UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C50F4.2	C50F4.2	0	chrV 9,533,151	C50F4.2 encodes a putative 6-phosphofructokinase, paralogous to Y71H10A.1; C50F4.2 is required for fertility, full body size, and normally rapid growth in mass RNAi assays; C50F4.2 transcripts are enriched during spermatogenesis.
2	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
3	Y39A1A.14	Y39A1A.14	n/a	chrIII 10,649,949	contains similarity to Pfam domain PF03587 Nep1 ribosome biogenesis protein contains similarity to Interpro domain IPR005304 (Suppressor Mra1)
4	C09G1.4	C09G1.4	n/a	chrX 15,992,503	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
5	K11C4.1	K11C4.1	n/a	chrV 6,897,709	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
6	M117.4	M117.4	n/a	chrIV 11,832,142	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
7	C36H8.1	C36H8.1	n/a	chrIV 12,743,886	contains similarity to Pfam domains PF03134 (TB2/DP1, HVA22 family) , PF00635 (MSP (Major sperm protein) domain) contains similarity to Interpro domains IPR008962 (PapD-like), IPR000694 (Proline-rich region), IPR000535 (Major sperm protein), IPR004345 (TB2/DP1 and HVA22 related protein)
8	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
9	Y38H6C.15	Y38H6C.15	n/a	chrV 20,530,900	contains similarity to Interpro domain IPR006017 (Caldesmon)
10	F59A7.9	F59A7.9	n/a	chrV 2,005,893	contains similarity to Pfam domain PF00291 Pyridoxal-phosphate dependent enzyme contains similarity to Interpro domains IPR005856 (Cysteine synthase K/M), IPR001216 (Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site), IPR005859 (Cysteine synthase A), IPR001926 (Pyridoxal phosphate-dependent enzyme, beta subunit), IPR016040 (NAD(P)-binding)
11	ZK484.7	ZK484.7	n/a	chrI 6,095,825	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
12	ari-1	C27A12.8	n/a	chrI 6,059,904	C. elegans ARI-1 protein; contains similarity to Pfam domain PF01485 IBR domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR002867 (Zinc finger, C6HC-type)
13	Y106G6D.4	Y106G6D.4	n/a	chrI 10,115,663	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
14	B0207.7	B0207.7	n/a	chrI 5,946,551	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
15	T15B12.2	T15B12.2	n/a	chrIII 5,300,917	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
16	fbxa-90	Y102A5C.19	n/a	chrV 16,967,704	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
17	wht-5	F19B6.4	n/a	chrIV 12,338,972	C. elegans WHT-5 protein; contains similarity to Pfam domains PF01061 (ABC-2 type transporter) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR003593 (AAA+ ATPase, core), IPR013525 (ABC-2 type transporter)
18	F27E5.3	F27E5.3	n/a	chrII 10,142,746	contains similarity to Homo sapiens Isoform 1 of Cell division cycle 2-related protein kinase 7; ENSEMBL:ENSP00000300647
19	tag-141	C30H6.2	n/a	chrIV 17,365,684	tag-141/C30H6.2 encodes a putative zinc transporter orthologous to human SLC39A4 (OMIM:607059, mutated in acrodermatitis enteropathica).
20	B0280.11	B0280.11	n/a	chrIII 7,137,323	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
21	Y113G7B.14	Y113G7B.14	n/a	chrV 20,223,220	contains similarity to Pfam domains PF04851 (Type III restriction enzyme, res subunit) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal)
22	C55C3.3	C55C3.3	n/a	chrIV 5,686,761	contains similarity to Trypanosoma cruzi Trans-sialidase, putative.; TR:Q4E0H9
23	C03B8.3	C03B8.3	n/a	chrIII 7,712,627
24	Y53C10A.10	Y53C10A.10	n/a	chrI 12,024,518	contains similarity to Interpro domain IPR000694 (Proline-rich region)
25	K07E12.2	K07E12.2	n/a	chrIII 6,737,547
26	ace-3	Y48B6A.8	n/a	chrII 14,207,809	ace-3 encodes one of four C. elegans acetylcholinesterases (AChE); ACE-3 represents ~5% of the total AChE activity in C. elegans and in vitro, hydrolyzes acetylthio-, butyrylthio-, and propionylthiocholine substrates with equal efficiency; although loss-of-function mutations in ace-3 result in no obvious defects, animals doubly mutant with ace-1 or ace-2 have slight defects in backward locomotion and animals triply mutant for ace-1, -2, and -3 arrest as unhatched, yet fully developed, embryos; ace-3 is the downstream gene in an operon with a fourth AChE-encoding gene, ace-4, and transcriptional reporter fusions with ace-4 upstream sequences direct expression in pharyngeal muscles pm3, 4, 5, and 7, the two CAN (canal associated neuron) cells, midbody dorsal body wall muscles in larvae, and several neurons in the head and anal ganglion
