whose expression is probably induced by anoxia in a HIF-1-dependent manner; glb-27 transcription is higher in L3 and dauers than in young adults; glb-27 has no obvious function in mass RNAi assays.
45	fbxb-1	T26H2.1	n/a	chrV 19,240,953	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
46	F33E2.6	F33E2.6	n/a	chrI 12,589,287	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
47	Y116A8A.6	Y116A8A.6	n/a	chrIV 16,826,929	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
48	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
49	C28H8.8	C28H8.8	n/a	chrIII 5,887,890	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
50	mif-3	F13G3.9	n/a	chrI 7,313,193	C. elegans MIF-3 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)