27	Y54G9A.4	Y54G9A.4	n/a	chrII 13,714,353	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
28	H08M01.1	H08M01.1	n/a	chrIV 13,835,341	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR003071 (Orphan nuclear receptor, HMR type)
29	F13C5.5	F13C5.5	n/a	chrX 606,710
30	D2089.2	D2089.2	n/a	chrII 10,660,588	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
31	T08D10.3	T08D10.3	n/a	chrX 11,956,831	contains similarity to Homo sapiens Hypothetical protein KIAA1681; ENSEMBL:ENSP00000316543
32	T22D1.12	T22D1.12	n/a	chrIV 6,930,087	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
33	C28A5.6	C28A5.6	n/a	chrIII 4,426,610	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
34	K07A1.4	K07A1.4	n/a	chrI 9,589,308	contains similarity to Mycobacterium tuberculosis TcrZ protein (Fragment).; TR:Q50810
35	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
36	C33C12.4	C33C12.4	n/a	chrII 2,165,992
37	wrt-3	F38E11.7	n/a	chrIV 9,476,571	wrt-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a region of low-complexity sequence; WRT-3 is expressed in the trinucleate pharyngeal gland cell g1 beginning at the three-fold stage of embryogenesis, in seam cells and hypodermis, and in single muscle cells and the distal tip cells of late stage larvae and adults; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-3 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
38	T05A8.1	T05A8.1	n/a	chrII 2,709,077
39	F39E9.4	F39E9.4	n/a	chrII 3,284,898	F39E9.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F39E9.4 has no clear orthologs in other organisms.
40	Y48A6B.8	Y48A6B.8	n/a	chrIII 11,028,225	contains similarity to Interpro domains IPR003547 (Serine/threonine protein kinase, yersinia), IPR013022 (Xylose isomerase-like, TIM barrel)
41	Y38H8A.4	Y38H8A.4	n/a	chrIV 13,471,382	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
42	lin-52	ZK632.13	n/a	chrIII 9,824,348	lin-52 encodes a novel protein that is most closely related to the Drosophila melanogaster CG15929 protein and the human protein XP_040376; lin-52 is a class B synthetic multivulva (synMuv) gene that appears to function with lin-35/Rb to negatively regulate vulval development; in addition, lin-52 is also required for germline and larval development.
43	R09H10.2	R09H10.2	n/a	chrIV 10,606,027	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
44	srx-78	C01G10.3	n/a	chrV 15,096,226	C. elegans SRX-78 protein
45	C16D9.5	C16D9.5	n/a	chrV 8,244,484	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
46	C06C3.8	C06C3.8	n/a	chrII 9,388,665	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domains IPR005020 (Protein of unknown function DUF278), IPR001984 (Peptidase S16, Lon protease), IPR006578 (MADF)
47	let-75	R06C7.10	n/a	chrI 7,263,197	let-75 encodes a pharynx-specific type II myosin heavy chain (MHC D); LET-75 is required for pharyngeal muscle contraction and thus for normal feeding behavior and post-embryonic development; in vitro, the LET-75 tail domain interacts with ITR-1, an IP3 receptor, and this interaction has been proposed to mediate, in vivo, increased pharnygeal pumping in response to food; LET-75 is expressed exclusively in pharyngeal muscle.
48	spe-15	F47G6.4	n/a	chrI 1,456,004	spe-15 encodes an unconventional myosin, and is homologous to both Drosophila and mouse myosin VI; spe-15 was identified in screens for mutants that have defective spermatogenesis; spe-15 is required during the terminal stages of spermatogenesis for the asymmetric partitioning of organelles like the mitochondria and for the proper partitioning of specialized structures called the fibrous-body membranous organelles into the spermatid; mutant spe-15 spermatids contain actin filaments in contrast to wild-type which lack them; spe-15 is also required for the proper morphology and activation of the spermatid; the human gene MYOSIN VI (MYO6; OMIM:600970), when mutated leads to disease that affects hearing.
49	ubq-2	ZK1010.1	n/a	chrIII 12,978,145	ubq-2 encodes a bifunctional protein that contains two domains; an N-terminal ubiquitin peptide, and a C-terminal large ribosomal subunit protein L40 peptide.
50	srbc-44	ZC455.9	n/a	chrV 12,787,889	C. elegans SRBC-44 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)